Nigel Mackman

UNCCH, School of Medicine, Medicine

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Nigel Mackman

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Medicine
  
  

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Nigel MacKman

  Uremic serum and ubiquitylation of tissue factor

  Circulation. 2013;127(3):320-321.
  0

• 2.

  2013

  Linda Kidd; Nigel Mackman

  Prothrombotic mechanisms and anticoagulant therapy in dogs with immune-mediated hemolytic anemia

  Journal of Veterinary Emergency and Critical Care. 2013;23(1):3-13.
  0

• 3.

  2013

  Pierre-Emmanuel Rautou; Nigel Mackman

  Microvesicles as risk markers for venous thrombosis

  Expert Review of Hematology. 2013;6(1):91-101.
  1

• 4.

  2013

  Yacine Boulaftali; Paul R. Hess; Todd M. Getz; Agnieszka Cholka; Moritz Stolla; Nigel Mackman; A. Phillip Owens III; Jerry Ware; Mark L. Kahn; Wolfgang Bergmeier

  Platelet ITAM signaling is critical for vascular integrity in infammation

  Journal of Clinical Investigation. 2013;123(2):908-916.
  2

• 5.

  2013

  Johannes Thaler; Cihan Ay; Nigel Mackman; Sylvia Metz-Schimmerl; Judith Stift; Alexandra Kaider; Leonhard Müllauer; Michael Gnant; Werner Scheithauer; Ingrid Pabinger

  Microparticle-associated tissue factor activity in patients with pancreatic cancer: Correlation with clinicopathological features

  European Journal of Clinical Investigation. 2013;43(3):277-285.
  0

• 6.

  2013

  Silvio Antoniak; A. Phillip Owens III; Martin Baunacke; Julie C. Williams; Rebecca D. Lee; Alice Weithäuser; Patricia A. Sheridan; Ronny Malz; James P. Luyendyk; Denise A. Esserman; et al.

  PAR-1 contributes to the innate immune response during viral infection

  Journal of Clinical Investigation. 2013;123(3):1310-1322.
  0

• 7.

  2013

  Deyan Luo; Jr-Shiuan Lin; Michelle A. Parent; Isis Mullarky-Kanevsky; Frank M. Szaba; Lawrence W. Kummer; Debra K. Duso; Michael Tighe; Jim Hill; Andras Gruber; et al.

  Fibrin facilitates both innate and T cell-mediated defense against Yersinia pestis

  Journal of Immunology. 2013;190(8):4149-4161.
  0

• 8.

  2013

  Bradley P. Sullivan; Anna K. Kopec; Nikita Joshi; Holly Cline; Juliette A. Brown; Stephanie C. Bishop; Karen M. Kassel; Cheryl Rockwell; Nigel Mackman; James P. Luyendyk

  Hepatocyte tissue factor activates the coagulation cascade in mice

  Blood. 2013;121(10):1868-1874.
  0

• 9.

  2012

  R.D. Lee; D.A. Barcel; J.C. Williams; J.G. Wang; J.C. Boles; D.A. Manly; N.S. Key; N. MacKman

  Pre-analytical and analytical variables affecting the measurement of plasma-derived microparticle tissue factor activity

  Thrombosis Research. 2012;129(1):80-85.
  8

• 10.

  2012

  Jeremiah C. Boles; Julie C. Williams; Rachel M. Hollingsworth; Jian-Guo Wang; Sam L. Glover; A. Phillip Owens III; David A. Barcel; Raj S. Kasthuri; Nigel S. Key; Nigel MacKman

  Anthracycline treatment of the human monocytic leukemia cell line THP-1 increases phosphatidylserine exposure and tissue factor activity

  Thrombosis Research. 2012;129(2):197-203.
  2

• 11.

  2012

  Nigel MacKman

  Mouse models, risk factors, and treatments of venous thrombosis

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2012;32(3):554-555.
  0

• 12.

  2012

  Jose A. Diaz; Andrea T. Obi; Daniel D. Myers Jr.; Shirley K. Wrobleski; Peter K. Henke; Nigel MacKman; Thomas W. Wakefield

  Critical review of mouse models of venous thrombosis

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2012;32(3):556-562.
  5

• 13.

  2012

  Pierre-Emmanuel Rautou; Nigel MacKman

  Del-etion of microvesicles from the circulation

  Circulation. 2012;125(13):1601-1604.
  1

• 14.

  2012

  U. Boltzen; A. Eisenreich; S. Antoniak; A. Weithaeuser; H. Fechner; W. Poller; H.P. Schultheiss; N. Mackman; U. Rauch

  Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis

  Journal of Molecular and Cellular Cardiology. 2012;52(5):1056-1065.
  3

• 15.

  2012

  A. Phillip Owens III; Nigel MacKman

  Sources of tissue factor that contribute to thrombosis after rupture of an atherosclerotic plaque

  Thrombosis Research. 2012;129(SUPPL. 2):S30-S33.
  2

• 16.

  2012

  Julie C. Williams; Nigel Mackman

  Tissue factor in health and disease

  Frontiers in Bioscience. 2012;E4(1):358-372.
  2

• 17.

  2012

  Marie-Luise von Brühl; Konstantin Stark; Alexander Steinhart; Sue Chandraratne; Ildiko Konrad; Michael Lorenz; Alexander Khandoga; Anca Tirniceriu; Raffaele Coletti; Maria Köllnberger; et al.

  Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

  Journal of Experimental Medicine. 2012;209(4):819-835.
  30

• 18.

  2012

  Raj S. Kasthuri; Sam L. Glover; William Jonas; Troy McEachron; Rafal Pawlinski; Gowthami M. Arepally; Nigel S. Key; Nigel Mackman

  PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI

  Blood. 2012;119(22):5285-5293.
  4

• 19.

  2012

  Jian-Guo Wang; Julia E. Geddings; Maria M. Aleman; Jessica C. Cardenas; Pichika Chantrathammachart; Julie C. Williams; Daniel Kirchhofer; Vladimir Y. Bogdanov; Ronald R. Bach; Janusz Rak; et al.

  Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

  Blood. 2012;119(23):5543-5552.
  5

• 20.

  2012

  Fabrice Jaffré; Alan E. Friedman; Zhaoyang Hu; Nigel MacKman; Burns C. Blaxall

  β-Adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells

  Circulation. 2012;125(24):2993-3003.
  3

• 21.

  2012

  A. Phillip Owens III; Freda H. Passam; Silvio Antoniak; Stephanie M. Marshall; Allison L. McDaniel; Lawrence Rudel; Julie C. Williams; Brian K. Hubbard; Julie-Ann Dutton; Jianguo Wang; et al.

  Monocyte tissue factor - Dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

  Journal of Clinical Investigation. 2012;122(2):558-568.
  12

• 22.

  2012

  J. Thaler; C. Ay; N. Mackman; R.M. Bertina; A. Kaider; C. Marosi; N.S. Key; D.A. Barcel; W. Scheithauer; G. Kornek; et al.

  Microparticle-associated tissue factor activity, venous thromboembolism and mortality in pancreatic, gastric, colorectal and brain cancer patients

  Journal of Thrombosis and Haemostasis. 2012;10(7):1363-1370.
  5

• 23.

  2012

  Nigel Mackman

  New insights into the mechanisms of venous thrombosis

  Journal of Clinical Investigation. 2012;122(7):2331-2336.
  2

• 24.

  2012

  Frederiek F. van Doormaal; Ankie Kleinjan; René J. Berckmans; Nigel Mackman; David Manly; Pieter W. Kamphuisen; Dick J. Richel; Harry R. Büller; Auguste Sturk; Rienk Nieuwland

  Coagulation activation and microparticle-associated coagulant activity in cancer patients: An exploratory prospective study

  Thrombosis and Haemostasis. 2012;108(1):160-165.
  3

• 25.

  2012

  Pichika Chantrathammachart; Nigel Mackman; Erica Sparkenbaugh; Jian-Guo Wang; Leslie V. Parise; Daniel Kirchhofer; Nigel S. Key; Rafal Pawlinski

  Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease

  Blood. 2012;120(3):636-646.
  1

• 26.

  2012

  Ilene C. Weitz; Pedram Razavi; Leanne Rochanda; Jeffrey Zwicker; Bruce Furie; David Manly; Nigel MacKman; Ralph Green; Howard A. Liebman

  Eculizumab therapy results in rapid and sustained decreases in markers of thrombin generation and inflammation in patients with PNH independent of its effects on hemolysis and microparticle formation

  Thrombosis Research. 2012;130(3):361-368.
  3

• 27.

  2012

  M.R. Cronan; K. Nakamura; N.L. Johnson; D.A. Granger; B.D. Cuevas; J.-G. Wang; N. MacKman; J.E. Scott; H.G. Dohlman; G.L. Johnson

  Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis

  Oncogene. 2012;31(34):3889-3900.
  1

• 28.

  2012

  R. Lee; J.C. Williams; N. Mackman

  P2X7 regulation of macrophage tissue factor activity and microparticle generation

  Journal of Thrombosis and Haemostasis. 2012;10(9):1965-1967.
  0

• 29.

  2012

  Rita Marchi; Bethany L. Walton; Colleen S. McGary; Feng-Chang Lin; Alice D. Ma; Rafal Pawlinski; Nigel MacKman; Robert A. Campbell; Jorge Di Paola; Alisa S. Wolberg

  Dysregulated coagulation associated with hypofibrinogenaemia and plasma hypercoagulability: Implications for identifying coagulopathic mechanisms in humans

  Thrombosis and Haemostasis. 2012;108(3):516-526.
  0

• 30.

  2012

  Nigel Mackman

  New insights into the mechanisms of venous thrombosis (Journal of Clinical Investigation (2012) 122, 7 (2331-2336) DOI: 10.1172/JCI60229)

  Journal of Clinical Investigation. 2012;122(9):3368.
  0

• 31.

  2012

  Roxane Darbousset; Grace M. Thomas; Soraya Mezouar; Corinne Frère; Rénaté Bonier; Nigel Mackman; Thomas Renné; Françoise Dignat-George; Christophe Dubois; Laurence Panicot-Dubois

  Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation

  Blood. 2012;120(10):2133-2143.
  6

• 32.

  2012

  Anna L. Hampton; Jose A. Diaz; Angela E. Hawley; Shirley K. Wrobleski; Jian-Guo Wang; Rebecca D. Lee; Daniel Kirchhofer; Robert E. Sigler; Thomas W. Wakefield; Nigel MacKman; et al.

  Myeloid cell tissue factor does not contribute to venous thrombogenesis in an electrolytic injury model

  Thrombosis Research. 2012;130(4):640-645.
  0

• 33.

  2012

  Nobuyuki Takahashi; Feng Li; Chi-Hong Wang; Nigel Mackman; Nobuyo Maeda; Oliver Smithies; J. Charles Jennette

  Decreased eNOS and high fat diet in diabetic nephropathy

  Therapeutic Research. 2012;33(8):1206-1208.
  0

• 34.

  2012

  Julie A. Bastarache; Sara C. Sebag; Jennifer K. Clune; Brandon S. Grove; William E. Lawson; David R. Janz; L. Jackson Roberts II; Ryszard Dworski; Nigel Mackman; Lorraine B. Ware

  Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress

  Thorax. 2012;67(12):1032-1039.
  0

• 35.

  2012

  A. Phillip Owens III; Nigel MacKman

  Role of tissue factor in atherothrombosis

  Current Atherosclerosis Reports. 2012;14(5):394-401.
  0

• 36.

  2011

  Silvio Antoniak; Rafal Pawlinski; Nigel Mackman

  Protease-activated receptors and myocardial infarction

  IUBMB Life. 2011;63(6):383-389.
  6

• 37.

  2011

  Deyan Luo; Frank M. Szaba; Lawrence W. Kummer; Edward F. Plow; Nigel Mackman; David Gailani; Stephen T. Smiley

  Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica

  Journal of Immunology. 2011;187(4):1866-1876.
  7

• 38.

  2011

  Jian-Guo Wang; Julie C. Williams; Beckley K. Davis; Ken Jacobson; Claire M. Doerschuk; Jenny P.-Y. Ting; Nigel Mackman

  Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner

  Blood. 2011;118(8):2366-2374.
  16

• 39.

  2011

  A.P. Owens Iii; Y. Lu; H.C. Whinna; C. Gachet; W.P. Fay; N. Mackman

  Towards a standardization of the murine ferric chloride-induced carotid arterial thrombosis model

  Journal of Thrombosis and Haemostasis. 2011;9(9):1862-1863.
  2

• 40.

  2011

  Troy A. McEachron; Frank C. Church; Nigel MacKman

  Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells

  Blood Coagulation and Fibrinolysis. 2011;22(7):576-582.
  1

• 41.

  2011

  Yuan Liu; Pengfei Jiang; Katerina Capkova; Dong Xue; Longwu Ye; Subhash C. Sinha; Nigel Mackman; Kim D. Janda; Cheng Liu

  Tissue factor-activated coagulation cascade in the tumor microenvironment is critical for tumor progression and an effective target for therapy

  Cancer Research. 2011;71(20):6492-6502.
  11

• 42.

  2011

  Karen M. Kassel; A. Phillip Owens III; Cheryl E. Rockwell; Bradley P. Sullivan; Ruipeng Wang; Ossama Tawfik; Guodong Li; Grace L. Guo; Nigel MacKman; James P. Luyendyk

  Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet

  American Journal of Pathology. 2011;179(5):2278-2289.
  3

• 43.

  2011

  Alain Tedgui; A. Phillip Owens; Nigel MacKman

  2011 nobel prize in physiology or medicine: Toll-like receptors, dendritic cells, and their roles in atherosclerosis

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2011;31(12):2767-2768.
  4

• 44.

  2011

  A. Phillip Owens III; Nigel MacKman

  MP's and VTE's: Fact or fiction

  Thrombosis Research. 2011;128(6):505-506.
  0

• 45.

  2011

  Julia E. Gambon; A. Phillip Owens III; Nigel Mackman

  Comment on "tissue factor-dependent chemokine production aggravates experimental colitis"

  Molecular Medicine. 2011;17(11):1131.
  1

• 46.

  2011

  Nigel MacKman; George E. Davis

  Blood coagulation and blood vessel development: Is tissue factor the missing link?

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2011;31(11):2364-2366.
  1

• 47.

  2011

  James P. Luyendyk; Nigel Mackman; Bradley P. Sullivan

  Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury

  Toxicological Sciences. 2011;119(1):233-243.
  4

• 48.

  2011

  Mohit Bhandari; Frederick A. Ofosu; Nigel MacKman; Craig Jackson; Cataldo Doria; John E. Humphries; Sateesh C. Babu; Thomas L. Ortel; David Hoffman Van Thiel; Jeanine M. Walenga; et al.

  Safety and efficacy of thrombin-JMI: A multidisciplinary expert group consensus

  Clinical and Applied Thrombosis/Hemostasis. 2011;17(1):39-45.
  1

• 49.

  2011

  James P. Luyendyk; Kevin C. Flanagan; C. David Williams; Hartmut Jaeschke; Joyce G. Slusser; Nigel Mackman; Glenn H. Cantor

  Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice

  Toxicology and Applied Pharmacology. 2011;250(3):256-262.
  1

• 50.

  2011

  Julie C. Williams; Nigel Mackman

  MPs or ICs?

  Blood. 2011;117(4):1101-1102.
  5

• 51.

  2011

  David A. Manly; Jeremiah Boles; Nigel MacKman

  Role of tissue factor in venous thrombosis

  Annual Review of Physiology. 2011;73:515-525.
  15

• 52.

  2011

  M.T. Rondina; H. Schwertz; E.S. Harris; B.F. Kraemer; R.A. Campbell; N. Mackman; C.K. Grissom; A.S. Weyrich; G.A. Zimmerman

  The septic milieu triggers expression of spliced tissue factor mRNA in human platelets

  Journal of Thrombosis and Haemostasis. 2011;9(4):748-758.
  10

• 53.

  2011

  A. Phillip Owens; Nigel MacKman

  Microparticles in hemostasis and thrombosis

  Circulation Research. 2011;108(10):1284-1297.
  70

• 54.

  2010

  E.O. Jenkins; D. Schiff; N. Mackman; N.S. Key

  Venous thromboembolism in malignant gliomas

  Journal of Thrombosis and Haemostasis. 2010;8(2):221-227.
  17

• 55.

  2010

  Veronique Ollivier; Jianguo Wang; David Manly; Kellie R. Machlus; Alisa S. Wolberg; Martine Jandrot-Perrus; Nigel Mackman

  Detection of endogenous tissue factor levels in plasma using the calibrated automated thrombogram assay

  Thrombosis Research. 2010;125(1):90-96.
  18

• 56.

  2010

  Nigel MacKman; Richard C. Becker

  DVT: A new era in anticoagulant therapy

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2010;30(3):369-371.
  8

• 57.

  2010

  Mutsumi Nagai; Cigdem Erkuran Yilmaz; Daniel Kirchhofer; Charles T. Esmon; Nigel MacKman; D. Neil Granger

  Role of coagulation factors in cerebral venous sinus and cerebral microvascular thrombosis

  Neurosurgery. 2010;66(3):560-565.
  5

• 58.

  2010

  Rafal Pawlinski; Nigel Mackman

  Cellular sources of tissue factor in endotoxemia and sepsis

  Thrombosis Research. 2010;125(SUPPL. 1):S70-S73.
  23

• 59.

  2010

  Dougald M. Monroe; Nigel Mackman; Maureane Hoffman

  Wound healing in hemophilia B mice and low tissue factor mice

  Thrombosis Research. 2010;125(SUPPL. 1):S74-S77.
  5

• 60.

  2010

  L. Vijaya Mohan Rao; Nigel Mackman

  Factor VIIa and tissue factor - from cell biology to animal models

  Thrombosis Research. 2010;125(SUPPL. 1):S1-S3.
  4

• 61.

  2010

  J. Boles; N. MacKman

  Role of tissue factor in thrombosis in antiphospholipid antibody syndrome

  Lupus. 2010;19(4):370-378.
  12

• 62.

  2010

  David A. Manly; Jianguo Wang; Sam L. Glover; Raj Kasthuri; Howard A. Liebman; Nigel S. Key; Nigel Mackman

  Increased microparticle tissue factor activity in cancer patients with Venous Thromboembolism

  Thrombosis Research. 2010;125(6):511-512.
  46

• 63.

  2010

  Noppacharn Uaprasert; Peter M. Voorhees; Nigel Mackman; Nigel S. Key

  Venous thromboembolism in multiple myeloma: Current perspectives in pathogenesis

  European Journal of Cancer. 2010;46(10):1790-1799.
  12

• 64.

  2010

  N. Mackman; A. Gruber

  Platelet polyphosphate: An endogenous activator of coagulation factor XII

  Journal of Thrombosis and Haemostasis. 2010;8(5):865-867.
  6

• 65.

  2010

  Rafal Pawlinski; Jian-Guo Wang; A. Phillip Owens III; Julie Williams; Silvio Antoniak; Michael Tencati; Thomas Luther; Jesse W. Rowley; Elizabeth N. Low; Andrew S. Weyrich; et al.

  Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice

  Blood. 2010;116(5):806-814.
  39

• 66.

  2010

  Nigel Mackman

  Balancing clotting

  Blood. 2010;116(10):1634-1635.
  0

• 67.

  2010

  A. Phillip Owens III; Nigel Mackman

  Tissue factor and thrombosis: The clot starts here

  Thrombosis and Haemostasis. 2010;104(3):432-439.
  29

• 68.

  2010

  Raj S. Kasthuri; Sam L. Glover; Jeremiah Boles; Nigel MacKman

  Tissue factor and tissue factor pathway inhibitor as key regulators of global hemostasis: Measurement of their levels in coagulation assays

  Seminars in Thrombosis and Hemostasis. 2010;36(7):764-771.
  8

• 69.

  2010

  Silvio Antoniak; Mauricio Rojas; Denise Spring; Tara A. Bullard; Edward D. Verrier; Burns C. Blaxall; Nigel MacKman; Rafal Pawlinski

  Protease-activated receptor 2 deficiency reduces cardiac ischemia/reperfusion injury

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2010;30(11):2136-2142.
  11

• 70.

  2010

  F. Li; C.-H. Wang; J.-G. Wang; T. Thai; G. Boysen; L. Xu; A.L. Turner; A.S. Wolberg; N. Mackman; N. Maeda; et al.

  Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet

  Journal of Thrombosis and Haemostasis. 2010;8(10):2122-2132.
  2

• 71.

  2010

  Troy A. McEachron; Rafal Pawlinski; Kristy L. Richards; Frank C. Church; Nigel Mackman

  Protease-activated receptors mediate crosstalk between coagulation and fibrinolysis

  Blood. 2010;116(23):5037-5044.
  12

• 72.

  2010

  Nigel S. Key; Nigel MacKman

  Tissue factor and its measurement in whole blood, plasma, and microparticles

  Seminars in Thrombosis and Hemostasis. 2010;36(8):865-875.
  14

• 73.

  2009

  Keon E. Menzies; Nigel MacKman; Mark B. Taubman

  Role of tissue factor in cancer

  Cancer Investigation. 2009;27(SUPPL. 1):53-62.
  1

• 74.

  2009

  Som D. Mukherjee; Laura L. Swystun; Nigel Mackman; Jian-Guo Wang; Gregory Pond; Mark N. Levine; Patricia C. Liaw

  Impact of chemotherapy on thrombin generation and on the protein C pathway in breast cancer patients

  Pathophysiology of Haemostasis and Thrombosis. 2009;37(2-4):88-97.
  6

• 75.

  2009

  R. Pawlinski; Nigel Mackman

  Tissue factor and heart inflammation

  Journal of Thrombosis and Haemostasis. 2009;7(2):288-289.
  2

• 76.

  2009

  Robert Flaumenhaft; William C. Aird; Beth A. Bouchard; Tatiana V. Byzova; Kevin Croce; Jonathon M. Gibbins; Peter L. Gross; John A. Heit; Joseph E. Italiano; Howard Liebman; et al.

  Preface

  Journal of Thrombosis and Haemostasis. 2009;7(SUPPL. 1):v.
  0

• 77.

  2009

  Nigel Mackman

  The many faces of tissue factor

  Journal of Thrombosis and Haemostasis. 2009;7(SUPPL. 1):136-139.
  58

• 78.

  2009

  Carl F. Raetzsch; Natasha L. Brooks; J. McKee Alderman; Kelli S. Moore; Peter A. Hosick; Simon Klebanov; Shizuo Akira; James E. Bear; Albert S. Baldwin; et al.

  Lipopolysaccharide inhibition of glucose production through the toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor κB pathway

  Hepatology. 2009;50(2):592-600.
  17

• 79.

  2009

  Surya V. Seshan; Claus-Werner Franzke; Patricia Redecha; Marc Monestier; Nigel Mackman; Guillermina Girardi

  Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies

  Blood. 2009;114(8):1675-1683.
  20

• 80.

  2009

  Raj S. Kasthuri; Mark B. Taubman; Nigel Mackman

  Role of tissue factor in cancer

  Journal of Clinical Oncology. 2009;27(29):4834-4838.
  82

• 81.

  2009

  T. Mceachron; N. Mackman

  Tumors, ticks and tissue factor

  Journal of Thrombosis and Haemostasis. 2009;7(11):1852-1854.
  2

• 82.

  2009

  Nigel MacKman; Mark Taubman

  Tissue factor: Past, present, and future

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2009;29(12):1986-1988.
  12

• 83.

  2009

  Alisa S. Wolberg; Nigel Mackman

  Venous thromboembolism risk factors, biomarkers, and treatment

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2009;29(3):296-297.
  0

• 84.

  2009

  Nigel Mackman; Susan Smyth

  Cardiovascular disease in women

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2009;29(3):277-278.
  3

• 85.

  2009

  Nigel Mackman

  Bleeding hearts

  Blood. 2009;113(3):500-501.
  0

• 86.

  2009

  Yi-Dan Li; Bu-Qing Ye; Sheng-Xi Zheng; Jin-Tao Wang; Jian-Guo Wang; Ming Chen; Ji-Guo Liu; Xin-Hui Pei; Li-Jing Wang; Zhi-Lin Lin; et al.

  NF-κB transcription factor p50 critically regulates tissue factor in deep vein thrombosis

  Journal of Biological Chemistry. 2009;284(7):4473-4483.
  19

• 87.

  2009

  Nigel MacKman

  The role of tissue factor and factor VIIa in hemostasis

  Anesthesia and Analgesia. 2009;108(5):1447-1452.
  38

• 88.

  2009

  Nigel Mackman

  On the trail of microparticles

  Circulation Research. 2009;104(8):925-927.
  14

• 89.

  2009

  James P. Luyendyk; Glenn H. Cantor; Daniel Kirchhofer; Nigel Mackman; Bryan L. Copple; Ruipeng Wang

  Tissue factor-dependent coagulation contributes to α- naphthylisothiocyanate-induced cholestatic liver injury in mice

  American Journal of Physiology - Gastrointestinal and Liver Physiology. 2009;296(4):G840-G849.
  12

• 90.

  2009

  Alyson K. Baker; Ruipeng Wang; Nigel Mackman; James P. Luyendyk

  Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-α expression in macrophages by reducing IL-10 expression

  Molecular Immunology. 2009;46(11-12):2249-2255.
  9

• 91.

  2009

  J.-G. Wang; D. Manly; D. Kirchhofer; R. Pawlinski; Nigel Mackman

  Levels of microparticle tissue factor activity correlate with coagulation activation in endotoxemic mice

  Journal of Thrombosis and Haemostasis. 2009;7(7):1092-1098.
  38

• 92.

  2009

  Guillermina Girardi; Nigel Mackman

  Chapter 5 Tissue Factor in Antiphospholipid Antibody-induced Pregnancy Loss: Thrombosis versus Inflammation

  Handbook of Systemic Autoimmune Diseases. 2009;10:69-79.
  0

• 93.

  2009

  Li Wang; Christine Miller; Robert F. Swarthout; Mohan Rao; Nigel Mackman; Mark B. Taubman

  Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury

  Blood. 2009;113(3):705-713.
  43

• 94.

  2008

  Chirag Amin; Nigel MacKman; Nigel S. Key

  Microparticles and cancer

  Pathophysiology of Haemostasis and Thrombosis. 2008;36(3-4):177-183.
  15

• 95.

  2008

  Rafal Pawlinski; Michael Tencati; Craig R. Hampton; Denise Spring; Timothy H. Pohlman; Edward D. Verrier; Tetsuro Shishido; Tara A. Bullard; Liam M. Casey; Jun-Ichi Abe; et al.

  Response to letter regarding article, "protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy"

  Circulation. 2008;117(24):e496.
  1

• 96.

  2008

  Nifel Mackman

  Tissue-specific hemostasis: Role of tissue factor

  Journal of Thrombosis and Haemostasis. 2008;6(2):303-305.
  13

• 97.

  2008

  Nigel Mackman

  Triggers, targets and treatments for thrombosis

  Nature. 2008;451(7181):914-918.
  164

• 98.

  2008

  Christoph Reinhardt; Marie-Luise Von Brühl; Davit Manukyan; Lenka Grahl; Michael Lorenz; Berid Altmann; Silke Dlugai; Sonja Hess; Ildiko Konrad; Lena Orschiedt; et al.

  Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation

  Journal of Clinical Investigation. 2008;118(3):1110-1122.
  98

• 99.

  2008

  Stephan Moll; Nigel Mackman

  Venous thromboembolism: A need for more public awareness and research into mechanisms

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2008;28(3):367-369.
  13

• 100.

  2008

  Gernot Schabbauer; James Luyendyk; Karine Crozat; Zhengfan Jiang; Nigel Mackman; Siamak Bahram; Philippe Georgel

  TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages

  Molecular Immunology. 2008;45(10):2790-2796.
  15

• 101.

  2008

  Gourab Bhattacharjee; Jasimuddin Ahamed; Rafal Pawlinski; Cheng Liu; Nigel MacKman; Wolfram Ruf; Thomas S. Edgington

  Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1

  Circulation Research. 2008;102(4):457-464.
  16

• 102.

  2008

  Nigel Mackman; Mark B. Taubman

  Does tissue factor expression by vascular smooth muscle cells provide a link between C-reactive protein and cardiovascular disease?

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2008;28(4):601-603.
  2

• 103.

  2008

  Rachel E. Tilley; Todd Holscher; Rajesh Belani; Jorge Nieva; Nigel Mackman

  Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients

  Thrombosis Research. 2008;122(5):604-609.
  36

• 104.

  2008

  James P. Luyendyk; Gernot A. Schabbauer; Michael Tencati; Todd Holscher; Rafal Pawlinski; Nigel Mackman

  Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages

  Journal of Immunology. 2008;180(6):4218-4226.
  60

• 105.

  2008

  Elke Hoffmann; Judith Ashouri; Sabine Wolter; Anneke Doerrie; Oliver Dittrich-Breiholz; Heike Schneider; Erwin F. Wagner; Jakob Troppmair; Nigel Mackman; Michael Kracht

  Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway

  Journal of Biological Chemistry. 2008;283(18):12120-12128.
  28

• 106.

  2008

  Linda B. Kidd; Gernot A. Schabbauer; James P. Luyendyk; Todd D. Holscher; Rachel E. Tilley; Michael Tencati; Nigel Mackman

  Insulin activation of the phosphatidylinositol 3-kinase/protein kinase B (Akt) pathway reduces lipopolysaccharide-induced inflammation in mice

  Journal of Pharmacology and Experimental Therapeutics. 2008;326(1):348-353.
  23

• 107.

  2008

  James Morrissey; Nigel Mackman

  Tissue factor and factor VIIa: Understanding the molecular mechanism

  Thrombosis Research. 2008;122(SUPPL.1):S1-S2.
  1

• 108.

  2008

  Rafal Pawlinski; Nigel Mackman

  Use of mouse models to study the role of tissue factor in tumor biology

  Seminars in Thrombosis and Hemostasis. 2008;34(2):182-186.
  6

• 109.

  2008

  Alok A. Khorana; C.W. Francis; K.E. Menzies; J.-G. Wang; O. Hyrien; J. Hathcock; N. Mackman; M.B. Taubman

  Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer

  Journal of Thrombosis and Haemostasis. 2008;6(11):1983-1985.
  78

• 110.

  2008

  Joanne Yu; Linda May; Chloe Milsom; G. Mark Anderson; Jeffrey I. Weitz; James P. Luyendyk; George Broze; Nigel Mackman; Janusz Rak

  Contribution of host-derived tissue factor to tumor neovascularization

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2008;28(11):1975-1981.
  29

• 111.

  2008

  Patricia Redecha; Claus-Werner Franzke; Wolfram Ruf; Nigel Mackman; Guillermina Girardi

  Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome

  Journal of Clinical Investigation. 2008;118(10):3453-3461.
  73

• 112.

  2008

  Guillermina Girardi; N. Mackman

  Tissue factor in antiphospholipid antibody-induced pregnancy loss: A pro-inflammatory molecule

  Lupus. 2008;17(10):931-936.
  11

• 113.

  2008

  Chloe C. Milsom; Joanne L. Yu; Nigel Mackman; Johann Micallef; G. Mark Anderson; Abhijit Guha; Janusz W. Rak

  Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: Effect on tumor initiation and angiogenesis

  Cancer Research. 2008;68(24):10068-10076.
  38

• 114.

  2007

  Nigel Mackman

  Alternatively spliced tissue factor - One cut too many?

  Thrombosis and Haemostasis. 2007;97(1):5-8.
  21

• 115.

  2007

  Darren R. Davis; Kate Wilson; Melissa J. Sam; Sean E. Kennedy; Nigel Mackman; John A. Charlesworth; Jonathan H. Erlich

  The development of cardiac fibrosis in low tissue factor mice is gender-dependent and is associated with differential regulation of urokinase plasminogen activator

  Journal of Molecular and Cellular Cardiology. 2007;42(3):559-571.
  10

• 116.

  2007

  Alana A. Shigeoka; Todd D. Holscher; Andrew J. King; Frank W. Hall; William B. Kiosses; Peter S. Tobias; Nigel Mackman; Dianne B. McKay

  TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both myD88-dependent and -independent pathways

  Journal of Immunology. 2007;178(10):6252-6258.
  119

• 117.

  2007

  Andrew S. Weyrich; Hansjörg Schwertz; Nigel Mackman

  Platelet tissue factor comes of age

  Blood. 2007;109(12):5069-5070.
  4

• 118.

  2007

  R. Pawlinski; M. Tencati; T. Holscher; B. Pedersen; T. Voet; R.E. Tilley; P. Marynen; Nigel Mackman

  Role of cardiac myocyte tissue factor in heart hemostasis

  Journal of Thrombosis and Haemostasis. 2007;5(8):1693-1700.
  36

• 119.

  2007

  James P. Luyendyk; J Daniel Piper; Michael Tencati; K. Veera Reddy; Todd Holscher; Rong Zhang; Jayraz Luchoomun; Xilin Chen; Wang Min; Charles Kunsch; et al.

  A novel class of antioxidants inhibit LPS induction of tissue factor by selective inhibition of the activation of ASK1 and MAP kinases

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2007;27(8):1857-1863.
  19

• 120.

  2007

  Nigel Mackman; Rachel E. Tilley; Nigel S. Key

  Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2007;27(8):1687-1693.
  157

• 121.

  2007

  Mallika Ghosh; Haibin Wang; Youxi Ai; Elisa Romeo; James P. Luyendyk; Jeffrey M. Peters; Nigel Mackman; Sudhansu K. Dey; Timothy Hla

  COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARδ activation

  Journal of Experimental Medicine. 2007;204(9):2053-2061.
  33

• 122.

  2007

  Edward J. Kerschen; José A. Fernandez; Brian C. Cooley; Xia V. Yang; Rashmi Sood; Laurent O. Mosnier; Francis J. Castellino; Nigel Mackman; John H. Griffin; Hartmut Weiler

  Endotoxemia and sepsis mortality reduction by non-anticoagulant-activated protein C

  Journal of Experimental Medicine. 2007;204(10):2439-2448.
  146

• 123.

  2007

  Patricia Redecha; Rachel Tilley; Michael Tencati; Jane E. Salmon; Daniel Kirchhofer; Nigel Mackman; Guillermina Girardi

  Tissue factor: A link between C5a and neutrophil activation in antiphospholipid antibody-induced fetal injury

  Blood. 2007;110(7):2423-2431.
  103

• 124.

  2007

  Rafal Pawlinski; Michael Tencati; Craig R. Hampton; Tetsuro Shishido; Tara A. Bullard; Liam M. Casey; Patricia Andrade-Gordon; Matthias Kotzsch; Denise Spring; et al.

  Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy

  Circulation. 2007;116(20):2298-2306.
  27

• 125.

  2007

  Chloe Milsom; Joanne Yu; Linda May; Brian Meehan; Nathalie Magnus; Khalid Al-Nedawi; Jim Luyendyk; Jefferey Weitz; Petr Klement; George Broze; et al.

  The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression

  Thrombosis Research. 2007;120(SUPPL. 2):S82-S91.
  15

• 126.

  2007

  Patricia E. Ganey; James P. Luyendyk; Sandra W. Newport; Theresa M. Eagle; Jane F. Maddox; Nigel Mackman; Robert A. Roth

  Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice

  Hepatology. 2007;46(4):1177-1186.
  35

• 127.

  2007

  Jacob Sevastos; Sean E. Kennedy; Darren R. Davis; Melissa Sam; Philip W. Peake; John A. Charlesworth; Nigel Mackman; Jonathan H. Erlich

  Tissue factor deficiency and PAR-1 deficiency are protective against renal ischemia reperfusion injury

  Blood. 2007;109(2):577-583.
  39

• 128.

  2006

  Hansjörg Schwertz; Neal D. Tolley; Jason M. Foulks; Melvin M. Denis; Ben W. Risenmay; Michael Buerke; Rachel E. Tilley; Matthew T. Rondina; Estelle M. Harris; Larry W. Kraiss; et al.

  Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets

  Journal of Experimental Medicine. 2006;203(11):2433-2440.
  134

• 129.

  2006

  Janusz Rak; Joanne L. Yu; James Luyendyk; Nigel Mackman

  Oncogenes, trousseau syndrome, and cancer-related changes in the coagulome of mice and humans

  Cancer Research. 2006;66(22):10643-10646.
  60

• 130.

  2006

  Rolf Dario Frank; Todd Holscher; Gernot Schabbauer; Michael Tencati; Rafal Pawlinski; Jeffrey I. Weitz; Nigel Mackman

  A non-anticoagulant synthetic pentasaccharide reduces inflammation in a murine model of kidney ischemia-reperfusion injury

  Thrombosis and Haemostasis. 2006;96(6):802-806.
  6

• 131.

  2006

  Mausumee Guha; Nigel Mackman

  Erratum: LPS induction of gene expression in human monocytes (Cellular Signalling (2001) 13 (85-94) DOI: 10.1016/S0898-6568(00)00149-2)

  Cellular Signalling. 2006;18(4):E2.
  0

• 132.

  2006

  Rachel Tilley; Nigel Mackman

  Tissue factor in hemostasis and thrombosis

  Seminars in Thrombosis and Hemostasis. 2006;32(1):5-10.
  42

• 133.

  2006

  M. Hayashima; T. Matsushita; N. Mackman; M. Ito; T. Adachi; A. Katsumi; K. Yamamoto; K. Takeshita; T. Kojima; H. Saito; et al.

  Fatal thrombosis of antithrombin-deficient mice is rescued differently in the heart and liver by intercrossing with low tissue factor mice

  Journal of Thrombosis and Haemostasis. 2006;4(1):177-185.
  8

• 134.

  2006

  Nigel Mackman

  Role of tissue factor in hemostasis and thrombosis

  Blood Cells, Molecules, and Diseases. 2006;36(2):104-107.
  59

• 135.

  2006

  James P. Luyendyk; Rachel E. Tilley; Nigel Mackman

  Genetic susceptibility to thrombosis

  Current Atherosclerosis Reports. 2006;8(3):193-197.
  6

• 136.

  2006

  Rachel E. Tilley; Brian Pedersen; Rafal Pawlinski; Yuichiro Sato; Jonathan H. Erlich; Yuechun Shen; Sharlene Day; Ying Huang; Daniel T. Eitzman; et al.

  Atherosclerosis in mice is not affected by a reduction in tissue factor expression

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2006;26(3):555-562.
  15

• 137.

  2006

  I.K. Mullarky; F.M. Szaba; C.G. Winchel; M.A. Parent; L.W. Kummer; N. Mackman; L.L. Johnson; Stephen T. Smiley

  Assays demonstrate the interferon-gamma suppresses infection-stimulated hepatic fibrin deposition by promoting fibrinolysis

  Journal of Thrombosis and Haemostasis. 2006;4(7):1580-1587.
  8

• 138.

  2006

  Yuan Rong; Fang Hu; RuoPan Huang; Nigel Mackman; Jonathan M. Horowitz; Randy L. Jensen; Donald L. Durden; Erwin G. Van Meir; Daniel J. Brat

  Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms

  Cancer Research. 2006;66(14):7067-7074.
  47

• 139.

  2005

  Sharlene M. Day; Jennifer L. Reeve; Brian Pedersen; Diana M. Farris; Daniel D. Myers; Michael Im; Thomas W. Wakefield; Nigel Mackman; William P. Fay

  Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

  Blood. 2005;105(1):192-198.
  158

• 140.

  2005

  Joanne L. Yu; Linda May; Vladimir Lhotak; Siranoush Shahrzad; Senji Shirasawa; Jeffrey I. Weitz; Brenda L. Coomber; Nigel Mackman; Janusz W. Rak

  Oncogenic events regulate tissue factor expression in colorectal cancer cells: Implications for tumor progression and angiogenesis

  Blood. 2005;105(4):1734-1741.
  197

• 141.

  2005

  Brian Pedersen; Todd Holscher; Yuichiro Sato; Rafal Pawlinski; Nigel Mackman

  A balance between tissue factor and tissue factor pathway inhibitor is required for embryonic development and hemostasis in adult mice

  Blood. 2005;105(7):2777-2782.
  56

• 142.

  2005

  David A. Morrow; Sabina A. Murphy; Carolyn H. McCabe; Nigel Mackman; Hing C. Wong; Elliott M. Antman

  Potent inhibition of thrombin with a monoclonal antibody against tissue factor (Sunol-cH36): Results of the PROXIMATE-TIMI 27 trial

  European Heart Journal. 2005;26(7):682-688.
  35

• 143.

  2005

  Gourab Bhattacharjee; Jasimuddin Ahamed; Brian Pedersen; Amr El-Sheikh; Nigel Mackman; Wolfram Ruf; Cheng Liu; Thomas S. Edgington

  Regulation of tissue factor-mediated initiation of the coagulatiion cascade by cell surface Grp78

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25(8):1737-1743.
  29

• 144.

  2005

  Julian Niemetz; Sharlene M. Day; Nigel Mackman; William P. Fay

  Tissue-factor-endowed leukocytes do cause thrombosis [5] (multiple letters)

  Blood. 2005;106(4):1506-1507.
  5

• 145.

  2005

  R.D. Frank; G. Schabbauer; T. Holscher; Y. Sato; M. Tencati; R. Pawlinski; Nigel Mackman

  The synthetic pentasaccharide fondaparinux reduces coagulation, inflammation and neutrophil accumulation in kidney ischemia-reperfusion injury

  Journal of Thrombosis and Haemostasis. 2005;3(3):531-540.
  18

• 146.

  2005

  Motohiro Kamimura; Christiane Viedt; Alexander Dalpke; Michael E. Rosenfeld; Nigel Mackman; David M. Cohen; Erwin Blessing; Michael Preusch; Christian M. Weber; Jörg Kreuzer; et al.

  Interleukin-10 suppresses tissue factor expression in lipopolysaccharide- stimulated macrophages via inhibition of Egr-1 and a serum response element/MEK-ERK1/2 pathway

  Circulation Research. 2005;97(4):305-313.
  32

• 147.

  2005

  Deborah D. Motton; Nigel Mackman; Rachel E. Tilley; John C. Rutledge

  Postprandial elevation of tissue factor antigen in the blood of healthy adults

  Thrombosis and Haemostasis. 2005;94(3):504-509.
  10

• 148.

  2005

  Stuart A. Rushworth; Xi-Lin Chen; Nigel Mackman; Richard M. Ogborne; Maria A. O'Connell

  Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C

  Journal of Immunology. 2005;175(7):4408-4415.
  61

• 149.

  2005

  Nigel Mackman

  Tissue-specific hemostasis in mice

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25(11):2273-2281.
  61

• 150.

  2004

  Rafal Pawlinski; Brian Pedersen; Jonathan Erlich; Nigel Mackman

  Role of tissue factor in haemostasis, thrombosis, angiogenesis and inflammation: Lessons from low tissue factor mice

  Thrombosis and Haemostasis. 2004;92(REV.):70-76.
  17

• 151.

  2004

  Rafal Pawlinski; Brian Pedersen; Gernot Schabbauer; Michael Tencati; Todd Holscher; William Boisvert; Patricia Andrade-Gordon; Rolf Dario Frank; Nigel Mackman

  Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia

  Blood. 2004;103(4):1342-1347.
  149

• 152.

  2004

  Nigel Mackman

  Role of tissue factor in hemostasis, thrombosis, and vascular development

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2004;24(6):1015-1022.
  255

• 153.

  2004

  Rafal Pawlinski; Nigel Mackman

  Tissue factor, coagulation proteases, and protease-activated receptors in endotoxemia and sepsis.

  Critical care medicine. 2004;32(5 Suppl):S293-297.
  51

• 154.

  2004

  K. Veera Reddy; Gourab Bhattacharjee; Gernot Schabbauer; Angela Hollis; Kevin Kempf; Michael Tencati; Maria O'Connell; Mausumee Guha; Nigel Mackman

  Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability

  Journal of Leukocyte Biology. 2004;76(1):145-151.
  22

• 155.

  2004

  Robert T. Pyo; Yuichiro Sato; Nigel Mackman; Mark B. Taubman

  Mice deficient in tissue factor demonstrate attenuated intimal hyperplasia in response to vascular injury and decreased smooth muscle cell migration

  Thrombosis and Haemostasis. 2004;92(3):451-458.
  25

• 156.

  2004

  Rafal Pawlinski; Brian Pedersen; Jonathan Erlich; Nigel Mackman

  Role of tissue factor in haemostasis, thrombosis, angiogenesis and inflammation: Lessons from low tissue factor mice

  Thrombosis and Haemostasis. 2004;92(3):444-450.
  30

• 157.

  2004

  Nigel Mackman

  Mouse models in haemostasis and thrombosis

  Thrombosis and Haemostasis. 2004;92(3):440-443.
  9

• 158.

  2004

  Gernot Schabbauer; Michael Tencati; Brian Pedersen; Rafal Pawlinski; Nigel Mackman

  PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2004;24(10):1963-1969.
  80

• 159.

  2004

  Janet Chou; Nigel Mackman; Glenn Merrill-Skoloff; Brian Pedersen; Barbara C. Furie; Bruce Furie

  Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation

  Blood. 2004;104(10):3190-3197.
  190

• 160.

  2003

  Albert J. Chong; Timothy H. Pohlman; Craig R. Hampton; Akira Shimamoto; Nigel Mackman; Edward D. Verrier

  Tissue factor and thrombin mediate myocardial ischemia-reperfusion injury

  Annals of Thoracic Surgery. 2003;75(2):S649-S655.
  22

• 161.

  2003

  Berend Isermann; Rashmi Sood; Rafal Pawlinski; Mark Zogg; Shawn Kalloway; Jay L. Degen; Nigel Mackman; Hartmut Weiler

  The thrombomodulin-protein C system is essential for the maintenance of pregnancy

  Nature Medicine. 2003;9(3):331-337.
  144

• 162.

  2003

  Florian Bea; Mirja H. Puolakkainen; Timothy McMillen; Francesca N. Hudson; Nigel Mackman; Cho Chou Kuo; Lee Ann Campbell; Michael E. Rosenfeld

  Chlamydia pneumoniae induces tissue factor expression in mouse macrophages via activation of Egr-1 and the MEK-ERK1/2 pathway

  Circulation Research. 2003;92(4):394-401.
  40

• 163.

  2003

  Thorsten Cramer; Yuji Yamanishi; Björn E. Clausen; Irmgard Förster; Rafal Pawlinski; Nigel Mackman; Volker H. Haase; Rudolf Jaenisch; Maripat Corr; Victor Nizet; et al.

  HIF-1α is essential for myeloid cell-mediated inflammation

  Cell. 2003;112(5):645-657.
  621

• 164.

  2003

  T. Cramer; Y. Yamanishi; B.E. Clausen; I. Förster; R. Pawlinski; N. Mackman; V.H. Haase; R. Jaenisch; M. Corr; V. Nizet; et al.

  Erratum: HIF-1α is essential for myeloid cell-mediated inflammation (Cell 112:5 (648))

  Cell. 2003;113(3):419.
  3

• 165.

  2003

  Rafal Pawlinski; Brian Pedersen; Bettina Kehrle; William C. Aird; Rolf D. Frank; Mausumee Guha; Nigel Mackman

  Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model

  Blood. 2003;101(10):3940-3947.
  52

• 166.

  2003

  Nigel Mackman

  How do oxidized phospholipids inhibit LPS signaling?

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2003;23(7):1133-1136.
  9

• 167.

  2003

  Nigel Mackman

  The role of the tissue factor-thrombin pathway in cardiac ischemia-reperfusion injury

  Seminars in Vascular Medicine. 2003;3(2):193-198.
  13

• 168.

  2003

  Taavo Tenno; Fredrik Öberg; Nigel Mackman; Kenneth Nilsson; Agneta Siegbahn

  PML/RARα plays a role for basal activity and retinoid-induced repression of the tissue factor promoter in acute promyelocytic leukemia cells

  Thrombosis and Haemostasis. 2003;90(5):930-939.
  3

• 169.

  2003

  Claudia Marsik; Peter Quehenberger; Nigel Mackman; Bjarne Osterud; Thomas Luther; Bernd Jilma

  Validation of a novel tissue factor assay in experimental human endotoxemia

  Thrombosis Research. 2003;111(4-5):311-315.
  16

• 170.

  2003

  Claudia Marsik; Monika Graninger; Nigel Mackman; Bjarne Osterud; Thomas Luther; Bernd Jilma

  Effects of enalapril on disseminated intravascular thrombin formation during systemic inflammation

  Cardiovascular Research. 2003;60(1):131-135.
  3

• 171.

  2002

  Usha R. Pendurthi; Feng Meng; N. Mackman; L. Vijaya Mohan Rao

  Mechanisms of resveratrol-mediated suppression of tissue factor gene expression

  Thrombosis and Haemostasis. 2002;87(1):155-162.
  30

• 172.

  2002

  Udo Bavendiek; Peter Libby; Meagan Kilbride; Rebecca Reynolds; Nigel Mackman; Uwe Schönbeck

  Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor κB, and Egr-1

  Journal of Biological Chemistry. 2002;277(28):25032-25039.
  84

• 173.

  2002

  R. Pawlinski; A. Fernandes; B. Kehrle; B. Pedersen; G. Parry; J. Erlich; R. Pyo; D. Gutstein; J. Zhang; F. Castellino; et al.

  Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction

  Proceedings of the National Academy of Sciences of the United States of America. 2002;99(24):15333-15338.
  61

• 174.

  2002

  Mausumee Guha; Nigel Mackman

  The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

  Journal of Biological Chemistry. 2002;277(35):32124-32132.
  352

• 175.

  2001

  Els Melis; Lieve Moons; Maria De Mol; Jean-Marc Herbert; Nigel Mackman; Désiré Collen; Peter Carmeliet; Mieke Dewerchin

  Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development

  Biochemical and Biophysical Research Communications. 2001;286(3):580-586.
  38

• 176.

  2001

  S.-F. Yan; T. Fujita; J. Lu; K. Okada; Y.S. Zou; N. Mackman; D.J. Pinsky; D.M. Stern

  Erratum: Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress (Nature Medicine (2000) 6 (13551-1361))

  Nature Medicine. 2001;7(4):509.
  0

• 177.

  2001

  Mausumee Guha; Nigel Mackman

  LPS induction of gene expression in human monocytes

  Cellular Signalling. 2001;13(2):85-94.
  1014

• 178.

  2001

  Thomas Luther; Nigel Mackman

  Tissue factor in the heart: Multiple roles in hemostasis, thrombosis, and inflammation

  Trends in Cardiovascular Medicine. 2001;11(8):307-312.
  19

• 179.

  2001

  Toshiya Nishibe; Graham Parry; Atsushi Ishida; Salim Aziz; Jacqueline Murray; Yatin Patel; Salman Rahman; Kurt Strand; Keiko Saito; Yuji Saito; et al.

  Oncostatin M promotes biphasic tissue factor expression in smooth muscle cells: Evidence for Erk-1/2 activation

  Blood. 2001;97(3):692-699.
  30

• 180.

  2001

  N. Mackman

  Gene targeting in hemostasis. tissue factor.

  Front Biosci. 2001;6:D208-215.
  12

• 181.

  2001

  Mausumee Guha; Maria A. O'Connell; Rafal Pawlinski; Angela Hollis; Patricia McGovern; Shi-Fang Yan; David Stern; Nigel Mackman

  Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression

  Blood. 2001;98(5):1429-1439.
  214

• 182.

  2001

  Nikolaus Marx; Nigel Mackman; Uwe Schönbeck; Nurcan Yilmaz; Vinzenz Hombach; Peter Libby; Jorge Plutzky

  PPARα activators inhibit tissue factor expression and activity in human monocytes

  Circulation. 2001;103(2):213-219.
  121

• 183.

  2000

  J.H. Erlich; E.M. Boyle; J. Labriola; J.C. Kovacich; R.A. Santucci; C. Fearns; E.N. Morgan; W. Yun; T. Luther; et al.

  Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation

  American Journal of Pathology. 2000;157(6):1849-1862.
  118

• 184.

  2000

  Thomas Luther; Dag-Daniel Dittert; Matthias Kotzsch; Jonathan Erlich; Sybille Albrecht; Nigel Mackman; Martin Müller

  Angiogenesis in the neoplastic sequence of Barrett's oesophagus. Correlation with VEGF expression

  Journal of Pathology. 2000;192(1):14-18.
  70

• 185.

  2000

  D.N. Muller; E.M.A. Mervaala; R. Dechend; A. Fiebeler; J.-K. Park; F. Schmidt; J. Theuer; V. Breu; N. Mackman; T. Luther; et al.

  Angiotensin II (AT₁) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy

  American Journal of Pathology. 2000;157(1):111-122.
  66

• 186.

  2000

  Graham C.N. Parry; Nigel Mackman

  Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain

  Journal of Clinical Investigation. 2000;105(11):1547-1554.
  32

• 187.

  2000

  Shi Fang Yan; David J. Pinsky; Nigel Mackman; David M. Stern

  Egr-1: Is it always immediate and early?

  Journal of Clinical Investigation. 2000;105(5):553-554.
  38

• 188.

  2000

  Richard A. Santucci; Jonathan Erlich; Joanne Labriola; Mark Wilson; K.J. Kao; Thomas S. Kickler; Charles Spillert; Nigel Mackman

  Measurement at tissue factor activity in whole blood

  Thrombosis and Haemostasis. 2000;83(3):445-454.
  41

• 189.

  2000

  Ru Liu; Maria O'Connell; Kristen Johnson; Kenneth Pritzker; Nigel Mackman; Robert Terkeltaub

  Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor κB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells

  Arthritis and Rheumatism. 2000;43(5):1145-1155.
  70

• 190.

  2000

  Graciela Krikun; Frederick Schatz; Nigel Mackman; Seth Guller; Rita Demopoulos; Charles J. Lockwood

  Regulation of tissue factor gene expression in human endometrium by transcription factors Sp1 and Sp3

  Molecular Endocrinology. 2000;14(3):393-400.
  53

• 191.

  2000

  Shi-Fang Yan; Tomoyuki Fujita; Jiesheng Lu; Kenji Okada; Yu Shan Zou; Nigel Mackman; David J. Pinsky; David M. Stern

  Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress

  Nature Medicine. 2000;6(12):1355-1361.
  261

• 192.

  2000

  Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Paul J. Godowski; Richard J. Ulevitch; Ulla G. Knaus

  Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway

  Nature Immunology. 2000;1(6):533-540.
  390

• 193.

  2000

  P. Xie; D.D. Browning; N. Hay; N. Mackman; R.D. Ye

  Activation of NF-κB by bradykinin through a Gα(q)- and Gβγ-dependent pathway that involves phosphoinositide 3-kinase and Akt

  Journal of Biological Chemistry. 2000;275(32):24907-24914.
  95

• 194.

  2000

  Shi-Fang Yan; Jiesheng Lu; Yu Shan Zou; Walter Kisiel; Nigel Mackman; Michael Leitges; Susan Steinberg; David Pinsky; David Stern

  Protein kinase C-β and oxygen deprivation. A novel Egr-1-dependent pathway for fibrin deposition in hypoxemic vasculature

  Journal of Biological Chemistry. 2000;275(16):11921-11928.
  40

• 195.

  2000

  Ralf Dechend; Volker Homuth; Gerd Wallukat; Jörg Kreuzer; Jeun Koon Park; Jürgen Theuer; Axel Juepner; Dietrich C. Gulba; Nigel Mackman; Hermann Haller; et al.

  AT₁ receptor agonistic antibodies from preeclamptic patients cause vascular cells to express tissue factor

  Circulation. 2000;101(20):2382-2387.
  126

• 196.

  2000

  Shi-Fang Yan; Jiesheng Lu; Linna Xu; Yu Shan Zou; Joern Tongers; Walter Kisiel; Nigel Mackman; David J. Pinsky; David M. Stern

  Pulmonary expression of early growth response-1: Biphasic time course and effect of oxygen concentration

  Journal of Applied Physiology. 2000;88(6):2303-2309+2302.
  32

• 197.

  2000

  Errol S. Wijelath; Toshiya Nishibe; Graham Parry; Salim Aziz; Atsushi Ishida; Keiko Saito; Yuji Saito; Jacqueline Murray; Yatin Patel; Salman Rahman; et al.

  Oncostatin m promotes prolonged tissue factor expression in smooth muscle cells: evidence for erk-1/2 activation of nf-kb

  Blood. 2000;96(11 PART I):42a.
  0

• 198.

  2000

  N. Mackman

  Lipopolysaccharide induction of gene expression in human monocytic cells

  Immunologic Research. 2000;21(2-3):247-251.
  28

• 199.

  1999

  Yiyang Xia; Shizhong Chen; Yibin Wang; Nigel Mackman; George Ku; David Lo; Lili Feng

  RelB modulation of IκBα stability as a mechanism of transcription suppression of interleukin-1α (IL-1α), IL-1β, and tumor necrosis factor alpha in fibroblasts

  Molecular and Cellular Biology. 1999;19(11):7688-7696.
  47

• 200.

  1999

  Shi-Fang Yan; Nigel Mackman; Walter Kisiel; David M. Stern; David J. Pinsky

  Hypoxia/hypoxemia-induced activation of the procoagulant pathways and the pathogenesis of ischemia-associated thrombosis

  Arteriosclerosis, Thrombosis, and Vascular Biology. 1999;19(9):2029-2035.
  69

• 201.

  1999

  Jonathan Erlich; Colleen Fearns; John Mathison; Richard J. Ulevitch; Nigel Mackman

  Lipopolysaccharide induction of tissue factor expression in rabbits

  Infection and Immunity. 1999;67(5):2540-2546.
  80

• 202.

  1999

  Parul Houston; Marion C. Dickson; Valerie Ludbrook; Brian White; Jean-Luc Schwachtgen; John H. McVey; Nigel Mackman; Jason M. Reese; Daniel G. Gorman; Callum Campbell; et al.

  Fluid shear stress induction of the tissue factor promoter in vitro and in vivo is mediated by Egr-1

  Arteriosclerosis, Thrombosis, and Vascular Biology. 1999;19(2):281-289.
  64

• 203.

  1999

  J. Erlich; G.C.N. Parry; C. Fearns; M. Muller; P. Carmeliet; T. Luther; N. Mackman

  Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation

  Proceedings of the National Academy of Sciences of the United States of America. 1999;96(14):8138-8143.
  70

• 204.

  1999

  Shi-Fang Yan; Jiesheng Lu; Yu Shan Zou; Jae Soh-Won; David M. Cohen; Peter M. Buttrick; Denise R. Cooper; Susan F. Steinberg; Nigel Mackman; David J. Pinsky; et al.

  Hypoxia-associated induction of early growth response-1 gene expression

  Journal of Biological Chemistry. 1999;274(21):15030-15040.
  175

• 205.

  1999

  Norbert Leitinger; Timothy R. Tyner; Laura Oslund; Cristina Rizza; Ganesamoorthy Subbanagounder; Hans Lee; Peggy T. Shih; Nigel Mackman; Gabor Tigyi; Mary C. Territo; et al.

  Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils

  Proceedings of the National Academy of Sciences of the United States of America. 1999;96(21):12010-12015.
  164

• 206.

  1998

  Shi-Fang Yan; Yu Shan Zou; Yun Gao; Chao Zhai; Nigel Mackman; Stephen L. Lee; Jeffrey Milbrandt; David Pinsky; Walter Kisiel; David Stern

  Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia

  Proceedings of the National Academy of Sciences of the United States of America. 1998;95(14):8298-8303.
  138

• 207.

  1998

  Jan Bohuslav; V.V. Kravchenko; G.G. Parry; N. Mackman; R.J. Ulgvitch

  p50/NFkB is essential for downregulation of the TNF promoter at the LPS tolerant state

  FASEB Journal. 1998;12(8):A1318.
  0

• 208.

  1998

  Graciela Krikun; Frederick Schatz; Nigel Mackman; Seth Guller; Charles J. Lockwood

  Transcriptional regulation of the tissue factor gene by progestins in human endometrial stromal cells

  Journal of Clinical Endocrinology and Metabolism. 1998;83(3):926-930.
  27

• 209.

  1998

  Bruce Fowler; Nigel Mackman; Robert J. Parmer; Lindsey A. Miles

  Binding of human single chain urokinase to chinese hamster ovary cells and cloning of hamster u-PAR

  Thrombosis and Haemostasis. 1998;80(1):148-154.
  20

• 210.

  1998

  Graham C. N. Parry; Nigel Mackman

  NF-κB mediated transcription in human monocytic cells and endothelial cells

  Trends in Cardiovascular Medicine. 1998;8(3):138-142.
  10

• 211.

  1998

  Graham C.N. Parry; Jonathan H. Erlich; Peter Carmeliet; Thomas Luther; Nigel Mackman

  Low levels of tissue factor are compatible with development and hemostasis in mice

  Journal of Clinical Investigation. 1998;101(3):560-569.
  121

• 212.

  1998

  Jan Bohuslav; Vladimir V. Kravchenko; Graham C.N. Parry; Jonathan H. Erlich; Steve Gerondakis; Nigel Mackman; Richard J. Ulevitch

  Regulation of an essential innate immune response by the p50 subunit of NF-κB

  Journal of Clinical Investigation. 1998;102(9):1645-1652.
  175

• 213.

  1998

  Maria A. O'Connell; Brydon L. Bennett; Frank Mercurio; Anthony M. Manning; Nigel Mackman

  Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells

  Journal of Biological Chemistry. 1998;273(46):30410-30414.
  139

• 214.

  1998

  Paul Oeth; Jin Yao; Sao-Tah Fan; Nigel Mackman

  Retinoic acid selectively inhibits lipopolysaccharide induction of tissue factor gene expression in human monocytes

  Blood. 1998;91(8):2857-2865.
  25

• 215.

  1997

  Peter Carmeliet; Lieve Moons; M. Dewerchin; Nigel Mackman; Thomas Luther; Georg Breier; V. Ploplis; M. Müller; A. Nagy; E. Plow; et al.

  Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system

  Annals of the New York Academy of Sciences. 1997;811:191-206.
  100

• 216.

  1997

  Nigel Mackman

  Regulation of the tissue factor gene

  Thrombosis and Haemostasis. 1997;78(1):747-754.
  201

• 217.

  1997

  Jin Yao; Nigel Mackman; Thomas S. Edgington; Sao-Tah Fan

  Lipopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells: Regulation by Egr-1, c-Jun, and NF-κB transcription factors

  Journal of Biological Chemistry. 1997;272(28):17795-17801.
  345

• 218.

  1997

  Angelika Bierhaus; Youming Zhang; Peter Quehenberger; Thomas Luther; Michael Haase; Martin Müller; Nigel Mackman; Reinhard Ziegler; Peter P. Nawroth

  The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-κB

  Thrombosis and Haemostasis. 1997;77(4):772-782.
  118

• 219.

  1997

  Ming-Chao Lin; Fanny Almus-Jacobs; Hsuan-Hsu Chen; Graham C.N. Parry; Nigel Mackman; John Y.-J. Shyy; Shu Chien

  Shear stress induction of the tissue factor gene

  Journal of Clinical Investigation. 1997;99(4):737-744.
  155

• 220.

  1997

  Paul Oeth; Graham C. N. Parry; Nigel Mackman

  Regulation of the tissue factor gene in human monocytic cells: Role of AP-1, NF-κB/Rel, and Sp1 proteins in uninduced and lipopolysaccharide- induced expression

  Arteriosclerosis, Thrombosis, and Vascular Biology. 1997;17(2):365-374.
  95

• 221.

  1997

  Graham C. N. Parry; Nigel Mackman

  Role of Cyclic AMP Response Element-Binding Protein in Cyclic AMP Inhibition of NF-κB-Mediated Transcription

  Journal of Immunology. 1997;159(11):5450-5456.
  173

• 222.

  1997

  Graham C. N. Parry; Nigel Mackman

  Transcriptional regulation of the human urokinase-type plasminogen activator receptor gene

  Fibrinolysis and Proteolysis. 1997;11(SUPPL. 3):4.
  0

• 223.

  1997

  Korbinian Brand; Tamara Eisele; Ursula Kreusel; Michael Page; Sharon Page; Monika Haas; Astrid Gerling; Christian Kaltschmidt; Franz-Josef Neumann; et al.

  Dysregulation of monocytic nuclear factor-κB by oxidized low-density lipoprotein

  Arteriosclerosis, Thrombosis, and Vascular Biology. 1997;17(10):1901-1909.
  97

• 224.

  1996

  P. Carmeliet; N. Mackman; S. Wyns; E. Rosen; L. Kieckens; T. Luther; T. Edgington; D. Collen

  Inactivation of the tissue factor gene results in embryonic lethality due to abnormal vasculogenesis

  Fibrinolysis. 1996;10(SUPPL. 3):20.
  0

• 225.

  1996

  Thomas Luther; Conrad Flössel; Nigel Mackman; Angelika Bierhaus; Michael Kasper; Sybille Albrecht; E. Helene Sage; Luisa Iruela-Arispe; Heinz Grossmann; Arne Ströhlein; et al.

  Tissue factor expression during human and mouse development

  American Journal of Pathology. 1996;149(1):101-113.
  71

• 226.

  1996

  Peter Carmeliet; Nigel Mackman; Lieve Moons; Thomas Luther; Pierre Gressens; Ilse Van Vlaenderen; Hilde Demunck; Michael Kasper; Georg Breier; Philippe Evrard; et al.

  Role of tissue factor in embryonic blood vessel development

  Nature. 1996;383(6595):73-75.
  434

• 227.

  1996

  Ronald R. Cobb; Katherine A. Felts; Graham C. N. Parry; Nigel Mackman

  Proteasome inhibitors block VCAM-1 and ICAM-1 gene expression in endothelial cells without affecting nuclear translocation of nuclear factor-κB

  European Journal of Immunology. 1996;26(4):839-845.
  39

• 228.

  1996

  Ronald R. Cobb; Katherine A. Felts; Thomas C. McKenzie; Graham C. N. Parry; Nigel Mackman

  A benzothiophene-carboxamide is a potent inhibitor of IL-1β induced VCAM-1 gene expression in human endothelial cells

  FEBS Letters. 1996;382(3):323-326.
  21

• 229.

  1996

  Veronique Ollivier; Graham C. N. Parry; Ronald R. Cobb; Dominique De Prost; Nigel Mackman

  Elevated cyclic AMP inhibits NF-κB-mediated transcription in human monocytic cells and endothelial cells

  Journal of Biological Chemistry. 1996;271(34):20828-20835.
  231

• 230.

  1996

  Daniel Gonzalez-Dunia; Michael Eddleston; Nigel Mackman; Kathryn Carbone; Juan Carlos De La Torre

  Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with borna disease virus

  Journal of Virology. 1996;70(9):5812-5820.
  22

• 231.

  1996

  Mayra Yebra; Graham C.N. Parry; Staffan Strömblad; Nigel Mackman; Steven Rosenberg; Barbara M. Mueller; David A. Cheresh

  Requirement of receptor-bound urokinase-type plasminogen activator for integrin αvβ5-directed cell migration

  Journal of Biological Chemistry. 1996;271(46):29393-29399.
  191

• 232.

  1996

  Irene M. Lang; Nigel Mackman; Jolene M. Kriett; Kenneth M. Moser; Raymond R. Schleef

  Prothrombotic activation of pulmonary arterial endothelial cells in a patient with tuberculosis

  Human Pathology. 1996;27(4):423-427.
  12

• 233.

  1996

  Ronald R. Cobb; Katherine A. Felts; Graham C. N. Parry; Nigel Mackman

  D609, a phosphatidylcholine-specific phospholipase C inhibitor, blocks interleukin-1β-induced vascular cell adhesion molecule 1 gene expression in human endothelial cells

  Molecular Pharmacology. 1996;49(6):998-1004.
  28

• 234.

  1996

  Nigel Mackman

  Regulation of tissue factor gene expression in human monocytic and endothelial cells

  Haemostasis. 1996;26(SUPPL. 1):17-19.
  30

• 235.

  1996

  Mei-Zhen Cui; Graham C. N. Parry; Paul Oeth; Heike Larson; Melissa Smith; Ruo-Pan Huang; Eileen D. Adamson; Nigel Mackman

  Transcriptional regulation of the tissue factor gene in human epithelial cells is mediated by Sp1 and EGR-1

  Journal of Biological Chemistry. 1996;271(5):2731-2739.
  132

• 236.

  1995

  A. Bierhaus; Y. Zhang; Y. Deng; N. Mackman; P. Quehenberger; M. Haase; T. Luther; M. Muller; H. Bohrer; J. Greten; et al.

  Mechanism of the tumor necrosis factor α-mediated induction of endothelial tissue factor

  Journal of Biological Chemistry. 1995;270(44):26419-26432.
  114

• 237.

  1995

  A. Bierhaus; C.J. Hemmer; N. Mackman; R. Kutob; R. Ziegler; M. Dietrich; P.P. Nawroth

  Antiparasitic treatment of patients with P. falciparum malaria reduces the ability of patient serum to induce tissue factor by decreasing NF-κB activation

  Thrombosis and Haemostasis. 1995;73(1):39-48.
  20

• 238.

  1995

  P. Oeth; N. Mackman

  Salicylates inhibit lipopolysaccharide-induced transcriptional activation of the tissue factor gene in human monocytic cells

  Blood. 1995;86(11):4144-4152.
  70

• 239.

  1995

  P.G. Tipping; J.H. Erlich; J. Apostolopoulos; N. Mackman; D. Loskutoff; S.R. Holdsworth

  Glomerular tissue factor expression in crescentic glomerulonephritis: Correlations between antigen, activity, and mRNA

  American Journal of Pathology. 1995;147(6):1736-1748.
  41

• 240.

  1995

  S.-T. Fan; N. Mackman; M.-Z. Cui; T.S. Edgington

  Integrin regulation of an inflammatory effector gene: Direct induction of the tissue factor promoter by engagement of β1 or α4 integrin chains

  Journal of Immunology. 1995;154(7):3266-3274.
  64

• 241.

  1995

  S.M. Quirk; B.T. Pentecost; N. Mackman; D.J. Loskutoff; S. Hartzell; K.P. Henrikson

  The regulation of uterine tissue factor by estrogen

  Endocrine. 1995;3(2):177-184.
  6

• 242.

  1995

  G.C.N. Parry; N. Mackman

  Transcriptional regulation of tissue factor expression in human endothelial cells

  Arteriosclerosis, Thrombosis, and Vascular Biology. 1995;15(5):612-621.
  141

• 243.

  1995

  N. Mackman

  Regulation of the tissue factor gene

  FASEB Journal. 1995;9(10):883-889.
  203

• 244.

  1995

  M.A. Olman; N. Mackman; C.L. Gladson; K.M. Moser; D.J. Loskutoff

  Changes in procoagulant and fibrinolytic gene expression during bleomycin- induced lung injury in the mouse

  Journal of Clinical Investigation. 1995;96(3):1621-1630.
  125

• 245.

  1994

  N. Mackman

  Protease inhibitors block lipopolysaccharide induction of tissue factor gene expression in human monocytic cells by preventing activation of c- Rel/p65 heterodimers

  Journal of Biological Chemistry. 1994;269(42):26363-26367.
  51

• 246.

  1994

  Graham C. N. Parry; Nigel Mackman

  A set of inducible genes expressed by activated human monocytic and endothelial cells contain κB-like sites that specifically bind c-Rel-p65 heterodimers

  Journal of Biological Chemistry. 1994;269(33):20823-20825.
  116

• 247.

  1994

  M.-Z. Cui; G.C.N. Parry; T.S. Edgington; N. Mackman

  Regulation of tissue factor gene expression in epithelial cells: Induction by serum and phorbol 12-myristate 13-acetate

  Arteriosclerosis and Thrombosis. 1994;14(5):807-814.
  33

• 248.

  1994

  S. Steinemann; R.J. Ulevitch; N. Mackman

  Role of the lipopolysaccharide (LPS)-binding protein/CD14 pathway in LPS induction of tissue factor expression in monocytic cells

  Arteriosclerosis and Thrombosis. 1994;14(7):1202-1209.
  38

• 249.

  1994

  K. Brand; C.L. Banka; N. Mackman; R.A. Terkeltaub; S.-T. Fan; L.K. Curtiss

  Oxidized LDL enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes

  Arteriosclerosis and Thrombosis. 1994;14(5):790-797.
  89

• 250.

  1994

  Paul A. Oeth; Graham C. N. Parry; Charles Kunsch; Pascale Nantermet; Craig A. Rosen; Nigel Mackman

  Lipopolysaccharide induction of tissue factor gene expression in monocytic cells is mediated by binding of c-Rel/p65 heterodimers to a κB-like site

  Molecular and Cellular Biology. 1994;14(6):3772-3781.
  90

• 251.

  1993

  M. Eddleston; J.C. De la Torre; M.B.A. Oldstone; D.J. Loskutoff; T.S. Edgington; N. Mackman

  Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis

  Journal of Clinical Investigation. 1993;92(1):349-358.
  79

• 252.

  1993

  K. Brand; N. Mackman; L.K. Curtiss

  Interferon-γ inhibits macrophage apolipoprotein E production by posttranslational mechanisms

  Journal of Clinical Investigation. 1993;91(5):2031-2039.
  53

• 253.

  1993

  S.-T. Fan; A.A. Brian; B.A. Lollo; N. MackMan; N.L. Shen; T.S. Edgington

  CD11a/CD18 (LFA-1) integrin engagement enhances biosynthesis of early cytokines by activated T cells

  Cellular Immunology. 1993;148(1):48-59.
  11

• 254.

  1993

  J.-D. Lee; V. Kravchenko; T.N. Kirkland; J. Han; N. Mackman; A. Moriarty; D. Leturcq; P.S. Tobias; R.J. Ulevitch

  Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin

  Proceedings of the National Academy of Sciences of the United States of America. 1993;90(21):9930-9934.
  134

• 255.

  1993

  V. Ollivier; S. Houssaye; C. Ternisien; A. Leon; H. De Verneuil; C. Elbim; N. Mackman; T.S. Edgington; D. De Prost

  Endotoxin-induced tissue factor messenger RNA in human monocytes is negatively regulated by a cyclic AMP-dependent mechanism

  Blood. 1993;81(4):973-979.
  44

• 256.

  1993

  Nigel Mackman; Michael S. Sawdey; Mark R. Keeton; David J. Loskutoff

  Murine tissue factor gene expression in vivo: Tissue and cell specificity and regulation by lipopolysaccharide

  American Journal of Pathology. 1993;143(1):76-84.
  76

• 257.

  1992

  N. Mackman; S. Imes; W.H. Maske; B. Taylor; A.J. Lusis; T.A. Drake

  Structure of the murine tissue factor gene: Chromosome location and conservation of regulatory elements in the promoter

  Arteriosclerosis and Thrombosis. 1992;12(4):474-483.
  15

• 258.

  1992

  T.S. Edgington; N. Mackman; S.T. Fan; W. Ruf

  Cellular immune and cytokine pathways resulting in tissue factor expression and relevance to septic shock

  Nouvelle Revue Francaise d'Hematologie. 1992;34(SUPPL.):S15-S17.
  41

• 259.

  1991

  N. Mackman; K. Brand; T.S. Edgington

  Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor κB binding sites

  Journal of Experimental Medicine. 1991;174(6):1517-1526.
  227

• 260.

  1991

  T.S. Edgington; W. Ruf; A. Rehemtulla; N. Mackman

  The molecular biology of initiation of coagulation by tissue factor

  Current Studies in Hematology and Blood Transfusion. 1991;(58):15-21.
  23

• 261.

  1991

  K. Brand; B.J. Fowler; T.S. Edgington; N. Mackman

  Tissue factor mRNA in THP-1 monocytic cells is regulated at both transcriptional and posttranscriptional levels in response to lipopolysaccharide

  Molecular and Cellular Biology. 1991;11(9):4732-4738.
  84

• 262.

  1991

  T.S. Edgington; N. Mackman; K. Brand; W. Ruf

  The structural biology of expression and function of tissue factor

  Thrombosis and Haemostasis. 1991;66(1):67-79.
  396

• 263.

  1991

  Brian S. Andrews; Alnawaz Rehemtulla; Bruce J. Fowler; Thomas S. Edgington; Nigei Mackman

  Conservation of tissue factor primary sequence among three mammalian species

  Gene. 1991;98(2):265-269.
  25

• 264.

  1990

  N. Mackman; B.J. Fowler; T.S. Edgington; J.H. Morrissey

  Functional analysis of the human tissue factor promoter and induction by serum

  Proceedings of the National Academy of Sciences of the United States of America. 1990;87(6):2254-2258.
  47

• 265.

  1989

  N. Mackman; J.H. Morrissey; T.S. Edgington

  The molecular biology of tissue factor

  Hamostaseologie. 1989;9(3):151-156.
  0

• 266.

  1989

  Nigel Mackman; James H. Morrissey; Bruce Fowler; Thomas S. Edgington

  Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade

  Biochemistry. 1989;28(4):1755-1762.
  103

• 267.

  1989

  J.H. Morrissey; S.A. Gregory; N. Mackman; T.S. Edgington

  Tissue factor regulation and gene organization.

  Oxford surveys on eukaryotic genes. 1989;6:67-84.
  10

• 268.

  1989

  L. Gray; K. Baker; B. Kenny; N. Mackman; R. Haigh; I.B. Holland

  A novel C-terminal signal sequence targets Escherichia coli haemolysin directly to the medium

  Journal of Cell Science. 1989;93(SUPPL. 11):45-57.
  24

• 269.

  1988

  S. Bhakdi; N. Mackman; G. Menestrina; L. Gray; F. Hugo; W. Seeger; I.B. Holland

  The hemolysin of Escherichia coli

  European Journal of Epidemiology. 1988;4(2):135-143.
  19

• 270.

  1988

  S. Bhakdi; N. Mackman; G. Menestrina; F. Hugo; W. Seeger; I.B. Holland

  Mechanism of cell damage by E. coli hemolysin

  Immunitat und Infektion. 1988;16(2):41-48.
  0

• 271.

  1987

  N. Mackman; K. Baker; L. Gray; R. Haigh; J.M. Nicaud; I.B. Holland

  Release of a chimeric protein into the medium from Escherichia coli using the C-terminal secretion signal of haemolysin.

  EMBO Journal. 1987;6(9):2835-2841.
  36

• 272.

  1987

  Karen Baker; Nigel Mackman; I. Barry Holland

  Genetics and biochemistry of the assembly of proteins into the outer membrane of E. coli

  Progress in Biophysics and Molecular Biology. 1987;49(2-3):89-115.
  7

• 273.

  1987

  K. Baker; N. Mackman; M. Jackson; I.B. Holland

  Role of secA and secY in protein export as revealed by studies of tonA assembly into the outer membrane of Escherichia coli

  Journal of Molecular Biology. 1987;198(4):693-703.
  2

• 274.

  1987

  Gianfranco Menestrina; Nigel Mackman; Ian Barry Holland; Sucharit Bhakdi

  Escherichia coli haemolysin forms voltage-dependent ion channels in lipid membranes

  BBA - Biomembranes. 1987;905(1):109-117.
  29

• 275.

  1986

  N. Mackman; J.M. Nicaud; L. Gray; I.B. Holland

  Secretion of haemolysin by Escherichia coli.

  Current topics in microbiology and immunology. 1986;125:159-181.
  28

• 276.

  1986

  J.M. Nicaud; N. Mackman; I.B. Holland

  Current status of secretion of foreign proteins by microorganisms

  Journal of Biotechnology. 1986;3(5-6):255-270.
  8

• 277.

  1986

  S. Bhakdi; N. Mackman; J.-M. Nicaud; I.B. Holland

  Escherichia coli hemolysin may damage target cell membranes by generating transmembrane pores

  Infection and Immunity. 1986;52(1):63-69.
  122

• 278.

  1986

  L. Gray; N. Mackman; J.-M. Nicaud; I.B. Holland

  The carboxy-terminal region of haemolysin 2001 is required for secretion of the toxin from Escherichia coli

  MGG Molecular & General Genetics. 1986;205(1):127-133.
  26

• 279.

  1986

  J.-M. Nicaud; N. Mackman; L. Gray; I.B. Holland

  The C-terminal, 23 kDa peptide of E. coli haemolysin 2001 contains all the information necessary for its secretion by the haemolysin (Hly) export machinery

  FEBS Letters. 1986;204(2):331-335.
  19

• 280.

  1985

  J.M. Nicaud; N. Mackman; L. Gray; I.B. Holland

  Regulation of haemolysin synthesis in E. coli determined by HLY genes of human origin

  Molecular and General Genetics. 1985;199(1):111-116.
  3

• 281.

  1985

  J.M. Nicaud; N. Mackman; L. Gray; I.B. Holland

  Characterisation of HlyC and mechanism of activation and secretion of haemolysin from E. coli 2001

  FEBS Letters. 1985;187(2):339-344.
  22

• 282.

  1985

  N. Mackman; J.M. Nicaud; L. Gray; I.B. Holland

  Genetical and functional organisation of the Escherichia coli haemolysin determinant 2001

  Molecular and General Genetics. 1985;201(2):282-288.
  27

• 283.

  1985

  J.-M. Nicaud; N. Mackman; I.B. Holland

  Amplification of synthesis and secretion of haemolysin using a run-away plasmid in Escherichia coli

  Journal of Biotechnology. 1985;3(3):175-183.
  1

• 284.

  1985

  N. Mackman; J.-M. Nicaud; L. Gray; I.B. Holland

  Identification of polypeptides required for the export of haemolysin 2001 from E. coli

  Molecular and General Genetics. 1985;201(3):529-536.
  14

• 285.

  1984

  N. Mackman; I.B. Holland

  Functional characterization of a cloned haemolysin determinant from E. coli of human origin, encoding information for the secretion of a 107K polypeptide

  Molecular and General Genetics. 1984;196(1):129-134.
  8

• 286.

  1984

  N. Mackman; I.B. Holland

  Secretion of a 107 K Dalton polypeptide into the medium from a haemolytic E. coli K12 strain

  Molecular and General Genetics. 1984;193(2):312-315.
  3