This is a chronological listing of grants held by this department, with the most recent listed first. New grants appear in this list weekly and contribute related to the department's Research Profile. The source of grants for this application comes directly from your institution.
Prevention and treatment of radiation-induced enteropathy by an oral absorbent,
Ryan Sartor; Bo Liu; Chris Packey10/1/2009 - 9/30/2011
|Sponsoring Organization:||Industry Sponsor|
|Awarding Organization Is:||University of North Carolina at Chapel Hill|
Ryan Balfour Sartor (Lead Principal Investigator)
Enteric commensal bacteria have been implicated in the pathogenesis of ionizing radiation-induced intestinal injury by studies in germ-free and antibiotic-treated mice by Dr. Sartor’s laboratory. The hypothesis of this study is that binding and inactivating bacterial products and inflammatory mediators by orally delivered AST-120, a novel, high capacity oral absorbent, can prevent and treat total body radiation-induced enteropathy and its systemic consequences.