John E Sondek

UNCCH, School of Medicine, Pharmacology

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John E Sondek

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Pharmacology
  
  

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Weigang Huang; Matthew Barrett; Nicole Hajicek; Stephanie Hicks; T. Kendall Harden; John Sondek; Qisheng Zhang

  Small molecule inhibitors of phospholipase C from a novel high-throughput screen

  Journal of Biological Chemistry. 2013;288(8):5840-5848.
  0

• 2.

  2012

  Xiaoyang Wang; Matthew Barrett; John Sondek; T. Kendall Harden; Qisheng Zhang

  Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C

  Biochemistry. 2012;51(26):5300-5306.
  0

• 3.

  2012

  Karen A. Cherkis; Brenda R. S. Temple; Eui-Hwan Chung; John Sondek; Jeffery L. Dangl

  AvrRpm1 missense mutations weakly activate RPS2-mediated immune response in Arabidopsis thaliana

  PLoS ONE. 2012;7(8).
  0

• 4.

  2012

  Pablo Fernandez-Piñar; Ainel Alemán; John Sondek; Henrik G. Dohlman; María Molina; Humberto Martín

  The Salmonella typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae

  Molecular Biology of the Cell. 2012;23(22):4430-4443.
  0

• 5.

  2011

  Ryan R. Klein; David M. Bourdon; Chester L. Costales; Craig D. Wagner; Wendy L. White; Jon D. Williams; Stephanie N. Hicks; John Sondek; Dhiren R. Thakker

  Direct activation of human phospholipase C by its well known inhibitor U73122

  Journal of Biological Chemistry. 2011;286(14):12407-12416.
  11

• 6.

  2011

  Brant Hamel; Elizabeth Monaghan-Benson; Rafael J. Rojas; Brenda R. S. Temple; Daniel J. Marston; Keith Burridge; John Sondek

  SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC

  Journal of Biological Chemistry. 2011;286(14):12141-12148.
  3

• 7.

  2011

  Weigang Huang; Stephanie N. Hicks; John Sondek; Qisheng Zhang

  A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes

  ACS Chemical Biology. 2011;6(3):223-228.
  5

• 8.

  2011

  Wei Sun; Janeen L. Vanhooke; John Sondek; Qisheng Zhang

  High-throughput fluorescence polarization assay for the enzymatic activity of gtpase-activating protein of ADP-ribosylation factor (ARFGAP)

  Journal of Biomolecular Screening. 2011;16(7):717-723.
  0

• 9.

  2011

  T. Kendall Harden; Gary L. Waldo; Stephanie N. Hicks; John Sondek

  Mechanism of activation and inactivation of Gq/phospholipase C-Β signaling nodes

  Chemical Reviews. 2011;111(10):6120-6129.
  2

• 10.

  2011

  Wenwen Tang; Yong Zhang; Wenwen Xu; T. Kendall Harden; John Sondek; Le Sun; Lin Li; Dianqing Wu

  A PLCβ/PI3Kγ-GSK3 Signaling Pathway Regulates Cofilin Phosphatase Slingshot2 and Neutrophil Polarization and Chemotaxis

  Developmental Cell. 2011;21(6):1038-1050.
  5

• 11.

  2010

  Aurelie Gresset; Stephanie N. Hicks; T. Kendall Harden; John Sondek

  Mechanism of phosphorylation-induced activation of phospholipase C-γ isozymes

  Journal of Biological Chemistry. 2010;285(46):35836-35847.
  17

• 12.

  2010

  Gary L. Waldo; Tiffany K. Ricks; Stephanie N. Hicks; Matthew L. Cheever; Takeharu Kawano; Kazuhito Tsuboi; Xiaoyue Wang; Craig Montell; Tohru Kozasa; John Sondek; et al.

  Kinetic scaffolding mediated by a phospholipase C-β and G_q signaling complex

  Science. 2010;330(6006):974-980.
  38

• 13.

  2009

  Chris R. Evelyn; Timothy Ferng; Rafael J. Rojas; Martha J. Larsen; John Sondek; Richard R. Neubig

  High-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assay

  Journal of Biomolecular Screening. 2009;14(2):161-172.
  9

• 14.

  2009

  T. Kendall Harden; Stephanie N. Hicks; John Sondek

  Phospholipase C isozymes as effectors of Ras superfamily GTPases

  Journal of Lipid Research. 2009;50(SUPPL.):S243-S248.
  13

• 15.

  2009

  Erin J. Heenan; Janeen L. Vanhooke; Brenda R. Temple; Laurie Betts; John E. Sondek; Henrik G. Dohlman

  Structure and Function of Vps15 in the Endosomal G Protein Signaling Pathway

  Biochemistry. 2009;48(27):6390-6401.
  5

• 16.

  2009

  Erin J. Friedman; Brenda R.S. Temple; Stephanie N. Hicks; John Sondek; Corbin D. Jones; Alan M. Jones

  Prediction of Protein-Protein Interfaces on G-Protein β Subunits Reveals a Novel Phospholipase C β2 Binding Domain

  Journal of Molecular Biology. 2009;392(4):1044-1054.
  7

• 17.

  2008

  Matthew L. Cheever; Jason T. Snyder; Svetlana Gershburg; David P. Siderovski; T. Kendall Harden; John Sondek

  Crystal structure of the multifunctional Gβ5-RGS9 complex

  Nature Structural and Molecular Biology. 2008;15(2):155-162.
  45

• 18.

  2008

  Yixing Zhou; John Sondek; T. Kendall Harden

  Activation of human phospholipase C-η2 by Gβγ

  Biochemistry. 2008;47(15):4410-4417.
  18

• 19.

  2008

  Marielle E. Yohe; Kent Rossman; John Sondek

  Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins

  Biochemistry. 2008;47(26):6827-6839.
  12

• 20.

  2008

  Najl V. Valeyev; A. Kristina Downing; John Sondek; Charlotte Deane

  Electrostatic and functional analysis of the seven-bladed WD β-propellers

  Evolutionary Bioinformatics. 2008;2008(4):203-216.
  2

• 21.

  2008

  Stephanie N. Hicks; Mark R. Jezyk; Svetlana Gershburg; Jason P. Seifert; T. Kendall Harden; John Sondek

  General and Versatile Autoinhibition of PLC Isozymes

  Molecular Cell. 2008;31(3):383-394.
  47

• 22.

  2008

  Jason P. Seifert; Yixing Zhou; Stephanie N. Hicks; John Sondek; T. Kendall Harden

  Dual activation of phospholipase C-ε by rho and ras GTPases

  Journal of Biological Chemistry. 2008;283(44):29690-29698.
  11

• 23.

  2007

  Sompop Bencharit; Cai Bin Cui; Adnan Siddiqui; Escher L. Howard-Williams; John Sondek; Kheir Zuobi-Hasona; Ikramuddin Aukhil

  Structural Insights into Fibronectin Type III Domain-mediated Signaling

  Journal of Molecular Biology. 2007;367(2):303-309.
  14

• 24.

  2007

  Darrell Desveaux; Alex U. Singer; Ai-Jiuan Wu; Brian C. McNulty; Laura Musselwhite; Zachary Nimchuk; John Sondek; Jeffery L. Dangl

  Type III effector activation via nucleotide binding, phosphorylation, and host target interaction

  PLoS Pathogens. 2007;3(3).
  28

• 25.

  2007

  Mariya K. Chhatriwala; Laurie Betts; David K. Worthylake; John Sondek

  The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation

  Journal of Molecular Biology. 2007;368(5):1307-1320.
  21

• 26.

  2007

  Marielle E. Yohe; Kent L. Rossman; Olivia S. Gardner; Antoine E. Karnoub; Jason T. Snyder; Svetlana Gershburg; Lee M. Graves; Channing J. Der; John Sondek

  Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif

  Journal of Biological Chemistry. 2007;282(18):13813-13823.
  16

• 27.

  2007

  Darrell Desveaux; Alex U. Singer; Ai-Jiuan Wu; Brian C. McNulty; Laura Musslewhite; Zachary Nimchuk; John Sondek; Jeffrey L. Dangl

  Erratum: Type III effector activation via nucleotide binding, phosphorylation, and host target interaction (PLoS Pathogens 3, 3, DOI:10.1371/journal.ppat.0030048)

  PLoS Pathogens. 2007;3(6):0858.
  0

• 28.

  2007

  Natalia Mitin; Laurie Betts; Marielle E. Yohe; Channing J. Der; John Sondek; Kent L. Rossman

  Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression

  Nature Structural and Molecular Biology. 2007;14(9):814-823.
  24

• 29.

  2007

  Rafael J. Rojas; Marielle E. Yohe; Svetlana Gershburg; Takeharu Kawano; Tohru Kozasa; John Sondek

  Gα_q directly activates p63RhoGEF and trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain

  Journal of Biological Chemistry. 2007;282(40):29201-29210.
  49

• 30.

  2006

  Jason T. Snyder; Mark R. Jezyk; Svetlana Gershburg; T. Kendall Harden; John Sondek

  Regulation of PLCβ isoforms by Rac

  Methods in Enzymology. 2006;406:272-280.
  2

• 31.

  2006

  Jason P. Seifert; Jason T. Snyder; John Sondek; T. Kendall Harden

  Direct activation of purified phospholipase C epsilon by RhoA studied in reconstituted phospholipid vesicles

  Methods in Enzymology. 2006;406:260-271.
  2

• 32.

  2006

  David M. Bourdon; Michele R. Wing; Earl B. Edwards; John Sondek; T. Kendall Harden

  Quantification of isozyme-specific activation of phospholipase C-β2 by Rac GTPases and phospholipase C-ε by Rho GTPases in an intact cell assay system

  Methods in Enzymology. 2006;406:489-499.
  14

• 33.

  2006

  T. Kendall Harden; John Sondek

  Regulation of phospholipase C isozymes by Ras superfamily GTPases

  Annual Review of Pharmacology and Toxicology. 2006;46:355-379.
  58

• 34.

  2006

  Mark R. Jezyk; Jason T. Snyder; Svetlana Gershberg; David K. Worthylake; T. Kendall Harden; John Sondek

  Crystal structure of Rac1 bound to its effector phospholipase C-β2

  Nature Structural and Molecular Biology. 2006;13(12):1135-1140.
  51

• 35.

  2006

  Mark A. Baumeister; Kent L. Rossman; John Sondek; Mark A. Lemmon

  The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity

  Biochemical Journal. 2006;400(3):563-572.
  18

• 36.

  2005

  Kent L. Rossman; Channing J. Der; John Sondek

  GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors

  Nature Reviews Molecular Cell Biology. 2005;6(2):167-180.
  610

• 37.

  2005

  Mingjian Lu; Jason M. Kinchen; Kent L. Rossman; Cynthia Grimsley; Matthew Hall; John Sondek; Michael O. Hengartner; Vijay Yajnik; Kodi S. Ravichandran

  A steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

  Current Biology. 2005;15(4):371-377.
  44

• 38.

  2005

  Holly R. Gentry; Alex U. Singer; Laurie Betts; Cheng Yang; Joseph D. Ferrara; John Sondek; Leslie V. Parise

  Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins

  Journal of Biological Chemistry. 2005;280(9):8407-8415.
  43

• 39.

  2005

  Kent L. Rossman; John Sondek

  Larger than Dbl: New structural insights into RhoA activation

  Trends in Biochemical Sciences. 2005;30(4):163-165.
  25

• 40.

  2005

  Han-Suk Kim; Darrell Desveaux; Alex U. Singer; Priyesh Patel; John Sondek; Jeffery L. Dangl

  The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation

  Proceedings of the National Academy of Sciences of the United States of America. 2005;102(18):6496-6501.
  105

• 41.

  2005

  Christopher A. Johnston; Francis S. Willard; Mark R. Jezyk; Zoey Fredericks; Erik T. Bodor; Miller B. Jones; Rainer Blaesius; Val J. Watts; T. Kendall Harden; John Sondek; et al.

  Structure of Gα_i1 bound to a GDP-selective peptide provides insight into guanine nucleotide exchange

  Structure. 2005;13(7):1069-1080.
  34

• 42.

  2005

  William J. Smith; Brant Hamel; Marielle E. Yohe; John Sondek; Richard A. Cerione; Jason T. Snyder

  A Cdc42 mutant specifically activated by intersectin

  Biochemistry. 2005;44(40):13282-13290.
  4

• 43.

  2005

  Yixing Zhou; Michele R. Wing; John Sondek; T. Kendall Harden

  Molecular cloning and characterization of PLC-η2

  Biochemical Journal. 2005;391(3):667-676.
  27

• 44.

  2004

  Yi Chen; Sebastien Vallee; Joann Wu; Don Vu; John Sondek; Gourisankar Ghosh

  Inhibition of NF-κB Activity by IκBβ in Association with κB-Ras

  Molecular and Cellular Biology. 2004;24(7):3048-3056.
  23

• 45.

  2004

  Colin D. DeBakker; Lisa B. Haney; Jason M. Kinchen; Cynthia Grimsley; Mingjian Lu; Doris Klingele; Pei-Ken Hsu; Bin-Kuan Chou; Li-Chun Cheng; Anne Blangy; et al.

  Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO

  Current Biology. 2004;14(24):2208-2216.
  107

• 46.

  2004

  Michelle E Kimple; John Sondek

  Overview of affinity tags for protein purification.

  Current protocols in protein science / editorial board, John E. Coligan ... [et al.]. 2004;Chapter 9:Unit 9.9.
  0

• 47.

  2004

  Patricia A. Solski; Rhonda S. Wilder; Kent L. Rossman; John Sondek; Adrienne D. Cox; Sharon L. Campbell; Channing J. Der

  Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation

  Journal of Biological Chemistry. 2004;279(24):25226-25233.
  23

• 48.

  2004

  David K. Worthylake; Kent L. Rossman; John Sondek

  Crystal structure of the DH/PH fragment of Dbs without bound GTPase

  Structure. 2004;12(6):1079-1086.
  19

• 49.

  2004

  Mingjian Lu; Jason M. Kinchen; Kent L. Rossman; Cynthia Grimsley; Colin DeBakker; Enrico Brugnera; Annie-Carole Tosello-Trampont; Lisa B. Haney; Doris Klingele; John Sondek; et al.

  PH domain of ELMO functions in trans to regulate Rac activation via Dock180

  Nature Structural and Molecular Biology. 2004;11(8):756-762.
  61

• 50.

  2004

  Alex U. Singer; Darrell Desveaux; Laurie Betts; Jeff H. Chang; Zachary Nimchuk; Sarah R. Grant; Jeffery L. Dangl; John Sondek

  Crystal structures of the type III effector protein AvrPphF and its chaperone reveal residues required for plant pathogenesis

  Structure. 2004;12(9):1669-1681.
  38

• 51.

  2004

  Jason P. Seifert; Michele R. Wing; Jason T. Snyder; Svetlana Gershburg; John Sondek; T. Kendall Harden

  RhoA activates purified phospholipase C-ε by a guanine nucleotide-dependent mechanism

  Journal of Biological Chemistry. 2004;279(46):47992-47997.
  31

• 52.

  2004

  Anurag Singh; Antoine E. Karnoub; Todd R. Palmby; Ernst Lengyel; John Sondek; Channing J. Der

  Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

  Oncogene. 2004;23(58):9369-9380.
  64

• 53.

  2003

  Wendy M. Pruitt; Antoine E. Karnoub; A. Corinne Rakauskas; Michel Guipponi; Stylianos E. Antonarakis; Alexei Kurakin; Brian K. Kay; John Sondek; David P. Siderovski; et al.

  Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling

  Biochimica et Biophysica Acta - Molecular Cell Research. 2003;1640(1):61-68.
  15

• 54.

  2003

  Mark A. Baumeister; Lenka Martinu; Kent L. Rossman; John Sondek; Mark A. Lemmon; Margaret M. Chou

  Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

  Journal of Biological Chemistry. 2003;278(13):11457-11464.
  37

• 55.

  2003

  Kent L. Rossman; Li Cheng; Gwendolyn M. Mahon; Rafael J. Rojas; Jason T. Snyder; Ian P. Whitehead; John Sondek

  Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation

  Journal of Biological Chemistry. 2003;278(20):18393-18400.
  56

• 56.

  2003

  Rafael J. Rojas; Randall J. Kimple; Kent L. Rossman; David P. Siderovskil; John Sondek

  Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases

  Combinatorial Chemistry and High Throughput Screening. 2003;6(4):409-418.
  20

• 57.

  2003

  Jason T. Snyder; Alex U. Singer; Michele R. Wing; T. Kendall Harden; John Sondek

  The pleckstrin homology domain of phospholipase C-β₂ as an effector site for Rac

  Journal of Biological Chemistry. 2003;278(23):21099-21104.
  60

• 58.

  2003

  Michele R. Wing; Jason T. Snyder; John Sondek; T. Kendall Harden

  Direct Activation of Phospholipase C-ε by Rho

  Journal of Biological Chemistry. 2003;278(42):41253-41258.
  50

• 59.

  2003

  Marco A Salazar; Adam V Kwiatkowski; Lorenzo Pellegrini; Gianluca Cestra; Margaret H Butler; Kent L Rossman; Daniel M Serna; John Sondek; Frank B Gertler; et al.

  Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.

  The Journal of biological chemistry. 2003;278(49):49031-49043.
  72

• 60.

  2002

  John M. Lambert; Que T. Lambert; Gary W. Reuther; Angeliki Malliri; David P. Siderovski; John Sondek; John G. Collard; Chaning J. Der

  Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

  Nature Cell Biology. 2002;4(8):621-625.
  146

• 61.

  2002

  A.U. Singer; G.L. Waldo; T.K. Harden; J. Sondek

  A unique fold of phospholipase C-β mediates dimerization and interaction with Gαq

  Nature Structural Biology. 2002;9(1):32-36.
  57

• 62.

  2002

  Jason T. Snyder; David K. Worthylakel; Kent L. Rossman; Laurie Betts; Wendy M. Pruitt; David P. Siderovski; Channing J. Der; John Sondek

  Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

  Nature Structural Biology. 2002;9(6):468-475.
  125

• 63.

  2002

  Li Cheng; Kent L. Rossman; Gwendolyn M. Mahon; David K. Worthylake; Malgorzata Korus; John Sondek; Ian P. Whitehead

  RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity

  Molecular and Cellular Biology. 2002;22(19):6895-6905.
  24

• 64.

  2002

  William T Barry; Christel Boudignon-Proudhon; David D Shock; Andrew McFadden; Jonathan M Weiss; John Sondek; Leslie V Parise

  Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain.

  Journal of Biological Chemistry. 2002;277(32):28877-28883.
  41

• 65.

  2002

  Kent L. Rossman; David K. Worthylake; Jason T. Snyder; David P. Siderovski; Sharon L. Campbell; John Sondek

  A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange

  EMBO Journal. 2002;21(6):1315-1326.
  138

• 66.

  2002

  Randall J. Kimple; Michelle E. Kimple; Laurie Betts; John Sondek; David P. Siderovski

  Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits

  Nature. 2002;416(6883):878-881.
  141

• 67.

  2002

  Kent L. Rossman; David K. Worthylake; Jason T. Snyder; Li Cheng; Ian P. Whitehead; John Sondek

  Functional analysis of Cdc42 residues required for guanine nucleotide exchange

  Journal of Biological Chemistry. 2002;277(52):50893-50898.
  21

• 68.

  2002

  Michelle E. Kimple; John Sondek

  Affinity tag for protein purification and detection based on the disulfide-linked complex of InaD and NorpA

  BioTechniques. 2002;33(3):578-590.
  5

• 69.

  2001

  Antoine E. Karnoub; David K. Worthylake; Kent L. Rossman; Wendy Morse Pruitt; Sharon L. Campbell; John Sondek; Channing J. Der

  Molecular basis for Rac1 recognition by guanine nucleotide exchange factors

  Nature Structural Biology. 2001;8(12):1037-1041.
  64

• 70.

  2001

  John Sondek; David P. Siderovski

  Gγ-like (GGL) domains: New frontiers in G-protein signaling and β-propeller scaffolding

  Biochemical Pharmacology. 2001;61(11):1329-1337.
  82

• 71.

  2001

  David P. Siderovski; Bryan E. Snow; Stephen Chung; Greg M. Brothers; John Sondek; Laurie Betts

  Assays of complex formation between RGS protein Gγ subunit-like domains and Gβ subunits

  Methods in Enzymology. 2001;344:702-723.
  3

• 72.

  2001

  Jason T. Snyder; Kent L. Rossman; Mark A. Baumeister; Wendy M. Pruitt; David P. Siderovski; Channing J. Der; Mark A. Lemmon; John Sondek

  Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

  Journal of Biological Chemistry. 2001;276(49):45868-45875.
  58

• 73.

  2001

  Michelle E. Kimple; David P. Siderovski; John Sondek

  Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA

  EMBO Journal. 2001;20(16):4414-4422.
  29

• 74.

  2001

  Gary W. Reuther; Que T. Lambert; Michelle A. Booden; Krister Wennerberg; Brian Becknell; Guido Marcucci; John Sondek; Michael A. Caligiuri; Channing J. Der

  Leukemia-associated Rho Guanine Nucleotide Exchange Factor, a Dbl Family Protein Found Mutated in Leukemia, Causes Transformation by Activation of RhoA

  Journal of Biological Chemistry. 2001;276(29):27145-27151.
  75

• 75.

  2000

  David K. Worthylake; Kent L. Rossman; John Sondek

  Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

  Nature. 2000;408(6813):682-688.
  217

• 76.

  1999

  Bryan E. Snow; Laurie Betts; Joan Mangion; John Sondek; David P. Siderovski

  Fidelity of G protein β-subunit association by the G protein γ-subunit-like domains of RGS6, RGS7, and RGS11

  Proceedings of the National Academy of Sciences of the United States of America. 1999;96(11):6489-6494.
  84

• 77.

  1999

  David D. Shock; Ulhas P. Naik; Julia E. Brittain; Suresh K. Alahari; John Sondek; Leslie V. Parise

  Calcium-dependent properties of CIB binding to the integrin αIIb cytoplasmic domain and translocation to the platelet cytoskeleton

  Biochemical Journal. 1999;342(3):729-735.
  44

• 78.

  1997

  N. Skiba; H. Bae; C. Ford; Y. Daaka; E. Reuvenv; L. Shekter; T. Van Biesen; C.-S. Yang; D. Lambright; J. Sondek; et al.

  Molecular basis for gβγ-effector interaction: Structural correlation with ga binding site

  FASEB Journal. 1997;11(9):A1340.
  0

• 79.

  1996

  David G. Lambright; John Sondek; Andrew Bohm; Nikolai P. Skiba; Heidi E. Hamm; Paul B. Sigler

  The 2.0 Å crystal structure of a heterotrimeric G protein

  Nature. 1996;379(6563):311-319.
  841

• 80.

  1996

  John Sondek; Andrew Bohm; David G. Lambright; Heidi E. Hamm; Paul B. Sigier

  Crystal structure of a G_A protein βγ dimer at 2.1Å resolution

  Nature. 1996;379(6563):369-374.
  600

• 81.

  1996

  J. Sondek; A. Bohm; D.G. Lambright; H.E. Hamm; P.B. Sigler

  Erratum: Crystal structure of a G-protein βγ dimer at 2.1Å resolution (Nature (1996) 379 (369-374))

  Nature. 1996;379(6568):847.
  3

• 82.

  1995

  V.Z. Slepak; N.O. Artemyev; Y. Zhu; C.L. Dumke; L. Sabacan; J. Sondek; H.E. Hamm; M.D. Bownds; V.Y. Arshavsky

  An effector site that stimulates G-protein GTPase in photoreceptors

  Journal of Biological Chemistry. 1995;270(24):14319-14324.
  48

• 83.

  1994

  John Sondek; David G. Lambright; Joseph P. Noel; Heidi E. Hamm; Paul B. Sigler

  GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α · GDP · AlF₄^-

  Nature. 1994;372(6503):276-279.
  416

• 84.

  1994

  L.J. Keefe; S. Quirk; A. Gittis; J. Sondek; E.E. Lattman

  Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease

  Protein Science. 1994;3(3):391-401.
  16

• 85.

  1993

  L.J. Keefe; J. Sondek; D. Shortle; E.E. Lattman

  The α aneurism: A structural motif revealed in an insertion mutant of staphylococcal nuclease

  Proceedings of the National Academy of Sciences of the United States of America. 1993;90(8):3275-3279.
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• 86.

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  A general strategy for random insertion and substitution mutagenesis: Substoichiometric coupling of trinucleotide phosphoramidites

  Proceedings of the National Academy of Sciences of the United States of America. 1992;89(8):3581-3585.
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  1992

  P.J. Thomas; P. Shenbagamurthi; J. Sondek; J.M. Hullihen; P.L. Pedersen

  The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide

  Journal of Biological Chemistry. 1992;267(9):5727-5730.
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  1992

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  Structural and energetic differences between insertions and substitutions in staphylococcal nuclease

  Proteins: Structure, Function and Genetics. 1992;13(2):132-140.
  16

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  1990

  J. Sondek; D. Shortle

  Accomodation of single amino acid insertions by the native state of staphylococcal nuclease

  Proteins: Structure, Function and Genetics. 1990;7(4):299-305.
  32