Frederic J. Seidler

DUKE, School of Medicine, Pharmacology & Cancer Biology

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Frederic J. Seidler

• Organizations
  Duke University
  
  School of Medicine
  
  Pharmacology & Cancer Biology
  
  

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Theodore A. Slotkin; Jennifer Card; Alice Infante; Frederic J. Seidler

  Prenatal dexamethasone augments the sex-selective developmental neurotoxicity of chlorpyrifos: Implications for vulnerability after pharmacotherapy for preterm labor

  Neurotoxicology and Teratology. 2013;37:1-12.
  0

• 2.

  2013

  Theodore A. Slotkin; Jennifer Card; Alice Infante; Frederic J. Seidler

  BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells

  Neurotoxicology and Teratology. 2013;37:13-17.
  0

• 3.

  2013

  Theodore A. Slotkin; Frederic J. Seidler

  Terbutaline impairs the development of peripheral noradrenergic projections: Potential implications for autism spectrum disorders and pharmacotherapy of preterm labor

  Neurotoxicology and Teratology. 2013;36:91-96.
  0

• 4.

  2012

  Theodore A. Slotkin; Jennifer Card; Frederic J. Seidler

  Chlorpyrifos developmental neurotoxicity: Interaction with glucocorticoids in PC12 cells

  Neurotoxicology and Teratology. 2012;34(5):505-512.
  1

• 5.

  2012

  Theodore A. Slotkin; Frederic J. Seidler

  Does mechanism matter? Unrelated neurotoxicants converge on cell cycle and apoptosis during neurodifferentiation

  Neurotoxicology and Teratology. 2012;34(4):395-402.
  0

• 6.

  2012

  Theodore A. Slotkin; Frederic J. Seidler

  Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro

  Neurotoxicology and Teratology. 2012;34(2):232-241.
  5

• 7.

  2011

  Theodore A. Slotkin; Frederic J. Seidler

  Mimicking maternal smoking and pharmacotherapy of preterm labor: Fetal nicotine exposure enhances the effect of late gestational dexamethasone treatment on noradrenergic circuits

  Brain Research Bulletin. 2011;86(5-6):435-440.
  1

• 8.

  2011

  Theodore A. Slotkin; Frederic J. Seidler

  Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo

  Brain Research Bulletin. 2011;86(5-6):340-347.
  2

• 9.

  2011

  Christina M. Powers; Theodore A. Slotkin; Frederic J. Seidler; Appala R. Badireddy; Stephanie Padilla

  Silver nanoparticles alter zebrafish development and larval behavior: Distinct roles for particle size, coating and composition

  Neurotoxicology and Teratology. 2011;33(6):708-714.
  6

• 10.

  2011

  Laura V. Dishaw; Christina M. Powers; Ian T. Ryde; Simon C. Roberts; Frederic J. Seidler; Theodore A. Slotkin; Heather M. Stapleton

  Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells

  Toxicology and Applied Pharmacology. 2011;256(3):281-289.
  13

• 11.

  2011

  Frederic J. Seidler; Theodore A. Slotkin

  Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: Effects of organophosphates are distinct from those of glucocorticoids

  Brain Research Bulletin. 2011;85(3-4):225-230.
  4

• 12.

  2011

  Theodore A. Slotkin; Frederic J. Seidler; Eliot R. Spindel

  Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: Amelioration by Vitamin C

  Neurotoxicology and Teratology. 2011;33(3):431-434.
  6

• 13.

  2011

  Christina M. Powers; Edward D. Levin; Frederic J. Seidler; Theodore A. Slotkin

  Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes

  Neurotoxicology and Teratology. 2011;33(2):329-332.
  4

• 14.

  2011

  Christina M. Powers; Appala R. Badireddy; Ian T. Ryde; Frederic J. Seidler; Theodore A. Slotkin

  Silver nanoparticles compromise neurodevelopment in PC12 cells: Critical contributions of silver Ion, particle size, coating, and composition

  Environmental Health Perspectives. 2011;119(1):37-44.
  17

• 15.

  2010

  Theodore A. Slotkin; Frederic J. Seidler

  Diverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: Effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells

  Brain Research. 2010;1353:36-52.
  4

• 16.

  2010

  Theodore A. Slotkin; Doug Lobner; Frederic J. Seidler

  Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicants

  Brain Research Bulletin. 2010;83(1-2):76-83.
  6

• 17.

  2010

  Abayomi A. Adigun; Ian T. Ryde; Frederic J. Seidler; Theodore A. Slotkin

  Organophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells

  Brain Research. 2010;1329:36-44.
  4

• 18.

  2010

  Christina M. Powers; Jerry Yen; Elwood A. Linney; Frederic J. Seidler; Theodore A. Slotkin

  Silver exposure in developing zebrafish (Danio rerio): Persistent effects on larval behavior and survival

  Neurotoxicology and Teratology. 2010;32(3):391-397.
  15

• 19.

  2010

  Theodore A. Slotkin; Ian T. Ryde; Frederic J. Seidler

  Additive and synergistic effects of fetal nicotine and dexamethasone exposure on cholinergic synaptic function in adolescence and adulthood: Implications for the adverse consequences of maternal smoking and pharmacotherapy of preterm delivery

  Brain Research Bulletin. 2010;81(6):552-560.
  6

• 20.

  2010

  Abayomi A. Adigun; Nicola Wrench; Edward D. Levin; Frederic J. Seidler; Theodore A. Slotkin

  Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum

  Brain Research Bulletin. 2010;81(6):605-612.
  3

• 21.

  2010

  Edward D. Levin; Olga A. Timofeeva; Liwei Yang; Ann Petro; Ian T. Ryde; Nicola Wrench; Frederic J. Seidler; Theodore A. Slotkin

  Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging

  Behavioural Brain Research. 2010;208(2):319-327.
  8

• 22.

  2010

  Theodore A. Slotkin; Frederic J. Seidler

  Mimicking maternal smoking and pharmacotherapy of preterm labor: Interactions of fetal nicotine and dexamethasone on serotonin and dopamine synaptic function in adolescence and adulthood

  Brain Research Bulletin. 2010;82(1-2):124-134.
  7

• 23.

  2010

  Theodore A. Slotkin; Frederic J. Seidler

  Oxidative stress from diverse developmental neurotoxicants: Antioxidants protect against lipid peroxidation without preventing cell loss

  Neurotoxicology and Teratology. 2010;32(2):124-131.
  11

• 24.

  2010

  Abayomi A. Adigun; Nicola Wrench; Frederic J. Seidler; Theodore A. Slotkin

  Neonatal dexamethasone treatment leads to alterations in cell signaling cascades controlling hepatic and cardiac function in adulthood

  Neurotoxicology and Teratology. 2010;32(2):193-199.
  3

• 25.

  2010

  Abayomi A. Adigun; Frederic J. Seidler; Theodore A. Slotkin

  Disparate developmental neurotoxicants converge on the cyclic AMP signaling cascade, revealed by transcriptional profiles in vitro and in vivo

  Brain Research. 2010;1316:1-16.
  8

• 26.

  2010

  Abayomi A. Adigun; Nicola Wrench; Frederic J. Seidler; Theodore A. Slotkin

  Neonatal organophosphorus pesticide exposure alters the developmental trajectory of cell-signaling cascades controlling metabolism: Differential effects of diazinon and parathion

  Environmental Health Perspectives. 2010;118(2):210-215.
  9

• 27.

  2010

  T. Leon Lassiter; Ian T. Ryde; Edward D. Levin; Frederic J. Seidler; Theodore A. Slotkin

  Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits

  Brain Research Bulletin. 2010;81(1):85-91.
  9

• 28.

  2010

  Theodore A. Slotkin; Frederic J. Seidler; Fabio Fumagalli

  Unrelated developmental neurotoxicants elicit similar transcriptional profiles for effects on neurotrophic factors and their receptors in an in vitro model

  Neurotoxicology and Teratology. 2010;32(1):42-51.
  9

• 29.

  2010

  Christina M. Powers; Nicola Wrench; Ian T. Ryde; Amanda M. Smith; Frederic J. Seidler; Theodore A. Slotkin

  Silver impairs neurodevelopment: Studies in PC12 cells

  Environmental Health Perspectives. 2010;118(1):73-79.
  26

• 30.

  2009

  Theodore A. Slotkin; Nicola Wrench; Ian T. Ryde; T. Leon Lassiter; Edward D. Levin; Frederic J. Seidler

  Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: Modulation by a high-fat diet in adulthood

  Neurotoxicology and Teratology. 2009;31(6):390-399.
  4

• 31.

  2009

  Joseph Yanai; Adi Pinkas; Frederic J. Seidler; Ian T. Ryde; Eddy A. Van der Zee; Theodore A. Slotkin

  Neurobehavioral teratogenicity of sarin in an avian model

  Neurotoxicology and Teratology. 2009;31(6):406-412.
  2

• 32.

  2009

  Theodore A. Slotkin; Frederic J. Seidler

  Benzo[a]pyrene impairs neurodifferentiation in PC12 cells

  Brain Research Bulletin. 2009;80(1-2):17-21.
  9

• 33.

  2009

  Theodore A. Slotkin; Ian T. Ryde; Nicola Wrench; Jennifer A. Card; Frederic J. Seidler

  Nonenzymatic role of acetylcholinesterase in neuritic sprouting: Regional changes in acetylcholinesterase and choline acetyltransferase after neonatal 6-hydroxydopamine lesions

  Neurotoxicology and Teratology. 2009;31(3):183-186.
  6

• 34.

  2009

  Theodore.A. Slotkin; Frederic.J. Seidler

  Nicotine exposure in adolescence alters the response of serotonin systems to nicotine administered subsequently in adulthood

  Developmental Neuroscience. 2009;31(1-2):58-70.
  2

• 35.

  2009

  Theodore A. Slotkin; Frederic J. Seidler

  Protein kinase C is a target for diverse developmental neurotoxicants: Transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells

  Brain Research. 2009;1263:23-32.
  22

• 36.

  2009

  T. Leon Lassiter; Emiko A. MacKillop; Ian T. Ryde; Frederic J. Seidler; Theodore A. Slotkin

  Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells

  Brain Research Bulletin. 2009;78(6):313-322.
  15

• 37.

  2009

  Theodore Slotkin; Frederic Seidler

  Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells

  Brain Research Bulletin. 2009;78(4-5):211-225.
  17

• 38.

  2009

  Theodore A. Slotkin; Frederic J. Seidler

  Oxidative and excitatory mechanisms of developmental neurotoxicity: Transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 Cells

  Environmental Health Perspectives. 2009;117(4):587-596.
  28

• 39.

  2009

  Theodore A. Slotkin; Frederic J. Seidler; Changlong Wu; Emiko A. MacKillop; Karl G. Linden

  Ultraviolet photolysis of chlorpyrifos: Developmental neurotoxicity modeled in PC12 cells

  Environmental Health Perspectives. 2009;117(3):338-343.
  3

• 40.

  2009

  Theodore A. Slotkin; Edward D. Levin; Frederic J. Seidler

  Developmental neurotoxicity of parathion: Progressive effects on serotonergic systems in adolescence and adulthood

  Neurotoxicology and Teratology. 2009;31(1):11-17.
  24

• 41.

  2008

  Olga A. Timofeeva; David Sanders; Kristen Seemann; Liwei Yang; Daniel Hermanson; Sam Regenbogen; Samantha Agoos; Anita Kallepalli; Anit Rastogi; David Braddy; et al.

  Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion

  Brain Research Bulletin. 2008;77(6):404-411.
  26

• 42.

  2008

  Theodore A. Slotkin; Frederic J. Seidler

  Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel

  Toxicology and Applied Pharmacology. 2008;233(2):211-219.
  26

• 43.

  2008

  Gennady A. Buznikov; Lyudmila A. Nikitina; Frederic J. Seidler; Theodore A. Slotkin; Vladimir V. Bezuglov; Ivan Milošević; Lidija Lazarević; Ljubica Rogač; Sabera Ruzdijić; Ljubiša M. Rakić

  Amyloid precursor protein 96-110 and β-amyloid 1-42 elicit developmental anomalies in sea urchin embryos and larvae that are alleviated by neurotransmitter analogs for acetylcholine, serotonin and cannabinoids

  Neurotoxicology and Teratology. 2008;30(6):503-509.
  4

• 44.

  2008

  Theodore A. Slotkin; Frederic J. Seidler; Ian T. Ryde; Joseph Yanai

  Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model

  Neurotoxicology and Teratology. 2008;30(5):433-439.
  11

• 45.

  2008

  Theodore A. Slotkin; Ian T. Ryde; Emiko A. MacKillop; Bethany E. Bodwell; Frederic J. Seidler

  Adolescent nicotine administration changes the responses to nicotine given subsequently in adulthood: Adenylyl cyclase cell signaling in brain regions during nicotine administration and withdrawal, and lasting effects

  Brain Research Bulletin. 2008;76(5):522-530.
  5

• 46.

  2008

  Theodore A. Slotkin; Frederic J. Seidler; Carmen R. Wood; Christopher Lau

  Development of glucocorticoid receptor regulation in the rat forebrain: Implications for adverse effects of glucocorticoids in preterm infants

  Brain Research Bulletin. 2008;76(5):531-535.
  2

• 47.

  2008

  Theodore A. Slotkin; Frederic J. Seidler; Fabio Fumagalli

  Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro

  Brain Research Bulletin. 2008;76(4):424-438.
  29

• 48.

  2008

  Theodore A. Slotkin; Emiko A. MacKillop; Ronald L. Meinick; Kristina A. Thayer; Frederic J. Seidler

  Developmental neurotoxicity of perfluorinated chemicals modeled in vitro

  Environmental Health Perspectives. 2008;116(6):716-722.
  39

• 49.

  2008

  Theodore A. Slotkin; Bethany E. Bodwell; Ian T. Ryde; Frederic J. Seidler

  Adolescent nicotine treatment changes the response of acetylcholine systems to subsequent nicotine administration in adulthood

  Brain Research Bulletin. 2008;76(1-2):152-165.
  11

• 50.

  2008

  Theodore A. Slotkin; Ian T. Ryde; Edward D. Levin; Frederic J. Seidler

  Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: Effects on serotonin systems in adolescence and adulthood

  Brain Research Bulletin. 2008;75(5):640-647.
  31

• 51.

  2008

  Theodore A. Slotkin; Bethany E. Bodwell; Edward D. Levin; Frederic J. Seidler

  Neonatal exposure to low doses of diazinon: Long-term effects of neural cell development and acetylcholine systems

  Environmental Health Perspectives. 2008;116(3):340-348.
  34

• 52.

  2008

  Cindy S. Roegge; Olga A. Timofeeva; Frederic J. Seidler; Theodore A. Slotkin; Edward D. Levin

  Developmental diazinon neurotoxicity in rats: Later effects on emotional response

  Brain Research Bulletin. 2008;75(1):166-172.
  42

• 53.

  2008

  Olga A. Timofeeva; Cindy S. Roegge; Frederic J. Seidler; Theodore A. Slotkin; Edward D. Levin

  Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon

  Neurotoxicology and Teratology. 2008;30(1):38-45.
  43

• 54.

  2008

  Joseph Yanai; Sharon Dotan; Roman Goz; Adi Pinkas; Frederic J. Seidler; Theodore A. Slotkin; Frederic Zimmerman

  Exposure of developing chicks to perfluorooctanoic acid induces defects in prehatch and early posthatch development

  Journal of Toxicology and Environmental Health - Part A: Current Issues. 2008;71(2):131-133.
  11

• 55.

  2008

  Theodore A. Slotkin; Bethany E. Bodwell; Ian T. Ryde; Edward D. Levin; Frederic J. Seidler

  Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood

  Environmental Health Perspectives. 2008;116(10):1308-1314.
  11

• 56.

  2008

  T. Leon Lassiter; Ian T. Ryde; Emiko A. MacKillop; Kathleen K. Brown; Edward D. Levin; Frederic J. Seidler; Theodore A. Slotkin

  Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood

  Environmental Health Perspectives. 2008;116(11):1456-1462.
  27

• 57.

  2007

  Theodore A. Slotkin; Ian T. Ryde; Frederic J. Seidler

  Separate or sequential exposure to nicotine prenatally and in adulthood: Persistent effects on acetylcholine systems in rat brain regions

  Brain Research Bulletin. 2007;74(1-3):91-103.
  23

• 58.

  2007

  Theodore A. Slotkin; Emiko A. MacKillop; Ian T. Ryde; Frederic J. Seidler

  Ameliorating the developmental neurotoxicity of chlorpyrifos: A mechanisms-based approach in PC12 cells

  Environmental Health Perspectives. 2007;115(9):1306-1313.
  28

• 59.

  2007

  Theodore A. Slotkin; Ian T. Ryde; Charlotte A. Tate; Frederic J. Seidler

  Lasting effects of nicotine treatment and withdrawal on serotonergic systems and cell signaling in rat brain regions: Separate or sequential exposure during fetal development and adulthood

  Brain Research Bulletin. 2007;73(4-6):259-272.
  17

• 60.

  2007

  Theodore A. Slotkin; Frederic J. Seidler

  Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats

  Brain Research Bulletin. 2007;73(4-6):301-309.
  19

• 61.

  2007

  Edward D. Levin; Susan Slade Lawrence; Ann Petro; Kofi Horton; Amir H. Rezvani; Frederic J. Seidler; Theodore A. Slotkin

  Adolescent vs. adult-onset nicotine self-administration in male rats: Duration of effect and differential nicotinic receptor correlates

  Neurotoxicology and Teratology. 2007;29(4):458-465.
  52

• 62.

  2007

  M.C. Zerrate; M. Pletnikov; S.L. Connors; D.L. Vargas; F.J. Seidler; A.W. Zimmerman; T.A. Slotkin; Carlos A. Pardo

  Neuroinflammation and behavioral abnormalities after neonatal terbutaline treatment in rats: Implications for autism

  Journal of Pharmacology and Experimental Therapeutics. 2007;322(1):16-22.
  22

• 63.

  2007

  Theodore A. Slotkin; Frederic J. Seidler; Fabio Fumagalli

  Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: Similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily

  Environmental Health Perspectives. 2007;115(6):909-916.
  42

• 64.

  2007

  Theodore A. Slotkin; Frederic J. Seidler

  Comparative developmental neurotoxicity of organophosphates in vivo: Transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems

  Brain Research Bulletin. 2007;72(4-6):232-274.
  89

• 65.

  2007

  Theodore A. Slotkin; Emiko A. MacKillop; Charles L. Rudder; Ian T. Ryde; Charlotte A. Tate; Frederic J. Seidler

  Permanent, sex-selective effects of prenatal or adolescent nicotine exposure, separately or sequentially, in rat brain regions: Indices of cholinergic and serotonergic synaptic function, cell signaling, and neural cell number and size at 6 months of age

  Neuropsychopharmacology. 2007;32(5):1082-1097.
  66

• 66.

  2007

  Theodore A. Slotkin; Frederic J. Seidler

  Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: Critical periods for regional and sex-selective effects

  Reproductive Toxicology. 2007;23(3):421-427.
  39

• 67.

  2007

  Theodore A. Slotkin; Frederic J. Seidler

  A unique role for striatal serotonergic systems in the withdrawal from adolescent nicotine administration

  Neurotoxicology and Teratology. 2007;29(1):10-16.
  16

• 68.

  2007

  Ruth R. Jameson; Frederic J. Seidler; Theodore A. Slotkin

  Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: Chlorpyrifos, chlorpyrifos oxon, and diazinon

  Environmental Health Perspectives. 2007;115(1):65-70.
  39

• 69.

  2007

  Theodore A. Slotkin; Emiko A. MacKillop; Ian T. Ryde; Charlotte A. Tate; Frederic J. Seidler

  Screening for developmental neurotoxicity using PC12 cells: Comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel

  Environmental Health Perspectives. 2007;115(1):93-101.
  59

• 70.

  2006

  Theodore A. Slotkin; Charlotte A. Tate; Mandy M. Cousins; Frederic J. Seidler

  Prenatal nicotine exposure alters the responses to subsequent nicotine administration and withdrawal in adolescence: Serotonin receptors and cell signaling

  Neuropsychopharmacology. 2006;31(11):2462-2475.
  33

• 71.

  2006

  Edward D. Levin; Susan Lawrence; Ann Petro; Kofi Horton; Frederic J. Seidler; Theodore A. Slotkin

  Increased nicotine self-administration following prenatal exposure in female rats

  Pharmacology Biochemistry and Behavior. 2006;85(3):669-674.
  35

• 72.

  2006

  Theodore A. Slotkin; Charlotte A. Tate; Ian T. Ryde; Edward D. Levin; Frederic J. Seidler

  Organophosphate insecticides target the serotonergic system in developing rat brain regions: Disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition

  Environmental Health Perspectives. 2006;114(10):1542-1546.
  47

• 73.

  2006

  Theodore A. Slotkin; Kent E. Pinkerton; Charlotte A. Tate; Frederic J. Seidler

  Alterations of serotonin synaptic proteins in brain regions of neonatal Rhesus monkeys exposed to perinatal environmental tobacco smoke

  Brain Research. 2006;1111(1):30-35.
  19

• 74.

  2006

  Ruth R. Jameson; Frederic J. Seidler; Dan Qiao; Theodore A. Slotkin

  Adverse neurodevelopmental effects of dexamethasone modeled in PC12 cells: Identifying the critical stages and concentration thresholds for the targeting of cell acquisition, differentiation and viability

  Neuropsychopharmacology. 2006;31(8):1647-1658.
  13

• 75.

  2006

  Theodore A. Slotkin; Marisa L. Kreider; Charlotte A. Tate; Frederic J. Seidler

  Critical prenatal and postnatal periods for persistent effects of dexamethasone on serotonergic and dopaminergic systems

  Neuropsychopharmacology. 2006;31(5):904-911.
  31

• 76.

  2006

  Theodore A. Slotkin; Edward D. Levin; Frederic J. Seidler

  Comparative developmental neurotoxicity of organophosphate insecticides: Effects on brain development are separable from systemic toxicity

  Environmental Health Perspectives. 2006;114(5):746-751.
  86

• 77.

  2006

  Ruth R. Jameson; Frederic J. Seidler; Dan Qiao; Theodore A. Slotkin

  Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: Critical stages targeting differentiation PC12 cells

  Environmental Health Perspectives. 2006;114(5):667-672.
  42

• 78.

  2006

  Theodore A. Slotkin; Frederic J. Seidler

  Anomalous regulation of β-adrenoceptor signaling in brain regions of the newborn rat

  Brain Research. 2006;1077(1):54-58.
  3

• 79.

  2006

  Theodore A. Slotkin; Frederic J. Seidler

  Cholinergic receptor subtypes in the olfactory bulbectomy model of depression

  Brain Research Bulletin. 2006;68(5):341-345.
  10

• 80.

  2006

  Theodore A. Slotkin; Kent E. Pinkerton; Frederic J. Seidler

  Perinatal environmental tobacco smoke exposure in rhesus monkeys: Critical periods and regional selectivity for effects on brain cell development and lipid peroxidation

  Environmental Health Perspectives. 2006;114(1):34-39.
  23

• 81.

  2006

  Marisa L. Kreider; Charlotte A. Tate; Mandy M. Cousins; Colleen A. Oliver; Frederic J. Seidler; Theodore A. Slotkin

  Lasting effects of developmental dexamethasone treatment on neural cell number and size, synaptic activity, and cell signaling: Critical periods of vulnerability, dose-effect relationships, regional targets, and sex selectivity

  Neuropsychopharmacology. 2006;31(1):12-35.
  33

• 82.

  2005

  Theodore A. Slotkin; Charlotte A. Tate; Mandy M. Cousins; Frederic J. Seidler

  Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination

  Developmental Brain Research. 2005;160(2):219-230.
  6

• 83.

  2005

  Marisa L. Kreider; Justin E. Aldridge; Mandy M. Cousins; Colleen A. Oliver; Frederic J. Seidler; Theodore A. Slotkin

  Disruption of rat forebrain development by glucocorticoids: Critical perinatal periods for effects on neural cell acquisition and on cell signaling cascades mediating noradrenergic and cholinergic neurotransmitter/neurotrophic responses

  Neuropsychopharmacology. 2005;30(10):1841-1855.
  18

• 84.

  2005

  Theodore A. Slotkin; Kathleen K. Brown; Frederic J. Seidler

  Developmental exposures of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood

  Environmental Health Perspectives. 2005;113(10):1291-1294.
  26

• 85.

  2005

  Marisa L. Kreider; Edward D. Levin; Frederic J. Seidler; Theodore A. Slotkin

  Gestational dexamethasone treatment elicits sex-dependent alterations in locomotor activity, reward-based memory and hippocampal cholinergic function in adolescent and adult rats

  Neuropsychopharmacology. 2005;30(9):1617-1623.
  22

• 86.

  2005

  Theodore A. Slotkin; Frederic J. Seidler

  The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent

  Developmental Brain Research. 2005;158(1-2):115-119.
  43

• 87.

  2005

  Justin E. Aldridge; Armando Meyer; Frederic J. Seidler; Theodore A. Slotkin

  Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure

  Environmental Health Perspectives. 2005;113(8):1027-1031.
  68

• 88.

  2005

  Dan Qiao; Frederic J. Seidler; Theodore A. Slotkin

  Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos

  Toxicology and Applied Pharmacology. 2005;206(1):17-26.
  88

• 89.

  2005

  Theodore A. Slotkin; Colleen A. Oliver; Frederic J. Seidler

  Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination

  Developmental Brain Research. 2005;157(2):172-180.
  35

• 90.

  2005

  Stephanie J. Garcia; Frederic J. Seidler; Theodore A. Slotkin

  Developmental neurotoxicity of chlorpyrifos: Targeting glial cells

  Environmental Toxicology and Pharmacology. 2005;19(3):455-461.
  14

• 91.

  2005

  Justin E. Aldridge; Edward D. Levin; Frederic J. Seidler; Theodore A. Slotkin

  Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression

  Environmental Health Perspectives. 2005;113(5):527-531.
  91

• 92.

  2005

  Tara Sankar Roy; Vikram Sharma; Frederic J. Seidler; Theodore A. Slotkin

  Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats

  Developmental Brain Research. 2005;155(1):71-80.
  33

• 93.

  2005

  Armando Meyer; Frederic J. Seidler; Justin E. Aldridge; Theodore A. Slotkin

  Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos

  Toxicology and Applied Pharmacology. 2005;203(2):154-166.
  24

• 94.

  2005

  Justin E. Aldridge; Armando Meyer; Frederic J. Seidler; Theodore A. Slotkin

  Developmental exposure to terbutaline and chlorpyrifos: Pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions

  Toxicology and Applied Pharmacology. 2005;203(2):132-144.
  31

• 95.

  2005

  Yael Abreu-Villaça; Frederic J. Seidler; Dan Qiao; Theodore A. Slotkin

  Modeling the developmental neurotoxicity of nicotine in vitro: Cell acquisition, growth and viability in PC12 cells

  Developmental Brain Research. 2005;154(2):239-246.
  16

• 96.

  2005

  Theodore A. Slotkin; Mandy M. Cousins; Charlotte A. Tate; Frederic J. Seidler

  Serotonergic cell signaling in an animal model of aging and depression: Olfactory bulbectomy elicits different adaptations in brain regions of young adult vs aging

  Neuropsychopharmacology. 2005;30(1):52-57.
  23

• 97.

  2005

  Avital Beer; Theodore A. Slotkin; Frederic J. Seidler; Justin E. Aldridge; Joseph Yanai

  Nicotine therapy in adulthood reverses the synaptic and behavioral deficits elicited by prenatal exposure to phenobarbital

  Neuropsychopharmacology. 2005;30(1):156-165.
  19

• 98.

  2005

  Theodore A. Slotkin; Frederic J. Seidler; Dan Qiao; Justin E. Aldridge; Charlotte A. Tate; Mandy M. Cousins; Becky J. Proskocil; Harmanjatinder S. Sekhon; Jennifer A. Clark; Stacie L. Lupo; et al.

  Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or Vitamin C: Neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of Rhesus monkeys

  Neuropsychopharmacology. 2005;30(1):129-144.
  44

• 99.

  2004

  Theodore A. Slotkin; Mandy M. Cousins; Frederic J. Seidler

  Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS α7 nicotinic acetylcholine receptors

  Brain Research. 2004;1030(1):159-163.
  19

• 100.

  2004

  Theodore A. Slotkin; Matthew C. Southard; Stacey J. Adam; Mandy M. Cousins; Frederic J. Seidler

  α7 Nicotinic acetylcholine receptors targeted by cholinergic developmental neurotoxicants: Nicotine and chlorpyrifos

  Brain Research Bulletin. 2004;64(3):227-235.
  17

• 101.

  2004

  Marisa L. Kreider; Frederic J. Seidler; Mandy M. Cousins; Charlotte A. Tate; Theodore A. Slotkin

  Transiently overexpressed α ₂-adrenoceptors and their control of DNA synthesis in the developing brain

  Developmental Brain Research. 2004;152(2):233-239.
  6

• 102.

  2004

  Yael Abreu-Villaça; Frederic J. Seidler; Theodore A. Slotkin

  Does prenatal nicotine exposure sensitize the brain to nicotine-induced neurotoxicity in adolescence?

  Neuropsychopharmacology. 2004;29(8):1440-1450.
  45

• 103.

  2004

  Yael Abreu-Villaça; Frederic J. Seidler; Charlotte A. Tate; Mandy M. Cousins; Theodore A. Slotkin

  Prenatal nicotine exposure alters the response to nicotine administration in adolescence: Effects on cholinergic systems during exposure and withdrawal

  Neuropsychopharmacology. 2004;29(5):879-890.
  57

• 104.

  2004

  Melissa C. Rhodes; Frederic J. Seidler; Dan Qiao; Charlotte A. Tate; Mandy M. Cousins; Theodore A. Slotkin

  Does pharmacotherapy for preterm labor sensitize the developing brain to environmental neurotoxicants? Cellular and synaptic effects of sequential exposure to terbutaline and chlorpyrifos in neonatal rats

  Toxicology and Applied Pharmacology. 2004;195(2):203-217.
  26

• 105.

  2004

  Armando Meyer; Frederic J. Seidler; Justin E. Aldridge; Charlotte A. Tate; Mandy M. Cousins; Theodore A. Slotkin

  Critical periods for Chlorpyrifos-induced developmental neurotoxicity: Alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure

  Environmental Health Perspectives. 2004;112(3):295-301.
  34

• 106.

  2004

  Tara Sankar Roy; Frederic J. Seidler; Theodore A. Slotkin

  Morphologic effects of subtoxic neonatal chlorpyrifos exposure in developing rat brain: Regionally selective alterations in neurons and glia

  Developmental Brain Research. 2004;148(2):197-206.
  28

• 107.

  2004

  Armando Meyer; Frederic J. Seidler; Theodore A. Slotkin

  Developmental effects of chlorpyrifos extend beyond neurotoxicity: Critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling

  Environmental Health Perspectives. 2004;112(2):170-178.
  27

• 108.

  2004

  Justin E. Aldridge; Frederic J. Seidler; Theodore A. Slotkin

  Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: Critical periods and regional selectivity for effects on the serotinin transporter, receptor subtypes, and cell signaling

  Environmental Health Perspectives. 2004;112(2):148-155.
  79

• 109.

  2004

  Melissa C. Rhodes; Frederic J. Seidler; Ali Abdel-Rahman; Charlotte A. Tate; Abraham Nyska; Heather L. Rincavage; Theodore A. Slotkin

  Terbutaline Is a Developmental Neurotoxicant: Effects on Neuroproteins and Morphology in Cerebellum, Hippocampus, and Somatosensory Cortex

  Journal of Pharmacology and Experimental Therapeutics. 2004;308(2):529-537.
  35

• 110.

  2004

  Dan Qiao; Frederic J. Seidler; Yael Abreu-Villaça; Charlotte A. Tate; Mandy M. Cousins; Theodore A. Slotkin

  Chlorpyrifos exposure during neurulation: Cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood

  Developmental Brain Research. 2004;148(1):43-52.
  44

• 111.

  2004

  Marisa L. Kreider; Frederic J. Seidler; Theodore A. Slotkin

  β-Adrenoceptor modulation of transiently overexpressed α ₂-adrenoceptors in brain and peripheral tissues: Cellular mechanisms underlying the developmental toxicity of terbutaline

  Brain Research Bulletin. 2004;62(4):305-314.
  7

• 112.

  2004

  Laura M. Icenogle; N. Channelle Christopher; W. Paul Blackwelder; D. Patrick Caldwell; Dan Qiao; Frederic J. Seidler; Theodore A. Slotkin; Edward D. Levin

  Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation

  Neurotoxicology and Teratology. 2004;26(1):95-101.
  60

• 113.

  2003

  Dan Qiao; Frederic J. Seidler; Jonathan D. Violin; Theodore A. Slotkin

  Nicotine is a developmental neurotoxicant and neuroprotectant: Stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos

  Developmental Brain Research. 2003;147(1-2):183-190.
  34

• 114.

  2003

  Hernan A. Navarro; Patricia V. Basta; Frederic J. Seidler; Theodore A. Slotkin

  Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: Critical periods, patterns of exposure, dose thresholds

  Nicotine and Tobacco Research. 2003;5(6):859-868.
  6

• 115.

  2003

  Armando Meyer; Frederic J. Seidler; Mandy M. Cousins; Theodore A. Slotkin

  Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: When is adenylyl cyclase a target?

  Environmental Health Perspectives. 2003;111(16):1871-1876.
  23

• 116.

  2003

  Zengjun Xu; Frederic J. Seidler; Charlotte A. Tate; Stephanie J. Garcia; William Slikker Jr.; Theodore A. Slotkin

  Sex-selective hippocampal alterations after adolescent nicotine administration: Effects on neurospecific proteins

  Nicotine and Tobacco Research. 2003;5(6):955-960.
  21

• 117.

  2003

  Melissa C. Rhodes; Abraham Nyska; Frederic J. Seidler; Theodore A. Slotkin

  Does Terbutaline Damage the Developing Heart?

  Birth Defects Research Part B - Developmental and Reproductive Toxicology. 2003;68(6):449-455.
  1

• 118.

  2003

  Yael Abreu-Villaça; Frederic J. Seidler; Dan Qiao; Charlotte A. Tate; Mandy M. Cousins; Indira Thillai; Theodore A. Slotkin

  Short-Term Adolescent Nicotine Exposure has Immediate and Persistent Effects on Cholinergic Systems: Critical Periods, Patterns of Exposure, Dose Thresholds

  Neuropsychopharmacology. 2003;28(11):1935-1949.
  75

• 119.

  2003

  Dan Qiao; Lyudmila A. Nikitina; Gennady A. Buznikov; Jean M. Lauder; Frederic J. Seidler; Theodore A. Slotkin

  The sea urchin embryo as a model for mammalian developmental neurotoxicity: Ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity

  Environmental Health Perspectives. 2003;111(14):1730-1735.
  14

• 120.

  2003

  Justin E. Aldridge; Frederick J. Seidler; Armando Meyer; Indira Thillai; Theodore A. Slotkin

  Serotonergic systems targeted by developmental exposure to chlorpyrifos: Effects during different critical periods

  Environmental Health Perspectives. 2003;111(14):1736-1743.
  67

• 121.

  2003

  Yael Abreu-Villaça; Frederic J. Seidler; Theodore A. Slotkin

  Impact of adolescent nicotine exposure on adenylyl cyclase-mediated cell signaling: Enzyme induction, neurotransmitter-specific effects, regional selectivities, and the role of withdrawal

  Brain Research. 2003;988(1-2):164-172.
  37

• 122.

  2003

  Theodore A. Slotkin; Frederic J. Seidler; Joseph Yanai

  Heroin neuroteratogenicity: Delayed-onset deficits in catecholaminergic synaptic activity

  Brain Research. 2003;984(1-2):189-197.
  2

• 123.

  2003

  Theodore A. Slotkin; Brian D. Freibaum; Charlotte A. Tate; Indira Thillai; Sherry A. Ferguson; Amy M. Cada; Frederic J. Seidler

  Long-lasting CNS effects of a short-term chemical knockout of ornithine decarboxylase during development: Nicotinic cholinergic receptor upregulation and subtle macromolecular changes in adulthood

  Brain Research. 2003;981(1-2):118-125.
  11

• 124.

  2003

  Yael Abreu-Villaça; Frederic J. Seidler; Charlotte A. Tate; Theodore A. Slotkin

  Nicotine is a neurotoxin in the adolescent brain: Critical periods, patterns of exposure, regional selectivity, and dose thresholds for macromolecular alterations

  Brain Research. 2003;979(1-2):114-128.
  63

• 125.

  2003

  Theodore A. Slotkin; J. Todd Auman; Frederic J. Seidler

  Ontogenesis of β-adrenoceptor signaling: Implications for perinatal physiology and for fetal effects of tocolytic drugs

  Journal of Pharmacology and Experimental Therapeutics. 2003;306(1):1-7.
  41

• 126.

  2003

  Dan Qiao; Frederic J. Seidler; Charlotte A. Tate; Mandy M. Cousins; Theodore A. Slotkin

  Fetal chlorpyrifos exposure: Adverse effects on brain cell development and cholinergic emerge postnatally and continue into adolescence and adulthood

  Environmental Health Perspectives. 2003;111(4):536-544.
  82

• 127.

  2003

  Stephanie J. Garcia; Frederic J. Seidler; Theodore A. Slotkin

  Developmental neurotoxicity elicited by prenatal or postnatal chlorpyrifos exposure: Effects on neurospecific proteins indicate changing vulnerabilities

  Environmental Health Perspectives. 2003;111(3):297-303.
  55

• 128.

  2003

  Melissa C. Garofolo; Frederic J. Seidler; Mandy M. Cousins; Charlotte A. Tate; Dan Qiao; Theodore A. Slotkin

  Developmental toxicity of terbutaline: Critical periods for sex-selective effects on macromolecules and DNA synthesis in rat brain, heart, and liver

  Brain Research Bulletin. 2003;59(4):319-329.
  18

• 129.

  2003

  Kristina Dam; Frederic J. Seidler; Theodore A. Slotkin

  Transcriptional biomarkers distinguish between vulnerable periods for developmental neurotoxicity of chlorpyrifos: Implications for toxicogenomics

  Brain Research Bulletin. 2003;59(4):261-265.
  28

• 130.

  2002

  J.T. Auman; F.J. Seidler; T.A. Slotkin

  β-adrenoceptor control of g protein function in the neonate: Determinant of desensitization or sensitization

  American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 2002;283(5 52-5):R1236-R1244.
  8

• 131.

  2002

  Edward D. Levin; Nii Addy; Avanti Baruah; Alana Elias; N. Channelle Christopher; Frederic J. Seidler; Theodore A. Slotkin

  Prenatal chlorpyrifos exposure in rats causes persistent behavioral alterations

  Neurotoxicology and Teratology. 2002;24(6):733-741.
  111

• 132.

  2002

  Dan Qiao; Frederic J. Seidler; Stephanie Padilla; Theodoro A. Slotkin

  Developmental neurotoxicity of chlorpyrifos: What is the vulnerable period?

  Environmental Health Perspectives. 2002;110(11):1097-1103.
  65

• 133.

  2002

  Z Xu; F.J Seidler; M.M Cousins; W Slikker Jr.; T.A Slotkin

  Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase

  Brain Research. 2002;951(2):280-292.
  52

• 134.

  2002

  Stephanie J Garcia; Frederic J Seidler; Dan Qiao; Theodore A Slotkin

  Chlorpyrifos targets developing glia: Effects on glial fibrillary acidic protein

  Developmental Brain Research. 2002;133(2):151-161.
  62

• 135.

  2002

  T.A. Slotkin; C.A. Tate; M.M. Cousins; F.J. Seidler

  Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure

  Developmental Brain Research. 2002;133(2):163-173.
  75

• 136.

  2002

  T.A. Slotkin; K.E. Pinkerton; J.T. Auman; D. Qiao; F.J. Seidler

  Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain

  Developmental Brain Research. 2002;133(2):175-179.
  43

• 137.

  2002

  M.C. Garofolo; F.J. Seidler; J.T. Auman; T.A. Slotkin

  β-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart

  American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 2002;282(5 51-5):R1356-R1363.
  23

• 138.

  2002

  Tara Sankar Roy; Frederic J. Seidler; Theodore A. Slotkin

  Prenatal nicotine exposure evokes alterations of cell structure in hippocampus and somatosensory cortex

  Journal of Pharmacology and Experimental Therapeutics. 2002;300(1):124-133.
  77

• 139.

  2002

  J.T. Auman; F.J. Seidler; C.A. Tate; T.A. Slotkin

  Are developing β-adrenoceptors able to desensitize? Acute and chronic effects of β-agonists in neonatal heart and liver

  American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 2002;283(1 52-1):R205-R217.
  13

• 140.

  2001

  Theodore A. Slotkin; Frederic J. Seidler; Joseph Yanai

  Heroin neuroteratogenicity: Targeting adenylyl cyclase as an underlying biochemical mechanism

  Developmental Brain Research. 2001;132(1):69-79.
  13

• 141.

  2001

  T.A. Slotkin; C.A. Tate; M.M. Cousins; F.J. Seidler

  β-Adrenoceptor signaling in the developing brain: Sensitization or desensitization in response to terbutaline

  Developmental Brain Research. 2001;131(1-2):113-125.
  30

• 142.

  2001

  H.A. Navarro; P.V. Basta; F.J. Seidler; T.A. Slotkin

  Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: A neural effect?

  Developmental Brain Research. 2001;130(2):249-252.
  21

• 143.

  2001

  H.A. Navarro; P.V. Basta; F.J. Seidler; T.A. Slotkin

  Adolescent nicotine: Deficits in immune function

  Developmental Brain Research. 2001;130(2):253-256.
  8

• 144.

  2001

  Z. Xu; F.J. Seidler; S.F. Ali; Jr. Slikker; T.A. Slotkin

  Fetal and adolescent nicotine administration: Effects on CNS serotonergic systems

  Brain Research. 2001;914(1-2):166-178.
  117

• 145.

  2001

  E.D. Levin; N. Addy; A. Nakajima; N.C. Christopher; F.J. Seidler; T.A. Slotkin

  Persistent behavioral consequences of neonatal chlorpyrifos exposure in rats

  Developmental Brain Research. 2001;130(1):83-89.
  122

• 146.

  2001

  K.W. Raines; F.J. Seidler; T.A. Slotkin

  Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos

  Developmental Brain Research. 2001;130(1):65-72.
  36

• 147.

  2001

  T.A. Slotkin; M.M. Cousins; C.A. Tate; F.J. Seidler

  Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure

  Brain Research. 2001;902(2):229-243.
  90

• 148.

  2001

  T.A. Slotkin; K.E. Pinkerton; M.C. Garofolo; J.T. Auman; E.C. McCook; F.J. Seidler

  Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats

  Brain Research. 2001;898(1):73-81.
  25

• 149.

  2001

  Jennifer A. Trauth; Frederic J. Seidler; Syed F. Ali; Theodore A. Slotkin

  Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function

  Brain Research. 2001;892(2):269-280.
  84

• 150.

  2001

  S.J. Garcia; F.J. Seidler; T.L. Crumpton; T.A. Slotkin

  Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells

  Brain Research. 2001;891(1-2):54-68.
  63

• 151.

  2001

  J.T. Auman; F.J. Seidler; C.A. Tate; T.A. Slotkin

  β-adrenoceptor-mediated cell signaling in the neonatal heart and liver: Responses to terbutaline

  American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 2001;281(6 50-6):R1895-R1901.
  20

• 152.

  2001

  Dan Qiao; Frederic J. Seidler; Theodore A. Slotkin

  Developmental neurotoxicity of chlorpyrifos modeled in vitro: Comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells

  Environmental Health Perspectives. 2001;109(9):909-913.
  90

• 153.

  2001

  J.T. Auman; F.J. Seidler; T.A. Slotkin

  Regulation of fetal cardiac and hepatic β-adrenoceptors and adenylyl cyclase signaling: Terbutaline effects

  American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 2001;281(4 50-4):R1079-R1089.
  32

• 154.

  2001

  T.L. Crumpton; F.J. Seidler; T.A. Slotkin

  Generation of reactive oxygen species by xanthine derivatives in MDA-MB-231 human breast cancer cells

  Breast Cancer Research and Treatment. 2001;66(2):143-146.
  1

• 155.

  2000

  T.A Slotkin; S.A Ferguson; A.M Cada; E.C McCook; F.J Seidler

  Neonatal polyamine depletion by α-difluoromethylornithine: Effects on adenylyl cyclase cell signaling are separable from effects on brain region growth

  Brain Research. 2000;887(1):16-22.
  11

• 156.

  2000

  T.A. Slotkin; K.E. Pinkerton; F.J. Seidler

  Perinatal exposure to environmental tobacco smoke alters cell signaling in a primate model: Autonomic receptors and the control of adenylyl cyclase activity in heart and lung

  Developmental Brain Research. 2000;124(1-2):53-58.
  13

• 157.

  2000

  Theodore A. Slotkin; Frederic J. Seidler; James C. Ritchie

  Regional differences in brain monoamine oxidase subtypes in an animal model of geriatric depression: Effects of olfactory bulbectomy in young versus aged rats

  Brain Research. 2000;882(1-2):149-154.
  9

• 158.

  2000

  J.A. Trauth; F.J. Seidler; T.A. Slotkin

  Persistent and delayed behavioral changes after nicotine treatment in adolescent rats

  Brain Research. 2000;880(1-2):167-172.
  69

• 159.

  2000

  T.A. Slotkin; F.J. Seidler; S.F. Ali

  Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions

  Brain Research. 2000;879(1-2):163-173.
  23

• 160.

  2000

  F.A. Chow; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Adolescent nicotine exposure alters cardiac autonomic responsiveness: β-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase

  Brain Research. 2000;878(1-2):119-126.
  16

• 161.

  2000

  Jennifer A. Trauth; Everett C. McCook; Frederic J. Seidler; Theodore A. Slotkin

  Modeling adolescent nicotine exposure: Effects on cholinergic systems in rat brain regions

  Brain Research. 2000;873(1):18-25.
  55

• 162.

  2000

  K. Dam; F.J. Seidler; T.A. Slotkin

  Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity

  Developmental Brain Research. 2000;121(2):179-187.
  115

• 163.

  2000

  T.L. Crumpton; F.J. Seidler; T.A. Slotkin

  Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos?

  Developmental Brain Research. 2000;121(2):189-195.
  67

• 164.

  2000

  Jennifer A. Trauth; Frederic J. Seidler; Theodore A. Slotkin

  An animal model of adolescent nicotine exposure: Effects on gene expression and macromolecular constituents in rat brain regions

  Brain Research. 2000;867(1-2):29-39.
  123

• 165.

  2000

  J.T. Auman; F.J. Seidler; T.A. Slotkin

  Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: Implications for neurotoxicity

  Developmental Brain Research. 2000;121(1):19-27.
  46

• 166.

  2000

  J.L. Zeiders; F.J. Seidler; T.A. Slotkin

  Ontogeny of G-protein expression: Control by β-adrenoceptors

  Developmental Brain Research. 2000;120(2):125-134.
  17

• 167.

  2000

  T.L. Crumpton; F.J. Seidler; T.A. Slotkin

  Developmental neurotoxicity of chlorpyrifos in vivo and in vitro: Effects on nuclear transcription factors involved in cell replication and differentiation

  Brain Research. 2000;857(1-2):87-98.
  100

• 168.

  2000

  Theodore A. Slotkin; Jian Zhang; Ria Dancel; Stephanie J. Garcia; Carrie Willis; Frederic J. Seidler

  β-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells

  Breast Cancer Research and Treatment. 2000;60(2):153-166.
  44

• 169.

  2000

  T.A. Slotkin; F.J. Seidler

  Antimitotic and cytotoxic effects of theophylline in MDA-MB-231 human breast cancer cells

  Breast Cancer Research and Treatment. 2000;64(3):259-267.
  4

• 170.

  1999

  J.A. Trauth; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Adolescent nicotine exposure causes persistent upregulation of nicotinic cholinergic receptors in rat brain regions

  Brain Research. 1999;851(1-2):9-19.
  144

• 171.

  1999

  Kristina Dam; Frederic J. Seidler; Theodore A. Slotkin

  Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes

  Developmental Brain Research. 1999;118(1-2):129-133.
  33

• 172.

  1999

  J.L. Zeiders; F.J. Seidler; T.A. Slotkin

  Agonist-induced sensitization of β-adrenoceptor signaling in neonatal rat heart: Expression and catalytic activity of adenylyl cyclase

  Journal of Pharmacology and Experimental Therapeutics. 1999;291(2):503-510.
  39

• 173.

  1999

  Kristina Dam; Stephanie J. Garcia; Frederic J. Seidler; Theodore A. Slotkin

  Neonatal chlorpyrifos exposure alters synaptic development and neuronal activity in cholinergic and catecholaminergic pathways

  Developmental Brain Research. 1999;116(1):9-20.
  112

• 174.

  1999

  Theodore A. Slotkin; Diane B. Miller; Fabio Fumagalli; Everett C. McCook; Jian Zhang; Garth Bissette; Frederic J. Seidler

  Modeling geriatric depression in animals: Biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats

  Journal of Pharmacology and Experimental Therapeutics. 1999;289(1):334-345.
  46

• 175.

  1999

  Theodore A. Slotkin; Tiffany A. Epps; Maranda L. Stenger; Kevin J. Sawyer; Frederic J. Seidler

  Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: Implications for hypoxia tolerance and perinatal mortality

  Developmental Brain Research. 1999;113(1-2):1-12.
  83

• 176.

  1999

  J.L. Zeiders; F.J. Seidler; G. Iaccarino; W.J. Koch; T.A. Slotkin

  Ontogeny of cardiac β-adrenoceptor desensitization mechanisms: Agonist treatment enhances receptor/G-protein transduction rather than eliciting uncoupling

  Journal of Molecular and Cellular Cardiology. 1999;31(2):413-423.
  35

• 177.

  1999

  Jennifer A. Trauth; Frederic J. Seidler; Everett C. McCook; Theodore A. Slotkin

  Persistent c-fos induction by nicotine in developing rat brain regions: Interaction with hypoxia

  Pediatric Research. 1999;45(1):38-45.
  24

• 178.

  1998

  T.A. Slotkin; J. Zhang; E.C. McCook; F.J. Seidler

  Glucocorticoid administration alters nuclear transcription factors in fetal rat brain: Implications for the use of antenatal steroids

  Developmental Brain Research. 1998;111(1):11-24.
  41

• 179.

  1998

  Theodore A. Slotkin; Frederic J. Seidler; James C. Ritchie

  Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: Therapeutic implications

  Brain Research Bulletin. 1998;47(4):345-348.
  16

• 180.

  1998

  Theodore A. Slotkin; Jian Zhang; Everett C. McCook; Frederic J. Seidler

  Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats

  Brain Research. 1998;800(2):236-244.
  7

• 181.

  1998

  T.S. Roy; J.E. Andrews; F.J. Seidler; T.A. Slotkin

  Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos

  Teratology. 1998;58(2):62-68.
  78

• 182.

  1998

  X. Song; J.D. Violin; F.J. Seidler; T.A. Slotkin

  Modeling the developmental neurotoxicity of chlorpyrifos in vitro: Macromolecule synthesis in PC12 cells

  Toxicology and Applied Pharmacology. 1998;151(1):182-191.
  109

• 183.

  1998

  K. Dam; F.J. Seidler; T.A. Slotkin

  Developmental neurotoxicity of chlorpyrifos: Delayed targeting of DNA synthesis after repeated administration

  Developmental Brain Research. 1998;108(1-2):39-45.
  84

• 184.

  1998

  J.L. Zeiders; F.J. Seidler; T.A. Slotkin

  Unique mechanisms of β-adrenoceptor sensitization and desensitization during development

  FASEB Journal. 1998;12(4):A444.
  0

• 185.

  1998

  Tong H. Lee; Kyle R. Gee; Everett H. Ellinwood; Frederic J. Seidler

  Altered cocaine potency in the nucleus accumbens following 7-day withdrawal from intermittent but not continuous treatment: Voltammetric assessment of dopamine uptake in the rat

  Psychopharmacology. 1998;137(3):303-310.
  13

• 186.

  1998

  D.E. Johnson; F.J. Seidler; T.A. Slotkin

  Early biochemical detection of delayed neurotoxicity resulting from developmental exposure to chlorpyrifos

  Brain Research Bulletin. 1998;45(2):143-147.
  66

• 187.

  1997

  K.E. McGrath; F.J. Seidler; T.A. Slotkin

  Convergent control of serotonin transporter expression by glucocorticoids and cocaine in fetal and neonatal rat brain

  Developmental Brain Research. 1997;104(1-2):209-213.
  10

• 188.

  1997

  X. Song; F.J. Seidler; J.L. Saleh; J. Zhang; S. Padilla; T.A. Slotkin

  Cellular mechanisms for developmental toxicity of chlorpyrifos: Targeting the adenylyl cyclase signaling cascade

  Toxicology and Applied Pharmacology. 1997;145(1):158-174.
  162

• 189.

  1997

  J.P. Tan; F.J. Seidler; D.A. Schwinn; S.O. Page; T.A. Slotkin

  A critical period for the role of thyroid hormone in development of renal α-adrenergic receptors

  Pediatric Research. 1997;42(1):93-102.
  5

• 190.

  1997

  T.A. Slotkin; X.-F. Wang; H.S. Symonds; F.J. Seidler

  Expression of mRNAs coding for the transforming growth factor-β receptors in brain regions of euthyroid and hypothyroid neonatal rats and in adult brain

  Developmental Brain Research. 1997;99(1):61-65.
  13

• 191.

  1997

  T.A. Slotkin; J.L. Saleh; E.C. McCook; F.J. Seidler

  Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally: Implications for perinatal morbidity and mortality, and for sudden infant death syndrome

  Teratology. 1997;55(3):177-184.
  75

• 192.

  1997

  S.E. Renick; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat: Effects of sympathectomy

  Pediatric Research. 1997;41(3):359-363.
  13

• 193.

  1997

  J.L. Zeiders; F.J. Seidler; T.A. Slotkin

  Ontogeny of regulatory mechanisms for β-adrenoceptor control of rat cardiac adenylyl cyclase: Targeting of G-proteins and the cyclase catalytic subunit

  Journal of Molecular and Cellular Cardiology. 1997;29(2):603-615.
  43

• 194.

  1997

  T.A. Slotkin; E.C. McCook; J.C. Ritchie; B.J. Carroll; F.J. Seidler

  Serotonin transporter expression in rat brain regions and blood platelets: Aging and glucocorticoid effects

  Biological Psychiatry. 1997;41(2):172-183.
  51

• 195.

  1997

  C.G. Campbell; F.J. Seidler; T.A. Slotkin

  Chlorpyrifos interferes with cell development in rat brain regions

  Brain Research Bulletin. 1997;43(2):179-189.
  122

• 196.

  1996

  T.A. Slotkin; J.L. Saleh; J. Zhang; F.J. Seidler

  Ontogeny of β-adrenoceptor/adenylyl cyclase desensitization mechanisms: The role of neonatal innervation

  Brain Research. 1996;742(1-2):317-328.
  15

• 197.

  1996

  T.A. Slotkin; L. Thai; E.C. McCook; J.L. Saleh; J. Zhang; F.J. Seidler

  Aging and glucocorticoids: Effects on cell signaling mediated through adenylyl cyclase

  Journal of Pharmacology and Experimental Therapeutics. 1996;279(2):478-491.
  10

• 198.

  1996

  Theodore A. Slotkin; Everett C. McCook; James C. Ritchie; Frederic J. Seidler

  Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? An animal model

  Biological Psychiatry. 1996;40(7):576-584.
  22

• 199.

  1996

  Tong H. Lee; Kyle R. Gee; Everett H. Ellinwood; Frederic J. Seidler

  Combining 'caged-dopamine' photolysis with fast-scan cyclic voltammetry to assess dopamine clearance and release autoinhibition in vitro

  Journal of Neuroscience Methods. 1996;67(2):221-231.
  13

• 200.

  1996

  T.A. Slotkin; G.A. Barnes; E.C. McCook; F.J. Seidler

  Programming of brainstem serotonin transporter development by prenatal glucocorticoids

  Developmental Brain Research. 1996;93(1-2):155-161.
  59

• 201.

  1996

  F. Fumagalli; S.R. Jones; M.G. Caron; F.J. Seidler; T.A. Slotkin

  Expression of mRNA coding for the serotonin transporter in aged vs. young rat brain: Differential effects of glucocorticoids

  Brain Research. 1996;719(1-2):225-228.
  39

• 202.

  1996

  L.D. Metz; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Cardiac α-adrenergic receptor expression is regulated by thyroid hormone during a critical developmental period

  Journal of Molecular and Cellular Cardiology. 1996;28(5):1033-1044.
  13

• 203.

  1996

  L. Thai; J.M. Galluzzo; E.C. Mccook; F.J. Seidler; T.A. Slotkin

  Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: Agonists evoke supersensitivity accompanied by failure of receptor down-regulation

  Pediatric Research. 1996;39(4 I):697-707.
  18

• 204.

  1996

  T.A. Slotkin; C. Lau; S.E. Lappi; F.J. Seidler

  Can intracellular signalling pathways predict developmental abnormalities? Sensitivity of the adenylyl cyclase/c-fos protooncogene cascade to β-adrenergic agonists and glucocorticoids in foetal rat

  Biomarkers. 1996;1(2):115-122.
  7

• 205.

  1996

  G. Bissette; F.J. Seidler; C.B. Nemeroff; T.A. Slotkin

  High affinity choline transporter status in Alzheimer's disease tissue from rapid autopsy

  Annals of the New York Academy of Sciences. 1996;777:197-204.
  25

• 206.

  1995

  J.P. Wagner; F.J. Seidler; S.E. Lappi; E.C. McCook; T.A. Slotkin

  Role of presynaptic input in the ontogeny of adrenergic cell signaling in rat brain: Beta receptors, adenylate cyclase and c-fos protooncogene expression

  Journal of Pharmacology and Experimental Therapeutics. 1995;273(1):415-426.
  24

• 207.

  1995

  F.J. Seidler; S.W. Temple; E.C. McCook; T.A. Slotkin

  Cocaine inhibits central noradrenergic and dopaminergic activity during the critical developmental period in which catecholamines influence cell development

  Developmental Brain Research. 1995;85(1):48-53.
  36

• 208.

  1995

  T.A. Slotkin; S.E. Lappi; F.J. Seidler

  β-Adrenergic control of c-fos expression in fetal and neonatal rat tissues: Relationship to cell differentiation and teratogenesis

  Toxicology and Applied Pharmacology. 1995;133(2):188-195.
  19

• 209.

  1995

  C.E. Giannuzzi; F.J. Seidler; T.A. Slotkin

  β-Adrenoceptor control of cardiac adenylyl cyclase during development: Agonist pretreatment in the neonate uniquely caused heterologous sensitization, not desensitization

  Brain Research. 1995;694(1-2):271-278.
  27

• 210.

  1995

  G.S. Rao; F.J. Seidler; T.A. Slotkin

  Modulation of hepatic adrenergic receptor ontogeny by thyroid hormone

  Research Communications in Molecular Pathology and Pharmacology. 1995;87(1):27-42.
  5

• 211.

  1995

  T.A. Slotkin; S.E. Lappi; E.C. McCook; B.A. Lorber; F.J. Seidler

  Loss of neonatal hypoxia tolerance after prenatal nicotine exposure: Implications for sudden infant death syndrome

  Brain Research Bulletin. 1995;38(1):69-75.
  109

• 212.

  1995

  K.D. Whitney; F.J. Seidler; T.A. Slotkin

  Developmental neurotoxicity of chlorpyrifos: Cellular mechanisms

  Toxicology and Applied Pharmacology. 1995;134(1):53-62.
  187

• 213.

  1995

  T.A. Slotkin; B.A. Lorber; E.C. McCook; G.A. Barnes; F.J. Seidler

  Neural input and the development of adrenergic intracellular signaling: Neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase

  Developmental Brain Research. 1995;88(1):17-29.
  18

• 214.

  1995

  F. Schachat; F.J. Seidler; T.A. Slotkin

  The developmental switch in ventricular myosin expression in vivo is not triggered by an increase in cyclic AMP

  Reproduction, Fertility and Development. 1995;7(5):1361-1367.
  3

• 215.

  1995

  C.M. Tolson; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Does concurrent or prior nicotine exposure interact with neonatal hypoxia to produce cardiac cell damage?

  Teratology. 1995;52(5):298-305.
  22

• 216.

  1994

  J.P. Wagner; F.J. Seidler; S.E. Lappi; E.C. McCook; T.A. Slotkin

  Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: Beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression

  Journal of Pharmacology and Experimental Therapeutics. 1994;271(1):472-483.
  15

• 217.

  1994

  T.A. Slotkin; C.B. Nemeroff; G. Bissette; F.J. Seidler

  Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studies

  Journal of Clinical Investigation. 1994;94(2):696-702.
  48

• 218.

  1994

  T.A. Slotkin; C. Lau; E.C. McCook; S.E. Lappi; F.J. Seidler

  Glucocorticoids enhance intracellular signaling via adenylate cyclase at three distinct loci in the fetus: A mechanism for heterologous teratogenic sensitization?

  Toxicology and Applied Pharmacology. 1994;127(1):64-75.
  32

• 219.

  1994

  F.J. Seidler; E.S. Albright; S.E. Lappi; T.A. Slotkin

  In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: Catecholamine release by nicotine in immature rat brain regions

  Developmental Brain Research. 1994;82(1-2):1-8.
  21

• 220.

  1994

  K.S. Kauffman; F.J. Seidler; T.A. Slotkin

  Prenatal dexamethasone exposure causes loss of neonatal hypoxia tolerance: Cellular mechanisms

  Pediatric Research. 1994;35(5):515-522.
  27

• 221.

  1994

  J.P. Wagner; F.J. Seidler; F.H. Schachat; T.A. Slotkin

  Beta adrenergic control of c-fos protooncogene expression in developing rat brain regions

  Journal of Pharmacology and Experimental Therapeutics. 1994;269(3):1292-1299.
  17

• 222.

  1994

  Y.R. Spraggins; F.J. Seidler; T.A. Slotkin

  Cocaine exacerbates hypoxia-induced cell damage in the developing brain: Effects on ornithine decarboxylase activity and protein synthesis

  Biology of the Neonate. 1994;66(5):254-266.
  5

• 223.

  1993

  E.A. Zahalka; F.J. Seidler; J. Yanai; T.A. Slotkin

  Fetal nicotine exposure alters ontogeny of M₁-receptors and their link to G-proteins

  Neurotoxicology and Teratology. 1993;15(2):107-115.
  36

• 224.

  1993

  T.A. Slotkin; E.C. McCook; F.J. Seidler

  Glucocorticoids regulate the development of intracellular signaling: Enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure

  Brain Research Bulletin. 1993;32(4):359-364.
  10

• 225.

  1993

  X. Bian; F.J. Seidler; C. Olsen; J.R. Raymond; T.A. Slotkin

  Effects of fetal dexamethasone exposure on postnatal control of cardiac adenylate cyclase: β-adrenergic receptor coupling to G(s) regulatory protein

  Teratology. 1993;48(2):169-177.
  17

• 226.

  1993

  J. Yanai; Y. Rogel-Fuchs; C.G. Pick; T. Slotkin; F.J. Seidler; E.A. Zahalka; M.E. Newman

  Septohippocampal cholinergic changes after destruction of the A10-septal dopaminergic pathways

  Neuropharmacology. 1993;32(2):113-117.
  18

• 227.

  1993

  M.W. Wood; F.J. Seidler; T.A. Slotkin

  Immediate decline in DNA synthesis in neonatal rat lung caused by exposure to 100% oxygen

  Research Communications in Chemical Pathology and Pharmacology. 1993;80(3):323-328.
  4

• 228.

  1993

  E.A. Zahalka; F.J. Seidler; T.A. Slotkin

  Dexamethasone treatment in utero enhances neonatal cholinergic nerve terminal development in rat brain

  Research Communications in Chemical Pathology and Pharmacology. 1993;81(2):191-198.
  11

• 229.

  1993

  F.J. Seidler; T.A. Slotkin

  Prenatal cocaine and cell development in rat brain regions: Effects on ornithine decarboxylase and macromolecules

  Brain Research Bulletin. 1993;30(1-2):91-99.
  15

• 230.

  1993

  J.B. Pracyk; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Pituitary-thyroid axis reactivity to hyper- and hypothyroidism in the perinatal period: Ontogeny of regulation of regulation and long-term programming of responses

  Journal of Developmental Physiology. 1993;18(3):105-109.
  28

• 231.

  1993

  T.A. Slotkin; S.E. Lappi; F.J. Seidler

  Impact of fetal nicotine exposure on development of rat brain regions: Critical sensitive periods or effects of withdrawal?

  Brain Research Bulletin. 1993;31(3-4):319-328.
  54

• 232.

  1993

  D.B. Miller; F.J. Seidler

  Prenatal cocaine eliminates the sex-dependent differences in activation observed in adult rats after cocaine challenge

  Brain Research Bulletin. 1993;33(2):179-182.
  26

• 233.

  1993

  X. Bian; F.J. Seidler; T.A. Slotkin

  Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity

  Teratology. 1993;47(2):109-117.
  40

• 234.

  1993

  E.A. Zahalka; F.J. Seidler; S.E. Lappi; J. Yanai; T.A. Slotkin

  Differential development of cholinergic nerve terminal markers in rat brain regions: Implications for nerve terminal density, impulse activity and specific gene expression

  Brain Research. 1993;601(1-2):221-229.
  50

• 235.

  1993

  T.A. Slotkin; D.J. Johnson; F.J. Seidler

  Acute effects of cocaine on ornithine decarboxylase activity in fetal and neonatal rat heart: Evidence for cardiotoxicity

  Biology of the Neonate. 1993;63(5):290-296.
  4

• 236.

  1993

  E.D. Levin; F.J. Seidler

  Sex-related spatial learning differences after prenatal cocaine exposure in the young adult rat

  NeuroToxicology. 1993;14(1):23-28.
  37

• 237.

  1992

  E.A. Zahalka; F.J. Seidler; S.E. Lappi; E.C. Mccook; J. Yanai; T.A. Slotkin

  Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: Differential effects on choline acetyltransferase activity and [³H]hemicholinium-3 binding

  Neurotoxicology and Teratology. 1992;14(6):375-382.
  57

• 238.

  1992

  T.A. Slotkin; F.J. Seidler

  Transient postnatal elevation of norepinephrine content and turnover in brain regions of rats exposed to terbutaline prenatally: Evidence for autoregulation of noradrenergic development?

  Research Communications in Chemical Pathology and Pharmacology. 1992;76(3):269-278.
  7

• 239.

  1992

  R.Q. Carlos; F.J. Seidler; T.A. Slotkin

  Fetal dexamethasone exposure alters macromolecular characteristics of rat brain development: A critical period for regionally selective alterations?

  Teratology. 1992;46(1):45-59.
  41

• 240.

  1992

  M.M. Briggs; F.J. Seidler; T.A. Slotkin; F.H. Schachat

  Ontogenetic transition of cardiac myosin heavy chain isoforms in rat ventricle: Effects of fetal exposure to β-adrenergic agonists or antagonists

  Journal of Developmental Physiology. 1992;17(4):201-206.
  1

• 241.

  1992

  X.-P. Bian; F.J. Seidler; T.A. Slotkin

  Promotional role for glucocorticoids in the development of intracellular signalling: Enhanced cardiac and renal adenylate cyclase reactivity to β-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure

  Journal of Developmental Physiology. 1992;17(6):289-297.
  30

• 242.

  1992

  X. Bian; M.M. Briggs; F.H. Schachat; F.J. Seidler; T.A. Slotkin

  Glucocorticoids accelerate the ontogenetic transition of cardiac ventricular myosin heavy-chain isoform expression in the rat: Promotion by prenatal exposure to a low dose of dexamethasone

  Journal of Developmental Physiology. 1992;18(1):35-42.
  12

• 243.

  1992

  W. Lin; F.J. Seidler; E.C. McCook; T.A. Slotkin

  Overexpression of α₂-adrenergic receptors in fetal rat heart: Receptors in search of a function

  Journal of Developmental Physiology. 1992;17(4):183-187.
  11

• 244.

  1992

  T.A. Slotkin; F.J. Seidler; R.J. Kavlock; J.A. Gray

  Fetal dexamethasone exposure accelerates development of renal function: Relationship to dose, cell differentiation and growth inhibition

  Journal of Developmental Physiology. 1992;17(2):55-61.
  18

• 245.

  1992

  F.J. Seidler; T.A. Slotkin

  Fetal cocaine exposure causes persistent noradrenergic hyperactivity in rat brain regions: Effects on neurotransmitter turnover and receptors

  Journal of Pharmacology and Experimental Therapeutics. 1992;263(2):413-421.
  51

• 246.

  1992

  T.A. Slotkin; F.J. Seidler; R.J. Kavlock; J.V. Bartolome

  Thyroid hormone differentially regulates cellular development in neonatal rat heart and kidney

  Teratology. 1992;45(3):303-312.
  11

• 247.

  1992

  T.A. Slotkin; S.E. Lappi; E.C. McCook; M.I. Tayyeb; J.P. Eylers; F.J. Seidler

  Glucocorticoids and the development of neuronal function: Effects of prenatal dexamethasone exposure on central noradrenergic activity

  Biology of the Neonate. 1992;61(5):326-336.
  62

• 248.

  1992

  J.P. O'Callaghan; F.J. Seidler

  1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced astrogliosis does not require activation of ornithine decarboxylase

  Neuroscience Letters. 1992;148(1-2):105-108.
  12

• 249.

  1992

  F.J. Seidler; E.D. Levin; S.E. Lappi; T.A. Slotkin

  Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions

  Developmental Brain Research. 1992;69(2):288-291.
  50

• 250.

  1992

  T.A. Slotkin; E.C. McCook; S.E. Lappi; F.J. Seidler

  Altered development of basal and forskolin-stimulated adenylate cyclase activity in brain regions of rats exposed to nicotine prenatally

  Developmental Brain Research. 1992;68(2):233-239.
  34

• 251.

  1992

  F.J. Seidler; S.E. Lappi; T.A. Slotkin

  Effects of prenatal cocaine exposure on development of rat cardiac adrenergic receptors and their control of adenylate cyclase activity

  Research Communications in Substances of Abuse. 1992;13(3):237-246.
  1

• 252.

  1991

  W.T. Smith IV; F.J. Seidler; T.A. Slotkin

  Acute stimulation of ornithine decarboxylase in neonatal rat brain regions by nicotine: a central receptor-mediated process?

  Developmental Brain Research. 1991;63(1-2):85-93.
  11

• 253.

  1991

  T.A. Slotkin; E.C. McCook; C.B. Nemeroff; F.J. Seidler

  Species differences in alpha 2-adrenergic regulation of platelet adenylate cyclase.

  Research Communications in Chemical Pathology and Pharmacology. 1991;72(3):259-271.
  9

• 254.

  1991

  S.M. Koegler; F.J. Seidler; J.R. Spencer; T.A. Slotkin

  Ischemia contributes to adverse effects of cocaine on brain development: Suppression of ornithine decarboxylase activity in neonatal rat

  Brain Research Bulletin. 1991;27(6):829-834.
  18

• 255.

  1991

  H.E. Nye; F.J. Seidler; T.A. Slotkin

  Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: Effects of cocaine and related drugs

  Journal of Pharmacology and Experimental Therapeutics. 1991;259(3):976-981.
  4

• 256.

  1991

  C.B. Nemeroff; G. Bissette; T.A. Slotkin; F.J. Seidler; B.E. Miller; H. Ghanbari

  Recent advances in the neurochemical pathology of Alzheimer's disease. Studies of neuropeptides, cholinergic function and Alzheimer's disease- associated protein

  Annals of the New York Academy of Sciences. 1991;640:193-196.
  4

• 257.

  1991

  R.A. Huff; F.J. Seidler; T.A. Slotkin

  Glucocorticoids regulate the ontogenetic transition of adrenergic receptor subtypes in rat liver

  Life Sciences. 1991;48(11):1059-1065.
  31

• 258.

  1991

  T.A. Slotkin; S.E. Lappi; M.I. Tayyeb; F.J. Seidler

  Dose-dependent glucocorticoid effects on noradrenergic synaptogenesis in rat brain: Ontogeny of [³H]desmethylimipramine binding sites after fetal exposure to dexamethasone

  Research Communications in Chemical Pathology and Pharmacology. 1991;73(1):3-19.
  15

• 259.

  1991

  X.-P. Bian; F.J. Seidler; T.A. Slotkin

  Promotional role for glucocorticoids in the development of intracellular signalling: Enhanced cardiac and renal adenylate cyclase reactivity to β-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure¹

  Journal of Developmental Physiology. 1991;16(6):331-339.
  5

• 260.

  1991

  R.Q. Carlos; F.J. Seidler; S.E. Lappi; T.A. Slotkin

  Fetal dexamethasone exposure affects basal ornithine decarboxylase activity in developing rat brain regions and alters acute responses to hypoxia and maternal separation

  Biology of the Neonate. 1991;59(2):69-77.
  10

• 261.

  1991

  C.P. Duncan; F.J. Seidler; T.A. Slotkin

  Effects of MK-801 on DNA synthesis in neonatal rat brain regions under normoxic and hypoxic conditions

  Developmental Brain Research. 1991;58(1):67-71.
  2

• 262.

  1991

  B.J. McFarland; F.J. Seidler; T.A. Slotkin

  Inhibition of DNA synthesis in neonatal rat brain regions caused by acute nicotine administration

  Developmental Brain Research. 1991;58(2):223-229.
  68

• 263.

  1991

  R.Q. Carlos; F.J. Seidler; T.A. Slotkin

  Fetal dexamethasone exposure sensitizes neonatal rat brain to hypoxia: Effects on protein and DNA synthesis

  Developmental Brain Research. 1991;64(1-2):161-166.
  9

• 264.

  1991

  J.P. Wagner; F.J. Seidler; T.A. Slotkin

  Presynaptic input regulates development of β-adrenergic control of rat brain ornithine decarboxylase: Effects of 6-hydroxydopamine or propranolol

  Brain Research Bulletin. 1991;26(6):885-890.
  11

• 265.

  1991

  T.A. Slotkin; S.E. Lappi; M.I. Tayyeb; F.J. Seidler

  Chronic prenatal nicotine exposure sensitizes rat brain to acute postnatal nicotine challenge as assessed with ornithine decarboxylase

  Life Sciences. 1991;49(9):665-670.
  12

• 266.

  1991

  J.A. Gray; R.J. Kavlock; F.J. Seidler; T.A. Slotkin

  Neural factors in the development of renal function: Effect of neonatal central catecholaminergic lesions with 6-hydroxydopamine

  Journal of Developmental Physiology. 1991;15(6):325-330.
  4

• 267.

  1991

  T.A. Slotkin; F.J. Seidler; R.J. Kavlock; J.V. Bartolome

  Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: Effects on DNA and protein in whole tissues

  Teratology. 1991;43(4):301-306.
  26

• 268.

  1990

  H.A. Navarro; T.A. Slotkin; M.I. Tayyeb; S.E. Lappi; F.J. Seidler

  Effects of fetal nicotine exposure on development of adrenergic receptor binding in rat brain regions: Selective changes in α₁-receptors

  Research Communications in Substances of Abuse. 1990;11(3):95-103.
  14

• 269.

  1990

  F.J. Seidler; J.M. Bell; T.A. Slotkin

  Undernutrition and overnutrition in the neonatal rat: Long-term effects on noradrenergic pathways in brain regions

  Pediatric Research. 1990;27(2):191-197.
  29

• 270.

  1990

  H.A. Navarro; E. Mills; F.J. Seidler; F.E. Baker; S.E. Lappi; M.I. Tayyeb; J.R. Spencer; T.A. Slotkin

  Prenatal nicotine exposure impairs β-adrenergic function: Persistent chronotropic subsensitivity despite recovery from deficits in receptor binding

  Brain Research Bulletin. 1990;25(2):233-237.
  49

• 271.

  1990

  T.A. Slotkin; H.A. Navarro; E.C. McCook; F.J. Seidler

  Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues

  Life Sciences. 1990;47(17):1561-1567.
  34

• 272.

  1990

  F.J. Seidler; T.A. Slotkin

  Effects of acute hypoxia on neonatal rat brain: Regionally selective long-term alterations in catecholamine levels and turnover

  Brain Research Bulletin. 1990;24(2):157-161.
  35

• 273.

  1990

  T.A. Slotkin; F.J. Seidler; B.J. Crain; J.M. Bell; G. Bissette; C.B. Nemeroff

  Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: Implications for etiology and therapy

  Proceedings of the National Academy of Sciences of the United States of America. 1990;87(7):2452-2455.
  47

• 274.

  1990

  C.P. Duncan; F.J. Seidler; S.E. Lappi; T.A. Slotkin

  Dual control of DNA synthesis by α- and β-adrenergic mechanisms in normoxic and hypoxic neonatal rat brain

  Developmental Brain Research. 1990;55(1):29-33.
  26

• 275.

  1990

  X.-P. Bian; F.J. Seidler; J. Bartolome; R.J. Kavlock; M. Bartolome; T.A. Slotkin

  Dose-dependent effect of prenatal dexamethasone treatment on β-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP

  Journal of Developmental Physiology. 1990;14(3):125-130.
  11

• 276.

  1990

  T. Anderson-Brown; T.A. Slotkin; F.J. Seidler

  Cocaine acutely inhibits DNA synthesis in developing rat brain regions: Evidence for direct actions

  Brain Research. 1990;537(1-2):197-202.
  41

• 277.

  1990

  T.A. Slotkin; E.M. Kudlacz; S.E. Lappi; M.I. Tayyeb; F.J. Seidler

  Fetal terbutaline exposure causes selective postnatal increases in cerebellar α-adrenergic receptor binding

  Life Sciences. 1990;47(22):2051-2057.
  18

• 278.

  1989

  F.J. Seidler; E. Mills

  Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat

  Life Sciences. 1989;45(5):379-381.
  2

• 279.

  1989

  T.A. Slotkin; F.E. Baker; S.S. Dobbins; J.P. Eylers; S.E. Lappi; F.J. Seidler

  Prenatal terbutaline exposure in the rat: Selective effects on development of noradrenergic projections to cerebellum

  Brain Research Bulletin. 1989;23(4-5):263-265.
  17

• 280.

  1989

  Q.-C. Hou; F.J. Seidler; T.A. Slotkin

  Development of the linkage of β-adrenergic receptors to cardiac hypertrophy and heart rate control: Neonatal sympathectomy with 6-hydroxydopamine

  Journal of Developmental Physiology. 1989;11(5):305-311.
  13

• 281.

  1989

  Q.-C. Hou; F.E. Baker; F.J. Seidler; M. Bartolome; J. Bartolome; T.A. Slotkin

  Role of sympathetic neurons in development of β-adrenergic control of ornithine decarboxylase activity in peripheral tissues: Effects of neonatal 6-hydroxydopamine treatment

  Journal of Developmental Physiology. 1989;11(3):139-146.
  11

• 282.

  1989

  H.A. Navarro; F.J. Seidler; R.D. Schwartz; F.E. Baker; S.S. Dobbins; T.A. Slotkin

  Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth

  Brain Research Bulletin. 1989;23(3):187-192.
  94

• 283.

  1989

  H.A. Navarro; F.J. Seidler; J.P. Eylers; F.E. Baker; S.S. Dobbins; S.E. Lappi; T.A. Slotkin

  Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain

  Journal of Pharmacology and Experimental Therapeutics. 1989;251(3):894-900.
  122

• 284.

  1989

  A.L. Sylvia; F.J. Seidler; T.A. Slotkin

  Effect of transient hypoxia on oxygenation of the developing rat brain: Relationships among haemoglobin saturation, autoregulation of blood flow and mitochondrial redox state

  Journal of Developmental Physiology. 1989;12(5):287-292.
  13

• 285.

  1988

  C. Lau; F.J. Seidler; A.M. Cameron; H.A. Navarro; J.M. Bell; J. Bartolome; T.A. Slotkin

  Nutritional influences on adrenal chromaffin cell development: Comparison with central neurons

  Pediatric Research. 1988;24(5):583-587.
  34

• 286.

  1988

  H.A. Navarro; F.J. Seidler; W.L. Whitmore; T.A. Slotkin

  Prenatal exposure to nicotine via maternal infusions: Effects on development of catecholamine systems

  Journal of Pharmacology and Experimental Therapeutics. 1988;244(3):940-944.
  73

• 287.

  1988

  T.A. Slotkin; F.J. Seidler

  Adrenomedullary catecholamine release in the fetus and newborn: Secretory mechanisms and their role in stress and survival

  Journal of Developmental Physiology. 1988;10(1):1-16.
  89

• 288.

  1988

  T.A. Slotkin; R. Windh; W.L. Whitmore; F.J. Seidler

  Adrenergic control of DNA synthesis in developing rat brain regions: Effects of intracisternal administration of isoproterenol

  Brain Research Bulletin. 1988;21(5):737-740.
  21

• 289.

  1988

  T.A. Slotkin; F.J. Seidler

  Stress in the fetus and newborn.

  Advances in Experimental Medicine and Biology. 1988;245:283-294.
  3

• 290.

  1988

  T.A. Slotkin; F.J. Seidler; K. Haim; A.M. Cameron; L. Antolick; C. Lau

  Neonatal central catecholaminergic lesions with intracisternal 6-hydroxydopamine: Effects on development of presynaptic and postsynaptic components of peripheral sympathetic pathways and on the ornithine decarboxylase/polyamine system in heart, lung and kidney

  Journal of Pharmacology and Experimental Therapeutics. 1988;247(3):975-982.
  4

• 291.

  1987

  T.A. Slotkin; L. Orband-Miller; K.L. Queen; W.L. Whitmore; F.J. Seidler

  Effects of prenatal nicotine exposure on biochemical development of rat brain regions: Maternal drug infusions via osmotic minipumps

  Journal of Pharmacology and Experimental Therapeutics. 1987;240(2):602-611.
  84

• 292.

  1987

  F.J. Seidler; K.K. Brown; P.G. Smith; T.A. Slotkin

  Toxic effects of hypoxia on neonatal cardiac function in the rat: α-adrenergic mechanisms

  Toxicology Letters. 1987;37(1):79-84.
  3

• 293.

  1986

  F.J. Seidler; T.A. Slotkin

  Non-neurogenic adrenal catecholamine release in the neonatal rat: exocytosis or diffusion?

  Brain research. 1986;393(2):274-277.
  6

• 294.

  1986

  Joanne M. Bell; William L. Whitmore; Gloria Barnes; Frederic J. Seidler; Theodore A. Slotkin

  Perinatal dietary exposure to soy lecithin: Altered sensitivity to central cholinergic stimulation

  International Journal of Developmental Neuroscience. 1986;4(6):497-501.
  6

• 295.

  1986

  L. Friedman; D.W. Gaines; F.R. Alleva; F.J. Seidler; T.J. Flynn; T.A. Slotkin; T. Balazs

  Macromolecular levels, DNA synthesis and ornithine decarboxylase activity in leg muscles from 6-mercaptopurine-treated rats

  Toxicology and Industrial Health. 1986;2(2):57-68.
  0

• 296.

  1986

  F.J. Seidler; T.A. Slotkin

  Ontogeny of adrenomedullary responses to hypoxia and hypoglycemia: Role of splanchnic innervation

  Brain Research Bulletin. 1986;16(1):11-14.
  41

• 297.

  1986

  F.J. Seidler; T.A. Slotkin

  Non-neurogenic adrenal catecholamine release in the neonatal rat: Exocytosis or diffusion?

  Developmental Brain Research. 1986;28(2):274-277.
  7

• 298.

  1985

  F.J. Seidler; T.A. Slotkin

  Adrenomedullary function in the neonatal rat: Responses to acute hypoxia

  Journal of Physiology. 1985;VOL. 358:1-16.
  90

• 299.

  1984

  J. Bartolome; W.L. Whitmore; F.J. Seidler; T.A. Slotkin

  Exposure to methylmercury in utero: Effects on biochemical development of catecholamine neurotransmitter systems

  Life Sciences. 1984;35(6):657-670.
  10

• 300.

  1984

  F.J. Seidler; T.A. Slotkin

  Adrenomedullary catecholamine (CA) release in the neonatal rat

  Federation Proceedings. 1984;43(3):no. 277.
  0

• 301.

  1983

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore

  Critical periods for the role of ornithine decarboxylase and the polyamines in growth and development of the rat: Effects of exposure to α-difluoromethylornithine during discrete prenatal or postnatal intervals

  International Journal of Developmental Neuroscience. 1983;1(2):113-127.
  5

• 302.

  1983

  G. Morris; F.J. Seidler; T.A. Slotkin

  Stimulation of ornithine decarboxylase by histamine or norepinephrine in brain regions of the developing rat: Evidence for biogenic amines as trophic agents in neonatal brain development

  Life Sciences. 1983;32(14):1565-1571.
  10

• 303.

  1982

  Alberto Grignolo; Frederic J. Seidler; Maria Bartolome; Cynthia M. Kuhn; Theodore A. Slotkin; Saul M. Schanberg

  Norepinephrine content of the rat kidney during development: Alterations induced by perinatal methadone

  Life Sciences. 1982;31(26):3009-3016.
  2

• 304.

  1982

  Jorge Bartolome; Patricia Trepanier; Elise A. Chait; Frederic J. Seidler; Randy Deskin; Theodore A. Slotkin

  Neonatal methylmercury poisoning in the rat: Effects on development of central catecholamine neurotransmitter systems

  Toxicology and Applied Pharmacology. 1982;65(1):92-99.
  6

• 305.

  1982

  Theodore A. Slotkin; Stephanie J. Weigel; William L. Whitmore; Frederic J. Seidler

  Maternal methadone administration: Deficit in development of alpha-noradrenergic responses in developing rat brain as assessed by norepinephrine stimulation of ³³P_i incorporation into phospholipids in vivo

  Biochemical Pharmacology. 1982;31(10):1899-1902.
  0

• 306.

  1982

  C.J. Chantry; F.J. Seidler; T.A. Slotkin

  Non-neurogenic mechanism for reserpine-induced release of catecholamines from the adrenal medulla of neonatal rats: Possible modulation by opiate receptors

  Neuroscience. 1982;7(3):673-678.
  9

• 307.

  1982

  F.J. Seidler; W.L. Whitmore; T.A. Slotkin

  Delays in growth and biochemical development of rat brain caused by maternal methadone administration: Are the alterations in synaptogenesis and cellular maturation independent of reduced maternal food intake?

  Developmental Neuroscience. 1982;5(1):13-18.
  3

• 308.

  1982

  T.A. Slotkin; S.J. Weigel; F.J. Seidler; W.L. Whitmore

  Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: Potential participation of altered polyamine levels in growth impairment

  Toxicology Letters. 1982;14(3-4):131-135.
  0

• 309.

  1982

  T.A. Slotkin; G. Barnes; C. Lau; F.J. Seidler; P. Trepanier; S.J. Weigel; W.L. Whitmore

  Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: Role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover

  Journal of Pharmacology and Experimental Therapeutics. 1982;221(3):686-693.
  11

• 310.

  1982

  T.A. Slotkin; F.J. Seidler; P.A. Trepanier; W.L. Whitmore; L. Lerea; G.A. Barnes; S.J. Weigel; J. Bartolome

  Ornithine decarboxylase and polyamines in tissues of the neonatal rat: Effects of α-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase

  Journal of Pharmacology and Experimental Therapeutics. 1982;222(3):741-745.
  28

• 311.

  1982

  T.A. Slotkin; A. Grignolo; W.L. Whitmore; L. Lerea; P.A. Trepanier; G.A. Barnes; S.J. Weigel; F.J. Seidler; J. Bartolome

  Impaired development of central and peripheral catecholamine neurotransmitter systems in preweanling rats treated with α-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase

  Journal of Pharmacology and Experimental Therapeutics. 1982;222(3):746-751.
  6

• 312.

  1981

  T.A. Slotkin; S.J. Weigel; G.A. Barnes; W.L. Whitmore; F.J. Seidler

  Alterations in the development of catecholamine turnover induced by perinatal methadone: Differences in central vs. peripheral sympathetic nervous systems

  Life Sciences. 1981;29(24):2519-2525.
  1

• 313.

  1981

  R. Deskin; F.J. Seidler; W.L. Whitmore; T.A. Slotkin

  Development of α-noradrenergic and dopaminergic receptor systems depends on maturation of their presynaptic nerve terminals in the rat brain

  Journal of Neurochemistry. 1981;36(5):1683-1690.
  13

• 314.

  1981

  F.J. Seidler; T.A. Slotkin

  Development of central control of norepinephrine turnover and release in the rat heart: Responses to tyramine, 2-deoxyglucose and hydralazine

  Neuroscience. 1981;6(10):2081-2086.
  8

• 315.

  1981

  R. Deskin; F.J. Seidler; W.L. Whitmore; T.A. Slotkin

  Development of rat brain alpha-noradrenergic and dopaminergic receptor systems depends upon maturation of their presynaptic nerve terminals

  Federation Proceedings. 1981;40(3 I):78.
  0

• 316.

  1981

  F.J. Seidler; T.A. Slotkin

  Development of central control of cardiac norepinephrine turnover in the rat heart

  Federation Proceedings. 1981;40(3 I):82.
  0

• 317.

  1981

  N. Subramanian; W.L. Whitmore; F.J. Seidler; T.A. Slotkin

  Ontogeny of histaminergic neurotransmission in the rat brain: Concomitant development of neuronal histamine, H-1 receptors, and H-1 receptor-mediated stimulation of phospholipid turnover

  Journal of Neurochemistry. 1981;36(3):1137-1141.
  5

• 318.

  1980

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore; Maria Salvaggio; Donna L. Bareis

  Release of [³H]norepinephrine from synaptic vesicles isolated from rat brain after the intracisternal administration of [³h]norepinephrine: Influence of nucleotides, ions and drugs and destabilization of transmitter storage caused by acute or chronic lithium administration

  Neuroscience. 1980;5(4):753-762.
  1

• 319.

  1980

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore

  Precocious development of sympatho-adrenal function in rats whose mothers received methadone

  Life Sciences. 1980;26(20):1657-1663.
  0

• 320.

  1980

  N. Subramanian; W.L. Whitmore; F.J. Seidler; T.A. Slotkin

  Histamine stimulates brain phospholipid turnover through a direct, H-1 receptor-mediated mechanism

  Life Sciences. 1980;27(14):1315-1319.
  1

• 321.

  1980

  R. Deskin; E. Mills; W.L. Whitmore; F.J. Seidler; T.A. Slotkin

  Maturation of sympathetic neurotransmission in the rat heart. VI. The effect of neonatal central catecholaminergic lesions

  Journal of Pharmacology and Experimental Therapeutics. 1980;215(2):342-347.
  3

• 322.

  1980

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore

  Effects of maternal methadone administration on ornithine decarboxylase in brain and heart of the offspring: Relationships of enzyme activity to dose and to growth impairment in the rat

  Life Sciences. 1980;26(11):861-867.
  4

• 323.

  1979

  F.J. Seidler; T.A. Slotkin

  Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the preweanling rat

  British Journal of Pharmacology. 1979;65(3):431-434.
  16

• 324.

  1979

  T.A. Slotkin; W.L. Whitmore; M. Salvaggio; F.J. Seidler

  Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat

  Life Sciences. 1979;24(13):1223-1230.
  10

• 325.

  1979

  T.A. Slotkin; M. Salvaggio; F.J. Seidler; W.L. Whitmore

  Structural characteristics for inhibition of [³H]norepinephrine uptake into rat brain synaptic vesicles by beta-carboline, indolealkylamine, phenethylamine and n-alkylamine derivatives

  Molecular Pharmacology. 1979;15(3):607-619.
  1

• 326.

  1978

  D.F. Kirksey; F.J. Seidler; T.A. Slotkin

  Ontogeny of (-)-[³H]norepinephrine uptake properties of synaptic storage vesicles of rat brain

  Brain Research. 1978;150(2):367-375.
  2

• 327.

  1978

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore

  Methadone inhibits serotonin and norepinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo

  European Journal of Pharmacology. 1978;49(4):357-362.
  2

• 328.

  1978

  F.J. Seidler; W.L. Whitmore; T.A. Slotkin

  Age-dependence of inhibition of rat brain synaptic vesicle [³H]Norepinephrine uptake caused by administration of a single dose of reserpine. Persistence of inhibition in adults but not in neonates

  Journal of Pharmacology and Experimental Therapeutics. 1978;206(3):652-660.
  6

• 329.

  1978

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore; M. Salvaggio; C. Lau

  Ionic and nucleotide cofactor requirements for uptake of [ ³H]-norepinephrine by rat brain synaptic vesicle preparations

  Molecular Pharmacology. 1978;14(5):868-878.
  0

• 330.

  1978

  T.A. Slotkin; F.J. Seidler; W.L. Whitmore; C. Lau; M. Salvaggio; D.F. Kirksey

  Rat brain synaptic vesicles: Uptake specificities of [ ³H]norepinephrine and [ ³H]serotonin in preparations from whole brain and brain regions

  Journal of Neurochemistry. 1978;31(4):961-968.
  4

• 331.

  1977

  Frederic J. Seidler; D.F. Kirksey; Christopher Lau; William L. Whitmore; Theodore A. Slotkin

  Uptake of (-) ³H-norepinephrine by storage vesicles prepared from whole rat brain: Properties of the uptake system and its inhibition by drugs

  Life Sciences. 1977;21(8):1075-1085.
  2

• 332.

  1977

  C. Lau; J. Bartolome; F.J. Seidler; T.A. Slotkin

  Critical periods for effects of prenatal reserpine administration on development of rat brain and adrenal medulla

  Neuropharmacology. 1977;16(12):799-809.
  1

• 333.

  1976

  Jorge Bartolomé; Maria Bartolomé; Frederic J. Seidler; Thomas R. Anderson; Theodore A. Slotkin

  Effects of early postnatal guanethidine administration on adrenal medulla and brain of developing rats

  Biochemical Pharmacology. 1976;25(21):2387-2390.
  2

• 334.

  1976

  Thomas R. Anderson; Jorge Bartolomé; Frederic J. Seidler; Christopher Lau; Theodore A. Slotkin

  Morphine-reserpine interactions in the adrenal medulla

  Toxicology and Applied Pharmacology. 1976;36(3):533-541.
  0

• 335.

  1976

  J. Bartolome; F.J. Seidler; T.R. Anderson; T.A. Slotkin

  Effects of prenatal reserpine administration on development of the rat adrenal medulla and central nervous system

  Journal of Pharmacology and Experimental Therapeutics. 1976;197(2):293-302.
  2

• 336.

  1976

  T.A. Slotkin; C. Lau; M. Bartolome; F.J. Seidler

  Catecholamine synthesis, storage and release in adrenal medulla and whole brain during acute and chronic methadone administration

  Biochemical Pharmacology. 1976;25(22):2523-2527.
  1

• 337.

  1976

  F.J. Seidler; T.A. Slotkin

  Effects of chronic nicotine admin)stration on the denervated rat adrenal medulla

  British Journal of Pharmacology. 1976;56(2):201-207.
  5

• 338.

  1976

  T.A. Slotkin; F.J. Seidler; C. Lau; J. Bartolomé; S.M. Schanberg

  Effects of chronic chlorisondamine administration on the sympatho adrenal axis

  Biochemical Pharmacology. 1976;25(11):1311-1315.
  3

• 339.

  1976

  T.A. Slotkin; C. Lau; M. Bartolome; F.J. Seidler

  Alteration by methadone of catecholamine uptake and release in isolated rat adrenomedullary storage vesicles

  Life Sciences. 1976;19(4):483-491.
  0

• 340.

  1975

  T.A. Slotkin; T.R. Anderson; F.J. Seidler; C. Lau

  Inhibition of epinephrine and metaraminol uptake into adrenal medullary vesicles by aralkylamines and alkylamines

  Biochemical Pharmacology. 1975;24(15):1413-1419.
  2

• 341.

  1975

  T.A. Slotkin; F.J. Seidler

  Acute and chronic effects of nicotine on synthesis and storage of catecholamines in the rat adrenal medulla

  Life Sciences. 1975;16(10):1613-1622.
  9

• 342.

  1974

  T.A. Slotkin; F.J. Seidler; M.D. Abou Donia

  Effects of tryptamines on epinephrine uptake into adrenal medullary vesicles

  Pharmacologist. 1974;16(2):No.379.
  0