Kenneth F Bastow

UNCCH, Eshelman School of Pharmacy, Pharmacy

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Kenneth F Bastow

• Organizations
  University of North Carolina at Chapel Hill
  
  Eshelman School of Pharmacy
  
  Pharmacy
  
  

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Qi Wang; Tzu-Hsuan Chen; Kenneth F. Bastow; Susan L. Morris-Natschke; Kuo-Hsiung Lee; Dao-Feng Chen

  Songaricalarins A-E, cytotoxic oplopane sesquiterpenes from Ligularia songarica

  Journal of Natural Products. 2013;76(3):305-310.
  0

• 2.

  2013

  Xiao-Feng Wang; Emika Ohkoshi; Sheng-Biao Wang; Ernest Hamel; Kenneth F. Bastow; Susan L. Morris-Natschke; Kuo-Hsiung Lee; Lan Xie

  Synthesis and biological evaluation of N-alkyl-N-(4-methoxyphenyl)pyridin- 2-amines as a new class of tubulin polymerization inhibitors

  Bioorganic and Medicinal Chemistry. 2013;21(3):632-642.
  0

• 3.

  2012

  Xiao-Feng Wang; Xing-Tao Tian; Emika Ohkoshi; Bingjie Qin; Yi-Nan Liu; Pei-Chi Wu; Mann-Jen Hour; Hsin-Yi Hung; Keduo Qian; Rong Huang; et al.

  Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents

  Bioorganic and Medicinal Chemistry Letters. 2012;22(19):6224-6228.
  1

• 4.

  2012

  Xiaoming Yang; Qian Shi; Chin-Yu Lai; Chi-Yuan Chen; Emika Ohkoshi; Shuenn-Chen Yang; Chih-Ya Wang; Kenneth F. Bastow; Tian-Shung Wu; Shiow-Lin Pan; et al.

  Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: Design, synthesis, and mechanistic studies

  Journal of Medicinal Chemistry. 2012;55(15):6751-6761.
  2

• 5.

  2012

  Chiao-Ting Yen; Kyoko Nakagawa-Goto; Tsong-Long Hwang; Susan L. Morris-Natschke; Kenneth F. Bastow; Yang-Chang Wu; Kuo-Hsiung Lee

  Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents

  Bioorganic and Medicinal Chemistry Letters. 2012;22(12):4018-4022.
  0

• 6.

  2012

  Hsin-Yi Hung; Emika Ohkoshi; Masuo Goto; Kenneth F. Bastow; Kyoko Nakagawa-Goto; Kuo-Hsiung Lee

  Antitumor agents. 293. Nontoxic dimethyl-4,4′-dimethoxy-5,6,5′, 6′-dimethylenedioxybiphenyl-2,2′-dicarboxylate (DDB) analogues chemosensitize multidrug-resistant cancer cells to clinical anticancer drugs

  Journal of Medicinal Chemistry. 2012;55(11):5413-5424.
  2

• 7.

  2012

  Ting Zhou; Emika Ohkoshi; Qian Shi; Kenneth F. Bastow; Kuo-Hsiung Lee

  Anti-AIDS agents 89. Identification of DCX derivatives as anti-HIV and chemosensitizing dual function agents to overcome P-gp-mediated drug resistance for AIDS therapy

  Bioorganic and Medicinal Chemistry Letters. 2012;22(9):3219-3222.
  0

• 8.

  2012

  Yizhou Dong; Kyoko Nakagawa-Goto; Chin-Yu Lai; Susan L. Morris-Natschke; Kenneth F. Bastow; Yoon Kim; Eva Y.-H. P. Lee; Kuo-Hsiung Lee

  Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2 H -benzo[ h ]chromen-2-one and 4-amino-7,8,9,10-tetrahydro- 2 h -benzo[ h ]chromen-2-one analogues with improved water solubility

  Journal of Natural Products. 2012;75(3):370-377.
  1

• 9.

  2012

  Koji Wada; Emika Ohkoshi; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee

  Cytotoxic esterified diterpenoid alkaloid derivatives with increased selectivity against a drug-resistant cancer cell line

  Bioorganic and Medicinal Chemistry Letters. 2012;22(1):249-252.
  1

• 10.

  2012

  M. Vijaya Bhaskar Reddy; Yuh-Chiang Shen; Emika Ohkoshi; Kenneth F. Bastow; Keduo Qian; Kuo-Hsiung Lee; Tian-Shung Wu

  Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents

  European Journal of Medicinal Chemistry. 2012;47(1):97-103.
  0

• 11.

  2011

  Xiaoming Yang; Qian Shi; Shuenn-Chen Yang; Chi-Yuan Chen; Sung-Liang Yu; Kenneth F. Bastow; Susan L. Morris-Natschke; Pei-Chi Wu; Chin-Yu Lai; Tian-Shung Wu; et al.

  Antitumor agents 288: Design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents

  Journal of Medicinal Chemistry. 2011;54(14):5097-5107.
  11

• 12.

  2011

  Sergio Rosselli; Maurizio Bruno; Antonella Maggio; Rosa Angela Raccuglia; Muhammad Safder; Chin-Yu Lai; Kenneth F. Bastow; Kuo-Hsiung Lee

  Cytotoxic geranylflavonoids from Bonannia graeca

  Phytochemistry. 2011;72(9):942-945.
  2

• 13.

  2011

  Ting-Chun Kuo; Po-Cheng Chiang; Chia-Chun Yu; Kyoko Nakagawa-Goto; Kenneth F. Bastow; Kuo-Hsiung Lee; Jih-Hwa Guh

  A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways

  Biochemical Pharmacology. 2011;81(9):1136-1144.
  4

• 14.

  2011

  Hsiu-Hui Chan; Tsong-Long Hwang; Mopur Vijaya Bhaskar Reddy; Ding-Tzai Li; Keduo Qian; Kenneth F. Bastow; Kuo-Hsiung Lee; Tian-Shung Wu

  Bioactive constituents from the roots of panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds

  Journal of Natural Products. 2011;74(4):796-802.
  4

• 15.

  2011

  Yizhou Dong; Kyoko Nakagawa-Goto; Chin-Yu Lai; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity

  Bioorganic and Medicinal Chemistry Letters. 2011;21(8):2341-2344.
  2

• 16.

  2011

  M. Vijaya Bhaskar Reddy; Yuh-Chiang Shen; Jai-Sing Yang; Tsong-Long Hwang; Kenneth F. Bastow; Keduo Qian; Kuo-Hsiung Lee; Tian-Shung Wu

  New bichalcone analogs as NF-κB inhibitors and as cytotoxic agents inducing Fas/CD95-dependent apoptosis

  Bioorganic and Medicinal Chemistry. 2011;19(6):1895-1906.
  4

• 17.

  2011

  Kyoko Nakagawa-Goto; Pei-Chi Wu; Chin-Yu Lai; Ernest Hamel; Hao Zhu; Liying Zhang; Takashi Kozaka; Emika Ohkoshi; Masuo Goto; Kenneth F. Bastow; et al.

  Antitumor agents. 284. new desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents

  Journal of Medicinal Chemistry. 2011;54(5):1244-1255.
  2

• 18.

  2011

  Kyoko Nakagawa-Goto; Pei-Chi Wu; Kenneth F. Bastow; Shuenn-Chen Yang; Sung-Liang Yu; Hsuan-Yu Chen; Jau-Chen Lin; Masuo Goto; Susan L. Morris-Natschke; Pan-Chyr Yang; et al.

  Antitumor agents 283. Further elaboration of Desmosdumotin C analogs as potent antitumor agents: Activation of spindle assembly checkpoint as possible mode of action

  Bioorganic and Medicinal Chemistry. 2011;19(5):1816-1822.
  2

• 19.

  2011

  Zehao Huang; Yan Lu; Yinan Liu; Kenneth F. Bastow; Kuohsiung Lee; Daofeng Chen

  Kadsufolins A-D and related cytotoxic lignans from Kadsura oblongifolia

  Helvetica Chimica Acta. 2011;94(3):519-527.
  0

• 20.

  2011

  Yizhou Dong; Kyoko Nakagawa-Goto; Chin-Yu Lai; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 281. Design, synthesis, and biological activity of substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogs (ATBO) as potent in vitro anticancer agents

  Bioorganic and Medicinal Chemistry Letters. 2011;21(1):546-549.
  0

• 21.

  2011

  Yizhou Dong; Kyoko Nakagawa-Goto; Chin-Yu Lai; Yoon Kim; Susan L. Morris-Natschke; Eva Y.-H.P. Lee; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 279. Structure-activity relationship and in vivo studies of novel 2-(furan-2-yl)naphthalen-1-ol (FNO) analogs as potent and selective anti-breast cancer agents

  Bioorganic and Medicinal Chemistry Letters. 2011;21(1):52-57.
  2

• 22.

  2010

  Ting Zhou; Qian Shi; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 286. Design, synthesis, and structure-activity relationships of 3'R,4'R -disubstituted-2',2'-dimethyldihydropyrano[2,3- f ]chromone (DSP) analogues as potent chemosensitizers to overcome multidrug resistance

  Journal of Medicinal Chemistry. 2010;53(24):8700-8708.
  6

• 23.

  2010

  Shwu-Jen Wu; Yann-Lii Leu; Chou-Hsiung Chen; Chih-Hua Chao; De-Yang Shen; Hsiu-Hui Chan; E-Jian Lee; Tian-Shung Wu; Yea-Hwey Wang; Yuh-Chiang Shen; et al.

  Camphoratins A-J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus

  Journal of Natural Products. 2010;73(11):1756-1762.
  8

• 24.

  2010

  Yoshihide Usami; Kyoko Nakagawa-Goto; Jing-Yu Lang; Yoon Kim; Chin-Yu Lai; Masuo Goto; Nobuko Sakurai; Masahiko Taniguchi; Toshiyuki Akiyama; Susan L. Morris-Natschke; et al.

  Antitumor agents. 282. 2′-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent

  Journal of Natural Products. 2010;73(9):1553-1558.
  6

• 25.

  2010

  Kyoko Nakagawa-Goto; Po-Cheng Chang; Chin-Yu Lai; Hsin-Yi Hung; Tzu-Hsuan Chen; Pei-Chi Wu; Hao Zhu; Alexander Sedykh; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. 280. Multidrug resistance-selective desmosdumotin B analogues

  Journal of Medicinal Chemistry. 2010;53(18):6699-6705.
  5

• 26.

  2010

  Yizhou Dong; Kyoko Nakagawa-Goto; Chin-Yu Lai; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 278. 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs as potent in vitro anti-cancer agents

  Bioorganic and Medicinal Chemistry Letters. 2010;20(14):4085-4087.
  11

• 27.

  2010

  Takashi Kozaka; Kyoko Nakagawa-Goto; Qian Shi; Chin-Yu Lai; Ernest Hamel; Kenneth F. Bastow; Arnold Brossi; Kuo-Hsiung Lee

  Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agents

  Bioorganic and Medicinal Chemistry Letters. 2010;20(14):4091-4094.
  2

• 28.

  2010

  Li-Jie Zhang; Chun-Tang Chiou; Jing-Jy Cheng; Hui-Chi Huang; Li-Ming Yang Kuo; Chia-Chin Liao; Kenneth F. Bastow; Kuo-Hsiung Lee; Yao-Haur Kuo

  Cytotoxic polyisoprenyl benzophenonoids from garcinia subelliptica

  Journal of Natural Products. 2010;73(4):557-562.
  9

• 29.

  2010

  Xiaoming Yang; Qian Shi; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. 274. A new synthetic strategy for E-ring SAR study of antofine and cryptopleurine analogues

  Organic Letters. 2010;12(7):1416-1419.
  21

• 30.

  2010

  Yizhou Dong; Qian Shi; Huei-Chen Pai; Chieh-Yu Peng; Shiow-Lin Pan; Che-Ming Teng; Kyoko Nakagawa-Goto; Donglei Yu; Yi-Nan Liu; Pei-Chi Wu; et al.

  Antitumor agents. 272. Structure-activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues

  Journal of Medicinal Chemistry. 2010;53(5):2299-2308.
  19

• 31.

  2010

  Qi Wang; Tzu-Hsuan Chen; Kenneth F. Bastow; Kuo-Hsiung Lee; Dao-Feng Chen

  Altaicalarins A-D, cytotoxic bisabolane sesquiterpenes from ligularia altaica

  Journal of Natural Products. 2010;73(2):139-142.
  4

• 32.

  2010

  Chiao-Ting Yen; Kyoko Nakagawa-Goto; Tsong-Long Hwang; Pei-Chi Wu; Susan L. Morris-Natschke; Wan-Chun Lai; Kenneth F. Bastow; Fang-Rong Chang; Yang-Chang Wu; Kuo-Hsiung Lee

  Antitumor agents. 271: Total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents

  Bioorganic and Medicinal Chemistry Letters. 2010;20(3):1037-1039.
  6

• 33.

  2010

  Yizhou Dong; Qian Shi; Kyoko Nakagawa-Goto; Pei-Chi Wu; Susan L. Morris-Natschke; Arnold Brossi; Kenneth F. Bastow; Jing-Yu Lang; Mien-Chie Hung; Kuo-Hsiung Lee

  Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents

  Bioorganic and Medicinal Chemistry. 2010;18(2):803-808.
  8

• 34.

  2010

  Sergio Rosselli; Antonella Maria Maggio; Rosa Angela Raccuglia; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee; Maurizio Bruno

  Acid rearrangment of epoxy-germacranolides and absolute configuration of 1β,10α-epoxy-salonitenolide

  Natural Product Communications. 2010;5(5):675-680.
  2

• 35.

  2010

  Yumi Nishiyama; Kinuko Iwasa; Suguru Okada; Sousuke Takeuchi; Masataka Moriyasu; Miyoko Kamigauchi; Junko Koyama; Atsuko Takeuchi; Harukuni Tokuda; Hye-Sook Kim; et al.

  Geranyl derivatives of isoquinoline alkaloids show increased biological activities

  Heterocycles. 2010;81(5):1193-1229.
  2

• 36.

  2009

  Xiaoming Yang; Qian Shi; Yi-Nan Liu; Guiyu Zhao; Kenneth F. Bastow; Jau-Chen Lin; Shuenn-Chen Yang; Pan-Chyr Yang; Kuo-Hsiung Lee

  Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents

  Journal of Medicinal Chemistry. 2009;52(16):5262-5268.
  13

• 37.

  2009

  Chung-Ren Su; Sheau Farn Yeh; Chih Miem Liu; Amooru G. Damu; Tsung-Hsiao Kuo; Po-Cheng Chiang; Kenneth F. Bastow; Kuo-Hsiung Lee; Tian-Shung Wu

  Anti-HBV and cytotoxic activities of pyranocoumarin derivatives

  Bioorganic and Medicinal Chemistry. 2009;17(16):6137-6143.
  21

• 38.

  2009

  Yizhou Dong; Qian Shi; Yi-Nan Liu; Xiang Wang; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. 266. Design, synthesis, and biological evaluation of novel 2-(furan-2-yl)naphthalen-1-ol derivatives as potent and selective antibreast cancer agents

  Journal of Medicinal Chemistry. 2009;52(11):3586-3590.
  20

• 39.

  2009

  Chia-Lin Lee; Fang-Rong Chang; Ming-Hon Yen; Donglei Yu; Yi-Nan Liu; Kenneth F. Bastow; Susan L. Morris-Natschke; Yang-Chang Wu; Kuo-Hsiung Lee

  Cytotoxic phenanthrenequinones and 9,10-dihydrophenanthrenes from Calanthe arisanensis

  Journal of Natural Products. 2009;72(2):210-213.
  5

• 40.

  2009

  Kinuko Iwasa; Suguru Okada; Yumi Nishiyama; Sousuke Takeuchi; Masataka Moriyasu; Chisato Tode; Makiko Sugiura; Atsuko Takeuchi; Harukuni Tokuda; Kazuyoshi Takeda; et al.

  Geranyl derivatives of salsolinol show increased biological activities

  Heterocycles. 2009;77(2):1355-1369.
  1

• 41.

  2009

  Sergio Rosselli; Antonella Maria Maggio; Nicoletta Faraone; Vivienne Spadaro; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee; Maurizio Bruno

  The cytotoxic properties of natural coumarins isolated from roots of Ferulago campestris (Apiaceae) and of synthetic ester derivatives of aegelinol

  Natural Product Communications. 2009;4(12):1701-1706.
  7

• 42.

  2009

  Yizhou Dong; Qian Shi; Kyoko Nakagawa-Goto; Pei-Chi Wu; Kenneth F. Bastow; Susan L. Morris-Natschke; Kuo-Hsiung Lee

  Antitumor agents 269. Non-aromatic ring-A neotanshinlactone analog, TNO, as a new class of potent antitumor agents

  Bioorganic and Medicinal Chemistry Letters. 2009;19(22):6289-6292.
  12

• 43.

  2008

  Gang Wu; Huan-Fang Guo; Kun Gao; Yi-Nan Liu; Kenneth F. Bastow; Susan L. Morris-Natschke; Kuo-Hsiung Lee; Lan Xie

  Synthesis of unsymmetrical biphenyls as potent cytotoxic agents

  Bioorganic and Medicinal Chemistry Letters. 2008;18(19):5272-5276.
  10

• 44.

  2008

  Chia-Lin Lee; Kyoko Nakagawa-Goto; Donglei Yu; Yi-Nan Liu; Kenneth F. Bastow; Susan L. Morris-Natschke; Fang-Rong Chang; Yang-Chang Wu; Kuo-Hsiung Lee

  Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis

  Bioorganic and Medicinal Chemistry Letters. 2008;18(15):4275-4277.
  7

• 45.

  2008

  M. Vijaya Bhaskar Reddy; Chung-Ren Su; Wen-Fei Chiou; Yi-Nan Liu; Rosemary Yin-Hwa Chen; Kenneth F. Bastow; Kuo-Hsiung Lee; Tian-Shung Wu

  Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents

  Bioorganic and Medicinal Chemistry. 2008;16(15):7358-7370.
  28

• 46.

  2008

  Kyoko Nakagawa-Goto; Kenneth F. Bastow; Tzu-Hsuan Chen; Susan L. Morris-Natschke; Kuo-Hsiung Lee

  Antitumor agents 260. New desmosdumotin B analogues with improved in vitro anticancer activity

  Journal of Medicinal Chemistry. 2008;51(11):3297-3303.
  10

• 47.

  2008

  Chung-Ren Su; Amooru G. Damu; Po-Cheng Chiang; Kenneth F. Bastow; Susan L. Morris-Natschke; Kuo-Hsiung Lee; Tian-Shung Wu

  Total synthesis of phenanthroindolizidine alkaloids (±)-antofine, (±)-deoxypergularinine, and their dehydro congeners and evaluation of their cytotoxic activity

  Bioorganic and Medicinal Chemistry. 2008;16(11):6233-6241.
  12

• 48.

  2008

  Chieh-Yu Peng; Shiow-Lin Pan; Kuo-Hsiung Lee; Kenneth F. Bastow; Che-Ming Teng

  Molecular mechanism of the inhibitory effect of KS-5 on bFGF-induced angiogenesis in vitro and in vivo

  Cancer Letters. 2008;263(1):114-121.
  5

• 49.

  2008

  Yoshihide Usami; Yi-Nan Liu; An-Shen Lin; Makro Shibano; Toshiyuki Akiyama; Hideji Itokawa; Susan L. Morris-Natschke; Kenneth Bastow; Ryoji Kasai; Kuo-Hsiung Lee

  Antitumor agents. 261. 20(S)-protopanaxadiol and 20(S)-protopanaxatriol as antiangiogenic agents and total assignment of ¹H NMR spectra

  Journal of Natural Products. 2008;71(3):478-481.
  19

• 50.

  2008

  Linyi Wei; Arnold Brossi; Susan L. Morris-Natschke; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 248. Chemistry and antitumor activity of tylophorinerelated alkaloids

  Studies in Natural Products Chemistry. 2008;34(C):3-34.
  6

• 51.

  2007

  Kyoko Nakagawa-Goto; Koji Yamada; Seikou Nakamura; Tzu-Hsuan Chen; Po-Cheng Chiang; Kenneth F. Bastow; Shao-Chun Wang; Bill Spohn; Mien-Chie Hung; Fang-Yu Lee; et al.

  Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant-taxoid conjugates as novel cytotoxic agents

  Bioorganic and Medicinal Chemistry Letters. 2007;17(18):5204-5209.
  17

• 52.

  2007

  Jin Tatsuzaki; Masahiko Taniguchi; Kenneth F. Bastow; Kyoko Nakagawa-Goto; Susan L. Morris-Natschke; Hideji Itokawa; Kimiye Baba; Kuo-Hsiung Lee

  Anti-tumor agents 255: Novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents

  Bioorganic and Medicinal Chemistry. 2007;15(18):6193-6199.
  29

• 53.

  2007

  Li-Bo Zhou; Tzu-Hsuan Chen; Kenneth F. Bastow; Makio Shibano; Kuo-Hsiung Lee; Dao-Feng Chen

  Filiasparosides A-D, cytotoxic steroidal saponins from the roots of Asparagus filicinus

  Journal of Natural Products. 2007;70(8):1263-1267.
  12

• 54.

  2007

  Linyi Wei; Qian Shi; Kenneth F. Bastow; Arnold Brossi; Susan L. Morris-Natschke; Kyoko Nakagawa-Goto; Tian-Shung Wu; Shiow-Lin Pan; Che-Ming Teng; Kuo-Hsiung Lee

  Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents

  Journal of Medicinal Chemistry. 2007;50(15):3674-3680.
  22

• 55.

  2007

  Kyoko Nakagawa-Goto; Tzu-Hsuan Chen; Chieh-Yu Peng; Kenneth F. Bastow; Jiu-Hong Wu; Kuo-Hsiung Lee

  Antitumor agents 259. Design, syntheses, and structure-activity relationship study of desmosdumotin C analogs

  Journal of Medicinal Chemistry. 2007;50(14):3354-3358.
  6

• 56.

  2007

  Amooru G. Damu; Ping-Chung Kuo; Chung-Ren Su; Tsung-Hsiao Kuo; Tzu-Hsuan Chen; Kenneth F. Bastow; Kuo-Hsiung Lee; Tian-Shung Wu

  Isolation, structures, and structure-cytotoxic activity relationships of withanolides and physalins from Physalis angulata

  Journal of Natural Products. 2007;70(7):1146-1152.
  32

• 57.

  2007

  Kyoko Nakagawa-Goto; Seikou Nakamura; Kenneth F. Bastow; Alexander Nyarko; Chieh-Yu Peng; Fang-Yu Lee; Fang-Chen Lee; Kuo-Hsiung Lee

  Antitumor agents. 256. Conjugation of paclitaxel with other antitumor agents: Evaluation of novel conjugates as cytotoxic agents

  Bioorganic and Medicinal Chemistry Letters. 2007;17(10):2894-2898.
  20

• 58.

  2007

  Sergio Rosselli; Maurizio Bruno; Antonella Maggio; Gabriella Bellone; Tzu-Hsuan Chen; Kenneth F. Bastow; Kuo-Hsiung Lee

  Cytotoxic activity of some natural and synthetic ent-kauranes

  Journal of Natural Products. 2007;70(3):347-352.
  8

• 59.

  2007

  Masafumi Horiuch; Chihiro Murakami; Narihiko Fukamiya; Donglei Yu; Tzu-Hsuan Chen; Kenneth F. Bastow; De-Cheng Zhang; Yoshihisa Takaishi; Yasuhiro Imakura; Kuo-Hsiung Lee

  Erratum: Tripfordines A-C, sesquiterpene pyridine alkaloids from Tripterygium wilfordii, and structure anti-HIV activity relationships of Tripterygium alkaloids (Journal of Natural Products (2006) 69)

  Journal of Natural Products. 2007;70(1):142.
  0

• 60.

  2007

  Shuxing Zhang; Linyi Wei; Ken Bastow; Weifan Zheng; Arnold Brossi; Kuo-Hsiung Lee; Alexander Tropsha

  Antitumor agents 252. Application of validated QSAR models to database mining: Discovery of novel tylophorine derivatives as potential anticancer agents

  Journal of Computer-Aided Molecular Design. 2007;21(1-3):97-112.
  44

• 61.

  2006

  Pei-Lin Wu; Yu-Lin Hsu; Tian-Shung Wu; K.F. Bastow; Kuo-Hsiung Lee

  Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis

  Organic Letters. 2006;8(23):5207-5210.
  17

• 62.

  2006

  Jin Tatsuzaki; Kenneth F. Bastow; Kyoko Nakagawa-Goto; Seiko Nakamura; Hideji Itokawa; Kuo-Hsiung Lee

  Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents

  Journal of Natural Products. 2006;69(10):1445-1449.
  17

• 63.

  2006

  Linyi Wei; Arnold Brossi; Ross Kendall; Kenneth F. Bastow; Susan L. Morris-Natschke; Qian Shi; Kuo-Hsiung Lee

  Antitumor agents 251: Synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents

  Bioorganic and Medicinal Chemistry. 2006;14(19):6560-6569.
  37

• 64.

  2006

  Xihong Wang; Kyoko Nakagawa-Goto; Kenneth F. Bastow; Ming-Jaw Don; Yun-Lian Lin; Tian-Shung Wu; Kuo-Hsiung Lee

  Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents

  Journal of Medicinal Chemistry. 2006;49(18):5631-5634.
  21

• 65.

  2006

  Masafumi Horiuch; Chihiro Murakami; Narihiko Fukamiya; Donglei Yu; Tzu-Hsuan Chen; Kenneth F. Bastow; De-Cheng Zhang; Yoshihisa Takaishi; Yasuhiro Imakura; Kuo-Hsiung Lee

  Tripfordines A-C, sesquiterpene pyridine alkaloids from Tripterygium wilfordii, and structure anti-HIV activity relationships of Tripterygium alkaloids

  Journal of Natural Products. 2006;69(9):1271-1274.
  16

• 66.

  2006

  Ping-Chung Kuo; Tsung-Hsiao Kuo; Amooru G. Damu; Chung-Ren Su; E.-Jian Lee; Tian-Shung Wu; Rexen Shu; Chou-Ming Chen; Kenneth F. Bastow; Tzu-Hsuan Chen; et al.

  Physanolide A, a novel skeleton steroid, and other cytotoxic principles from Physalis angulata

  Organic Letters. 2006;8(14):2953-2956.
  26

• 67.

  2006

  Li Lin; Qian Shi; Alexander K. Nyarko; Kenneth F. Bastow; Chin-Chung Wu; Ching-Yuan Su; Charles C.-Y. Shih; Kuo-Hsiung Lee

  Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents

  Journal of Medicinal Chemistry. 2006;49(13):3963-3972.
  63

• 68.

  2006

  Nobuko Sakurai; Kyoko Nakagawa-Goto; Junko Ito; Yojiro Sakurai; Yuka Nakanishi; Kenneth F. Bastow; Gordon Cragg; Kuo-Hsiung Lee

  Cytotoxic Alangium alkaloids from Alangium longiflorum

  Phytochemistry. 2006;67(9):894-897.
  4

• 69.

  2006

  Pannarat Akanitapichat; Aree Wangmaneerat; Prapon Wilairat; Kenneth F. Bastow

  Anti-herpes virus activity of Dunbaria bella Prain

  Journal of Ethnopharmacology. 2006;105(1-2):64-68.
  10

• 70.

  2006

  Yojiro Sakurai; Nobuko Sakurai; Masahiko Taniguchi; Yuka Nakanishi; Kenneth F. Bastow; Xihong Wang; Gordon M. Cragg; Kuo-Hsiung Lee

  Rautandiols A and B, pterocarpans and cytotoxic constituents from Neorautanenia mitis

  Journal of Natural Products. 2006;69(3):397-399.
  12

• 71.

  2006

  Yang-Hua Yi; Qiang-Zhi Xu; Ling Li; Shi-Long Zhang; Hou-Ming Wu; Jian Ding; Yun-Guang Tong; Wen-Fu Tan; Mei-Hong Li; Fang Tian; et al.

  Philinopsides A and B, two new sulfated triterpene glycosides from the sea cucumber Pentacta quadrangularis

  Helvetica Chimica Acta. 2006;89(1):54-63.
  19

• 72.

  2005

  Maurizio Bruno; Sergio Rosselli; Antonella Maggio; Rosa Angela Raccuglia; Kenneth F. Bastow; Chin-Chung Wu; Kuo-Hsiung Lee

  Cytotoxic activity of some natural and synthetic sesquiterpene lactones

  Planta Medica. 2005;71(12):1176-1178.
  14

• 73.

  2005

  Seikou Nakamura; Mutsuo Kozuka; Kenneth F. Bastow; Harukuni Tokuda; Hoyoku Nishino; Madoka Suzuki; Jin Tatsuzaki; Susan L. Morris Natschke; Sheng-Chu Kuo; Kuo-Hsiung Lee

  Cancer preventive agents, Part 2: Synthesis and evaluation of 2-phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives as novel antitumor promoters

  Bioorganic and Medicinal Chemistry. 2005;13(14):4396-4401.
  26

• 74.

  2005

  Maurizio Bruno; Sergio Rosselli; Antonella Maggio; Rosa Angela Raccuglia; Kenneth F. Bastow; Kuo-Hsiung Lee

  Cytotoxic activity of some natural and synthetic guaianolides

  Journal of Natural Products. 2005;68(7):1042-1046.
  21

• 75.

  2005

  Kyoko Nakagawa-Goto; Kenneth F. Bastow; Jiu-Hong Wu; Harukuni Tokuda; Kuo-Hsiung Lee

  Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs

  Bioorganic and Medicinal Chemistry Letters. 2005;15(12):3016-3019.
  9

• 76.

  2005

  Kyoko Nakagawa-Goto; Jiu-Hong Wu; Kenneth F. Bastow; Chin-Chung Wu; Kuo-Hsiung Lee

  Antitumor agents 243. Syntheses and cytotoxicity of desmosdumotin C derivatives

  Bioorganic and Medicinal Chemistry. 2005;13(6):2325-2330.
  11

• 77.

  2005

  Kyoko Nakagawa-Goto; M. Katherine Jung; Ernest Hamel; Chin-Chung Wu; Kenneth F. Bastow; Arnold Brossi; Shunsaku Ohta; Kuo-Hsiung Lee

  Antitumor agents 238. Anti-tubulin and in vitrocytotoxic effects of N-substituted allocolchicinoids

  Heterocycles. 2005;65(3):541-550.
  12

• 78.

  2005

  Ya-Yun Lai; Li-Jiau Huang; Kuo-Hsiung Lee; Zhiyan Xiao; Kenneth F. Bastow; Takao Yamori; Sheng-Chu Kuo

  Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents

  Bioorganic and Medicinal Chemistry. 2005;13(1):265-275.
  37

• 79.

  2005

  Kyoko Nakagawa-Goto; Cyril X. Chen; Ernest Hamel; Chin-Chung Wu; Kenneth F. Bastow; Arnold Brossi; Kuo-Hsiung Lee

  Antitumor agents. Part 236: Synthesis of water-soluble colchicine derivatives

  Bioorganic and Medicinal Chemistry Letters. 2005;15(1):235-238.
  13

• 80.

  2004

  Ken F. Bastow

  New acridone inhibitors of human herpes virus replication

  Current Drug Targets - Infectious Disorders. 2004;4(4):323-330.
  13

• 81.

  2004

  Xihong Wang; Kenneth F. Bastow; Chang-Ming Sun; Yun-Lian Lin; Hsi-Jung Yu; Ming-Jaw Don; Tian-Shung Wu; Seikou Nakamura; Kuo-Hsiung Lee

  Antitumor agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza

  Journal of Medicinal Chemistry. 2004;47(23):5816-5819.
  68

• 82.

  2004

  Naonobu Tanaka; Yoshihisa Takaishi; Yasuhiro Shikishima; Yuka Nakanishi; Kenneth Bastow; Kuo-Hsiung Lee; Gisho Honda; Michiho Ito; Yoshio Takeda; Olimjon K. Kodzhimatov; et al.

  Prenylated benzophenones and xanthones from Hypericum scabrum

  Journal of Natural Products. 2004;67(11):1870-1875.
  47

• 83.

  2004

  Chih-Chuang Liaw; Fang-Rong Chang; Yang-Chang Wu; Hui-Kang Wang; Yuka Nakanishi; Kenneth F. Bastow; Kuo-Hsiung Lee

  Montacin and cis-montacin, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona montana

  Journal of Natural Products. 2004;67(11):1804-1808.
  8

• 84.

  2004

  Zhiyan Xiao; Kenneth F. Bastow; John R. Vance; Robert S. Sidwell; Hui-Kang Wang; Ming S. Chen; Qian Shi; Kuo-Hsiung Lee

  Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4β-[(4″-benzamido)-amino]-4′-O-demethyl- epipodophyllotoxin derivatives

  Journal of Medicinal Chemistry. 2004;47(21):5140-5148.
  22

• 85.

  2004

  Chih-Chuang Liaw; Fang-Rong Chang; Chin-Chung Wu; Shu-Li Chen; Kenneth F. Bastow; Ken-Ichiro Hayashi; Hiroshi Nozaki; Kuo-Hsiung Lee; Yang-Chang Wu

  Nine new cytotoxic monotetrahydrofuranic annonaceous acetogenins from Annona montana

  Planta Medica. 2004;70(10):948-959.
  13

• 86.

  2004

  Chihiro Murakami; Narihiko Fukamiya; Sadaaki Tamura; Masayoshi Okano; Kenneth F. Bastow; Harukuni Tokuda; Teruo Mukainaka; Hoyoky Nishino; Kuo-Hsiung Lee

  Multidrug-resistant cancer cell susceptibility to cytotoxic quassinoids, and cancer chemopreventive effects of quassinoids and canthin alkaloids

  Bioorganic and Medicinal Chemistry. 2004;12(18):4963-4968.
  23

• 87.

  2004

  Naonobu Tanaka; Nobuyuki Ooba; Hongquan Duan; Yoshihisa Takaishi; Yuka Nakanishi; Kenneth Bastow; Kuo-Hsiung Lee

  Kaurane and abietane diterpenoids from Tripterygium doianum (Celastraceae)

  Phytochemistry. 2004;65(14):2071-2076.
  12

• 88.

  2004

  Zhiyan Xiao; John R. Vance; Kenneth F. Bastow; Arnold Brossi; Hui-Kang Wang; Kuo-Hsiung Lee

  Antitumor agents. Part 235: Novel 4′-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential

  Bioorganic and Medicinal Chemistry. 2004;12(12):3363-3369.
  13

• 89.

  2004

  Zhiyan Xiao; Kenneth F. Bastow; John R. Vance; Kuo-Hsiung Lee

  Antitumor agents. Part 227: Studies on novel 4′-O-demethyl- epipodophyllotoxins as antitumor agents targeting topoisomerase II

  Bioorganic and Medicinal Chemistry. 2004;12(12):3339-3344.
  11

• 90.

  2004

  Shiqing Han; Zhiyan Xiao; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. Part 230: C_4′-esters of GL-331 as cytotoxic agents and DNA topoisomerase II inhibitors

  Bioorganic and Medicinal Chemistry Letters. 2004;14(11):2979-2982.
  5

• 91.

  2004

  Ken-Ichiro Hayashi; Fang-Rong Chang; Yuka Nakanishi; Kenneth F. Bastow; Gordon Cragg; Andrew T. McPhail; Hiroshi Nozaki; Kuo-Hsiung Lee

  Antitumor agents. 233.¹ Lantalucratins A-F, new cytotoxic naphthoquinones from Lantana involucrata

  Journal of Natural Products. 2004;67(6):990-993.
  7

• 92.

  2004

  Yong-Hong Wang; Ai-Jun Hou; Lei Chen; Dao-Feng Chen; Han-Dong Sun; Qin-Shi Zhao; Kenneth F. Bastow; Yuka Nakanish; Xi-Hong Wang; Kuo-Hsiung Lee

  New isoprenylated flavones, artochamins A-E, and cytotoxic principles from Artocarpus chama

  Journal of Natural Products. 2004;67(5):757-761.
  46

• 93.

  2004

  Zhiyan Xiao; Shiqing Han; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. Part 232: Synthesis of cyclosulfite podophyllotoxin analogues as novel prototype antitumor agents

  Bioorganic and Medicinal Chemistry Letters. 2004;14(6):1581-1584.
  8

• 94.

  2004

  Peilan Ding; Daofeng Chen; Kenneth F. Bastow; Alexander K. Nyarko; Xihong Wang; Kuo-Hsiung Lee

  Cytotoxic isoprenylated flavonoids from the roots of Sophora flavescens

  Helvetica Chimica Acta. 2004;87(10):2574-2580.
  18

• 95.

  2003

  Christopher T. Lowden; Kenneth F. Bastow

  Anti-Herpes Simplex Virus Activity of Substituted 1-Hydroxyacridones

  Journal of Medicinal Chemistry. 2003;46(23):5015-5020.
  9

• 96.

  2003

  Fang-Rong Chang; Ken-Ichiro Hayashi; I-Hsiao Chen; Chih-Chuang Liaw; Kenneth F. Bastow; Yuka Nakanishi; Hiroshi Nozaki; Gordon M. Cragg; Yang-Chang Wu; Kuo-Hsiung Lee

  Antitumor Agents. 228. Five New Agarofurans, Reissantins A-E, and Cytotoxic Principles from Reissantia buchananii

  Journal of Natural Products. 2003;66(11):1416-1420.
  43

• 97.

  2003

  Ping-Chung Kuo; Li-Shian Shi; Amooru G. Damu; Chung-Ren Su; Chieh-Hung Huang; Chih-Huang Ke; Jin-Bin Wu; Ai-Jeng Lin; Kenneth F. Bastow; Kuo-Hsiung Lee; et al.

  Cytotoxic and Antimalarial β-Carboline Alkaloids from the Roots of Eurycoma longifolia

  Journal of Natural Products. 2003;66(10):1324-1327.
  57

• 98.

  2003

  Yi Xia; Zheng-Yu Yang; Peng Xia; Kenneth F. Bastow; Yuka Nakanishi; Priya Nampoothiri; Ernest Hamel; Arnold Brossi; Kuo-Hsiung Lee

  Antitumor agents. Part 226: Synthesis and cytotoxicity of 2-phenyl-4-quinolone acetic acids and their esters

  Bioorganic and Medicinal Chemistry Letters. 2003;13(17):2891-2893.
  35

• 99.

  2003

  C.T. Lowden; K.F. Bastow

  Cell culture replication of herpes simplex virus and, or human cytomegalovirus is inhibited by 3,7-dialkoxylated, 1-hydroxyacridone derivatives

  Antiviral Research. 2003;59(3):143-154.
  17

• 100.

  2003

  Masayoshi Oyama; Kenneth F. Bastow; Yoko Tachibana; Yoshiaki Shirataki; Sadaki Yamaguchi; Gordon M. Cragg; Tian-Shung Wu; Kuo-Hsiung Lee

  Antitumor agents 225. Acrofoliones A and B, two novel cytotoxic acetophenone dimers, from Acronychia trifoliolata

  Chinese Pharmaceutical Journal. 2003;55(4):239-245.
  2

• 101.

  2003

  Yuka Nakanishi; Fang-Rong Chang; Chih-Chuang Liaw; Yang-Chang Wu; Kenneth F. Bastow; Kuo-Hsiung Lee

  Acetogenins as selective inhibitors of the human ovarian 1A9 tumor cell line

  Journal of Medicinal Chemistry. 2003;46(15):3185-3188.
  25

• 102.

  2003

  Jiu-Hong Wu; Fang-Rong Chang; Ken-Ichiro Hayashi; Hiroaki Shiraki; Chih-Chuang Liaw; Yuka Nakanishi; Kenneth F. Bastow; Donglei Yu; Ih-Sheng Chen; et al.

  Antitumor agents. Part 218: Cappamensin A, a new in vitro anticancer principle, from Capparis sikkimensis

  Bioorganic and Medicinal Chemistry Letters. 2003;13(13):2223-2225.
  12

• 103.

  2003

  Hironori Ohtsu; Yuka Nakanishi; Kenneth F. Bastow; Fang-Yu Lee; Kuo-Hsiung Lee

  Antitumor agents 216. Synthesis and evaluation of paclitaxel-camptothecin conjugates as novel cytotoxic agents

  Bioorganic and Medicinal Chemistry. 2003;11(8):1851-1857.
  20

• 104.

  2003

  Qian Zhang; Ying Chen; Yun Qing Zheng; Peng Xia; Yi Xia; Zheng Yu Yang; Kenneth F. Bastow; Susan L. Morris-Natschke; Kuo-Hsiung Lee

  Synthesis and bioactivity of 4,10-dimethyl-pyridino[2,3-h]quinolin-2(1H)-one-9-carboxylic acid and its esters

  Bioorganic and Medicinal Chemistry. 2003;11(6):1031-1034.
  8

• 105.

  2003

  Ken-ichiro Hayashi; Yuka Nakanishi; Kenneth F. Bastow; Gordon Cragg; Hiroshi Nozaki; Kuo-Hsiung Lee

  Antitumor agents. 221. Buceracidins A and B, two new flavanones from Bucida buceras

  Journal of Natural Products. 2003;66(1):125-127.
  11

• 106.

  2002

  Junko Ishida; Hironori Ohtsu; Yoko Tachibana; Yuka Nakanishi; Kenneth F Bastow; Masahiro Nagai; Hui-Kang Wang; Hideji Itokawa; Kuo-Hsiung Lee

  Antitumor agents. Part 214: Synthesis and evaluation of curcumin analogues as cytotoxic agents

  Bioorganic and Medicinal Chemistry. 2002;10(11):3481-3487.
  78

• 107.

  2002

  Shiqing Han; Ernest Hamel; Kenneth F. Bastow; Andrew T. McPhail; Arnold Brossi; Kuo-Hsiung Lee

  Antitumor agents. Part 215: Antitubulin effects of cytotoxic B-Ring modified allocolchicinoids

  Bioorganic and Medicinal Chemistry Letters. 2002;12(20):2851-2853.
  5

• 108.

  2002

  Youichi Shinozaki; Narihiko Fukamiya; Chieko Uchiyama; Masayoshi Okano; Kiyoshi Tagahara; Kenneth F Bastow; Kuo-Hsiung Lee

  Multidrug resistant cancer cells susceptibility to cytotoxic taxane diterpenes from Taxus yunnanensis and Taxus chinensis

  Bioorganic and Medicinal Chemistry Letters. 2002;12(19):2785-2788.
  6

• 109.

  2002

  Jiu-Hong Wu; Andrew T. McPhail; Kenneth F. Bastow; Hiroaki Shiraki; Junko Ito; Kuo-Hsiung Lee

  Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus

  Tetrahedron Letters. 2002;43(8):1391-1393.
  18

• 110.

  2002

  Ken-Ichiro Hayashi; Yuka Nakanishi; Kenneth F. Bastow; Gordon Cragg; Hiroshi Nozaki; Kuo-Hsiung Lee

  Antitumor agents. Part 212: Bucidarasins A-C, three new cytotoxic clerodane diterpenes from Bucida buceras

  Bioorganic and Medicinal Chemistry Letters. 2002;12(3):345-348.
  16

• 111.

  2002

  P Akanitapichat; K.F Bastow

  The antiviral agent 5-chloro-1,3-dihydroxyacridone interferes with assembly and maturation of herpes simplex virus

  Antiviral Research. 2002;53(2):113-126.
  23

• 112.

  2002

  Prapai Wongsinkongman; Arnold Brossi; Hui-Kang Wang; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. Part 209: Pheophorbide-a derivatives as photo-independent cytotoxic agents

  Bioorganic and Medicinal Chemistry. 2002;10(3):583-591.
  29

• 113.

  2001

  Y. Na; V.-S. Li; Y. Nakanishi; K.F. Bastow; H. Kohn

  Synthesis, DNA cross-linking activity, and cytotoxicity of dimeric mitomycins

  Journal of Medicinal Chemistry. 2001;44(21):3453-3462.
  18

• 114.

  2001

  Tetsuro Ito; Toshiyuki Tanaka; Ken-Ichi Nakaya; Munekazu Iinuma; Yoshikazu Takahashi; Hiroshi Naganawa; Masayoshi Ohyama; Yuka Nakanishi; Kenneth F. Bastow; Kuo-Hsiung Lee

  A new resveratrol octamer, vateriaphenol A, in Vateria indica

  Tetrahedron Letters. 2001;42(34):5909-5912.
  21

• 115.

  2001

  Tetsuro Ito; Toshiyuki Tanaka; Ken-Ichi Nakaya; Munekazu Iinuma; Yoshikazu Takahashi; Hiroshi Naganawa; Masayoshi Ohyama; Yuka Nakanishi; Kenneth F Bastow; Kuo-Hsiung Lee

  A novel bridged stilbenoid trimer and four highly condensed stilbenoid oligomers in Vatica rassak

  Tetrahedron. 2001;57(34):7309-7321.
  41

• 116.

  2001

  Yi Xia; Zheng-Yu Yang; Mann-Jen Hour; Sheng-Chu Kuo; Peng Xia; Kenneth F Bastow; Yuka Nakanishi; Priya Nampoothiri; Torben Hackl; et al.

  Antitumor agents. Part 204: Synthesis and biological evaluation of substituted 2-aryl quinazolinones

  Bioorganic and Medicinal Chemistry Letters. 2001;11(9):1193-1196.
  101

• 117.

  2001

  D.S. VanVliet; Y. Tachibana; K.F. Bastow; E.-S. Huang; K.-H. Lee

  Antitumor agents. 207. Design, synthesis, and biological testing of 4β-anilino-2-fluoro-4′-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents

  Journal of Medicinal Chemistry. 2001;44(9):1422-1428.
  47

• 118.

  2001

  P. Krishnan; K.F. Bastow

  Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives α-lapachone and β-lapachone

  Cancer Chemotherapy and Pharmacology. 2001;47(3):187-198.
  36

• 119.

  2001

  Kinuko Iwasa; Masataka Moriyasu; Yoko Tachibana; Hye-Sook Kim; Yusuke Wataya; Wolfgang Wiegrebe; Kenneth F Bastow; L.Mark Cosentino; Mutsuo Kozuka; et al.

  Simple isoquinoline and benzylisoquinoline alkaloids as potential antimicrobial, antimalarial, cytotoxic, and anti-HIV agents

  Bioorganic and Medicinal Chemistry. 2001;9(11):2871-2884.
  40

• 120.

  2001

  H.-H. Cheng; H.-K. Wang; J. Ito; K.F. Bastow; Y. Tachibana; Y. Nakanishi; Z. Xu; T.-Y. Luo; K.-H. Lee

  Cytotoxic pheophorbide-related compounds from Clerodendrum calamitosum and C. cyrtophyllum

  Journal of Natural Products. 2001;64(7):915-919.
  40

• 121.

  2001

  Lallan Mishra; Ragini Sinha; Hideji Itokawa; Kenneth F Bastow; Yoko Tachibana; Yuka Nakanishi; Nicole Kilgore; Kuo-Hsiung Lee

  Anti-HIV and cytotoxic activities of Ru(II)/Ru(III) polypyridyl complexes containing 2,6-(2′-benzimidazolyl)-pyridine/chalcone as co-ligand

  Bioorganic and Medicinal Chemistry. 2001;9(7):1667-1671.
  34

• 122.

  2001

  Qian Shi; Hui-Kang Wang; Kenneth F Bastow; Yoko Tachibana; Ke Chen; Fang-Yu Lee; Kuo-Hsiung Lee

  Antitumor agents 210. synthesis and evaluation of taxoid-epipodophyllotoxin conjugates as novel cytotoxic agents

  Bioorganic and Medicinal Chemistry. 2001;9(11):2999-3004.
  34

• 123.

  2000

  M.-J. Hour; L.-J. Huang; S.-C. Kuo; Y. Xia; K. Bastow; Y. Nakanishi; E. Hamel; K.-H. Lee

  6-alkylamino- and 2,3-dihydro-3′-methoxy-2-phenyl-4-quinazolinones and related compounds: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization

  Journal of Medicinal Chemistry. 2000;43(23):4479-4487.
  146

• 124.

  2000

  Preethi Krishnan; Kenneth F. Bastow

  Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives - Eleutherin, α lapachone, and β lapachone

  Biochemical Pharmacology. 2000;60(9):1367-1379.
  59

• 125.

  2000

  Masao Fukushima; Narihiko Fukamiya; Masayoshi Okano; Tatsuo Nehira; Kiyoshi Tagahara; Shun-Xiang Zhang; De-Cheng Zhang; Yoko Tachibana; Kenneth F. Bastow; et al.

  Cytotoxity of non-alkaloidal taxane diterpenes from Taxus chinensis against a paclitaxel-resistant cell line

  Cancer Letters. 2000;158(2):151-154.
  6

• 126.

  2000

  Yi Xia; Zheng-Yu Yang; Peng Xia; Kenneth F. Bastow; Yuka Nakanishi; Kuo-Hsiung Lee

  Antitumor agents. Part 202: Novel 2'-amino chalcones: Design, synthesis and biological evaluation

  Bioorganic and Medicinal Chemistry Letters. 2000;10(8):699-701.
  94

• 127.

  2000

  Jang-Yang Chang; Xin Guo; Hong-Xing Chen; Zaoli Jiang; Qin Fu; Hui-Kang Wang; Kenneth F. Bastow; Xiao-Kang Zhu; Jian Guan; Kuo-Hsiung Lee; et al.

  Unique biochemical, cytotoxic, and antitumor activity of camptothecin and 4β-amino-4'-O-demethylepipodophyllotoxin conjugates

  Biochemical Pharmacology. 2000;59(5):497-508.
  18

• 128.

  2000

  P. Akanitapichat; C.T. Lowden; K.F. Bastow

  1,3-Dihydroxyacridone derivatives as inhibitors of herpes virus replication

  Antiviral Research. 2000;45(2):123-134.
  23

• 129.

  2000

  Yoko Tachibana; Zhu Xiao-Kang; Preethi Krishnan; Lee Kuo-Hsiung; Kenneth F. Bastow; Kf Bastow

  Characterization of human lung cancer cells resistant to 4'-O-demethyl-4β-nitro-4'-fluoroanilino)-4- desoxypodophyllotoxin, a unique compound in the epipodophyllotoxin antitumor class

  Anti-Cancer Drugs. 2000;11(1):19-28.
  4

• 130.

  2000

  P. Krishnan; K.F. Bastow

  The 9-position in berberine analogs is an important determinant of DNA topoisomerase II inhibition

  Anti-Cancer Drug Design. 2000;15(4):255-264.
  46

• 131.

  2000

  Masataka Itoigawa; Yoshiki Kashiwada; Chihiro Ito; Hiroshi Furukawa; Yoko Tachibana; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agent

  Journal of Natural Products. 2000;63(7):896-897.
  40

• 132.

  2000

  Z. Xu; F.-R. Chang; H.-K. Wang; Y. Kashiwada; A.T. McPhail; K.F. Bastow; Y. Tachibana; M. Cosentino; K.-H. Lee

  Anti-HIV agents 45¹ and antitumor agents 205.² Two new sesquiterpenes, leitneridanins A and B, and the cytotoxic and anti-HIV principles from Leitneria floridana

  Journal of Natural Products. 2000;63(12):1712-1715.
  31

• 133.

  1999

  Junko Ishida; Hui-Kang Wang; Kenneth F. Bastow; Chang-Qi Hu; Kuo-Hsiung Lee

  Antitumor agents 201. Cytotoxicity of harmine and β-carboline analogs

  Bioorganic and Medicinal Chemistry Letters. 1999;9(23):3319-3324.
  78

• 134.

  1999

  Masayoshi Ohyama; Toshiyuki Tanaka; Tetsuro Ito; Munekazu Iinuma; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives

  Bioorganic and Medicinal Chemistry Letters. 1999;9(20):3057-3060.
  60

• 135.

  1999

  Shun-Xiang Zhang; Kenneth F. Bastow; Yoko Tachibana; Sheng-Chu Kuo; Ernest Hamel; Anthony Mauger; Ven L. Narayanan; Kuo-Hsiung Lee

  Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization

  Journal of Medicinal Chemistry. 1999;42(20):4081-4087.
  54

• 136.

  1999

  John R. Vance; Kenneth F. Bastow

  Inhibition of DNA topoisomerase II catalytic activity by the antiviral agents 7-chloro-1,3-dihydroxyacridone and 1,3,7-trihydroxyacridone

  Biochemical Pharmacology. 1999;58(4):703-708.
  18

• 137.

  1999

  X.-K. Zhu; J. Guan; Y. Tachibana; K.F. Bastow; Sung Jin Cho; H. Cheng H.-; Y.-C. Cheng; M. Gurwith; K.-H. Lee

  Antitumor agents. 194. Synthesis and biological evaluations of 4-β- mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles

  Journal of Medicinal Chemistry. 1999;42(13):2441-2446.
  47

• 138.

  1999

  Zheng-Yu Yang; Yi Xia; Peng Xia; Yoko Tachibana; Kenneth F. Bastow; Kuo-Hsiung Lee

  Antitumor agents 187: Synthesis and cytotoxicity of substituted 8,8- dimethyl-2H,8H-pyrano[6,5-h]quinoline-2-one and related compounds

  Bioorganic and Medicinal Chemistry Letters. 1999;9(5):713-716.
  13

• 139.

  1999

  Jian Guan; Xiao-Kang Zhu; Arnold Brossi; Yoko Tachibana; Kenneth F. Bastow; Pascal Verdier-Pinard; Ernest Hamel; Andrew T. McPhail; Kuo-Hsiung Lee

  Antitumor agents. 192. Antitubulin effect and cytotoxicity of C(7)-oxygenated allocolchicinoids

  Collection of Czechoslovak Chemical Communications. 1999;64(2):217-228.
  16

• 140.

  1999

  Iris H. Hall; Ken F. Bastow; Amy E. Warren; Cheryl R. Barnes; Gilles M. Bouet

  Cytotoxicity of cobalt complexes of furan oximes in murine and human tissue-cultured cell lines

  Applied Organometallic Chemistry. 1999;13(11):819-828.
  13

• 141.

  1998

  Jian Guan; Xiao-Kang Zhu; Yoko Tachibana; Kenneth F. Bastow; Arnold Brossi; Ernest Hamel; Kuo-Hsiung Lee

  Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors

  Bioorganic and Medicinal Chemistry. 1998;6(11):2127-2131.
  6

• 142.

  1998

  Jian Guan; Xiao-Kang Zhu; Yoko Tachibana; Kenneth F. Bastow; Arnold Brossi; Ernest Hamel; Kuo-Hsiung Lee

  Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors

  Journal of Medicinal Chemistry. 1998;41(11):1956-1961.
  15

• 143.

  1998

  Merrill C. Miller; Kenneth F. Bastow III; Christa N. Stineman; John R. Vance; Sun C. Song; Douglas X. West; Iris H. Hall

  The cytotoxicity of 2-formyl and 2-acetyl-(6-picolyl)-⁴N-substituted thiosemicarbazones and their copper(II) complexes

  Archiv der Pharmazie. 1998;331(4):121-127.
  39

• 144.

  1998

  Yi Xia; Zheng-Yu Yang; Peng Xia; Kenneth F. Bastow; Yoko Tachibana; Sheng-Chu Kuo; Ernest Hamel; Torben Hackl; Kuo-Hsiung Lee

  Antitumor agents. 181. Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents

  Journal of Medicinal Chemistry. 1998;41(7):1155-1162.
  136

• 145.

  1997

  Hidemitsu Hara; Naoki Maruyama; Shinsuke Yamashita; Yasuhisa Hayashi; Kuo-Hsiung Lee; Kenneth F. Bastow; Chairul; Ryuji Marumoto; Yasuhiro Imakura

  Elecanacin, a novel new naphthoquinone from the bulb of Eleutherine americana

  Chemical and Pharmaceutical Bulletin. 1997;45(10):1714-1716.
  30

• 146.

  1997

  Kenneth F. Bastow; Hui-Kang Wang; Yung-Chi Cheng; Kuo-Hsiung Lee

  Antitumor Agents-CLXXIII. Synthesis and evaluation of camptothecin-4β-amino-4'-O-demethyl epipodophyllotoxin conjugates as inhibitors of mammalian DNA topoisomerases and as cytotoxic agents

  Bioorganic and Medicinal Chemistry. 1997;5(8):1481-1488.
  32

• 147.

  1997

  Barry Goz; Kenneth F. Bastow

  A possible role for topoisomerase II in cell death and N-phosphonoacetyl-L-aspartate-resistance frequency and its enhancement by 1-β-D-arabinofuranosyl cytosine and 5-fluoro-2'-deoxyuridine

  Mutation Research - DNA Repair. 1997;384(2):89-144.
  5

• 148.

  1997

  Zheng Ji; Hui-Kang Wang; Kenneth F. Bastow; Xiao-Kang Zhu; Sung Jin Cho; Yung-Chi Cheng; Kuo-Hsiung Lee

  Antitumor agents. 177. Design, syntheses, and biological evaluation of novel etoposide analogs bearing pyrrolecarboxamidino group as DNA topoisomerase II inhibitors

  Bioorganic and Medicinal Chemistry Letters. 1997;7(5):607-612.
  24

• 149.

  1997

  Merrill C. Miller III; Anup Sood; Bernard F. Spielvogel; Ken Bastow; Iris H. Hall

  Cytotoxic action of carboxyborane heterocyclic amine adducts

  Metal-Based Drugs. 1997;4(4):229-241.
  4

• 150.

  1996

  Hui-Kang Wang; Kenneth F. Bastow; L. Mark Cosentino; Kuo-Hsiung Lee

  Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones

  Journal of Medicinal Chemistry. 1996;39(10):1975-1980.
  39

• 151.

  1996

  Sung Jin Cho; Yoshiki Kashiwada; Kenneth F. Bastow; Yung-Chi Cheng; Kuo-Hsiung Lee

  Antitumor agents. 164. Podophenazine, 2″,3″-dichloropodophenazine, benzopodophenazine, and their 4β-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors

  Journal of Medicinal Chemistry. 1996;39(7):1396-1402.
  47

• 152.

  1996

  X. Chen; K. Bastow; B. Goz; L. Kucera; S.L. Morris-Natschke; K.S. Ishaq

  Boronic acid derivatives targeting HIV-1

  Antiviral Chemistry and Chemotherapy. 1996;7(2):108-114.
  14

• 153.

  1996

  Xiannong Chen; Kenneth Bastow; Barry Goz; Louis S. Kucera; Susan L. Morris-Natschke; Khalid S. Ishaq

  Synthesis and evaluation of novel thymidine analogs as antitumor and antiviral agents

  Journal of Medicinal Chemistry. 1996;39(17):3412-3417.
  3

• 154.

  1995

  Y. Kashiwada; K.F. Bastow; K.-H. Lee

  Novel lignan derivatives as selective inhibitors of DNA topoisomerase II

  Bioorganic and Medicinal Chemistry Letters. 1995;5(8):905-908.
  18

• 155.

  1995

  Y. Fukushima; K.F. Bastow; T. Ohba; K.H. Lee

  Antiviral activity of dammarane saponins against herpes simplex virus I

  International Journal of Pharmacognosy. 1995;33(1):2-6.
  7

• 156.

  1994

  Kenneth F. Bastow; Masataka Itoigawa; Hiroshi Furukawa; Yoshiki Kashiwada; Ibrahim D. Bori; Lawrence M. Ballas; Kuo-Hsiung Lee

  Antiproliferative actions of 7-substituted 1,3-dihydroxyacridones; possible involvement of DNA topoisomerase II and protein kinase C as biochemical targets

  Bioorganic and Medicinal Chemistry. 1994;2(12):1403-1411.
  17

• 157.

  1994

  A. Sood; B.F. Spielvogel; W.J. Powell; K.F. Bastow; M.C. Miller; I.H. Hall

  Cytotoxicity of ribo - and arabinoside boron nucleosides in tissue culture cells

  Anticancer Research. 1994;14(4 A):1483-1488.
  12

• 158.

  1993

  Yoshiki Kashiwada; Li Sun; Hiroshi Tatematsu; Kenneth F. Bastow; Kuo-Hsiung Lee

  Structures of tetra-O-demethylcolchicine, -isocolchicine, and 10-O-demethylcolchicine derivatives

  Heterocycles. 1993;36(11):2531-2540.
  2

• 159.

  1993

  Kenneth F. Bastow; Hiroshi Tatematsu; Li Sun; Yasuhiro Fukushima; Kuo-Hsiung Lee

  Synthesis and biological evaluation of tetrademethyl isocolchicine derivatives as inhibitors of DNA topoisomerase action in vitro

  Bioorganic and Medicinal Chemistry. 1993;1(3):227-234.
  5

• 160.

  1993

  Y. Kashiwada; G.-I. Nonaka; I. Nishioka; K.J.-H. Lee; I. Bori; Y. Fukushima; K.F. Bastow; K.-H. Lee

  Tannins as potent inhibitors of DNA topoisomerase II in vitro

  Journal of Pharmaceutical Sciences. 1993;82(5):487-492.
  54

• 161.

  1993

  K.F. Bastow; I.D. Bori; Y. Fukushima; Y. Kashiwada; T. Tanaka; G. Nonaka; I. Nishioka; K.-H. Lee

  Inhibition of DNA topoisomerases by sanguiin H-6, a cytotoxic dimeric ellagitannin from Sanguisorba officinalis

  Planta Medica. 1993;59(3):240-245.
  21

• 162.

  1993

  K.F. Bastow; H. Tatematsu; I.D. Bori; Y. Fukushima; L. Sun; B. Goz; K.-H. Lee

  Induction of reversible protein-linked DNA breaks in human osteogenic sarcoma cells by novel cytocidal colchicine derivatives which inhibit DNA topoisomerase II in vitro: Absence of cross-resistance in a colchicine-resistant sub-clone

  Bioorganic and Medicinal Chemistry Letters. 1993;3(6):1045-1050.
  9

• 163.

  1989

  Kenneth F. Bastow; Bing-Sen Zhou; Yung-Chi Cheng

  Human topoisomerase 1 messenger RNA is not destabilized by the herpes simplex virus type 2 virion-associated shut-off function

  Virus Genes. 1989;2(4):357-365.
  0

• 164.

  1989

  B.-S. Zhou; K.F. Bastow; Y.-C. Cheng

  Characterization of the 3' region of the human DNA topoisomerase I gene

  Cancer Research. 1989;49(14):3922-3927.
  4

• 165.

  1988

  J.S. Gibbs; H.C. Chiou; K.F. Bastow; Y.-C. Cheng; D.M. Coen

  Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition

  Proceedings of the National Academy of Sciences of the United States of America. 1988;85(18):6672-6676.
  69

• 166.

  1987

  Y.C. Cheng; G.E. Dutschman; K.F. Bastow; M.G. Sarngadharan; R.Y. Ting

  Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs

  Journal of Biological Chemistry. 1987;262(5):2187-2189.
  76

• 167.

  1986

  K.F. Bastow; J. Bouchard; X.-J. Ren; Y.-C. Cheng

  Synthesis of dihydrofolate reductase and metabolism of related RNA in a methotrexate resistant human cell line infected with herpes simplex virus type 2

  Virology. 1986;149(2):199-207.
  1

• 168.

  1985

  J. Bouchard; K.F. Bastow; M.C. Starnes; R. Prabhu; Y.C. Cheng

  Characterization of dihydrofolate reductase-related DNA and RNA from human KB cell subclones containing different amounts of enzyme

  Cancer Research. 1985;45(4):1717-1722.
  1

• 169.

  1984

  K.F. Bastow; R. Prabhu; Y-C. Cheng

  The intracellular content of dihydrofolate reductase: possibilities for control and implications for chemotherapy

  Advances in Enzyme Regulation. 1984;22(C):15-26.
  14

• 170.

  1984

  K.B. Frank; D.D. Derse; K.F. Bastow; Y.C. Cheng

  Novel interaction of aphidicolin with herpes simplex virus DNA polymerase and polymerase-associated exonuclease

  Journal of Biological Chemistry. 1984;259(21):13282-13286.
  4

• 171.

  1983

  K.F. Bastow; D.D. Derse; Y.C. Cheng

  Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin

  Antimicrobial Agents and Chemotherapy. 1983;23(6):914-917.
  11

• 172.

  1983

  Y.C. Cheng; S.P. Grill; G.E. Dutschman; K. Nakayama; K.F. Bastow

  Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells

  Journal of Biological Chemistry. 1983;258(20):12460-12464.
  91

• 173.

  1982

  B.A. Domin; K.F. Bastow; S.P. Grill; Yung-Chi Cheng

  Methotrexate resistant human KB cells: Size heterogeneity of dihydrofolate reductase related RNAs and effect of methotrexate on dihydrofolate reductase activity

  Federation Proceedings. 1982;41(4):No. 4572.
  0

• 174.

  1982

  B.A. Domin; S.P. Grill; K.F. Bastow; Y.C. Cheng

  Effects of methotrexate on dihydrofolate reductase activity in methotrexate-resistant human KB cells

  Molecular Pharmacology. 1982;21(2):478-482.
  17

• 175.

  1982

  A. Minson; S.E. Bell; K. Bastow

  Correlation of the virus sequence content and biological properties of cells carrying the herpes simplex virus type 2 thymidine kinase gene

  Journal of General Virology. 1982;58(1):127-138.
  0

• 176.

  1982

  D. Derse; K.F. Bastow; Y. Cheng

  Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid

  Journal of Biological Chemistry. 1982;257(17):10251-10260.
  15

• 177.

  1980

  K.F. Bastow; G. Darby; P. Wildy; A.C. Minson

  Properties of cells carrying the herpes simplex virus type 2 thymidine kinase gene: Mechanisms of reversion to a thymidine kinase-negative phenotype

  Journal of Virology. 1980;36(3):746-755.
  0

• 178.

  1980

  G. Darby; B.A. Larder; K.F. Bastow; H.J. Field

  Sensitivity of viruses to phosphorylated 9-(2-hydroxyethoxymethyl)guanine revealed in TK-transformed cells

  Journal of General Virology. 1980;48(2):451-454.
  5