Publications of James A Swenberg - ReachNC

375 Publications

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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1.
2013

Thomas B. Starr; James A. Swenberg

A novel bottom-up approach to bounding low-dose human cancer risks from chemical exposures
Regulatory Toxicology and Pharmacology. 2013;65(3):311-315.

0
2.
2013

James A. Swenberg; Benjamin C. Moeller; Kun Lu; Julia E. Rager; Rebecca C. Fry; Thomas B. Starr

Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment
Toxicologic Pathology. 2013;41(2):181-189.

0
3.
2013

Julia E. Rager; Benjamin C. Moeller; Melanie Doyle-Eisele; Dean Kracko; James A. Swenberg; Rebecca C. Fry

Formaldehyde and epigenetic alterations: MicroRNA changes in the nasal epithelium of nonhuman primates
Environmental Health Perspectives. 2013;121(3):339-344.

0
4.
2012

Kun Lu; Sessaly Craft; Jun Nakamura; Benjamin C. Moeller; James A. Swenberg

Use of LC-MS/MS and stable isotopes to differentiate hydroxymethyl and methyl DNA adducts from formaldehyde and nitrosodimethylamine
Chemical Research in Toxicology. 2012;25(3):664-675.

4
5.
2012

Jun Nakamura; Husamettin Gul; Xu Tian; Scott J. Bultman; James A. Swenberg

Detection of PIGO-deficient cells using proaerolysin: A valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system
PLoS ONE. 2012;7(3).

0
6.
2012

C.L. King; S. Ramachandran; S.G. Chaney; L. Collins; J.A. Swenberg; K.E. DeKrafft; W. Lin; L. Cicurel; M. Barbier

Debio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells
Cancer Chemotherapy and Pharmacology. 2012;69(3):665-677.

0
7.
2012

Esra Mutlu; Yo-Chan Jeong; Leonard B. Collins; Amy-Joan L. Ham; Patricia B. Upton; Gary Hatch; Darrell Winsett; Paul Evansky; James A. Swenberg

A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-oxoethyl)guanine in Sprague-Dawley rats
Chemical Research in Toxicology. 2012;25(2):391-399.

0
8.
2012

Dewakar Sangaraju; Melissa Goggin; Vernon Walker; James Swenberg; Natalia Tretyakova

NanoHPLC-nanoESI ⁺-MS/MS quantitation of Bis -N7-Guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene
Analytical Chemistry. 2012;84(3):1732-1739.

2
9.
2012

Kun Lu; Husamettin Gul; Patricia B. Upton; Benjamin C. Moeller; James A. Swenberg

Formation of hydroxymethyl DNA adducts in rats orally exposed to stable isotope labeled methanol
Toxicological Sciences. 2012;126(1):28-38.

0
10.
2012

Gunnar Boysen; Nadia I. Georgieva; Narisa K. Bordeerat; Radim J. Šram; Pamela Vacek; Richard J. Albertini; James A. Swenberg

Formation of 1,2: 3,4-diepoxybutane-specific hemoglobin adducts in 1,3-butadiene exposed workers
Toxicological Sciences. 2012;125(1):30-40.

3
11.
2011

Dawoon Jung; Cole W. Matson; Leonard B. Collins; Geoff Laban; Heather M. Stapleton; John W. Bickham; James A. Swenberg; Richard T. Di Giulio

Genotoxicity in Atlantic killifish (Fundulus heteroclitus) from a PAH-contaminated Superfund site on the Elizabeth River, Virginia
Ecotoxicology. 2011;20(8):1890-1899.

0
12.
2011

James W. Simpkins; James A. Swenberg; Noel Weiss; David Brusick; J. Charles Eldridge; James T. Stevens; Robert J. Handa; Russell C. Hovey; Tony M. Plant; Timothy P. Pastoor; et al.

Atrazine and breast cancer: A framework assessment of the toxicological and epidemiological evidence
Toxicological Sciences. 2011;123(2):441-459.

3
13.
2011

James A. Swenberg; Narisa K. Bordeerat; Gunnar Boysen; Sujey Carro; Nadia I. Georgieva; Jun Nakamura; John M. Troutman; Patricia B. Upton; Richard J. Albertini; Pamela M. Vacek; et al.

Corrigendum to "1,3-Butadiene: Biomarkers and application to risk assessment" (Chemico-Biological Interactions (2011) 192, 1-2, (150-154) DOI: 10.1016/j.cbi.2010.10.010)
Chemico-Biological Interactions. 2011;193(2):190.

0
14.
2011

Shinsuke Ito; Li Shen; Qing Dai; Susan C. Wu; Leonard B. Collins; James A. Swenberg; Chuan He; Yi Zhang

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
Science. 2011;333(6047):1300-1303.

191
15.
2011

Kuen-Yuh Wu; Su-Yin Chiang; Wei-Chung Shih; Chih-Chun Jean Huang; Ming-Feng Chen; James A. Swenberg

The application of mass spectrometry in molecular dosimetry: Ethylene oxide as an example
Mass Spectrometry Reviews. 2011;30(5):733-756.

5
16.
2011

Igor Koturbash; Anne Scherhag; Jessica Sorrentino; Kenneth Sexton; Wanda Bodnar; James A. Swenberg; Frederick A. Beland; Fernando Pardo-Manuel deVillena; Ivan Rusyn; Igor P. Pogribny

Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene
Toxicological Sciences. 2011;122(2):448-456.

4
17.
2011

Hans-Olov Adami; Sir Colin L. Berry; Charles B. Breckenridge; Lewis L. Smith; James A. Swenberg; Dimitrios Trichopoulos; Noel S. Weiss; Timothy P. Pastoor

Toxicology and epidemiology: Improving the science with a framework for combining toxicological and epidemiological evidence to establish causal inference
Toxicological Sciences. 2011;122(2):223-234.

8
18.
2011

Petra Begemann; Gunnar Boysen; Nadia I. Georgieva; Ramiah Sangaiah; Karl M. Koshlap; Hasan Koc; Daping Zhang; Bernard T. Golding; Avram Gold; James A. Swenberg

Identification and characterization of 2′-deoxyadenosine adducts formed by isoprene monoepoxides in vitro
Chemical Research in Toxicology. 2011;24(7):1048-1061.

0
19.
2011

James A. Swenberg; Narisa K. Bordeerat; Gunnar Boysen; Sujey Carro; Nadia I. Georgieva; Jun Nakamura; John M. Troutman; Patricia B. Upton; Richard J. Albertini; Pamela M. Vacek; et al.

1,3-Butadiene: Biomarkers and application to risk assessment
Chemico-Biological Interactions. 2011;192(1-2):150-154.

10
20.
2011

Melissa Goggin; Dewakar Sangaraju; Vernon E. Walker; Jeffrey Wickliffe; James A. Swenberg; Natalia Tretyakova

Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation
Chemical Research in Toxicology. 2011;24(6):809-817.

6
21.
2011

Igor Koturbash; Anne Scherhag; Jessica Sorrentino; Kenneth Sexton; Wanda Bodnar; Volodymyr Tryndyak; John R. Latendresse; James A. Swenberg; Frederick A. Beland; Igor P. Pogribny; et al.

Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene
Environmental Health Perspectives. 2011;119(5):635-640.

5
22.
2011

Lynn H. Pottenger; Richard A. Becker; Elizabeth J. Moran; James A. Swenberg

Workshop report: Identifying key issues underpinning the selection of linear or non-linear dose-response extrapolation for human health risk assessment of systemic toxicants
Regulatory Toxicology and Pharmacology. 2011;59(3):503-510.

1
23.
2011

John R. Ridpath; Shunichi Takeda; James A. Swenberg; Jun Nakamura

Convenient, multi-well plate-based DNA damage response analysis using DT40 mutants is applicable to a high-throughput genotoxicity assay with characterization of modes of action
Environmental and Molecular Mutagenesis. 2011;52(2):153-160.

2
24.
2011

Benjamin C. Moeller; Kun Lu; Melanie Doyle-Eisele; Jacob McDonald; Andrew Gigliotti; James A. Swenberg

Determination of N ²-hydroxymethyl-dG adducts in the nasal epithelium and bone marrow of nonhuman primates following ¹³CD ₂-formaldehyde inhalation exposure
Chemical Research in Toxicology. 2011;24(2):162-164.

15
25.
2011

Kun Lu; Benjamin Moeller; Melanie Doyle-Eisele; Jacob McDonald; James A. Swenberg

Molecular dosimetry of N ²-Hydroxymethyl-dG DNA adducts in rats exposed to formaldehyde
Chemical Research in Toxicology. 2011;24(2):159-161.

20
26.
2011

James A. Swenberg; Kun Lu; Benjamin C. Moeller; Lina Gao; Patricia B. Upton; Jun Nakamura; Thomas B. Starr

Endogenous versus exogenous DNA adducts: Their role in carcinogenesis, epidemiology, and risk assessment
Toxicological Sciences. 2011;120(SUPPL.1):S130-S145.

18
27.
2011

Kun Lu; Benjamin C. Moeller; James A. Swenberg

Further considerations for the implausibility of leukemia induction by formaldehyde
Toxicological Sciences. 2011;120(1):233.

0
28.
2011

Debadeep Bhattacharyya; Srinivas Ramachandran; Shantanu Sharma; Wimal Pathmasiri; Candice L. King; Irene Baskerville-Abraham; Gunnar Boysen; James A. Swenberg; Sharon L. Campbell; Nikolay V. Dokholyan; et al.

Flanking bases influence the nature of DNA distortion by Platinum 1,2-intrastrand (GG) cross-links
PLoS ONE. 2011;6(8).

5
29.
2010

April M. Luke; Paul D. Chastain; Brian F. Pachkowski; Valeriy Afonin; Shunichi Takeda; David G. Kaufman; James A. Swenberg; Jun Nakamura

Accumulation of true single strand breaks and AP sites in base excision repair deficient cells
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2010;694(1-2):65-71.

2
30.
2010

Pamela M. Vacek; Richard J. Albertini; Radim J. Sram; Patricia Upton; James A. Swenberg

Hemoglobin adducts in 1,3-butadiene exposed Czech workers: Female-male comparisons
Chemico-Biological Interactions. 2010;188(3):668-676.

6
31.
2010

Rachael B. Cowerd; Melissa M. Asmar; J. McKee Alderman; Elizabeth A. Alderman; Alaina L. Garland; Walker H. Busby; Wanda M. Bodnar; Ivan Rusyn; Benjamin D. Medoff; Roland Tisch; et al.

Adiponectin lowers glucose production by increasing SOGA
American Journal of Pathology. 2010;177(4):1936-1945.

4
32.
2010

Paul D. Chastain II; Jun Nakamura; Shangbang Rao; Haitao Chu; Joseph G. Ibrahim; James A. Swenberg; David G. Kaufman

Abasic sites preferentially form at regions undergoing DNA replication
FASEB Journal. 2010;24(10):3674-3680.

3
33.
2010

Esra Mutlu; Leonard B. Collins; Matthew D. Stout; Patricia B. Upton; Laura R. Daye; Darrell Winsett; Gary Hatch; Paul Evansky; James A. Swenberg

Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N ²,3-ethenoguanine in tissues of adult and weanling rats following exposure to [¹³C₂]-VC
Chemical Research in Toxicology. 2010;23(9):1485-1491.

5
34.
2010

Joseph V. Rodricks; James A. Swenberg; Joseph F. Borzelleca; Robert R. Maronpot; Annette M. Shipp

Triclosan: A critical review of the experimental data and development of margins of safety for consumer products
Critical Reviews in Toxicology. 2010;40(5):422-484.

23
35.
2010

Melissa Goggin; Uthpala Seneviratne; James A. Swenberg; Vernon E. Walker; Natalia Tretyakova

Column switching HPLC-ESI⁺-MS/MS methods for quantitative analysis of exocyclic da adducts in the DNA of laboratory animals exposed to 1,3-butadiene
Chemical Research in Toxicology. 2010;23(4):808-812.

6
36.
2010

Kun Lu; Wenjie Ye; Li Zhou; Leonard B. Collins; Xian Chen; Avram Gold; Louise M. Ball; James A. Swenberg

Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers
Journal of the American Chemical Society. 2010;132(10):3388-3399.

11
37.
2010

Nadia I. Georgieva; Gunnar Boysen; Narisa Bordeerat; Vernon E. Walker; James A. Swenberg

Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene
Toxicological Sciences. 2010;115(2):322-329.

7
38.
2010

Kun Lu; Leonard B. Collins; Hongyu Ru; Edilberto Bermudez; James A. Swenberg

Distribution of DNA adducts caused by inhaled formaldehyde is consistent with induction of nasal carcinoma but not leukemia
Toxicological Sciences. 2010;116(2):441-451.

33
39.
2010

Kenjiro Asagoshi; Keizo Tano; Paul D. Chastain II; Noritaka Adachi; Eiichiro Sonoda; Koji Kikuchi; Hideki Koyama; Kenji Nagata; David G. Kaufman; Shunichi Takeda; et al.

FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells
Molecular Cancer Research. 2010;8(2):204-215.

7
40.
2010

Gunnar Boysen; Leonard B. Collins; Shengkai Liao; April M. Luke; Brian F. Pachkowski; Joanne L. Watters; James A. Swenberg

Analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine by ultra high pressure liquid chromatography-heat assisted electrospray ionization-tandem mass spectrometry
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2010;878(3-4):375-380.

9
41.
2010

John E. French; Bernard Leblanc; Gerald G. Long; Daniel Morton; Richard Storer; John Leighton; James Swenberg; Hiroyuki Tsuda

Panel discussion: Alternative mouse models for carcinogenicity assessment
Toxicologic Pathology. 2010;38(1):72-75.

0
42.
2009

Joanne L. Watters; Jessie A. Satia; Kerry-Ann Da Costa; Gunnar Boysen; Leonard B. Collins; Jason D. Morrow; Ginger L. Milne; James A. Swenberg

Comparison of three oxidative stress biomarkers in a sample of healthy adults Oxidative stress biomarkers in healthy adults J. L. Watters et al.
Biomarkers. 2009;14(8):587-595.

2
43.
2009

Brian F. Pachkowski; Keizo Tano; Valeriy Afonin; Rhoderick H. Elder; Shunichi Takeda; Masami Watanabe; James A. Swenberg; Jun Nakamura

Cells deficient in PARP-1 show an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1-proficient cells exposed to MMS
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2009;671(1-2):93-99.

8
44.
2009

Dawoon Jung; Youngeun Cho; Leonard B. Collins; James A. Swenberg; Richard T. Di Giulio

Effects of benzo[a]pyrene on mitochondrial and nuclear DNA damage in Atlantic killifish (Fundulus heteroclitus) from a creosote-contaminated and reference site
Aquatic Toxicology. 2009;95(1):44-51.

10
45.
2009

George S. Bailey; Gayle A. Orner; Clifford B. Pereira; James A. Swenberg

Response to the Waddell et al. letter
Chemical Research in Toxicology. 2009;22(9):1493-1494.

2
46.
2009

Sungkyoon Kim; Leonard B. Collins; Gunnar Boysen; James A. Swenberg; Avram Gold; Louise M. Ball; Blair U. Bradford; Ivan Rusyn

Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine
Toxicology. 2009;262(3):230-238.

9
47.
2009

Gunnar Boysen; Brian F. Pachkowski; Jun Nakamura; James A. Swenberg

The formation and biological significance of N7-guanine adducts
Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 2009;678(2):76-94.

25
48.
2009

Vernon E Walker; Dale M Walker; Quanxin Meng; Jacob D McDonald; Bobby R Scott; Steven K Seilkop; David J Claffey; Patricia B Upton; Mark W Powley; et al.

Genotoxicity of 1,3-butadiene and its epoxy intermediates.
Research report (Health Effects Institute). 2009;(144):3-79.

2
49.
2009

Narisa K. Bordeerat; Nadia I. Georgieva; David G. Klapper; Leonard B. Collins; Tyra J. Cross; Christoph H. Borchers; James A. Swenberg; Gunnar Boysen

Accurate quantitation of standard peptides used for quantitative proteomics
Proteomics. 2009;9(15):3939-3944.

12
50.
2009

George S. Bailey; Ashok P. Reddy; Clifford B. Pereira; Ulrich Harttig; William Baird; Jan M. Spitsbergen; Jerry D. Hendricks; Gayle A. Orner; David E. Williams; James A. Swenberg

Nonlinear cancer response at ultralow dose: A 40800-animal ED ₀₀₁ tumor and biomarker study
Chemical Research in Toxicology. 2009;22(7):1264-1276.

15
51.
2009

Charles R. Esther Jr.; Gunnar Boysen; Bonnie M. Olsen; Leonard B. Collins; Andrew J. Ghio; James W. Swenberg; Richard C. Boucher

Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis
American Journal of Physiology - Lung Cellular and Molecular Physiology. 2009;296(6):L987-L993.

21
52.
2009

Irene M. Baskerville-Abraham; Gunnar Boysen; J. Mitchell Troutman; Esra Mutlu; Leonard Collins; Kathryn E. DeKrafft; Wenbin Lin; Candice King; Stephen G. Chaney; James A. Swenberg

Development of an ultraperformance liquid chromatography/mass spectrometry method to quantify cisplatin 1,2 intrastrand guanine-guanine adducts
Chemical Research in Toxicology. 2009;22(5):905-912.

13
53.
2009

Kun Lu; Wenjie Ye; Avram Gold; Louise M. Ball; James A. Swenberg

Formation of S-[1 -(N ²-Deoxyguanosinyl)methyl]glutathione between Glutathione and DNA induced by formaldehyde
Journal of the American Chemical Society. 2009;131(10):3414-3415.

10
54.
2009

Melissa Goggin; James A. Swenberg; Vernon E. Walker; Natalia Tretyakova

Molecular dosimetry of 1,2,3,4-diepoxybutane - Lnduced DNA-DNA cross-links in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation
Cancer Research. 2009;69(6):2479-2486.

23
55.
2009

Dora Il'Yasova; Bridget J. McCarthy; Serap Erdal; Joanna Shimek; Jennifer Goldstein; Daniel R. Doerge; Steven R. Myers; Paolo Vineis; John S. Wishnok; James A. Swenberg; et al.

Human exposure to selected animal neurocarcinogens: A biomarker-based assessment and implications for brain tumor epidemiology
Journal of Toxicology and Environmental Health - Part B: Critical Reviews. 2009;12(3):175-187.

0
56.
2009

Dale M. Walker; Adriana E. Kajon; Salina M. Torres; Meghan M. Carter; Consuelo L. McCash; James A. Swenberg; Patricia B. Upton; Andrew W. Hardy; Ofelia A. Olivero; Gene M. Shearer; et al.

WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication
Environmental and Molecular Mutagenesis. 2009;50(6):460-472.

6
57.
2009

Samuel M. Cohen; Richard D. Storer; Kay A. Criswell; Nancy G. Doerrer; Vicki L. Dellarco; David G. Pegg; Zbigniew W. Wojcinski; David E. Malarkey; Abigail C. Jacobs; James E. Klaunig; et al.

Hemangiosarcoma in rodents: Mode-of-action evaluation and human relevance
Toxicological Sciences. 2009;111(1):4-18.

20
58.
2009

J. McKee Alderman; Kevin Flurkey; Natasha L. Brooks; Sneha B. Naik; Jonathan M. Gutierrez; Urmila Srinivas; Kristen B. Ziara; Linhong Jing; Gunnar Boysen; et al.

Neuroendocrine inhibition of glucose production and resistance to cancer in dwarf mice
Experimental Gerontology. 2009;44(1-2):26-33.

11
59.
2009

James A. Swenberg; Thomas B. Starr; Richard J. Albertini; Vernon E. Walker

Response to keshava et al. (2008)
Chemical Research in Toxicology. 2009;22(1):10-12.

2
60.
2009

Annie M. Jarabek; Lynn H. Pottenger; Larry S. Andrews; Daniel Casciano; Michelle R. Embry; James H. Kim; R. Julian Preston; M. Vijayaraj Reddy; Rita Schoeny; David Shuker; et al.

Creating context for the use of DNA adduct data in cancer risk assessment: I. Data organization
Critical Reviews in Toxicology. 2009;39(8):659-678.

19
61.
2008

M.D. Reed; E.G. Barrett; M.J. Campen; K.K. Divine; A.P. Gigliotti; J.D. McDonald; J.C. Seagrave; J.L. Mauderly; S.K. Seilkop; et al.

Health effects of subchronic inhalation exposure to gasoline engine exhaust
Inhalation Toxicology. 2008;20(13):1125-1143.

9
62.
2008

J. Michael Bishop; Douglas Hanahan; Thea Tlsty; Tony Hunter; Scott Lowe; Harold Varmus; K. Terry Dornbush; Jeffrey F. Waring; Tyler Jacks; Tona Gilmer; et al.

The 20th Aspen Cancer Conference: Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention, and Cancer Therapy 2005
Molecular Carcinogenesis. 2008;47(9):707-732.

1
63.
2008

Yo-Chan Jeong; Nigel J. Walker; Deborah E. Burgin; Grace Kissling; Mayetri Gupta; Lawrence Kupper; Linda S. Birnbaum; James A. Swenberg

Accumulation of M₁dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons
Free Radical Biology and Medicine. 2008;45(5):585-591.

13
64.
2008

Kun Lu; Gunnar Boysen; Lina Gao; Leonard B. Collins; James A. Swenberg

Formaldehyde-induced histone modifications in vitro
Chemical Research in Toxicology. 2008;21(8):1586-1593.

9
65.
2008

David Brusick; Mitchell S. Small; Ercole L. Cavalieri; Dhrubajyoti Chakravarti; Xinxin Ding; David G. Longfellow; Jun Nakamura; Eleanor C. Rogan; James A. Swenberg

Possible genotoxic modes of action for naphthalene
Regulatory Toxicology and Pharmacology. 2008;51(2 SUPLL):43-50.

11
66.
2008

B.L. Yano; J.F. Hardisty; J.C. Seely; B.E. Butterworth; E.E. McConnell; J.A. Swenberg; G.M. Williams; K.E. Stebbins; B.B. Golllapudi; et al.

Nitrapyrin: A scientific advisory group review of the mode of action and carcinogenicity in B6C3F1 mice
Regulatory Toxicology and Pharmacology. 2008;51(1):53-65.

0
67.
2008

Melissa Goggin; Chris Anderson; Soobong Park; James Swenberg; Vernon Walker; Natalia Tretyakova

Quantitative high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice
Chemical Research in Toxicology. 2008;21(5):1163-1170.

15
68.
2008

Thomas B. Starr; James Swenberg

Dose-response relationships for cancer incidence reflect susceptibility distributions
Chemical Research in Toxicology. 2008;21(5):972-973.

2
69.
2008

Matthew D. Stout; Elmarie Bodes; Robert Schoonhoven; Patricia B. Upton; Gregory S. Travlos; James A. Swenberg

Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal
Toxicologic Pathology. 2008;36(2):232-246.

6
70.
2008

Charles R. Esther Jr.; H. Matias Jasin; Leonard B. Collins; James A. Swenberg; Gunnar Boysen

A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate
Rapid Communications in Mass Spectrometry. 2008;22(5):701-705.

10
71.
2008

James A. Swenberg; Elizabeth Fryar-Tita; Yo-Chan Jeong; Gunnar Boysen; Thomas Starr; Vernon E. Walker; Richard J. Albertini

Biomarkers in toxicology and risk assessment: Informing critical dose-response relationships
Chemical Research in Toxicology. 2008;21(1):253-265.

78
72.
2007

John R. Ridpath; Ayumi Nakamura; Keizo Tano; April M. Luke; Eiichiro Sonoda; Hiroshi Arakawa; Jean-Marie Buerstedde; David A.F. Gillespie; Julian E. Sale; Mitsuyoshi Yamazoe; et al.

Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde
Cancer Research. 2007;67(23):11117-11122.

41
73.
2007

Natasha L. Brooks; Chad M. Trent; Carl F. Raetzsch; Kevin Flurkey; Gunnar Boysen; Michael T. Perfetti; Yo-Chan Jeong; Simon Klebanov; Kajal B. Patel; Valerie R. Khodush; et al.

Low utilization of circulating glucose after food withdrawal in snell dwarf mice
Journal of Biological Chemistry. 2007;282(48):35069-35077.

15
74.
2007

Courtney G. Woods; Amanda M. Burns; Blair U. Bradford; Pamela K. Ross; Oksana Kosyk; James A. Swenberg; Michael L. Cunningham; Ivan Rusyn

WY-14,643-induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase
Toxicological Sciences. 2007;98(2):366-374.

14
75.
2007

Joanne L. Watters; Jessie A. Satia; Larry L. Kupper; James A. Swenberg; Jane C. Schroeder; Boyd R. Switzer

Associations of antioxidant nutrients and oxidative DNA damage in healthy African-American and white adults
Cancer Epidemiology Biomarkers and Prevention. 2007;16(7):1428-1436.

21
76.
2007

Yibing Wu; Debadeep Bhattacharyya; Candice L. King; Irene Baskerville-Abraham; Sung-Ho Huh; Gunnar Boysen; James A. Swenberg; Brenda Temple; Sharon L. Campbell; et al.

Solution structures of a DNA dodecamer duplex with and without a cisplatin 1,2-d(GG) intrastrand cross-link: Comparison with the same DNA duplex containing an oxaliplatin 1,2-d(GG) intrastrand cross-link
Biochemistry. 2007;46(22):6477-6487.

18
77.
2007

Lynn H. Pottenger; Linda A. Malley; Matthew S. Bogdanffy; E. Maria Donner; Patricia B. Upton; Yutai Li; Vernon E. Walker; Jack R. Harkema; Marcy I. Banton; et al.

Evaluation of effects from repeated inhalation exposure of F344 rats to high concentrations of propylene
Toxicological Sciences. 2007;97(2):336-347.

6
78.
2007

Nadia I. Georgieva; Gunnar Boysen; Patricia B. Upton; Karupiah Jayaraj; Avram Gold; James A. Swenberg

Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene
Chemico-Biological Interactions. 2007;166(1-3):219-225.

4
79.
2007

Quanxin Meng; Dale M. Walker; Jake D. McDonald; Rogene F. Henderson; Meghan M. Carter; Dennis L. Cook Jr; Dennis L. Cook Jr; Consuelo L. McCash; Salina M. Torres; Michael J. Bauer; et al.

Age-, gender-, and species-dependent mutagenicity in T cells of mice and rats exposed by inhalation to 1,3-butadiene
Chemico-Biological Interactions. 2007;166(1-3):121-131.

12
80.
2007

Mark W. Powley; Vernon E. Walker; Yutai Li; Patricia B. Upton; James A. Swenberg

The importance of 3,4-epoxy-1,2-butanediol and hydroxymethylvinyl ketone in 3-butene-1,2-diol associated mutagenicity
Chemico-Biological Interactions. 2007;166(1-3):182-190.

5
81.
2007

James A. Swenberg; Gunnar Boysen; Nadia Georgieva; Michael G. Bird; R. Jeffrey Lewis

Future directions in butadiene risk assessment and the role of cross-species internal dosimetry
Chemico-Biological Interactions. 2007;166(1-3):78-83.

20
82.
2007

Richard J. Albertini; Radim J. Sram; Pamela M. Vacek; Jeremiah Lynch; Pavel Rossner; Janice A. Nicklas; Jake D. McDonald; Gunnar Boysen; Nadia Georgieva; et al.

Molecular epidemiological studies in 1,3-butadiene exposed Czech workers: Female-male comparisons
Chemico-Biological Interactions. 2007;166(1-3):63-77.

26
83.
2007

Gunnar Boysen; Nadia I. Georgieva; Patricia B. Upton; Vernon E. Walker; James A. Swenberg

N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides
Chemico-Biological Interactions. 2007;166(1-3):84-92.

16
84.
2007

Gunnar Boysen; Cameron O. Scarlett; Brenda Temple; Terry P. Combs; Natasha L. Brooks; Christoph H. Borchers; James A. Swenberg

Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro
Chemico-Biological Interactions. 2007;166(1-3):170-175.

6
85.
2007

N. Takahashi; G. Boysen; F. Li; Y. Li; J.A. Swenberg

Tandem mass spectrometry measurements of creatinine in mouse plasma and urine for determining glomerular filtration rate
Kidney International. 2007;71(3):266-271.

36
86.
2006

Paul D Chastain 2nd.; Jun Nakamura; James Swenberg; David Kaufman

Nonrandom AP site distribution in highly proliferative cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2006;20(14):2612-2614.

1
87.
2006

Paul D. Chastain II; Jun Nakamura; James Swenberg; David Kaufman

Nonrandom AP site distribution in highly proliferative cells
FASEB Journal. 2006;20(14):E2127-E2132.

9
88.
2006

J. Chadwick Roper; Denise M. Brown; Michelle A. Sullivan; Robert Schoonhoven; James A. Swenberg; Frederic K. Pfaender

Epifluorescence microscopy and image analysis of high-level polycyclic aromatic hydrocarbon contamination in soils
Environmental Toxicology and Chemistry. 2006;25(12):3093-3100.

1
89.
2006

Christine L. Powell; Oksana Kosyk; Pamela K. Ross; Robert Schoonhoven; Gunnar Boysen; James A. Swenberg; Alexandra N. Heinloth; Gary A. Boorman; Michael L. Cunningham; Richard S. Paules; et al.

Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver
Toxicological Sciences. 2006;93(1):213-222.

47
90.
2006

Matthew D. Stout; Yo-Chan Jeong; Gunnar Boysen; Yutai Li; Ramiah Sangaiah; Louise M. Ball; Avram Gold; James A. Swenberg

LC/MS/MS method for the quantitation of trans-2-hexenal-derived exocyclic 1,N²-propanodeoxyguanosine in DNA
Chemical Research in Toxicology. 2006;19(4):563-570.

7
91.
2006

Brian F. Pachkowski; Scott Winkel; Yoshiko Kubota; James A. Swenberg; Robert C. Millikan; Jim Nakamura

XRCC1 genotype and breast cancer: Functional studies and epidemiologic data show interactions between XRCC1 codon 280 his and smoking
Cancer Research. 2006;66(5):2860-2868.

50
92.
2006

Yutai Li; James T. Warren; Gunnar Boysen; Lawrence I. Gilbert; Avram Gold; Ramiah Sangaiah; Louise M. Ball; James A. Swenberg

Profiling of ecdysteroids in complex biological samples using liquid chromatography/ion trap mass spectrometry
Rapid Communications in Mass Spectrometry. 2006;20(2):185-192.

7
93.
2005

Christine L. Powell; James A. Swenberg; Ivan Rusyn

Expression of base excision DNA repair genes as a biomarker of oxidative DNA damage
Cancer Letters. 2005;229(1):1-11.

45
94.
2005

Madoka Suzuki; Yutai Li; Philip C. Smith; James A. Swenberg; David E. Martin; Susan L. Morris-Natschke; Kuo-Hsiung Lee

Anti-AIDS agents 65: Investigation of the in vitro oxidative metabolism of 3′,4′-di-O-(-)-camphanoyl-(+)-cis-khellactone derivatives as potent anti-HIV agents
Drug Metabolism and Disposition. 2005;33(11):1588-1592.

9
95.
2005

Yo-Chan Jeong; James A. Swenberg

Formation of M₁G-dR from endogenous and exogenous ROS-inducing chemicals
Free Radical Biology and Medicine. 2005;39(8):1021-1029.

15
96.
2005

Ivan Rusyn; Shoji Asakura; Yutai Li; Oksana Kosyk; Hasan Koc; Jun Nakamura; Patricia B. Upton; James A. Swenberg

Effects of ethylene oxide and ethylene inhalation on DNA adducts, apurinic/apyrimidinic sites and expression of base excision DNA repair genes in rat brain, spleen, and liver
DNA Repair. 2005;4(10):1099-1110.

17
97.
2005

M.W. Powley; Y. Li; P.B. Upton; V.E. Walker; James A. Swenberg

Quantification of DNA and hemoglobin adducts of 3,4-epoxy-1,2-butanediol in rodents exposed to 3-butene-1,2-diol
Carcinogenesis. 2005;26(9):1573-1580.

20
98.
2005

Brenda K. Weis; David Balshaw; John R. Barr; David Brown; Mark Ellisman; Paul Lioy; Gilbert Omenn; John D. Potter; Martyn T. Smith; Lydia Sohn; et al.

Personalized exposure assessment: Promising approaches for human environmental health research
Environmental Health Perspectives. 2005;113(7):840-848.

52
99.
2005

Theodore Bammler; Richard P. Beyer; Sanchita Bhattacharya; Gary A. Boorman; Abee Boyles; Blair U. Bradford; Roger E. Bumgarner; Pierre R. Bushel; Kabir Chaturvedi; Dongseok Choi; et al.

Standardizing global gene expression analysis between laboratories and across platforms
Nature Methods. 2005;2(5):1-6.

29
100.
2005

Theodore Bammler; Richard P Beyer; Sanchita Bhattacharya; Gary A Boorman; Abee Boyles; Blair U Bradford; Roger E Bumgarner; Pierre R Bushel; Kabir Chaturvedi; Dongseok Choi; et al.

Standardizing global gene expression analysis between laboratories and across platforms.
Nat Methods. 2005;2(5):351-356.

257
101.
2005

Kevin S. McDorman; Brian F. Pachkowski; Jun Nakamura; Douglas C. Wolf; James A. Swenberg

Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products
Chemico-Biological Interactions. 2005;152(2-3):107-117.

9
102.
2005

Chia-Hua Lin; Hong-Tsee Leow; Shih-Chien Huang; Jun Nakamura; James A. Swenberg; Po-Hsiung Lin

Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells
Chemical Research in Toxicology. 2005;18(2):257-264.

14
103.
2005

Yo-Chan Jeong; Ramiah Sangaiah; Jun Nakamura; Brian F. Pachkowski; Asoka Ranasinghe; Avram Gold; Louise M. Ball; James A. Swenberg

Analysis of M₁G-dR in DNA by aldehyde reactive probe labeling and liquid chromatography tandem mass spectrometry
Chemical Research in Toxicology. 2005;18(1):51-60.

20
104.
2005

Moung S. Lee; Thomas H. Faller; Paul E. Kreuzer; Winfried Kessler; György A. Csanády; Christian Pütz; Melva N. Ríos-Blanco; Lynn H. Pottenger; Dan Segerbäck; et al.

Propylene oxide in blood and soluble nonprotein thiols in nasal mucosa and other tissues of male Fischer 344/N rats exposed to propylene oxide vapors - Relevance of glutathione depletion for propylene oxide-induced rat nasal tumors
Toxicological Sciences. 2005;83(1):177-189.

15
105.
2005

Su-Yin Chiang; Tai-Hung Huang; Shi-Nian Uang; Hong-Dar Isaac Wu; Yi-Chiech Wei; Hui-Yi Lin; James A. Swenberg; Kuen-Yuh Wu

Analysis of 7-methylguanine using isotope dilution and gas chromatography/electron-capture negative chemical ionization mass spectrometry
Rapid Communications in Mass Spectrometry. 2005;19(14):1915-1920.

4
106.
2005

Yo-Chan Jeong; Jun Nakamura; Patricia B. Upton; James A. Swenberg

Pyrimido[1,2-a]-purin-10(3H)-one, M₁G, is less prone to artifact than base oxidation
Nucleic Acids Research. 2005;33(19):6426-6434.

22
107.
2004

William Slikker Jr.; Melvin E. Andersen; Matthew S. Bogdanffy; James S. Bus; Steven D. Cohen; Rory B. Conolly; Raymond M. David; Nancy G. Doerrer; David C. Dorman; David W. Gaylor; et al.

Dose-dependent transitions in mechanisms of toxicity: Case studies
Toxicology and Applied Pharmacology. 2004;201(3):226-294.

73
108.
2004

William Slikker Jr.; Melvin E. Andersen; Matthew S. Bogdanffy; James S. Bus; Steven D. Cohen; Rory B. Conolly; Raymond M. David; Nancy G. Doerrer; David C. Dorman; David W. Gaylor; et al.

Dose-dependent transitions in mechanisms of toxicity
Toxicology and Applied Pharmacology. 2004;201(3):203-225.

62
109.
2004

Gunnar Boysen; Nadia I. Georgieva; Patricia B. Upton; Karupiah Jayaraj; Yutai Li; Vernon E. Walker; James A. Swenberg

Analysis of diepoxide-specific cyclic N-terminal globin adducts in mice and rats after inhalation exposure to 1,3-butadiene
Cancer Research. 2004;64(23):8517-8520.

33
110.
2004

Lilian Calderón-Garcidueñas; William Reed; Robert R. Maronpot; Carlos Henríquez-Roldán; Ricardo Delgado-Chavez; Ana Calderón-Garcidueñas; Irma Dragustinovis; Maricela Franco-Lira; Mariana Aragón-Flores; et al.

Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution
Toxicologic Pathology. 2004;32(6):650-658.

90
111.
2004

Po-Hsiung Lin; R. Sangaiah; Asoka Ranasinghe; Louise M. Ball; James A. Swenberg; Avram Gold

Synthesis of chlorinated and non-chlorinated biphenyl-2,3- and 3,4-catechols and their [ ²H ₃]-isotopomers
Organic and Biomolecular Chemistry. 2004;2(18):2624-2629.

5
112.
2004

Joanna Zielinska-Park; Jun Nakamura; James A. Swenberg; Michael D. Aitken

Aldehydic DNA lesions in calf thymus DNA and HeLa S3 cells produced by bacterial quinone metabolites of fluoranthene and pyrene
Carcinogenesis. 2004;25(9):1727-1733.

17
113.
2004

Yibing Wu; Padmanava Pradhan; Jody Havener; Gunnar Boysen; James A. Swenberg; Sharon L. Campbell; Stephen G. Chaney

NMR solution structure of an oxaliplatin 1,2-d(GG) intrastrand cross-link in a DNA dodecamer duplex
Journal of Molecular Biology. 2004;341(5):1251-1269.

29
114.
2004

Petra Begemann; Nadia I. Christova-Georgieva; Ramiah Sangaiah; Hasan Koc; Daping Zhang; Bernard T. Golding; Avram Gold; James A. Swenberg

Synthesis, characterization, and identification of N7-guanine adducts of isoprene monoepoxides in vitro
Chemical Research in Toxicology. 2004;17(7):929-936.

10
115.
2004

Amy-Joan L. Ham; Bevin P. Engelward; Hasan Koc; Ramiah Sangaiah; Lisiane B. Meira; Leona D. Samson; James A. Swenberg

New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N⁶-etheno-deoxyadenosine DNA lesions from lung and liver in vivo
DNA Repair. 2004;3(3):257-265.

21
116.
2004

Ivan Rusyn; Shoji Asakura; Brian Pachkowski; Blair U. Bradford; Mikhail F. Denissenko; Jeffrey M. Peters; Steven M. Holland; Janardan K. Reddy; Michael L. Cunningham; et al.

Expression of Base Excision DNA Repair Genes Is a Sensitive Biomarker for in Vivo Detection of Chemical-induced Chronic Oxidative Stress: Identification of the Molecular Source of Radicals Responsible for DNA Damage by Peroxisome Proliferators
Cancer Research. 2004;64(3):1050-1057.

56
117.
2004

James A Swenberg

Toxicological considerations in the application and interpretation of DNA adducts in epidemiological studies.
IARC scientific publications. 2004;(157):237-246.

7
118.
2004

Chiung-Wen Hu; Ming-Tsang Wu; Mu-Rong Chao; Chih-Hong Pan; Chien-Jen Wang; James A. Swenberg; Kuen-Yuh Wu

Comparison of analyses of urinary 8-hydroxy-2′-deoxyguanosine by isotope-dilution liquid chromatography with electrospray tandem mass spectrometry and by enzyme-linked immunosorbent assay
Rapid Communications in Mass Spectrometry. 2004;18(4):505-510.

63
119.
2004

Li-Xuan Qin; Kathleen F. Kerr; Abee Boyles; Holly K. Dressman; Jonathan H. Freedman; Y.-Ju Li; Renae L. Malek; David A. Schwartz; Susan Slifer; Mary C. Speer; et al.

Empirical evaluation of data transformations and ranking statistics for microarray analysis
Nucleic Acids Research. 2004;32(18):5471-5479.

54
120.
2003

Mark W. Powley; Karupiah Jayaraj; Avram Gold; Louise M. Ball; James A. Swenberg

1,N²-Propanodeoxyguanosine Adducts of the 1,3-Butadiene Metabolite, Hydroxymethylvinyl Ketone
Chemical Research in Toxicology. 2003;16(11):1448-1454.

18
121.
2003

Alain Barbin; Hiroko Ohgaki; Jun Nakamura; Michael Kurrer; Paul Kleihues; James A. Swenberg

Endogenous Deoxyribonucleic Acid (DNA) Damage in Human Tissues: A Comparison of Ethenobases with Aldehydic DNA Lesions
Cancer Epidemiology Biomarkers and Prevention. 2003;12(11 II):1241-1247.

18
122.
2003

Melva N. Ríos-Blanco; Shuji Yamaguchi; Mukta Dhawan-Robl; Winfried Kessler; Robert Schoonhoven; Johannes G. Filser; James A. Swenberg

Effects of propylene oxide exposure on rat nasal respiratory cell proliferation
Toxicological Sciences. 2003;75(2):279-288.

9
123.
2003

Lilian Calderón-Garcidueñas; Robert R. Maronpot; Ricardo Torres-Jardon; Carlos Henríquez-Roldán; Robert Schoonhoven; Hilda Acuña-Ayala; Anna Villarreal-Calderón; Jun Nakamura; Reshan Fernando; William Reed; et al.

DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration
Toxicologic Pathology. 2003;31(5):524-538.

67
124.
2003

Jun Nakamura; Shoji Asakura; Susan D Hester; Gilbert de Murcia; Keith W Caldecott; James A Swenberg

Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time.
Nucleic acids research. 2003;31(17):e104.

43
125.
2003

Melva N. Ríos-Blanco; Asoka Ranasinghe; Moung S. Lee; Thomas Faller; Johannes G. Filser; James A. Swenberg

Molecular dosimetry of N7-(2-hydroxypropyl)guanine in tissues of F344 rats after inhalation exposure to propylene oxide
Carcinogenesis. 2003;24(7):1233-1238.

15
126.
2003

Richard J Albertini; Radim J Srám; Pamela M Vacek; Jeremiah Lynch; Janice A Nicklas; Nico J van Sittert; Peter J Boogaard; Rogene F Henderson; James A Swenberg; A.D. Tates; et al.

Biomarkers in Czech workers exposed to 1,3-butadiene: a transitional epidemiologic study.
Research report (Health Effects Institute). 2003;(116):1-141; discussion 143.

12
127.
2003

Po-Hsiung Lin; Jun Nakamura; Shuji Yamaguchi; Shoji Asakura; James A. Swenberg

Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA
Carcinogenesis. 2003;24(6):1133-1141.

27
128.
2003

K. Jayaraj; Nadia I. Georgieva; Avram Gold; R. Sangaiah; Hasan Koc; David G. Klapper; Louise M. Ball; Anantha P. Reddy; James A. Swenberg

Synthesis and characterization of peptides containing a cyclic val adduct of diepoxybutane, a possible biomarker of human exposure to butadiene
Chemical Research in Toxicology. 2003;16(5):637-643.

10
129.
2003

Jun Nakamura; Elizabeth R. Purvis; James A. Swenberg

Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells
Nucleic Acids Research. 2003;31(6):1790-1795.

28
130.
2003

Richard Albertini; Harvey Clewell; Matthew W. Himmelstein; Eric Morinello; Stephen Olin; Julian Preston; Louis Scarano; Martyn T. Smith; James Swenberg; Raymond Tice; et al.

The use of non-tumor data in cancer risk assessment: Reflections on butadiene, vinyl chloride, and benzene
Regulatory Toxicology and Pharmacology. 2003;37(1):105-132.

43
131.
2003

Julie K. Horton; Donna F. Joyce-Gray; Brian F. Pachkowski; James A. Swenberg; Samuel H. Wilson

Hypersensitivity of DNA polymerase β null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions
DNA Repair. 2003;2(1):27-48.

55
132.
2003

David E. Williams; George S. Bailey; Ashok Reddy; Jerry D. Hendricks; Aram Oganesian; Gayle A. Orner; Cliff B. Pereira; James A. Swenberg

The rainbow trout (Oncorhynchus mykiss) tumor model: Recent applications in low-dose exposures to tumor initiators and promoters
Toxicologic Pathology. 2003;31(SUPPL.):58-61.

24
133.
2002

Melva N. Ríos-Blanco; Asoka Ranasinghe; Patricia Upton; Moung S. Lee; Johannes G. Filser; James A. Swenberg

Exposure-dependent accumulation of N-(2-hydroxypropyl)valine in hemoglobin of F344 rats exposed to propylene oxide by the inhalation route
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2002;778(1-2):383-391.

9
134.
2002

Hasan Koc; James A. Swenberg

Applications of mass spectrometry for quantitation of DNA adducts
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2002;778(1-2):323-343.

80
135.
2002

James A. Swenberg; Nadia Gorgeiva; Amy Ham; Hasan Koc; Eric Morinello; Asoka Ranasinghe; Patricia Upton; Vernon Walker

Linking pharmacokinetics and biomarker data to mechanism of action in risk assessment
Human and Ecological Risk Assessment. 2002;8(6):1315-1338.

1
136.
2002

Silvia Fustinoni; Leonardo Soleo; Margareta Warholm; Petra Begemann; Agneta Rannug; Hans-G. Neumann; James A. Swenberg; Luigi Vimercati; Vito Foà; et al.

Influence of metabolic genotypes on biomarkers of exposure to 1,3-butadiene in humans
Cancer Epidemiology Biomarkers and Prevention. 2002;11(10 I):1082-1090.

33
137.
2002

Mark Toraason; Mel Andersen; Matthew S. Bogdanffy; David Dankovic; Elaine Faustman; Paul Foster; Clay Frederick; Lynne Haber; Carole A. Kimmel; Steven Lewis; et al.

Improving risk assessment: Toxicological research needs
Human and Ecological Risk Assessment. 2002;8(6):1405-1419.

3
138.
2002

Eric J. Morinello; Amy-Joan L. Ham; Asoka Ranasinghe; Jun Nakamura; Patricia B. Upton; James A. Swenberg

Molecular dosimetry and repair of N²,3-ethenoguanine in rats exposed to vinyl chloride
Cancer Research. 2002;62(18):5189-5195.

27
139.
2002

Hasan Koc; Mei-Heng Mar; Asoka Ranasinghe; James A. Swenberg; Steven H. Zeisel

Quantitation of choline and its metabolites in tissues and foods by liquid chromatography/electrospray ionization-isotope dilution mass spectrometry
Analytical Chemistry. 2002;74(18):4734-4740.

117
140.
2002

Eric J. Morinello; Hasan Koc; Asoka Ranasinghe; James A. Swenberg

Differential induction of N²,3-ethenoguanine in rat brain and liver after exposure to vinyl chloride
Cancer Research. 2002;62(18):5183-5188.

15
141.
2002

James A Swenberg; Amy-Joan L Ham; Kevin S McDorman; Eric J Morinello; Jun Nakamura; Robert Schoonhoven

Methods for measuring DNA adducts and abasic sites I: isolation, purification, and analysis of DNA adducts in intact DNA.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.]. 2002;Chapter 3:Unit3.8.

0
142.
2002

James A Swenberg; Amy-Joan L Ham; Hasan Koc; David K La; Eric J Morinello; Brian F Pachkowski; Asoka Ranasinghe; Patricia B Upton

Methods for measuring DNA adducts and abasic sites II: methods for measurement of DNA adducts.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.]. 2002;Chapter 3:Unit3.9.

0
143.
2002

Robert W. Sobol; David E. Watson; Jun Nakamura; F. Michael Yakes; Esther Hou; Julie K. Horton; Joseph Ladapo; Bennett Van Houten; James A. Swenberg; Kenneth R. Tindall; et al.

Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress
Proceedings of the National Academy of Sciences of the United States of America. 2002;99(10):6860-6865.

50
144.
2002

Peter B. Farmer; Helmut Bartsch; Alan Boobis; Kevin Chipman; Andy Gescher; Fred F. Kadlubar; Margaret M. Manson; David H. Phillips; David E. G. Shuker; James A. Swenberg; et al.

Basic or applied, it's the interaction that counts [1]
Nature. 2002;417(6885):117.

0
145.
2002

Frank C. Richardson; Chenghong Zhang; S. Russ Lehrman; Hasan Koc; James A. Swenberg; Katherine A. Richardson; Raymond A. Bendele

Quantification of 2′-fluoro-2′-deoxyuridine and 2′-fluoro-2′-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS
Chemical Research in Toxicology. 2002;15(7):922-926.

17
146.
2002

Po-Hsiung Lin; David K. La; Patricia B. Upton; James A. Swenberg

Analysis of DNA adducts in rats exposed to pentachlorophenol
Carcinogenesis. 2002;23(2):365-369.

25
147.
2001

R.B. Hayes; L. Zhang; J.A. Swenberg; S.-N. Yin; L. Xi; J. Wiencke; W.E. Bechtold; M. Yao; N. Rothman; R. Haas; et al.

Markers for carcinogenicity among butadiene-polymer workers in China
Chemico-Biological Interactions. 2001;135-136:455-464.

17
148.
2001

Quanxin Meng; Rogene F. Henderson; Lingyan Long; Lee Blair; Dale M. Walker; Patricia B. Upton; James A. Swenberg; Vernon E. Walker

Mutagenicity at the Hprt locus in T cells of female mice following inhalation exposures to low levels of 1,3-butadiene
Chemico-Biological Interactions. 2001;135-136:343-361.

17
149.
2001

James A. Swenberg; Hasan Koc; Patricia B. Upton; Nadia Georguieva; Asoka Ranasinghe; Vernon E. Walker; Rogene Henderson

Using DNA and hemoglobin adducts to improve the risk assessment of butadiene
Chemico-Biological Interactions. 2001;135-136:387-403.

38
150.
2001

Richard J. Albertini; Radim J. Sram; Pamela M. Vacek; Jeremiah Lynch; Michael Wright; Janice A. Nicklas; Peter J. Boogaard; Rogene F. Henderson; James A. Swenberg; A.D. Tates; et al.

Biomarkers for assessing occupational exposures to 1,3-butadiene
Chemico-Biological Interactions. 2001;135-136:429-453.

45
151.
2001

Petra Begemann; Patricia B. Upton; Asoka Ranasinghe; James A. Swenberg; Leonardo Soleo; Luigi Vimercati; Alfonso Gelormini; Silvia Fustinoni; Iris Zwirner-Baier; et al.

Hemoglobin adducts as biomarkers of 1,3-butadiene in occupationally low exposed Italian workers and a few diesel-exposed miners
Chemico-Biological Interactions. 2001;135-136:675-678.

11
152.
2001

James M. McKim Jr.; Gary B. Kolesar; Paul A. Jean; Linda S. Meeker; Paul C. Wilga; Robert Schoonhoven; James A. Swenberg; Jay I. Goodman; Robert H. Gallavan; Robert G. Meeks

Repeated inhalation exposure to octamethylcyclotetrasiloxane produces hepatomegaly, transient hepatic hyperplasia, and sustained hypertrophy in female Fischer 344 rats in a manner similar to phenobarbital
Toxicology and Applied Pharmacology. 2001;172(2):83-92.

17
153.
2001

M. Yin; M.D. Wheeler; H.D. Connor; Z. Zhong; H. Bunzendahl; A. Dikalova; R.J. Samulski; R. Schoonhoven; R.P. Mason; J.A. Swenberg; et al.

Cu/Zn-superoxide dismutase gene attenuates ischemia-reperfusion injury in the rat kidney
Journal of the American Society of Nephrology. 2001;12(12):2691-2700.

46
154.
2001

Po-Hsiung Lin; Jun Nakamura; Shuji Yamaguchi; Patricia B. Upton; David K. La; James A. Swenberg

Oxidative damage and direct adducts in calf thymus DNA induced by the pentachlorophenol metabolities, tetrachlorohydroquinone and tetrachloro-1, 4-benzoquinone
Carcinogenesis. 2001;22(4):627-634.

38
155.
2001

Po-Hsiung Lin; Jun Nakamura; Shuji Yamaguchi; David K. La; Patricia B. Upton; James A. Swenberg

Induction of direct adducts, apurinic/apyrimidinic sites and oxidized bases in nuclear DNA of human HeLa S3 tumor cells by tetrachlorohydroquinone
Carcinogenesis. 2001;22(4):635-639.

26
156.
2001

E.J. Morinello; A.-J.L. Ham; A. Ranasinghe; R. Sangaiah; J.A. Swenberg

Simultaneous quantitation of N²,3-ethenoguanine and 1,N²-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay
Chemical Research in Toxicology. 2001;14(3):327-334.

37
157.
2000

I. Rusyn; S. Yamashina; B.H. Segal; R. Schoonhoven; S.M. Holland; R.C. Cattley; J.A. Swenberg; R.G. Thurman

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators
Cancer Research. 2000;60(17):4798-4803.

34
158.
2000

S. Holt; G. Roy; S. Mitra; P.B. Upton; M.S. Bogdanffy; J.A. Swenberg

Deficiency of N-methylpurine-DNA-glycosylase expression in nonparenchymal cells, the target cell for vinyl chloride and vinyl fluoride
Mutation Research - DNA Repair. 2000;460(2):105-115.

14
159.
2000

S. Perwez Hussain; Paul Amstad; Kamran Raja; Stefan Ambs; Makoto Nagashima; William P. Bennett; Peter G. Shields; Amy-Joan Ham; James A. Swenberg; Aizen J. Marrogi; et al.

Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: A cancer-prone chronic inflammatory disease
Cancer Research. 2000;60(13):3333-3337.

227
160.
2000

Ming Yin; Ivan Rusyn; Robert Schoonhoven; Lee M. Graves; Elena V. Rusyn; Xiangli Li; Fengling Li; Adrienne D. Cox; Tim W. Harding; Hartwig Bunzendahl; et al.

Inhibition of chronic rejection of aortic allografts by dietary glycine
Transplantation. 2000;69(5):773-780.

9
161.
2000

J.A. Swenberg; N.I. Christova-Gueorguieva; P.B. Upton; A. Ranasinghe; N. Scheller; K.Y. Wu; T.Y. Yen; R. Hayes

1,3-butadiene: cancer, mutations, and adducts. Part V: Hemoglobin adducts as biomarkers of 1,3-butadiene exposure and metabolism.
Research report (Health Effects Institute). 2000;(92):191-210; discussion 211.

6
162.
2000

Jun Nakamura; David K. La; James A. Swenberg

5'-Nicked apurinic/apyrimidinic sites are resistant to β-elimination by β-polymerase and are persistent in human cultured cells after oxidative stress
Journal of Biological Chemistry. 2000;275(8):5323-5328.

75
163.
2000

Sandra Boivin-Angèle; Lydie Lefrançois; Olivier Froment; Andreas Spiethoff; Matthew S. Bogdanffy; Kurt Wegener; Horst Wesch; Alain Barbin; Brigitte Bancel; et al.

Ras gene mutations in vinyl chloride-induced liver tumours are carcinogen-specific but vary with cell type and species
International Journal of Cancer. 2000;85(2):223-227.

28
164.
2000

James A. Swenberg; Amy Ham; Hasan Koc; Eric Morinello; Asoka Ranasinghe; Natalia Tretyakova; Patricia B. Upton; Kuen-Yuh Wu

DNA adducts: Effects of low exposure to ethylene oxide, vinyl chloride and butadiene
Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 2000;464(1):77-86.

28
165.
2000

R.B. Hayes; L. Zhang; S. Yin; J.A. Swenberg; L. Xi; J. Wiencke; W.E. Bechtold; M. Yao; N. Rothman; R. Haas; et al.

Genotoxic markers among butadiene polymer workers in China
Carcinogenesis. 2000;21(1):55-62.

61
166.
2000

Melva N. Ríos-Blanco; Thomas H. Faller; Jun Nakamura; Winfried Kessler; Paul E. Kreuzer; Asoka Ranasinghe; Johannes G. Filser; James A. Swenberg

Quantitation of DNA and hemoglobin adducts and apurinic/apyrimidinic sites in tissues of F344 rats exposed to propylene oxide by inhalation
Carcinogenesis. 2000;21(11):2011-2018.

22
167.
2000

P.-H. Lin; R. Sangaiah; A. Ranasinghe; P.B. Upton; D.K. La; A. Gold; J.A. Swenberg

Formation of quinonoid-derived protein adducts in the liver and brain of Sprague-Dawley rats treated with 2,2',5,5'-tetrachlorobiphenyl
Chemical Research in Toxicology. 2000;13(8):710-718.

16
168.
2000

Vernon E. Walker; Kuen-Yuh Wu; Patricia B. Upton; Asoka Ranasinghe; Nova Scheller; Myung-Haeng Cho; Jane S. Vergnes; Thomas R. Skopek; James A. Swenberg

Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide
Carcinogenesis. 2000;21(9):1661-1669.

37
169.
2000

Amy-Joan L. Ham; Asoka Ranasinghe; Hasan Koc; James A. Swenberg

4-Hydroxy-2-nonenal and ethyl linoleate form N²,3-ethenoguanine under peroxidizing conditions
Chemical Research in Toxicology. 2000;13(12):1243-1250.

27
170.
2000

Ivan Rusyn; Mikhail F. Denissenko; Victoria A. Wong; Byron E. Butterworth; Michael L. Cunningham; Patricia B. Upton; Ronald G. Thurman; James A. Swenberg

Expression of base excision repair enzymes in rat and mouse liver is induced by peroxisome proliferators and is dependent upon carcinogenic potency
Carcinogenesis. 2000;21(12):2141-2145.

42
171.
1999

Ingvar Eide; Chunyan Zhao; Rajiv Kumar; Kari Hemminki; Kuen-Yu Wu; James A. Swenberg

Comparison of ³²P-postlabeling and high-resolution GC/MS in quantifying N7-(2-hydroxyethyl)guanine adducts
Chemical Research in Toxicology. 1999;12(10):979-984.

17
172.
1999

Peter Schemmer; Robert Schoonhoven; James A. Swenberg; Hartwig Bunzendahl; James A. Raleigh; John J. Lemasters; Ronald G. Thurman

Gentle organ manipulation during harvest as a key determinant of survival of fatty livers after transplantation in the rat
Transplant International. 1999;12(5):351-359.

27
173.
1999

John Doull; Russell Cattley; Cliff Elcombe; Brian G. Lake; James Swenberg; Christopher Wilkinson; Gary Williams; Marcia Van Gemert

A cancer risk assessment of di(2-ethylhexyl)phthalate: Application of the new U.S. EPA risk assessment guidelines
Regulatory Toxicology and Pharmacology. 1999;29(3):327-357.

163
174.
1999

Jun Nakamura; James A. Swenberg

Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues
Cancer Research. 1999;59(11):2522-2526.

185
175.
1999

J.A. Swenberg; M.S. Bogdanffy; A. Ham; S. Holt; A. Kim; E.J. Morinello; A. Ranasinghe; N. Scheller; P.B. Upton

Formation and repair of DNA adducts in vinyl chloride- and vinyl fluoride-induced carcinogenesis.
IARC scientific publications. 1999;(150):29-43.

14
176.
1999

Amy-Joan L. Ham; Asoka Ranasinghe; Eric J. Morinello; Jun Nakamura; Patricia B. Upton; Francis Johnson; James A. Swenberg

Immunoaffinity/gas chromatography/high-resolution mass spectrometry method for the detection of N²,3-ethenoguanine
Chemical Research in Toxicology. 1999;12(12):1240-1246.

34
177.
1999

Kuen-Yuh Wu; Nova Scheller; Asoka Ranasinghe; Ten-Yang Yen; Ramiah Sangaiah; Roger Giese; James A. Swenberg

A gas chromatography/electron capture/negative chemical ionization high- resolution mass spectrometry method for analysis of endogenous and exogenous N7-(2-hydroxyethyl)guanine in rodents and its potential for human biological monitoring
Chemical Research in Toxicology. 1999;12(8):722-729.

36
178.
1999

Koc Hasan; Natalia Y. Tretyakova; Vernon E. Walker; Rogene F. Henderson; James A. Swenberg

Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene
Chemical Research in Toxicology. 1999;12(7):566-574.

69
179.
1999

Kuen-Yuh Wu; Asoka Ranasinghe; Patricia B. Upton; Vernon E. Walker; James A. Swenberg

Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents
Carcinogenesis. 1999;20(9):1787-1792.

26
180.
1999

Michelle L. Rose; Chantal A. Rivera; Blair U. Bradford; Lee M. Graves; Russell C. Cattley; Robert Schoonhoven; James A. Swenberg; Ronald G. Thurman

Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators
Carcinogenesis. 1999;20(1):27-33.

56
181.
1999

Po-Hsiung Lin; Suramya Waidyanatha; Gary M. Pollack; James A. Swenberg; Stephen M. Rappaport

Dose-specific production of chlorinated quinone and semiquinone adducts in rodent livers following administration of pentachlorophenol
Toxicological Sciences. 1999;47(1):126-133.

15
182.
1999

J.A. Swenberg; L.D. Lehman-McKeeman

alpha 2-Urinary globulin-associated nephropathy as a mechanism of renal tubule cell carcinogenesis in male rats.
IARC scientific publications. 1999;(147):95-118.

12
183.
1999

Ivan Rusyn; Cynthia A. Bradham; Leslie Cohn; Robert Schoonhoven; James A. Swenberg; David A. Brenner; Ronald G. Thurman

Corn oil rapidly activates nuclear factor-κB in hepatic Kupffer cells by oxidant-dependent mechanisms
Carcinogenesis. 1999;20(11):2095-2100.

21
184.
1999

Sophia S. Wang; J. Patrick O'Neill; Geng-Sun Qian; Yu-Rong Zhu; Jia-Bin Wang; Haroutune Armenian; Audrey Zarba; Jia-Sheng Wang; Thomas W. Kensler; Neal F. Cariello; et al.

Elevated HPRT mutation frequencies in aflatoxin-exposed residents of Daxin, Qidong County, People's Republic of China
Carcinogenesis. 1999;20(11):2181-2184.

3
185.
1998

S. Holt; T.-Y. Yen; R. Sangaiah; J.A. Swenberg

Detection of 1,N⁶-ethenoadenine in rat urine after chloroethylene oxide exposure
Carcinogenesis. 1998;19(10):1763-1769.

16
186.
1998

Peter Schemmer; Robert Schoonhoven; James A. Swenberg; Hartwig Bunzendahl; Ronald G. Thurman

Gentle in situ liver manipulation during organ harvest decreases survival after rat liver transplantation: Role of Kupffer cells
Transplantation. 1998;65(8):1015-1020.

75
187.
1998

Natalia Yu. Tretyakova; Su-Yin Chiang; Vernon E. Walker; James A. Swenberg

Quantitative analysis of 1,3-butadiene-induced DNA adducts in vivo and in vitro using liquid chromatography electrospray ionization tandem mass spectrometry
Journal of Mass Spectrometry. 1998;33(4):363-376.

56
188.
1998

J. McHugh Law; Marta Bull; Jun Nakamura; James A. Swenberg

Molecular dosimetry of DNA adducts in the medaka small fish model
Carcinogenesis. 1998;19(3):515-518.

12
189.
1998

Jun Nakamura; Vernon E. Walker; Patricia B. Upton; Su-Yin Chiang; Yoke W. Kow; James A. Swenberg

Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions
Cancer Research. 1998;58(2):222-225.

156
190.
1998

Asoka Ranasinghe; Nova Scheller; Kuen Y. Wu; Patricia B. Upton; James A. Swenberg

Application of gas chromatography/electron capture negative chemical ionization high-resolution mass spectrometry for analysis of DNA and protein adducts
Chemical Research in Toxicology. 1998;11(5):520-526.

14
191.
1998

R.A. Roberts; I. Purchase; T. Green; J. Parry; J. Swenberg; J. Evans; B. Cox; J. Ashby; I. Kimber; B. Farland

Zenca Central Toxicoloty Laboratory (CTL) seminar, Alderley Park, Cheshire, UK, 26-27 January 1998: The scientific and practical basis for thresholds in biology
Human and Experimental Toxicology. 1998;17(5):278-282.

1
192.
1998

Ten-Yang Yen; Sharon Holt; Ramiah Sangaiah; Avram Gold; James A. Swenberg

Quantitation of 1,N⁶-ethenoadenine in rat urine by immunoaffinity extraction combined with liquid chromatography/electrospray ionization mass spectrometry
Chemical Research in Toxicology. 1998;11(7):810-815.

20
193.
1997

Melva N. Ríos-Blanco; Kamila Plna; Thomas Faller; Winfried Kessler; Krystyna Håkansson; Paul E. Kreuzer; Asoka Ranasinghe; Johannes G. Filser; Dan Segerbäck; et al.

Propylene oxide: Mutagenesis, carcinogenesis and molecular dose
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1997;380(1-2):179-197.

33
194.
1997

Natalia Tretyakova; Ramiah Sangaiah; Ten-Yang Yen; Avram Gold; James A. Swenberg

Adenine adducts with diepoxybutane: Isolation and analysis in exposed calf thymus DNA
Chemical Research in Toxicology. 1997;10(10):1171-1179.

47
195.
1997

R. Sangaiah; N.I. Christova-Gueorguieva; A. Ranasinghe; N.Yu. Tretyakova; A. Gold; L.M. Ball; J.A. Swenberg

Synthesis of perdeuterated analogues of the epoxide metabolites of butadiene: 1,2-epoxybut-3-ene-d₆ and 1,2,3,4-diepoxybutane-d₆
Journal of Labelled Compounds and Radiopharmaceuticals. 1997;39(9):731-739.

2
196.
1997

Natalia Yu. Tretyakova; Ramiah Sangaiah; Ten-Yang Yen; James A. Swenberg

Synthesis, characterization, and in vitro quantitation of N-7-guanine adducts of diepoxybutane
Chemical Research in Toxicology. 1997;10(7):779-785.

53
197.
1997

J.A. Foran; W.T. Allaben; J. Ashby; R. Bass; J.R. Bucher; W. Burnam; J.S. Bus; B.E. Butterworth; M. Carakostas; J. Emerson; et al.

Principles for the selection of doses in chronic rodent bioassays
Environmental Health Perspectives. 1997;105(1):18-20.

8
198.
1997

James A. Swenberg; Robert O. Beauchamp Jr.

A review of the chronic toxicity, carcinogenicity, and possible mechanisms of action of inorganic acid mists in animals
Critical Reviews in Toxicology. 1997;27(3):253-259.

6
199.
1997

D. Paustenbach; Y. Alarie; T. Kulle; N. Schachter; R. Smith; J. Swenberg; H. Witschi; S.B. Horowitz

A recommended occupational exposure limit for formaldehyde based on irritation
Journal of Toxicology and Environmental Health. 1997;50(3):217-263.

50
200.
1997

Su-Yin Chiang; James A. Swenberg; Wade H. Weisman; Thomas R. Skopek

Mutagenicitg of vinyl chloride and its reactive metabolites, chloroethylene oxide and chloroacetaldehyde, in a metabolically competent human B-lymphoblastoid line
Carcinogenesis. 1997;18(1):31-36.

24
201.
1997

James A. Swenberg

Clinical relevance of laboratory and animal data on tamoxifen
ONCOLOGY. 1997;11(2 SUPPL. 1):39-44.

9
202.
1997

Natalia Tretyakova; Yu-Pang Lin; Ramiah Sangaiah; Patricia B. Upton; James A. Swenberg

Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene
Carcinogenesis. 1997;18(1):137-147.

46
203.
1996

Ten-Yang Yen; Nadia I. Christova-Gueoguieva; Nova Scheller; Sharon Holt; James A. Swenberg; M. Judith Charles

Quantitative analysis of the DNA adduct N²,3-ethenoguanine using liquid chromatography/electrospray ionization mass spectrometry
Journal of Mass Spectrometry. 1996;31(11):1271-1276.

44
204.
1996

Natalia Yu. Tretyakova; Yu-Pang Lin; Patricia B. Upton; Ramiah Sangaiah; James A. Swenberg

Macromolecular adducts of butadiene
Toxicology. 1996;113(1-3):70-76.

34
205.
1996

David K. La; Robert Schoonhoven; Norio Ito; James A. Swenberg

The effects of exposure route on DNA adduct formation and cellular proliferation by 1,2,3-Trichloropropane
Toxicology and Applied Pharmacology. 1996;140(1):108-114.

10
206.
1996

David K. La; James A. Swenberg

DNA adducts: Biological markers of exposure and potential applications to risk assessment
Mutation Research - Reviews in Genetic Toxicology. 1996;365(1-3):129-146.

88
207.
1996

Thomas M. Monticello; James A. Swenberg; Elizabeth A. Gross; Joel R. Leininger; Julia S. Kimbell; Steve Seilkop; Thomas B. Starr; James E. Gibson; Kevin T. Morgan

Correlation of regional and nonlinear formaldehyde-induced nasal cancer with proliferating populations of cells
Cancer Research. 1996;56(5):1012-1022.

95
208.
1996

B.N. Ames; P. Boyle; J. Douli; C.L. Galli; H. Greim; Y. Hayashi; R.N. Hill; R.D. Kimbrough; D. Krewski; R. Kroes; et al.

The use of mechanistic data in the risk assessments of ten chemicals: An introduction to the chemical-specific reviews
Pharmacology and Therapeutics. 1996;71(1-2):1-5.

5
209.
1996

Earle R. Nestmann; Douglas W. Bryant; C. Jelleff Carr; Timothy T. Fennell; Jane E. Gallagher; Nancy J. Gorelick; James A. Swenberg; Gary M. Williams

Toxicological significance of DNA adducts: Summary of discussions with an expert panel
Regulatory Toxicology and Pharmacology. 1996;24(1 II):9-18.

59
210.
1995

Nova Scheller; Ramiah Sangaiah; Asoka Ranasinghe; Venkataraman Amarnath; Avram Gold; James A. Swenberg

Synthesis of [4,5,6,8-¹³C₄]guanine, a reagent for the production of internal standards of guanyl DNA adducts
Chemical Research in Toxicology. 1995;8(3):333-337.

17
211.
1995

J.A. Swenberg

Bioassay design and MTD setting: Old methods and new approaches
Regulatory Toxicology and Pharmacology. 1995;21(1):44-51.

16
212.
1995

D.K. La; P.D. Lilly; R.J. Anderegg; J.A. Swenberg

DNA adduct formation in B6C3F1 mice and Fischer-344 rats exposed to 1,2,3-trichloropropane
Carcinogenesis. 1995;16(6):1419-1424.

12
213.
1995

J.A. Swenberg; D.K. La; N.A. Scheller; K. Wu

Dose-response relationships for carcinogens
Toxicology Letters. 1995;82-83:751-756.

49
214.
1995

R.J. Preston; T.R. Fennell; A.P. Leber; R.L. Sielken Jr.; J.A. Swenberg

Reconsideration of the genetic risk assessment for ethylene oxide exposures
Environmental and Molecular Mutagenesis. 1995;26(3):189-202.

22
215.
1994

R. Rita Misra; Su-Yin Chiang; James A. Swenberg

A comparison of two ultrasensitive methods for measuring 1,N⁶-etheno-2′- deoxyadenosine and 3,N⁴-etheno-2′-deoxycytidine in cellular DNA
Carcinogenesis. 1994;15(8):1647-1652.

12
216.
1994

Yvonne P. Dragan; James R. Hully; Jun Nakamura; Marc J. Mass; James A. Swenberg; Henry C. Pitot

Biochemical events during initiation of rat hepatocarcinogenesis
Carcinogenesis. 1994;15(7):1451-1458.

40
217.
1994

S.M. Osterman-Golkar; J.P. MacNeela; M.J. Turner; V.E. Walker; J.A. Swenberg; S.J. Sumner; N. Youtsey; T.R. Fennell

Monitoring exposure to acrylonitrile using adducts with N-terminal valine in haemoglobin
Carcinogenesis. 1994;15(12):2701-2707.

33
218.
1994

B. Strauss; P. Hanawalt; J. Swenberg

Risk assessment in environmental carcinogenesis: An American Association for Cancer Research Special Conference in Cancer Research Cosponsored by the Environmental Mutagen Society
Cancer Research. 1994;54(20):5493-5496.

7
219.
1994

D.R. Dietrich; R. Candrian; D.S. Marsman; J.A. Popp; W.K. Kaufmann; J.A. Swenberg

Retrospective assessment of liver cell proliferation via PCNA: A comparison with tritiated thymidine
Cancer Letters. 1994;79(1):45-51.

12
220.
1994

E.E. McConnell; J.A. Swenberg

Review of styrene and styrene oxide long-term animal studies
Critical Reviews in Toxicology. 1994;24(SUPPL.):S49-S55.

27
221.
1993

Susan M. O'Toole; Anthony E. Pegg; James A. Swenberg

Repair of O⁶-methylguanine and O⁴-methylthymidine in F344 rat liver following treatment with 1,2-dimethylhydrazine and O⁶-benzylguanine
Cancer Research. 1993;53(17):3895-3898.

24
222.
1993

Richard J. Bull; Rory B. Conolly; David M. De Marini; Robert C. MacPhail; Edward V. Ohanian; James A. Swenberg

Incorporating biologically based models into assessments of risk from chemical contaminants
Journal / American Water Works Association. 1993;85(3):49-52.

1
223.
1993

E.E. McConnell; J.A. Swenberg

Styrene and styrene oxide: results of studies on carcinogenicity in experimental animals.
IARC scientific publications. 1993;(127):323-333.

4
224.
1993

J.A. Swenberg

α(2u)-globulin nephropathy: Review of the cellular and molecular mechanisms involved and their implications for human risk assessment
Environmental Health Perspectives. 1993;101(SUPPL. 6):39-44.

35
225.
1993

J.A. Swenberg

Cell proliferation and chemical carcinogenesis: Conference summary and future directions
Environmental Health Perspectives. 1993;101(SUPPL. 5):153-158.

24
226.
1993

S.J. Borghoff; L.D. Lehman-McKeeman; B.G. Short; G.C. Hard; J.A. Swenberg

Critique of R. Melnick's 'an alternative hypothesis on the role of chemically induced protein droplet (α2u-globulin) nephropathy in renal carcinogenesis'
Regulatory Toxicology and Pharmacology. 1993;18(2):357-364.

8
227.
1993

V.E. Walker; T.R. Fennell; P.B. Upton; J.P. MacNeela; J.A. Swenberg

Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide
Environmental Health Perspectives. 1993;99:11-17.

35
228.
1993

M.E. Hegi; P. Soderkvist; J.F. Foley; R. Schoonhoven; J.A. Swenberg; F. Kari; R. Maronpot; M.W. Anderson; R.W. Wiseman

Characterization of p53 mutations in methylene chloride-induced lung tumors from B6C3F1 mice
Carcinogenesis. 1993;14(5):803-810.

65
229.
1992

Susan J. Borghoff; Nancy L. Youtsey; James A. Swenberg

A comparison of European High Test gasoline and PS-6 unleaded gasoline in their abilities to induce α_2u-globulin nephropathy and renal cell proliferation
Toxicology Letters. 1992;63(1):21-33.

20
230.
1992

S. Maynard Bronstein; Michelle J. Hooth; James A. Swenberg; Thomas R. Skopek

Modulation of ethylnitrosourea-induced toxicity and mutagenicity in human cells by O⁶-benzylguanine
Cancer Research. 1992;52(14):3851-3856.

13
231.
1992

J.A. Swenberg; N. Fedtke; F. Ciroussel; A. Barbin; H. Bartsch

Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver
Carcinogenesis. 1992;13(4):727-729.

75
232.
1992

S.M. Bronstein; T.R. Skopek; J.A. Swenberg

Efficient repair of O⁶-ethylguanine, but not O⁴-ethylthymine or O²- ethylthymine, is dependent upon O⁶-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells
Cancer Research. 1992;52(7):2008-2011.

72
233.
1992

N.F. Cariello; J.A. Swenberg; T.R. Skopek

In vitro mutational specificity of cisplatin in the human hypoxanthine guanine phosphoribosyltransferase gene
Cancer Research. 1992;52(10):2866-2873.

22
234.
1992

V.E. Walker; J.P. MacNeela; J.A. Swenberg; M.J. Turner Jr.; T.R. Fennell

Molecular dosimetry of ethylene oxide: Formation and persistence of N-(2- hydroxyethyl)valine in hemoglobin following repeated exposures of rats and mice
Cancer Research. 1992;52(16):4320-4327.

43
235.
1992

V.E. Walker; T.R. Fennell; P.B. Upton; T.R. Skopek; V. Prevost; D.E.G. Shuker; J.A. Swenberg

Molecular dosimetry of ethylene oxide: Formation and persistence of 7-(2- hydroxyethyl)guanine in DNA following repeated exposures of rats and mice
Cancer Research. 1992;52(16):4328-4334.

73
236.
1992

V.S. Goldmacher; S.M. Bronstein; T.R. Skopek; J.A. Swenberg

Correspondence re: S. M. Bronstein et al. Efficient repair of O⁶- ethylguanine, but not O⁴-ethylthymine or O²-ethylthymine, is dependent upon O⁶-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells. Cancer Res., 52: 2008-2011, 1992
Cancer Research. 1992;52(24):6983-6985.

1
237.
1992

J.A. Swenberg; D.R. Dietrich; R.M. McClain; S.M. Cohen

Species-specific mechanisms of carcinogenesis.
IARC scientific publications. 1992;(116):477-500.

6
238.
1991

Neal F. Cariello; James A. Swenberg; Thomas R. Skopek

Fidelity of Thermococcus litoralis DNA polymerase (Vent™) in PCR determined by denaturing gradient gel electrophoresis
Nucleic Acids Research. 1991;19(15):4193-4198.

44
239.
1991

Daniel R. Dietrich; James A. Swenberg

The presence of α_2u-globulin is necessary for d-limonene promotion of male rat kidney tumors
Cancer Research. 1991;51(13):3512-3521.

81
240.
1991

D.R. Dietrich; J.A. Swenberg

NCI-Black-Reiter (NBR) male rats fail to develop renal disease following exposure to agents that induce α-2u-globulin (α_2u) nephropathy
Fundamental and Applied Toxicology. 1991;16(4):749-762.

29
241.
1991

D.R. Dietrich; J.A. Swenberg

NCI-Black-Reiter (NBR) male rats fail to develop renal disease following exposure to agents that induce α-2u-Globulin (α_2u) nephropathy
Toxicological Sciences. 1991;16(4):749-762.

1
242.
1991

Alan E. Roberts; Gregory L. Kedderis; Max J. Turner; Douglas E. Rickert; James A. Swenberg

Species comparison of acrylonitrile epoxidation by microsomes from mice, rats and humans: Relationship to epoxide concentrations in mouse and rat blood
Carcinogenesis. 1991;12(3):401-404.

23
243.
1991

Susan J. Borghoff; Aaron B. Miller; J.Phillip Bowen; James A. Swenberg

Characteristics of chemical binding to α_2u-globulin, in vitro-Evaluating structure-activity relationships
Toxicology and Applied Pharmacology. 1991;107(2):228-238.

28
244.
1991

S.M. Bronstein; J.E. Cochrane; T.R. Craft; J.A. Swenberg; T.R. Skopek

Toxicity, mutagenicity, and mutational spectra of N-ethyl-N-nitrosourea in human cell lines with different DNA repair phenotypes
Cancer Research. 1991;51(19):5188-5197.

52
245.
1991

J.A. Swenberg

Risk assessment of chemicals causing α(2u)-globulin nephropathy
Regulatory Toxicology and Pharmacology. 1991;13(1):1-2.

6
246.
1991

B.G. Short; J.A. Swenberg

Chemically induced cell proliferation in carcinogenesis in the male rat kidney.
Progress in clinical and biological research. 1991;369:357-367.

1
247.
1991

J.A. Swenberg; R.R. Maronpot

Chemically induced cell proliferation as a criterion in selecting doses for long-term bioassays.
Progress in clinical and biological research. 1991;369:245-251.

3
248.
1991

M.A. Ibrahim; G.G. Bond; T.A. Burke; P. Cole; F.N. Dost; P.E. Enterline; M. Gough; R.S. Greenberg; W.E. Halperin; E. McConnell; et al.

Weight of the evidence on the human carcinogenicity of 2,4-D
Environmental Health Perspectives. 1991;96:213-222.

40
249.
1991

J.A. Swenberg; D.G. Hoel; P.N. Magee

Mechanistic and statistical insight into the large carcinogenesis bioassays on N-nitrosodiethylamine and N-nitrosodimethylamine
Cancer Research. 1991;51(23 SUPPL.):6409-6414.

38
250.
1991

D.R. Dietrich; J.A. Swenberg

Preneoplastic lesions in rodent kidney induced spontaneously or by non-genotoxic agents: Predictive nature and comparison to lesions induced by genotoxic carcinogens
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1991;248(2):239-260.

39
251.
1991

N.F. Cariello; W.G. Thilly; J.A. Swenberg; T.R. Skopek

Deletion mutagenesis during polymerase chain reaction: Dependence on DNA polymerase
Gene. 1991;99(1):105-108.

29
252.
1991

N.F. Cariello; J.A. Swenberg; A. De Bellis; T.R. Skopek

Analysis of mutations using PCR and denaturing gradient gel electrophoresis
Environmental and Molecular Mutagenesis. 1991;18(4):249-254.

8
253.
1991

J.F. Foley; D.R. Dietrich; J.A. Swenberg; R.R. Maronpot

Detection and evaluation of proliferating cell nuclear antigen (PCNA) in rat tissue by an improved immunohistochemical procedure
Journal of Histotechnology. 1991;14(4):237-241.

49
254.
1990

N. Fedtke; J.A. Boucheron; V.E. Walker; J.A. Swenberg

Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2′-oxoethyl)guanine and N²,3-ethenoguanine in rat tissue DNA
Carcinogenesis. 1990;11(8):1287-1292.

73
255.
1990

N. Fedtke; J.A. Boucheron; M.J. Turner Jr.; J.A. Swenberg

Vinyl chloride-induced DNA adducts. I: Quantitative determination of N²3-ethenoguanine based on electrophore labeling
Carcinogenesis. 1990;11(8):1279-1285.

38
256.
1990

S.J. Borghoff; B.G. Short; J.A. Swenberg

Biochemical mechanisms and pathobiology of α_2u-globulin nephropathy
Annual Review of Pharmacology and Toxicology. 1990;30(1):349-367.

90
257.
1990

V.E. Walker; T.R. Fennell; J.A. Boucheron; N. Fedtke; F. Ciroussel; J.A. Swenberg

Macromolecular adducts of ethylene oxide: A literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation
Mutation Research. 1990;233(1-2):151-164.

33
258.
1990

D.R. Dietrich; J.A. Swenberg

Lindane induces nephropathy and renal accumulation of α2u-globulin in male but not in female Fischer 344 rats or male NBR rats
Toxicology Letters. 1990;53(1-2):179-181.

8
259.
1989

Brian G. Short; Vicki L. Burnett; James A. Swenberg

Elevated proliferation of proximal tubule cells and localization of accumulated α_2u-globulin in F344 rats during chronic exposure to unleaded gasoline or 2,2,4-trimethylpentane
Toxicology and Applied Pharmacology. 1989;101(3):414-431.

47
260.
1989

Michel Charbonneau; Josef Strasser Jr.; Edward A. Lock; Max J. Turner Jr.; James A. Swenberg

Involvement of reversible binding to α_2u-globulin in 1,4-dichlorobenzene-induced nephrotoxicity
Toxicology and Applied Pharmacology. 1989;99(1):122-132.

38
261.
1989

B.G. Short; W.H. Steinhagen; J.A. Swenberg

Promoting effects of unleaded gasoline and 2,2,4-trimethylpentane on the development of atypical cell foci and renal tubular cell tumors in rats exposed to N-ethyl-N-hydroxyethylnitrosamine
Cancer Research. 1989;49(22):6369-6378.

18
262.
1989

F.C. Richardson; J.A. Boucheron; T.R. Skopek; J.A. Swenberg

Formation of O⁶-methyldeoxyguanosine at specific sites in a synthetic oligonucleotide designed to resemble a known mutagenic hotspot
Journal of Biological Chemistry. 1989;264(2):838-841.

16
263.
1989

S.C. Schold Jr.; T.P. Brent; E. Von Hofe; H.S. Friedman; S. Mitra; D.D. Bigner; J.A. Swenberg; P. Kleihues

O⁶-Alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts
Journal of Neurosurgery. 1989;70(4):573-577.

69
264.
1989

James A. Swenberg; Brian Short; Susan Borghoff; Josef Strasser; Michel Charbonneau

The comparative pathobiology of α_2u-globulin nephropathy
Toxicology and Applied Pharmacology. 1989;97(1):35-46.

93
265.
1989

F.H. Deal; F.C. Richardson; J.A. Swenberg

Dose response of hepatocyte replication in rats following continuous exposure to diethylnitrosamine
Cancer Research. 1989;49(24 I):6985-6988.

15
266.
1989

N. Fedtke; V.E. Walker; J.A. Swenberg

Determination of 7-(2-oxoethyl)guanine and N²,3-ethenoguanine in DNA hydrolysates by HPLC
Archives of Toxicology. 1989;63(SUPPL. 13):214-218.

8
267.
1989

V.L. Burnett; B.G. Short; J.A. Swenberg

Localization of α(2u)-globulin within protein droplets of male rat kidney: Immunohistochemistry using perfusion-fixed, GMA-embedded tissue sections
Journal of Histochemistry and Cytochemistry. 1989;37(6):813-818.

21
268.
1989

M.C. Poirier; F.A. Beland; F.H. Deal; J.A. Swenberg

DNA adduct formation and removal in specific liver cell populations during chronic dietary administration of 2-acetylaminofluorene
Carcinogenesis. 1989;10(6):1143-1145.

7
269.
1989

V.E. Walker; J.A. Swenberg

Phenobarbital lacks promoting activity for neurogenic tumors in F344 rats transplacentally exposed to ethylnitrosourea
Journal of Neuropathology and Experimental Neurology. 1989;48(3):263-269.

5
270.
1988

F.C. Richardson; P.H. Morgan; J.A. Boucheron; F.H. Deal; J.A. Swenberg

Hepatocyte initiation during continuous administration of diethylnitrosamine and 1,2-sym-dimethylhydrazine
Cancer Research. 1988;48(4):988-992.

8
271.
1988

T.P. Brent; M.E. Dolan; H. Fraenkel-Conrat; J. Hall; P. Karran; F. Laval; G.P. Margison; R. Montesano; A.E. Pegg; P.M. Potter; et al.

Repair of O-alkylpyrimidines in mammalian cells: A present consensus
Proceedings of the National Academy of Sciences of the United States of America. 1988;85(6):1759-1762.

30
272.
1987

Edward A. Lock; Michel Charbonneau; Josef Strasser; James A. Swenberg; James S. Bus

2,2,4-Trimethylpentane-induced nephrotoxicity. II. The reversible binding of a TMP metabolite to a renal protein fraction containing α_2u-globulin
Toxicology and Applied Pharmacology. 1987;91(2):182-192.

28
273.
1987

Linda K. Garvey; James A. Swenberg; Thomas E. Hammn; James A. Popp

Di(2-ethythexyl)phthalate: Lack of initiating activity in the liver of female F-344 rats
Carcinogenesis. 1987;8(2):285-290.

6
274.
1987

J.A. Swenberg; J.A. Boucheron; F.H. Deal; F.C. Richardson; L.A. Tyeryar

Molecular dosimetry of DNA alkylation during chronic exposure to carcinogens.
IARC scientific publications. 1987;(84):59-63.

0
275.
1987

S.A. Belinsky; J.A. Swenberg; M.W. Anderson

Molecular dosimetry of O6-methylguanine formation and cell toxicity in lung and nasal mucosa by 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone.
IARC scientific publications. 1987;(84):430-433.

1
276.
1987

S.A. Belinsky; V.E. Walker; R.R. Maronpot; J.A. Swenberg; M.W. Anderson

Molecular dosimetry of DNA adduct formation and cell toxicity in rat nasal mucosa following exposure to the tobacco specific nitrosamine 4-(N-methyl-N-nitrosamine)-1-(3-pyridyl)-1-butanone and their relationship to induction of neoplasia
Cancer Research. 1987;47(22):6058-6065.

28
277.
1987

B.G. Short; V.L. Burnett; M.G. Cox; J.S. Bus; J.A. Swenberg

Site-specific renal cytotoxicity and cell proliferation in male rats exposed to petroleum hydrocarbons
Laboratory Investigation. 1987;57(5):564-577.

30
278.
1987

J.A. Swenberg; F.C. Richardson; J.A. Boucheron; F.H. Deal; S.A. Belinsky; M. Charbonneau; B.G. Short

High- to low-dose extrapolation: Critical determinants involved in the dose response of carcinogenic substances
Environmental Health Perspectives. 1987;76:57-63.

18
279.
1987

J.A. Swenberg; T.R. Fennell

DNA damage and repair in mouse liver
Archives of Toxicology. 1987;60(SUPPL. 10):162-171.

2
280.
1987

J.A. Swenberg; F.C. Richardson; L. Tyeryar; F. Deal; J. Boucheron

The molecular dosimetry of DNA adducts formed by continuous exposure of rats to alkylating hepatocarcinogens.
Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progres de la recherche experimentale des tumeurs. 1987;31:42-51.

2
281.
1987

S.A. Belinsky; C.M. White; T.R. Devereux; J.A. Swenberg; M.W. Anderson

Cell selective alkylation of DNA in rat lung following low dose exposure to the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
Cancer Research. 1987;47(4):1143-1148.

22
282.
1987

J.A. Boucheron; F.C. Richardson; P.H. Morgan; J.A. Swenberg

Molecular dosimetry of O⁴-ethyldeoxythymidine in rats continuously exposed to diethylnitrosamine
Cancer Research. 1987;47(6):1577-1581.

22
283.
1987

F.C. Richardson; R.O. Beauchamp Jr.; J.A. Swenberg

Properties and biological consequences of alkylpyrimidine deoxyribonucleosides
Pharmacology and Therapeutics. 1987;34(2):181-213.

1
284.
1987

K.K. Richardson; F.C. Richardson; R.M. Crosby; J.A. Swenberg; T.R. Skopek

DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea
Proceedings of the National Academy of Sciences of the United States of America. 1987;84(2):344-348.

70
285.
1986

B.G. Short; V.L. Burnett; J.A. Swenberg

Histopathology and cell proliferation induced by 2,2,4-trimethylpentane in the male rat kidney
Toxicologic Pathology. 1986;14(2):194-203.

9
286.
1986

S.A. Belinsky; C.M. White; J.A. Boucheron; F.C. Richardson; J.A. Swenberg; M. Anderson

Accumulation and persistence of DNA adducts in respiratory tissue of rats following multiple administrations of the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
Cancer Research. 1986;46(3):1280-1284.

36
287.
1986

E.E. McConnell; H.A. Solleveld; J.A. Swenberg; G.A. Boorman

Guidelines for combining neoplasms for evaluation of rodent carcinogenesis studies
Journal of the National Cancer Institute. 1986;76(2):283-289.

60
288.
1986

J.A. Swenberg

Brain tumours - problems and perspectives
Food and Chemical Toxicology. 1986;24(2):155-158.

2
289.
1986

F.C. Richardson; J.A. Boucheron; M.C. Dyroff; J.A. Popp; J.A. Swenberg

Biochemical and morphologic studies of heterogeneous lobe responses in hepatocarcinogenesis
Carcinogenesis. 1986;7(2):247-251.

17
290.
1986

M.A. Bedell; M.C. Dyroff; G. Doerjer; J.A. Swenberg

Quantitation of etheno adducts by fluorescence detection.
IARC scientific publications. 1986;(70):425-436.

3
291.
1985

L.A. Buckley; K.T. Morgan; J.A. Swenberg; R.A. James; T.E. Hamm Jr.; C.S. Barrow

The toxicity of dimethylamine in F-344 rats and B6C3F1 mice following a 1-year inhalation exposure
Fundamental and Applied Toxicology. 1985;5(2):341-352.

20
292.
1985

L.A. Buckley; K.T. Morgan; J.A. Swenberg; R.A. James; T.E. Hamm; C.S. Barrow

The toxicity of dimethylamine in F-344 rats and B6C3F1 mice following a 1-year inhalation exposure
Toxicological Sciences. 1985;5(2):341-352.

0
293.
1985

F.C. Richardson; M.C. Dyroff; J.A. Boucheron; J.A. Swenberg

Differential repair of O⁴-alkylthymidine following exposure to methylating and ethylating hepatocarcinogens
Carcinogenesis. 1985;6(4):625-629.

25
294.
1985

P.M. Silverman; J.A. Popp; J.A. Swenberg; C.E. Putman

A CT technique to evaluate the development of carcinogen-induced neoplasia in the rat liver
Investigative Radiology. 1985;20(3):267-271.

1
295.
1985

J.A. Boucheron; F.C. Richardson; J.A. Swenberg

Molecular dosimetry of O⁴-ethylthymidine (O⁴EtdT) in rats chronically exposed to diethylnitrosamine (DEN)
Proceedings of the American Association for Cancer Research. 1985;VOL. 26:No. 351.

0
296.
1985

Thomas B. Starr; James E. Gibson; Craig S. Barrow; Craig J. Boreiko; Henry d'A. Heck; Richard J. Levine; Kevin T. Morgan; James A. Swenberg

ESTIMATING HUMAN CANCER RISK FROM FORMALDEHYDE: CRITICAL ISSUES.
Advances in Chemistry Series. 1985:299-333.

1
297.
1985

J.A. Swenberg; F.C. Richardson; J.A. Boucheron; M.C. Dyroff

Relationships between DNA adduct formation and carcinogenesis
Environmental Health Perspectives. 1985;VOL. 62:177-183.

42
298.
1985

J.A. Popp; L.K. Garvey; T.E. Hamm Jr.; J.A. Swenberg

Lack of hepatic promotional activity by the peroxisomal proliferating hepatocarcinogen di(2-ethylhexyl)phthalate
Carcinogenesis. 1985;6(1):141-144.

6
299.
1984

F.L. Cavender; H.W. Casey; H. Salem; D.G. Graham; J.A. Swenberg; E.J. Gralla

A 13-week vapor inhalation study of n-hexane in rats with emphasis on neurotoxic effects
Fundamental and Applied Toxicology. 1984;4(2 PART 1):191-201.

2
300.
1984

F.L. Cavender; H.W. Casey; H. Salem; D.G. Graham; J.A. Swenberg; E.J. Gralla

A 13-week vapor inhalation study of n-hexane in rats with emphasis on neurotoxic effects
Toxicological Sciences. 1984;4(2 PART1):191-201.

0
301.
1984

T.B. Starr; J.E. Gibson; C.S. Barrow; C.J. Boreiko; H.d'A. Heck; R.J. Levine; K.T. Morgan; J.A. Swenberg

ESTIMATING HUMAN CANCER RISK FROM FORMALDEHYDE: CRITICAL ISSUES.
National Meeting - American Chemical Society, Division of Environmental Chemistry. 1984;24(1):1.

0
302.
1984

K.T. Morgan; C.H. Frith; J.A. Swenberg; J.T. McGrath; K.J. Zulch; D.M. Crowder

A morphologic classification of brain tumors found in several strains of mice
Journal of the National Cancer Institute. 1984;72(1):151-160.

14
303.
1984

J.A. Swenberg; M.C. Dyroff; M.A. Bedell

O⁴-ethyldeoxythymidine, but not O⁶-ethyldeoxyguanosine, accumulates in hepatocyte DNA of rats exposed continuously to diethylnitrosamine
Proceedings of the National Academy of Sciences of the United States of America. 1984;81(6 I):1692-1695.

28
304.
1984

D. Toorchen; C. Lindamood III; J.A. Swenberg; M.D. Topal

O⁶-methylguanine-DNA transmethylase converts O⁶-methylguanine thymine base pairs to guanine thymine base pairs in DNA
Carcinogenesis. 1984;5(12):1733-1735.

2
305.
1983

Charles Lindamood III; Mary A. Bedell; Kathryn C. Billings; Martin C. Dyroff; James A. Swenberg

O⁶-Alkylguanine alkyl acceptor protein activity in hepatocytes of C3H and C57BL mice during dimethylnitrosamine exposure
Chemico-Biological Interactions. 1983;45(3):381-385.

3
306.
1983

Finis E. Cavender; Harold W. Casey; Harry Salem; James A. Swenberg; Edward J. Gralla

A 90-day vapor inhalation toxicity study of methyl ethyl ketone
Fundamental and Applied Toxicology. 1983;3(4):264-270.

4
307.
1983

Finis L. Cavender; Harold W. Casey; Harry Salem; James A. Swenberg; Edward J. Gralla

A 90-day vapor inhalation toxicity study of methyl ethyl ketone
Toxicological Sciences. 1983;3(4):264-270.

0
308.
1983

J.G. Lewis; J.A. Swenberg

The kinetics of DNA alkylation, repair and replication in hepatocytes, Kupffer cells, and sinusoidal endothelial cells in rat liver during continuous exposure to 1,2-dimethylhydrazine
Carcinogenesis. 1983;4(5):529-536.

6
309.
1983

J.C.F. Chang; E.A. Gross; J.A. Swenberg; C.S. Barrow

Nasal cavity deposition, histopathology, and cell proliferation after single or repeated formaldehyde exposures in B6C3F1 mice and F-344 rats
Toxicology and Applied Pharmacology. 1983;68(2):161-176.

49
310.
1983

W.D. Kerns; K.L. Pavkov; D.J. Donofrio; E.J. Gralla; J.A. Swenberg

Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure
Cancer Research. 1983;43(9):4382-4392.

216
311.
1983

J.A. Swenberg; D.E. Rickert; B.L. Baranyi; J.I. Goodman

Cell specificity in DNA binding and repair of chemical carcinogens
Environmental Health Perspectives. 1983;Vol. 49:155-163.

2
312.
1983

J.A. Swenberg; M.A. Bedell; K.C. Billings; J.G. Lewis

Cell specificity in DNA damage and repair.
Basic life sciences. 1983;24:605-617.

0
313.
1983

J.A. Swenberg; C.S. Barrow; C.J. Boreiko; H.D. Heck; R.J. Levine; K.T. Morgan; T.B. Starr

Non-linear biological responses to formaldehyde and their implications for carcinogenic risk assessment
Carcinogenesis. 1983;4(8):945-952.

27
314.
1982

Kevin T. Morgan; James A. Swenberg; Thomas E. Hamm Jr.; Rochelle Wolkowski-Tyl; Mark Phelps

Histopathology of acute toxic response in rats and mice exposed to methyl chloride by inhalation
Fundamental and Applied Toxicology. 1982;2(6):293-299.

7
315.
1982

Kevin T. Morgan; James A. Swenberg; Thomas E. Hamm; Rochelle Wolkowski-tyl; Mark Phelps

Histopathology of acute toxic response in rats and mice exposed to methyl chloride by inhalation
Toxicological Sciences. 1982;2(6):293-299.

0
316.
1982

Douglas J. Kornbrust; James S. Bus; Gerhard Doerjer; J.A. Swenberg

Association of inhaled [¹⁴C]methyl chloride with macromolecules from various rat tissues
Toxicology and Applied Pharmacology. 1982;65(1):122-134.

7
317.
1982

J.G. Lewis; J.A. Swenberg

Effect of 1,2-dimethylhydrazine and diethylnitrosamine on cell replication and unscheduled DNA synthesis in target and nontarget cell populations in rat liver following chronic administration.
Cancer Research. 1982;42(1):89-92.

5
318.
1982

J.A. Swenberg

Current approaches to the experimental investigation of chemicals in relation to cancer of the brain
Annals of the New York Academy of Sciences. 1982;Vol. 381:43-49.

7
319.
1982

E.A. Gross; J.A. Swenberg; S. Fields; J.A. Popp

Comparative morphometry of the nasal cavity in rats and mice
Journal of Anatomy. 1982;135(1):83-88.

66
320.
1982

J.A. Swenberg; E.A. Gross; K.T. Morgan

Effects of formaldehyde concentration on deposition and cell proliferation
Proceedings of the American Association for Cancer Research. 1982;Vol. 23:No. 214.

0
321.
1982

M.A. Bedell; J.G. Lewis; K.C. Billings; J.A. Swenberg

Cell specificity in hepatocarcinogenesis: Preferential accumulation of O⁶-methylguanine in target cell DNA during continuous exposure of rats to 1,2-dimethylhydrazine
Cancer Research. 1982;42(8):3079-3083.

14
322.
1982

W.H. Steinhagen; J.A. Swenberg; C.S. Barrow

Acute inhalation toxicity and sensory irritation of dimethylamine
American Industrial Hygiene Association Journal. 1982;43(6):411-417.

5
323.
1982

C. Lindamood III; M.A. Bedell; J.A. Swenberg

Alkylation and de novo synthesis of liver cell DNA from C3H mice during continuous dimethylnitrosamine exposure
Cancer Research. 1982;42(10):4153-4157.

6
324.
1982

S.A. Belinsky; M.A. Bedell; J.A. Swenberg

Effect of chronic ethanol diet on the replication, alkylation, and repair of DNA from hepatocytes and nonparenchymal cells following dimethylnitrosamine administration
Carcinogenesis. 1982;3(11):1293-1297.

5
325.
1982

J.A. Swenberg; M.A. Bedell; K.C. Billings; D.R. Umbenhauer; A.E. Pegg

Cell-specific differences of O ⁶-alkylguanine DNA repair activity during continuous exposure to carcinogen
Proceedings of the National Academy of Sciences of the United States of America. 1982;79(18 I):5499-5502.

22
326.
1981

J.A. Swenberg; M.A. Bedell; K.C. Billings; J.G. Lewis

Cell specific differences in alkylation, repair and replication in hepatocarcinogenesis
Journal of Supramolecular and Cellular Biochemistry. 1981;15(Suppl.5):No. 538.

0
327.
1981

J.G. Lewis; M.A. Bedell; K.C. Billings; J.A. Swenberg

Differences in DNA alkylation, repair and replication in hepatocytes and nonparenchymal cells (NPC) following chronic administration of 1,2-dimethylhydrazine (SDMH)
Proceedings of the American Association for Cancer Research. 1981;Vol. 22:295.

0
328.
1981

P.R. Harbach; J.A. Swenberg

Effects of selenium on 1,2-dimethylhydrazine metabolism and DNA alkylation
Carcinogenesis. 1981;2(7):575-580.

2
329.
1980

J.G. Lewis; J.A. Swenberg

Differential repair of O⁶-methylguanine in DNA of rat hepatocytes and nonparenchymal cells
Nature. 1980;288(5787):185-187.

11
330.
1980

J. Swenberg; W. Kerns; K. Pavkov; R. Mitchell; E.J. Gralla

Carcinogenicity of formaldehyde vapor: interim findings in a long-term bioassay of rats and mice.
Developments in toxicology and environmental science. 1980;8:283-286.

4
331.
1980

J.A. Swenberg

In vivo methods for evaluating genotoxicity.
Developments in toxicology and environmental science. 1980;8:165-170.

0
332.
1980

J.A. Swenberg; W.D. Kerns; R.I. Mitchell; E.J. Gralla; K.L. Pavkov

Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor
Cancer Research. 1980;40(9):3398-3402.

134
333.
1980

J. Swenberg; W. Kerns; K. Pavkov

Carcinogenicity of formaldehyde vapor: Interim findings in a long-term bioassay of rats and mice
Toxicology Letters. 1980;6(SPEC.):O102.

0
334.
1979

P. Kleihues; G. Doerjer; J.A. Swenberg; E. Hauenstein; J. Bücheler; H.K. Cooper

DNA repair as regulatory factor in the organotropy of alkylating carcinogens.
Archives of toxicology. Supplement. Archiv fur Toxikologie. Supplement. 1979;(2):253-261.

3
335.
1979

J.A. Swenberg; H.K. Cooper; J. Bucheler; P. Kleihues

1,2-Dimethylhydrazine-induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram
Cancer Research. 1979;39(2 I):465-467.

33
336.
1979

P. Kleihues; G. Doerjer; J.A. Swenberg

DNA repair as regulatory factor in the organotropy of alkylating carcinogens
Archives of Toxicology. 1979;41(2 supp.):253-261.

0
337.
1979

J.P. McGovren; G.L. Neil; R.H. Denlinger; T.L. Hall; S.L. Crampton; J.A. Swenberg

Chronic cardiotoxicity studies in rabbits with 7-con-O-methylnogarol, a new anthracycline antitumor agent
Cancer Research. 1979;39(12):4849-4855.

7
338.
1979

A. Koestner; J.A. Swenberg; R.H. Denlinger

Host factors affecting perinatal carcinogenesis by resorptive alkylnitrosoureas in rats
National Cancer Institute Monograph. 1979;No. 51:211-217.

1
339.
1979

J.A. Swenberg

Incorporation of transplacental exposure into routine carcinogenicity bioassays
National Cancer Institute Monograph. 1979;No. 51:265-268.

0
340.
1979

J.A. Swenberg

Nonhormonal perinatal carcinogenesis
National Cancer Institute Monograph. 1979;No. 51:101-102.

0
341.
1978

R.H. Denlinger; A. Koestner; J.A. Swenberg

Neoplasms in purebred boxer dogs following long-term administration of N-methyl-N-nitrosourea
Cancer Research. 1978;38(6):1711-1717.

1
342.
1978

G.L. Petzold; J.A. Swenberg

Detection of DNA damage induced in vivo following exposure of rats to carcinogens
Cancer Research. 1978;38(6):1589-1594.

26
343.
1978

B.K. Bhuyan; D.M. Zimmer; G. Petzold; J.A. Swenberg

Evaluation of chemicals with bacterial mutagenicity and DNA-damage assays
Mutation Research. 1978;53(2):No. 17.

0
344.
1978

J. Swenberg; H. Cooper; J. Buechler; P. Kleihues

1,2-Dimethylhydrazine induced methylation of DNA bases in various rat organs and the effect of pretreatment with disulfiram
Proceedings of the American Association for Cancer Research. 1978;Vol. 19:No. 408.

0
345.
1978

R.J. Trzos; G.L. Petzold; M.N. Brunden; J.A. Swenberg

The evaluation of sixteen carcinogens in the rat using the micronucleus test
Mutation Research. 1978;58(1):79-86.

22
346.
1977

L.H. Li; T.D. Clark; C.H. Cowie; J.A. Swenberg; H.E. Renis; K.L. Rinehart Jr.

Effects of streptovaricins and their degradation products on infectivity of Rauscher leukemia virus
Journal of the National Cancer Institute. 1977;58(2):245-249.

1
347.
1977

J.A. Swenberg

Chemical- and virus-induced brain tumors
National Cancer Institute Monograph. 1977;No. 46:3-10.

10
348.
1977

N. Allen; N.R. Clendenon; H. Abe; J.A. Swenberg; A. Koestner; W. Wechsler; E.C. Shuttleworth Jr.

Acid hydrolase and cytochrome oxidase activities in nitrosourea induced tumors of the nervous system
Acta Neuropathologica. 1977;39(1):13-23.

1
349.
1976

J.A. Swenberg

Chemical induction of brain tumors.
Advances in neurology. 1976;15:85-99.

1
350.
1976

J.A. Swenberg; G.L. Petzold; P.R. Harbach

In vitro DNA damage/alkaline elution assay for predicting carcinogenic potential
Biochemical and Biophysical Research Communications. 1976;72(2):732-738.

17
351.
1976

A. Koestner; R. Denlinger; J.A. Swenberg

Carcinogenicity of methylnitrosourea (MNU) in Boxer dogs
Proceedings of the American Association for Cancer Research. 1976;vol.17:no.325.

0
352.
1975

J.A. Swenberg; A. Koestner; W. Wechsler; M.N. Brunden; H. Abe

Differential oncogenic effects of methylnitrosourea
Journal of the National Cancer Institute. 1975;54(1):89-94.

6
353.
1975

J.A. Swenberg; N. Clendenon; R. Denlinger; W.A. Gordon

Sequential development of ethyinitrosourea induced neurinomas: morphology, biochemistry, and transplantability
Journal of the National Cancer Institute. 1975;55(1):147-151.

3
354.
1975

J.A. Swenberg; B.K. Bhuyan

Carcinogenicity evaluations of new drugs: rationale and an integrated approach
Proceedings of the American Association for Cancer Research. 1975;16(66):No. s-7.

0
355.
1974

C.D. Newton; G.P. Wilson; H.L. Allen; J.A. Swenberg

Surgical closure of elbow hygroma in the dog
J.AMER.VET.MED.ASS. 1974;164(2):147-149.

3
356.
1974

R.M. Folk; A.C. Peters; K.L. Pavkov; J.A. Swenberg

Preclinical toxicologic evaluation of 2,5 piperazinedione, 3,6 bis (5 chloro 2 piperidyl), dihydrochloride (NSC 135758) in dogs and monkeys
CANCER CHEMOTHER.REP. 1974;5(1):37-41.

0
357.
1974

N.R. Clendenon; J.A. Swenberg; N. Allen

The course of hydrolase elevation during induction of trigeminal nerve neurinomas
TRANS.AMER.SOC.NEUROCHEM. 1974;5(1):127.

0
358.
1974

H. Abe; N. Allen; N.R. Clendenon; J.A. Swenberg

Lysosomal enzymes in nitrosamine induced nervous system tumors of rats (Japanese)
Neurological Surgery. 1974;2(9):629-636.

0
359.
1974

J.A. Swenberg; D. Bigner; T.L. Hall

Experimental chemotherapy of viral induced brain tumors
Proceedings of the American Association for Cancer Research. 1974;Vol. 15:No. 170.

1
360.
1974

R.M. Folk; A.C. Peters; K.L. Pavkov; J.A. Swenberg

Vincristine (NSC 67574): A retrospective toxicologic evaluation in monkeys and dogs using weekly intravenous injections for 6 weeks
CANCER CHEMOTHER.REP. 1974;5(1):17-23.

3
361.
1973

Robert H. Denlinger; Adalbert Koestner; James A. Swenberg

An experimental model for selective production of neoplasms of the peripheral nervous system
Acta Neuropathologica. 1973;23(3):219-228.

1
362.
1973

R.H. Denlinger; J.A. Swenberg; A. Koestner; W. Wechsler

Differential effect of immunosuppression on the induction of nervous system and bladder tumors by N-methyl N-nitrosourea.
Journal of the National Cancer Institute. 1973;50(1):87-93.

1
363.
1973

W. Wechsler; S.E. Pfeiffer; J.A. Swenberg; A. Koestner

S 100 protein in methyl and ethylnitrosourea induced tumors of the rat nervous system
Acta Neuropathologica. 1973;24(4):287-303.

0
364.
1973

H.H. Traurig; N.R. Clendenon; J.A. Swenberg; N. Allen

Lysosomal acid hydrolases in neonatal rat brain
Journal of Neurobiology. 1973;4(2):105-115.

1
365.
1972

J.A. Swenberg; A. Koestner; W. Wechsler; R.H. Denlinger

Quantitative aspects of transplacental tumor induction with ethylnitrosourea in rats.
Cancer Research. 1972;32(12):2656-2660.

15
366.
1972

H.H. Traurig; N.R. Clendenon; J.A. Swenberg; N. Allen

Lysosomal acid hydrolases in primary monolayer cultures derived from neonatal brains exposed transplacentally to ethylnitrosourea.
Proceedings of the Society for Experimental Biology and Medicine. 1972;141(2):613-617.

0
367.
1972

W. Wechsler; S.E. Pfeiffer; J.A. Swenberg; A. Koestner

S 100 protein in experimental rat tumors of the central and peripheral nervous system
Die Naturwissenschaften. 1972;59(8):370-371.

0
368.
1972

J.A. Swenberg; A. Koestner; W. Wechsler

The induction of tumors of the nervous system with intravenous methylnitrosourea.
Laboratory Investigation. 1972;26(1):74-85.

14
369.
1972

A. Koestner; J.A. Swenberg; W. Wechsler

Experimental tumors of the nervous system induced by resorptive N-nitrosourea compounds.
Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progres de la recherche experimentale des tumeurs. 1972;17:9-30.

3
370.
1972

J.A. Swenberg; A. Koestner

Histochemical studies on selected enzymes of experimental neuroectodermal tumors.
Progress in experimental tumor research. Fortschritte der experimentellen Tumorforschung. Progres de la recherche experimentale des tumeurs. 1972;17:328-345.

0
371.
1971

A. Schwartz; G.P. Wilson; R.L. Hamlin; J. Swenberg; P. Termin; N.R. Thomford; E. Donovan

Constrictive pericarditis in two dogs.
Journal of the American Veterinary Medical Association. 1971;159(6):763-776.

3
372.
1971

A. Koestner; J.A. Swenberg; W. Wechsler

Transplacental production with ethylnitrosourea of neoplasms of the nervous system in Sprague-Dawley rats.
American Journal of Pathology. 1971;63(1):37-56.

73
373.
1971

J.A. Swenberg; A. Koestner; W. Wechsler

The induction of tumors of the nervous system in rats with intravenous methylnitrosourea (MNU).
Journal of Neuropathology and Experimental Neurology. 1971;30(1):122.

4
374.
1969

J.A. Swenberg; A. Koestner; R.P. Tewari

The pathogenesis of experimental mycotic encephalitis. An ultrastructural study.
Laboratory Investigation. 1969;21(5):365-373.

0
375.
1969

James A. Swenberg; Adalbert Koestner; Ram P. Tewari

Experimental mycotic encephalitis
Acta Neuropathologica. 1969;13(1):75-90.

0

James A Swenberg UNCCH, Gillings School of Global Public Health, Environmental Sciences and Engineering

James A Swenberg

James A Swenberg
UNCCH, Gillings School of Global Public Health, Environmental Sciences and Engineering