Yue Xiong

UNCCH, School of Medicine, Biochemistry and Biophysics

• Home
• Expert Overview
• Profile
• Publications
• Grants
• Patents
• Similar Experts
• Journals
• Trends
• Institutional Network
• Coauthor Network
• Research Network

Yue Xiong

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Biochemistry and Biophysics
  
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Lineberger Comprehensive Cancer Center – Administration and Program Leaders
  
  

Help us refine your profile

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

  Select All    |   Export

• 1.

  2013

  Robert J. Duronio; Yue Xiong

  Signaling pathways that control cell proliferation

  Cold Spring Harbor Perspectives in Biology. 2013;5(3).
  0

• 2.

  2013

  Hai-Xin Yuan; Yue Xiong; Kun-Liang Guan

  Nutrient Sensing, Metabolism, and Cell Growth Control

  Molecular Cell. 2013;49(3):379-387.
  0

• 3.

  2013

  H. Yang; Y. Liu; F. Bai; J.-Y. Zhang; S.-H. Ma; J. Liu; Z.-D. Xu; H.-G. Zhu; Z.-Q. Ling; D. Ye; et al.

  Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

  Oncogene. 2013;32(5):663-669.
  6

• 4.

  2013

  Di Zhao; Shao-Wu Zou; Ying Liu; Xin Zhou; Yan Mo; Ping Wang; Yan-Hui Xu; Bo Dong; Yue Xiong; Qun-Ying Lei; et al.

  Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic Cancer

  Cancer Cell. 2013.
  0

• 5.

  2012

  Hui Yang; Dan Ye; Kun-Liang Guan; Yue Xiong

  IDH1 and IDH2 mutations in tumorigenesis: Mechanistic insights and clinical perspectives

  Clinical Cancer Research. 2012;18(20):5562-5571.
  3

• 6.

  2012

  Wei Huang; Xianbo Lv; Chenying Liu; Zhengyu Zha; Heng Zhang; Ying Jiang; Yue Xiong; Qun-Ying Lei; Kun-Liang Guan

  The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCF ^β-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition

  Journal of Biological Chemistry. 2012;287(31):26245-26253.
  2

• 7.

  2012

  Yue Xiong; Kun-Liang Guan

  Mechanistic insights into the regulation of metabolic enzymes by acetylation

  Journal of Cell Biology. 2012;198(2):155-164.
  4

• 8.

  2012

  P Wang; Q Dong; C Zhang; P-F Kuan; Y Liu; W R Jeck; J B Andersen; W Jiang; G L Savich; T-X Tan; et al.

  Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

  Oncogene. 2012.
  4

• 9.

  2012

  Dan Ye; Yue Xiong; Kun-Liang Guan

  The mechanisms of IDH mutations in tumorigenesis

  Cell Research. 2012;22(7):1102-1104.
  0

• 10.

  2012

  Mengtao Xiao; Hui Yang; Wei Xu; Shenghong Ma; Huaipeng Lin; Honguang Zhu; Lixia Liu; Ying Liu; Chen Yang; Yanhui Xu; et al.

  Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

  Genes and Development. 2012;26(12):1326-1338.
  9

• 11.

  2012

  Eric K. Oermann; Jing Wu; Kun-Liang Guan; Yue Xiong

  Alterations of metabolic genes and metabolites in cancer

  Seminars in Cell and Developmental Biology. 2012;23(4):370-380.
  5

• 12.

  2012

  Michele D. Kassmeier; Koushik Mondal; Victoria L. Palmer; Prafulla Raval; Sushil Kumar; Greg A. Perry; Dirk K. Anderson; Pawel Ciborowski; Sarah Jackson; Yue Xiong; et al.

  VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity

  EMBO Journal. 2012;31(4):945-958.
  2

• 13.

  2012

  Kyunghwan Kim; Kyu Heo; Jongkyu Choi; Sarah Jackson; Hyunjung Kim; Yue Xiong; Woojin An

  Vpr-binding protein antagonizes p53-mediated transcription via Direct interaction with H3 tail

  Molecular and Cellular Biology. 2012;32(4):783-796.
  1

• 14.

  2012

  Tengfei Zhang; Shiwen Wang; Yan Lin; Wei Xu; Dan Ye; Yue Xiong; Shimin Zhao; Kun-Liang Guan

  Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1

  Cell Metabolism. 2012;15(1):75-87.
  3

• 15.

  2012

  Xin Zhou; Ting-Ting Li; Xu Feng; Esther Hsiang; Yue Xiong; Kun-Liang Guan; Qun-Ying Lei

  Targeted polyubiquitylation of RASSF1C by the Mule and SCF ^β-TrCP ligases in response to DNA damage

  Biochemical Journal. 2012;441(1):227-236.
  1

• 16.

  2011

  Tadashi Nakagawa; Yue Xiong

  Chromatin regulation by CRL4 E3 ubiquitin ligases: CUL4B targets WDR5 ubiquitylation in the nucleus

  Cell Cycle. 2011;10(24):4197-4198.
  0

• 17.

  2011

  Tadashi Nakagawa; Yue Xiong

  X-Linked Mental Retardation Gene CUL4B Targets Ubiquitylation of H3K4 Methyltransferase Component WDR5 and Regulates Neuronal Gene Expression

  Molecular Cell. 2011;43(3):381-391.
  12

• 18.

  2011

  Wenqing Jiang; Shiwen Wang; Mengtao Xiao; Yan Lin; Lisha Zhou; Qunying Lei; Yue Xiong; Kun-Liang Guan; Shimin Zhao

  Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

  Molecular Cell. 2011;43(1):33-44.
  22

• 19.

  2011

  Tiffany Hung; Yulei Wang; Michael F. Lin; Ashley K. Koegel; Yojiro Kotake; Gavin D. Grant; Hugo M. Horlings; Nilay Shah; Christopher Umbricht; Pei Wang; et al.

  Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

  Nature Genetics. 2011;43(7):621-629.
  46

• 20.

  2011

  Lei Lv; Dong Li; Di Zhao; Ruiting Lin; Yajing Chu; Heng Zhang; Zhengyu Zha; Ying Liu; Zi Li; Yanping Xu; et al.

  Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth

  Molecular Cell. 2011;42(6):719-730.
  41

• 21.

  2011

  Yaohui Chen; Jinye Zhang; Yan Lin; Qunying Lei; Kun-Liang Guan; Shimin Zhao; Yue Xiong

  Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

  EMBO Reports. 2011;12(6):534-541.
  31

• 22.

  2011

  Y. Kotake; T. Nakagawa; K. Kitagawa; S. Suzuki; N. Liu; M. Kitagawa; Y. Xiong

  Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

  Oncogene. 2011;30(16):1956-1962.
  69

• 23.

  2011

  Xin-Hai Pei; Feng Bai; Zhijun Li; Matthew D. Smith; Gabrielle Whitewolf; Ran Jin; Yue Xiong

  Cytoplasmic CUL9/PARC ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis

  Cancer Research. 2011;71(8):2969-2977.
  3

• 24.

  2011

  Yaxue Zeng; Yojiro Kotake; Xin-Hai Pei; Matthew D. Smith; Yue Xiong

  p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb

  Cancer Research. 2011;71(7):2781-2792.
  6

• 25.

  2011

  Chen-Ying Liu; Xianbo Lv; Tingting Li; Yanping Xu; Xin Zhou; Shimin Zhao; Yue Xiong; Qun-Ying Lei; Kun-Liang Guan

  PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ

  Journal of Biological Chemistry. 2011;286(7):5558-5566.
  12

• 26.

  2011

  Kun-Liang Guan; Yue Xiong

  Regulation of intermediary metabolism by protein acetylation

  Trends in Biochemical Sciences. 2011;36(2):108-116.
  50

• 27.

  2011

  Wei Xu; Hui Yang; Ying Liu; Ying Yang; Ping Wang; Se-Hee Kim; Shinsuke Ito; Chen Yang; Pu Wang; Meng-Tao Xiao; et al.

  Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

  Cancer Cell. 2011;19(1):17-30.
  195

• 28.

  2011

  Y. Xiong; Q.-Y. Lei; S. Zhao; K.-L. Guan

  Regulation of glycolysis and gluconeogenesis by acetylation of PKM and PEPCK

  Cold Spring Harbor Symposia on Quantitative Biology. 2011;76:285-289.
  0

• 29.

  2010

  Jun Yan; Yue Xiong

  Targeted Ubiquitylation: The Prey Becomes Predator

  Molecular Cell. 2010;40(6):853-855.
  2

• 30.

  2010

  Chen-Ying Liu; Zheng-Yu Zha; Xin Zhou; Heng Zhang; Wei Huang; Di Zhao; Tingting Li; Siew Wee Chan; Chun Jye Lim; Wanjin Hong; et al.

  The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF^β-TrCP E3 ligase

  Journal of Biological Chemistry. 2010;285(48):37159-37169.
  28

• 31.

  2010

  Yue Xiong

  Targeting p21 Degradation Locally

  Developmental Cell. 2010;19(5):641-643.
  1

• 32.

  2010

  Hyun O. Lee; Sima J. Zacharek; Yue Xiong; Robert J. Duronio

  Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase

  Molecular Biology of the Cell. 2010;21(21):3639-3653.
  7

• 33.

  2010

  Kun-Liang Guan; Wei Yu; Yan Lin; Yue Xiong; Shimin Zhao

  Generation of acetyllysine antibodies and affinity enrichment of acetylated peptides.

  Nature protocols. 2010;5(9):1583-1595.
  5

• 34.

  2010

  Qijun Wang; Yakun Zhang; Chen Yang; Hui Xiong; Yan Lin; Jun Yao; Hong Li; Lu Xie; Wei Zhao; Yufeng Yao; et al.

  Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux

  Science. 2010;327(5968):1004-1007.
  172

• 35.

  2010

  Shimin Zhao; Wei Xu; Wenqing Jiang; Wei Yu; Yan Lin; Tengfei Zhang; Jun Yao; Li Zhou; Yaxue Zeng; Hong Li; et al.

  Regulation of cellular metabolism by protein lysine acetylation

  Science. 2010;327(5968):1000-1004.
  291

• 36.

  2009

  Sarah Jackson; Yue Xiong

  CRL4s: the CUL4-RING E3 ubiquitin ligases

  Trends in Biochemical Sciences. 2009;34(11):562-570.
  74

• 37.

  2009

  Wei Yu; Yan Lin; Jun Yao; Wei Huang; Qunying Lei; Yue Xiong; Shimin Zhao; Kun-Liang Guan

  Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals

  Journal of Biological Chemistry. 2009;284(20):13669-13675.
  14

• 38.

  2009

  Heng Zhang; Chen-Ying Liu; Zheng-Yu Zha; Bin Zhao; Jun Yao; Shimin Zhao; Yue Xiong; Qun-Ying Lei; Kun-Liang Guan

  TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

  Journal of Biological Chemistry. 2009;284(20):13355-13362.
  56

• 39.

  2009

  Xin-Hai Pei; Feng Bai; Matthew D. Smith; Jerry Usary; Cheng Fan; Sung-Yun Pai; I-Cheng Ho; Charles M. Perou; Yue Xiong

  CDK Inhibitor p18^INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis

  Cancer Cell. 2009;15(5):389-401.
  28

• 40.

  2009

  Shimin Zhao; Yan Lin; Wei Xu; Wenqing Jiang; Zhengyu Zhai; Pu Wang; Wei Yu; Zhiqiang Li; Lingling Gong; Yingjie Peng; et al.

  Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α

  Science. 2009;324(5924):261-265.
  313

• 41.

  2009

  Yojiro Kotake; Zeng Yaxue; Yue Xiong

  DDB1-CUL4 and MLL1 mediate oncogene-lnduced p16 ^INK4aactivation

  Cancer Research. 2009;69(5):1809-1814.
  22

• 42.

  2009

  Sarah Jackson; Yue Xiong

  Targeting protein ubiquitylation: DDB1 takes its RING off

  Nature Cell Biology. 2009;11(4):379-381.
  3

• 43.

  2008

  Nick Van Buuren; Brianne Couturier; Yue Xiong; Michele Barry

  Ectromelia virus encodes a novel family of F-box proteins that interact with the SCF complex

  Journal of Virology. 2008;82(20):9917-9927.
  18

• 44.

  2008

  Chad M. McCall; Paula L. Miliani De Marval; Paul D. Chastain II; Sarah C. Jackson; Yizhou J. He; Yojiro Kotake; Jeanette Gowen Cook; Yue Xiong

  Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development

  Molecular and Cellular Biology. 2008;28(18):5621-5633.
  21

• 45.

  2008

  Yu Zhang; Suhua Feng; Fangfang Chen; Haodong Chen; Jia Wang; Chad McCall; Yue Xiong; Wang Deng Xing

  Arabidopsis DDB1-CUL4 associated factor1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes

  Plant Cell. 2008;20(6):1437-1455.
  34

• 46.

  2008

  Brianne A. Wilton; Stephanie Campbell; Nicholas Van Buuren; Robyn Garneau; Manabu Furukawa; Yue Xiong; Michele Barry

  Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases

  Virology. 2008;374(1):82-99.
  15

• 47.

  2008

  Jian Hu; Sima Zacharek; Yizhou Joseph He; Hyun Lee; Stuart Shumway; Robert J. Duronio; Yue Xiong

  WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase

  Genes and Development. 2008;22(7):866-871.
  46

• 48.

  2008

  Qun-Ying Lei; Heng Zhang; Bin Zhao; Zheng-Yu Zha; Feng Bai; Xin-Hai Pei; Shimin Zhao; Yue Xiong; Kun-Liang Guan

  TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

  Molecular and Cellular Biology. 2008;28(7):2426-2436.
  131

• 49.

  2008

  Jae-Hoon Lee; William Terzaghi; Giuliana Gusmaroli; Jean-Benoit F. Charron; Hye-Jin Yoon; Haodong Chen; Yizhou Joseph He; Yue Xiong; Xing Wang Deng

  Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases

  Plant Cell. 2008;20(1):152-167.
  68

• 50.

  2007

  Matthew R. Ramsey; Janakiraman Krishnamurthy; Xin-Hai Pei; Chad Torrice; Weili Lin; Daniel R. Carrasco; Keith L. Ligon; Yue Xiong; Norman E. Sharpless

  Expression of p16^Ink4a compensates for p18^Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues

  Cancer Research. 2007;67(10):4732-4741.
  23

• 51.

  2007

  Xin-Hai Pei; Feng Bai; Matthew D. Smith; Yue Xiong

  p18^Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers

  Cancer Research. 2007;67(7):3162-3170.
  28

• 52.

  2007

  Feng Bai; Xin-Hai Pei; Toru Nishikawa; Matthew D. Smith; Yue Xiong

  p18^Ink4c, but not p27^Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors

  Molecular and Cellular Biology. 2007;27(4):1495-1504.
  29

• 53.

  2007

  Yojiro Kotake; Ru Cao; Patrick Viatour; Julien Sage; Yi Zhang; Yue Xiong

  pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16^INK4a tumor suppressor gene

  Genes and Development. 2007;21(1):49-54.
  131

• 54.

  2006

  Yizhou Joseph He; Chad M. McCall; Jian Hu; Yaxue Zeng; Yue Xiong

  DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases

  Genes and Development. 2006;20(21):2949-2954.
  107

• 55.

  2006

  P. Andrews; Y.J. He; Y. Xiong

  Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function

  Oncogene. 2006;25(33):4534-4548.
  36

• 56.

  2006

  Stuart D. Shumway; Yue Xiong

  Twice Primed: Cyclin E Is Phosphorylated and Isomerized Before Being Ubiquitinated

  Molecular Cell. 2006;23(2):149-150.
  2

• 57.

  2006

  Feng Bai; Xin-Hai Pei; Pier Paolo Pandolfi; Yue Xiong

  p18^Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control

  Molecular and Cellular Biology. 2006;26(12):4564-4576.
  27

• 58.

  2006

  Hengbin Wang; Ling Zhai; Jun Xu; Heui-Yun Joo; Sarah Jackson; Hediye Erdjument-Bromage; Paul Tempst; Yue Xiong; Yi Zhang

  Histone H3 and H4 Ubiquitylation by the CUL4-DDB-ROC1 Ubiquitin Ligase Facilitates Cellular Response to DNA Damage

  Molecular Cell. 2006;22(3):383-394.
  187

• 59.

  2006

  Yue Xiong; Yojiro Kotake

  No exit strategy? No problem: APC inhibits β-catenin inside the nucleus

  Genes and Development. 2006;20(6):637-642.
  5

• 60.

  2006

  Jian Hu; Yue Xiong

  An evolutionarily conserved function of proliferating cell nuclear antigen for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage

  Journal of Biological Chemistry. 2006;281(7):3753-3756.
  66

• 61.

  2006

  Xiao-Ting Luo; Shu-Mei Li; Dao-Yuan Wen; Yue-Ling Xiong

  Structural characteristics of amniotic extracellular matrix prepared immediately and preserved for middle to long term

  Chinese Journal of Clinical Rehabilitation. 2006;10(1):79-81.
  3

• 62.

  2006

  Grigoriy I. Kovalev; Tamara D. Simon; V. McNeil Coffield; Yue Xiong; David S. Franklin; Lishan Su

  Control of thymocyte proliferation and thymus organ size by CDK inhibitors P18^INK4c and P27^KIP1

  Journal of Stem Cells. 2006;1(2):97-108.
  0

• 63.

  2005

  Sima J. Zacharek; Yue Xiong; Stuart D. Shumway

  Negative regulation of TSC1-TSC2 by mammalian D-type cyclins

  Cancer Research. 2005;65(24):11354-11360.
  19

• 64.

  2005

  Satyajit K. Karnik; Christina M. Hughes; Xueying Gu; Orit Rozenblatt-Rosen; Graeme W. McLean; Yue Xiong; Matthew Meyerson; Seung K. Kim

  Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27^Kip1 and p18^INK4c

  Proceedings of the National Academy of Sciences of the United States of America. 2005;102(41):14659-14664.
  153

• 65.

  2005

  Xin-Hai Pei; Yue Xiong

  Biochemical and cellular mechanisms of mammalian CDK inhibitors: A few unresolved issues

  Oncogene. 2005;24(17):2787-2795.
  81

• 66.

  2005

  Manabu Furukawa; Paul S Andrews; Yue Xiong

  Assays for RING family ubiquitin ligases.

  Methods in molecular biology (Clifton, N.J.). 2005;301:37-46.
  8

• 67.

  2005

  Chad M. McCall; Jian Hu; Yue Xiong

  Recruiting substrates to cullin 4-dependent ubiquitin ligases by DDB1

  Cell Cycle. 2005;4(1):27-29.
  9

• 68.

  2005

  Manabu Furukawa; Yue Xiong

  BTB protein keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase

  Molecular and Cellular Biology. 2005;25(1):162-171.
  203

• 69.

  2004

  Seth J. Goldenberg; Thomas C. Cascio; Stuart D. Shumway; Kenneth C. Garbutt; Jidong Liu; Yue Xiong; Ning Zheng

  Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases

  Cell. 2004;119(4):517-528.
  121

• 70.

  2004

  Jian Hu; Chad M. McCall; Tomohiko Ohta; Yue Xiong

  Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage

  Nature Cell Biology. 2004;6(10):1003-1009.
  173

• 71.

  2004

  Xin-Hai Pei; Feng Bai; Tateki Tsutsui; Hiroaki Kiyokawa; Yue Xiong

  Genetic evidence for functional dependency of p18^Ink4c on Cdk4

  Molecular and Cellular Biology. 2004;24(15):6653-6664.
  23

• 72.

  2004

  Suhua Feng; Yunping Shen; James A. Sullivan; Vicente Rubio; Yue Xiong; Tai-Ping Sun; Xing Wang Deng

  Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein

  Plant Cell. 2004;16(7):1870-1882.
  64

• 73.

  2003

  Yanping Zhang; Gabrielle White Wolf; Krishna Bhat; Aiwen Jin; Theresa Allio; William A. Burkhart; Yue Xiong

  Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway

  Molecular and Cellular Biology. 2003;23(23):8902-8912.
  235

• 74.

  2003

  Manabu Furukawa; Yizhou Joseph He; Christoph Borchers; Yue Xiong

  Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases

  Nature Cell Biology. 2003;5(11):1001-1007.
  176

• 75.

  2003

  Eric D. Tang; Cun-Yu Wang; Yue Xiong; Kun-Liang Guan

  A role for NF-κB essential modifier/IκB kinase-γ (NEMO/IKKγ) ubiquitination in the activation of the IκB kinase complex by tumor necrosis factor-α

  Journal of Biological Chemistry. 2003;278(39):37297-37305.
  135

• 76.

  2003

  Jennifer J. Michel; Joseph F. McCarville; Yue Xiong

  A role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression

  Journal of Biological Chemistry. 2003;278(25):22828-22837.
  30

• 77.

  2003

  Tom Luedde; Maria E. Rodriguez; Frank Tacke; Yue Xiong; David A. Brenner; Christian Trautwein

  p18(INK4c) collaborates with other CDK-inhibitory proteins in the regenerating liver

  Hepatology. 2003;37(4):833-841.
  15

• 78.

  2003

  Feng Bai; Xin-Hai Pei; Virginia L. Godfrey; Yue Xiong

  Haploinsufficiency of p18^INK4c sensitizes mice to carcinogen-induced tumorigenesis

  Molecular and Cellular Biology. 2003;23(4):1269-1277.
  66

• 79.

  2003

  Stuart D. Shumway; Yong Li; Yue Xiong

  14-3-3β binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin

  Journal of Biological Chemistry. 2003;278(4):2089-2092.
  52

• 80.

  2002

  Jidong Liu; Manabu Furukawa; Tomohiro Matsumoto; Yue Xiong

  NEDD8 modification of CUL1 dissociates p120^CAND1, an inhibitor of CUL1-SKP1 binding and SCF ligases

  Molecular Cell. 2002;10(6):1511-1518.
  159

• 81.

  2002

  Michelle R. Tourigny; Josie Ursini-Siegel; Hayyoung Lee; Kai-Michael Toellner; Adam F. Cunningham; David S. Franklin; Scott Ely; Meihong Chen; Xiao-Feng Qin; Yue Xiong; et al.

  CDK inhibitor p18^INK4c is required for the generation of functional plasma cells

  Immunity. 2002;17(2):179-189.
  60

• 82.

  2002

  Manabu Furukawa; Tomohiko Ohta; Yue Xiong

  Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins

  Journal of Biological Chemistry. 2002;277(18):15758-15765.
  60

• 83.

  2002

  Wendell G. Yarbrough; Mika Bessho; Adam Zanation; John E. Bisi; Yue Xiong

  Human tumor suppressor ARF impedes S-phase progression independent of p53

  Cancer Research. 2002;62(4):1171-1177.
  47

• 84.

  2001

  G.I. Kovalev; D.S. Franklin; V.M. Coffield; Y. Xiong; L. Su

  An important role of CDK inhibitor p18^INK4c in modulating antigen receptor-mediated T cell proliferation

  Journal of Immunology. 2001;167(6):3285-3292.
  39

• 85.

  2001

  Y. Zhang; Y. Xiong

  A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation

  Science. 2001;292(5523):1910-1915.
  233

• 86.

  2001

  Tomohiko Ohta; Yue Xiong

  Phosphorylation- and SKP1-independent in Vitro ubiquitination of E2F1 by multiple ROC-cullin ligases

  Cancer Research. 2001;61(4):1347-1353.
  32

• 87.

  2001

  Peiwen Yu; Betty Huang; Mary Shen; Clorinda Lau; Eva Chan; Jennifer Michel; Yue Xiong; Donald G. Payan; Ying Luo

  p15^PAF, a novel PCNA associated factor with increased expression in tumor tissues

  Oncogene. 2001;20(4):484-489.
  28

• 88.

  2001

  Y. Zhang; Y. Xiong

  Control of p53 ubiquitination and nuclear export by MDM2 and ARF

  Cell Growth and Differentiation. 2001;12(4):175-186.
  117

• 89.

  2000

  M. Furukawa; Y. Zhang; J. McCarville; T. Ohta; Y. Xiong

  The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1

  Molecular and Cellular Biology. 2000;20(21):8185-8197.
  90

• 90.

  2000

  D.S. Franklin; V.L. Godfrey; D.A. O'Brien; C. Deng; Y. Xiong

  Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity

  Molecular and Cellular Biology. 2000;20(16):6147-6158.
  182

• 91.

  1999

  Tomohiko Ohta; Jennifer J. Michel; Yue Xiong

  Association with cullin partners protects ROC proteins from proteasome-dependent degradation

  Oncogene. 1999;18(48):6758-6766.
  32

• 92.

  1999

  Tomohiko Ohta; Jennifer J. Michel; Arndt J. Schottelius; Yue Xiong

  ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

  Molecular Cell. 1999;3(4):535-541.
  309

• 93.

  1999

  Serge Y. Fuchs; Angus Chen; Yue Xiong; Zhen-Qiang Pan; Ze'ev Ronai

  HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IκB and β-catenin

  Oncogene. 1999;18(12):2039-2046.
  115

• 94.

  1999

  Seong J. Noh; Yan Li; Yue Xiong; Kun-Liang Guan

  Identification of functional elements of p18(INK4C) essential for binding and inhibition of cyclin-dependent kinase (CDK) 4 and CDK6

  Cancer Research. 1999;59(3):558-564.
  14

• 95.

  1999

  Yanping Zhang; Yue Xiong

  Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

  Molecular Cell. 1999;3(5):579-591.
  294

• 96.

  1998

  Maimoona Zariwala; Jidong Liu; Yue Xiong

  Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins

  Oncogene. 1998;17(21):2787-2798.
  57

• 97.

  1998

  David S. Franklin; Virginia L. Godfrey; Hayyoung Lee; Grigoriy I. Kovalev; Robert Schoonhoven; Selina Chen-Kiang; Lishan Su; Yue Xiong

  CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

  Genes and Development. 1998;12(18):2899-2911.
  248

• 98.

  1998

  Dawn E. Phelps; Yue Xiong

  Regulation of cyclin-dependent kinase 4 during adipogenesis involves switching of cyclin D subunits and concurrent binding of p18(INK4c) and p27(Kip11)

  Cell Growth and Differentiation. 1998;9(8):595-610.
  38

• 99.

  1998

  Josée Laliberté; Ann Yee; Yue Xiong; Beverly S. Mitchell

  Effects of guanine nucleotide depletion on cell cycle progression in human T lymphocytes

  Blood. 1998;91(8):2896-2904.
  61

• 100.

  1998

  Dawn E. Phelps; Kuang-Ming Hsiao; Yan Li; Nanpin Hu; David S. Franklin; Eva Westphal; Eva Y.-H. P. Lee; Yue Xiong

  Coupled transcriptional and translational control of cyclin-dependent kinase inhibitor p18(INK4c) expression during myogenesis

  Molecular and Cellular Biology. 1998;18(4):2334-2343.
  67

• 101.

  1998

  Yanping Zhang; Yue Xiong; Wendell G. Yarbrough

  ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

  Cell. 1998;92(6):725-734.
  1046

• 102.

  1998

  Tomohiko Ohta; Kazuki Okamoto; Fumihide Isohashi; Kiyotaka Shibata; Mamoru Fukuda; Susumu Yamaguchi; Yue Xiong

  T-loop deletion of CDC2 from breast cancer tissues eliminates binding to cyclin B1 and cyclin-dependent kinase inhibitor p21

  Cancer Research. 1998;58(6):1095-1098.
  9

• 103.

  1998

  H. Watanabe; Z.-Q. Pan; N. Schreiber-Agus; R.A. DePinho; J. Hurwitz; Y. Xiong

  Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57(KIP2) requires binding to proliferating cell nuclear antigen

  Proceedings of the National Academy of Sciences of the United States of America. 1998;95(4):1392-1397.
  112

• 104.

  1998

  Jennifer J. Michel; Yue Xiong

  Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A

  Cell Growth and Differentiation. 1998;9(6):435-449.
  99

• 105.

  1998

  S.J. Noh; Y. Lj; Y. Xiong; K.L. Guan

  Identification of essential functional elements of pls!nk4c

  FASEB Journal. 1998;12(8):A1327.
  0

• 106.

  1997

  Hideki Tahara; Alison P. Smith; Randall D. Gaz; Maimoona Zariwala; Yue Xiong; Andrew Arnold

  Parathyroid tumor suppressor on 1p: Analysis of the p18 cyclin-dependent kinase inhibitor gene as a candidate

  Journal of Bone and Mineral Research. 1997;12(9):1330-1334.
  23

• 107.

  1997

  Dawn E. Phelps; Yue Xiong

  Assay for activity of mammalian cyclin D-dependent kinases CDK4 and CDK6

  Methods in Enzymology. 1997;283:194-205.
  28

• 108.

  1997

  Leslie Morse; Dongquan Chen; David Franklin; Yue Xiong; Selina Chen-Kiang

  Induction of cell cycle arrest and β cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6

  Immunity. 1997;6(1):47-56.
  110

• 109.

  1996

  David A. Alcorta; Yue Xiong; Dawn Phelps; Greg Hannon; David Beach; J. Carl Barrett

  Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

  Proceedings of the National Academy of Sciences of the United States of America. 1996;93(24):13742-13747.
  519

• 110.

  1996

  David S. Franklin; Yue Xiong

  Induction of p18(INK4c) and its predominant association with CDK4 and CDK6 during myogenic differentiation

  Molecular Biology of the Cell. 1996;7(10):1587-1599.
  89

• 111.

  1996

  Dale R. Mayrose; Michael A. Nichols; Yue Xiong; Hengming Ke

  Purification and crystallization of cyclin-dependent kinase inhibitor p21

  Protein Science. 1996;5(9):1928-1930.
  4

• 112.

  1996

  Yue Xiong

  Why are there so many CDK inhibitors?

  Biochimica et Biophysica Acta - Reviews on Cancer. 1996;1288(1):O1-O5.
  41

• 113.

  1996

  Marek R. Rusin; Aikou Okamoto; Mieczyslaw Chorazy; Kazimierz Czyzewski; Jolanta Harasim; Elisa A. Spillare; Koichi Hagiwara; S. Perwez Hussain; Yue Xiong; Douglas J. Demetrick; et al.

  Intragenic mutations of the p16^INK4, p15^INK4B and p18 GENES in primary non-small-cell lung cancers

  International Journal of Cancer. 1996;65(6):734-739.
  54

• 114.

  1996

  Hua Wu; Michael Wade; Leonard Krall; Joe Grisham; Yue Xiong; Terry Van Dyke

  Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development, and regeneration

  Genes and Development. 1996;10(3):245-260.
  177

• 115.

  1996

  A. Yee; L. Wu; L. Liu; R. Kobayashi; Y. Xiong; F.L. Hall

  Biochemical characterization of the human cyclin-dependent protein kinase activating kinase. Identification of p35 as a novel regulatory subunit

  Journal of Biological Chemistry. 1996;271(1):471-477.
  9

• 116.

  1996

  Maimoona Zariwala; Yue Xiong

  Lack of mutation in the cyclin-dependent kinase inhibitor, p19(INK4d), in tumor-derived cell lines and primary tumors

  Oncogene. 1996;13(9):2033-2038.
  24

• 117.

  1996

  Maimoona Zariwala; Edison Liu; Yue Xiong

  Mutational analysis of the p16 family cyclin-dependent kinase inhibitors p15 ^INK4b and p18^INK4c in tumor-derived cell lines and primary tumors

  Oncogene. 1996;12(2):451-455.
  37

• 118.

  1996

  Yue Xiong; Dhandapani Kuppuswamy; Yan Li; Elizabeth M. Livanos; Mary Hixon; Alicia White; David Beach; Thea D. Tlsty

  Alteration of cell cycle kinase complexes in human papillomavirus E6- and E7-expressing fibroblasts precedes neoplastic transformation

  Journal of Virology. 1996;70(2):999-1008.
  80

• 119.

  1996

  Cynthia A. Afshari; Michael A. Nichols; Yue Xiong; Maria Mudryj

  A role for a p21-E2F interaction during senescence arrest of normal human fibroblasts

  Cell Growth and Differentiation. 1996;7(8):979-988.
  40

• 120.

  1996

  Kun-Liang Guan; Christopher W. Jenkins; Yan Li; Christine L. O'Keefe; Seong Noh; Xiaoyu Wu; Maimoona Zariwala; A. Gregory Matera; Yue Xiong

  Isolation and characterization of p19^INK4d, a p16-related inhibitor specific to CDK6 and CDK4

  Molecular Biology of the Cell. 1996;7(1):57-70.
  93

• 121.

  1996

  Akihiko Gemma; Seiichi Takenoshita; Koichi Hagiwara; Aikou Okamoto; Elisa A. Spillare; Mary G. Mcmemamin; S. Perwez Hussain; Kathleen Forrester; Maimoona Zariwala; Yue Xiong; et al.

  Molecular analysis of the cyclin-dependent kinase inhibitor genes p15(INK4b/MTS2), p16(INK4/MTS1), p18 and p19 in human cancer cell lines

  International Journal of Cancer. 1996;68(5):605-611.
  43

• 122.

  1995

  Jian-Ming Li; Michael A. Nichols; Subhashini Chandrasekharan; Yue Xiong; Xiao-Fan Wang

  Transforming growth factor β activates the promoter of cyclin-dependent kinase inhibitor p15^INK4B through an Sp1 consensus site

  Journal of Biological Chemistry. 1995;270(45):26750-26753.
  204

• 123.

  1995

  Michael B. Datto; Yan Li; Joanne F. Panus; David J. Howe; Yue Xiong; Xiao-Fan Wang

  Transforming growth factor β induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

  Proceedings of the National Academy of Sciences of the United States of America. 1995;92(12):5545-5549.
  678

• 124.

  1995

  Aikou Okamoto; S. Perwez Hussain; Koichi Hagiwara; Elisa A. Spillare; Marek R. Rusin; Douglas J. Demetrick; Manuel Serrano; Gregory J. Hannon; Masayuki Shiseki; Maimoona Zariwala; et al.

  Mutations in the p16^INK4/MTS1/CDKN2, p15^INK4B/MTS2, and p18 genes in primary and metastatic lung cancer

  Cancer Research. 1995;55(7):1448-1451.
  240

• 125.

  1995

  O. Aprelikova; Y. Xiong; E.T. Liu

  Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase

  Journal of Biological Chemistry. 1995;270(31):18195-18197.
  160

• 126.

  1995

  D.J. Demetrick; S. Matsumoto; G.J. Hannon; K. Okamoto; Y. Xiong; H. Zhang; D.H. Beach

  Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3)

  Cytogenetics and Cell Genetics. 1995;69(3-4):190-192.
  39

• 127.

  1995

  P.R.K. Koduru; M. Zariwala; M. Soni; J.Z. Gong; Y. Xiong; J.D. Broome

  Deletion of cyclin-dependent kinase 4 inhibitor genes P15 and P16 in non- Hodgkin's lymphoma

  Blood. 1995;86(8):2900-2905.
  63

• 128.

  1995

  Yi Sun; Allan Hildesheim; Hua Li; Yan Li; Jen-Yang Chen; Yu-Juen Cheng; Richard B. Hayes; Nathaniel Rothman; Wen-Fang Bi; Ya Cao; et al.

  No point mutation but a Codon 31^ser→arg polymorphism of the WAF-1/CIP-1/p21 tumor suppressor gene in nasopharyngeal carcinoma (NPC): The polymorphism distinguishes caucasians from Chinese

  Cancer Epidemiology Biomarkers and Prevention. 1995;4(3):261-267.
  42

• 129.

  1995

  A. Yee; M.A. Nichols; L. Wu; F.L. Hall; R. Kobayashi; Y. Xiong

  Molecular cloning of CDK7-associated human MAT1, a cyclin-dependent kinase-activating kinase (CAK) assembly factor

  Cancer Research. 1995;55(24):6058-6062.
  31

• 130.

  1994

  Kun-Liang Guan; Christopher W. Jenkins; Yan Li; Michael A. Nichols; Xiaoyu Wu; Christine L. O'Keefe; A. Gregory Matera; Yue Xiong

  Growth suppression by p18, a p16^INK4/MTS1- and p14^INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

  Genes and Development. 1994;8(24):X-2952.
  47

• 131.

  1994

  Yan Li; Michael A. Nichols; Jerry W. Shay; Yue Xiong

  Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb

  Cancer Research. 1994;54(23):6078-6082.
  264

• 132.

  1994

  Yan Li; Christopher W. Jenkins; Michael A. Nichols; Yue Xiong

  Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21

  Oncogene. 1994;9(8):2261-2268.
  288

• 133.

  1994

  Angelika Philipp; Andreas Schneider; Imre Väsrik; Kerstin Finke; Yue Xiong; David Beach; Kari Alitalo; Martin Eilers

  Repression of cyclin D1: A novel function of MYC

  Molecular and Cellular Biology. 1994;14(6):4032-4043.
  195

• 134.

  1994

  K.-L. Guan; C.W. Jenkins; Y. Li; M.A. Nichols; X. Wu; C.L. O'Keefe; A.G. Matera; Y. Xiong

  Growth suppression by p18, a p16(INK4/MTS1)- and p14(INK4B/MTS2)-related CDK6 inhibitor, correlates with wild-type pRb function

  Genes and Development. 1994;8(24):2939-2952.
  546

• 135.

  1993

  Y. Xiong; W.D. Burke; T.H. Eickbush

  Pao, a highly divergent retrotransposable element from Bombyx mori containing long terminal repeats with tandem copies of the putative R region

  Nucleic Acids Research. 1993;21(9):2117-2123.
  35

• 136.

  1993

  Y. Xiong; H. Zhang; D. Beach

  Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

  Genes and Development. 1993;7(8):1572-1583.
  330

• 137.

  1993

  H. Zhang; Y. Xiong; D. Beach

  Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

  Molecular Biology of the Cell. 1993;4(9):897-906.
  246

• 138.

  1993

  W.D. Burke; D.G. Eickbush; Y. Xiong; J. Jakubczak; T.H. Eickbush

  Sequence relationship of retrotransposable elements R1 and R2 within and between divergent insect species

  Molecular Biology and Evolution. 1993;10(1):163-185.
  53

• 139.

  1993

  Y. Xiong; G.J. Hannon; H. Zhang; D. Casso; R. Kobayashi; D. Beach

  p21 is a universal inhibitor of cyclin kinases

  Nature. 1993;366(6456):701-704.
  2271

• 140.

  1993

  Y. Xiong; T.H. Eickbush

  Dong, a non-long terminal repeat (non-LTR) retrotransposable element from Bombyx mori

  Nucleic Acids Research. 1993;21(5):1318.
  19

• 141.

  1992

  Y. Xiong; H. Zhang; D. Beach

  D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

  Cell. 1992;71(3):505-514.
  590

• 142.

  1992

  Y. Xiong; J. Menninger; D. Beach; D.C. Ward

  Molecular cloning and chromosomal mapping of CCND genes encoding human D- type cyclins

  Genomics. 1992;13(3):575-584.
  110

• 143.

  1992

  K.-A. Won; Y. Xiong; D. Beach; M.Z. Gilman

  Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts

  Proceedings of the National Academy of Sciences of the United States of America. 1992;89(20):9910-9914.
  165

• 144.

  1991

  Y. Xiong; T. Connolly; B. Futcher; D. Beach

  Human D-type cyclin

  Cell. 1991;65(4):691-699.
  334

• 145.

  1991

  Yue Xiong; David Beach

  Population explosion in the cyclin family

  Current Biology. 1991;1(6):362-364.
  8

• 146.

  1990

  Y. Xiong; T.H. Eickbush

  Origin and evolution of retroelements based upon their reverse transcriptase sequences

  EMBO Journal. 1990;9(10):3353-3362.
  710

• 147.

  1990

  J.L. Jakubczak; Y. Xiong; T.H. Eickbush

  Type I (R1) and type II (R2) ribosomal DNA insertions of Drosophila melanogaster are retrotransposable elements closely related to those of Bombyx mori

  Journal of Molecular Biology. 1990;212(1):37-52.
  69

• 148.

  1988

  Yue Xiong; Thomas H. Eickbush

  Functional expression of a sequence-specific endonuclease encoded by the retrotransposon R2Bm

  Cell. 1988;55(2):235-246.
  57

• 149.

  1988

  Y. Xiong; T.H. Eickbush

  Similarity of reverse transcriptase-like sequences of viruses, transposable elements, and mitochondrial introns

  Molecular Biology and Evolution. 1988;5(6):675-690.
  76

• 150.

  1988

  Y. Xiong; W.D. Burke; J.L. Jakubczak; T.H. Eickbush

  Ribosomal DNA insertion elements R1Bm and R2Bm can transpose in a sequence specific manner to locations outside the 28S genes

  Nucleic Acids Research. 1988;16(22):10561-10573.
  21

• 151.

  1988

  Y. Xiong; T.H. Eickbush

  The site-specific ribosomal DNA insertion element R1Bm belongs to a class of non-long-terminal-repeat retrotransposons.

  Molecular and Cellular Biology. 1988;8(1):114-123.
  50

• 152.

  1988

  Y. Xiong; B. Sakaguchi; T.H. Eickbush

  Gene conversions can generate sequence variants in the late chorion multigene families of Bombyx mori

  Genetics. 1988;120(1):221-231.
  10