Psychiatry

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Grant Detail

This is a chronological listing of grants held by this department, with the most recent listed first. New grants appear in this list weekly and contribute related to the department's Research Profile. The source of grants for this application comes directly from your institution.



Medication Use, Comorbidity and Outcomes in Aging Populations

Til Stürmer

6/1/2008 - 3/31/2011

Sponsoring Organization:Industry Sponsor
Awarding Organization Is:University of North Carolina at Chapel Hill
Funding:$ 30,355.00

Til Hans Robert Stürmer (Lead Principal Investigator)

Abstract

The characterization of the impact of comorbid conditions on use of preventive drug therapies in older people, the quantification of the magnitude of clustering in use of preventive medications among patients of the same provider, the question of optimal referent groups for new user designs in pharmacoepidemology, and the assessment of longitudinal patterns in use of preventive therapies as people approach death. Specifically, the project will address possibilities to quantify unmeasured confounding by evaluating the time course of apparent mortality risk reduction associated with preventive drug use after stopping of the corresponding drug under the assumption that unmeasured confounding will be strongest right after stopping and then will gradually level off as those who were close to death when stopping have died and therefore are not part of the at risk group anymore.