Toxicology Curriculum

University of North Carolina at Chapel Hill, School of Medicine

Research Profile

• 

  Sesquiterpenes

  
• 

  Nucleic Acids

  
• 

  Liver

  
• 

  Primaquine

  
• 

  Organoplatinum Compounds

  
• 

  Chloroquine

  
• 

  IMP Dehydrogenase

  
• 

  Antineoplastic Agents, Phytogenic

  
• 

  Rats, Inbred F344

  
• 

  Aminoquinolines

  

Publications

• 1.

  1995

  D.Charles Thompson; Steven D. Wyrick; David J. Holbrook; Stephen G. Chaney

  HPLC and ³¹P NMR characterization of the reaction between antitumor platinum agents and the phosphorothioate chemoprotective agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721)

  Biochemical Pharmacology. 1995;50(9):1413-1419.

• 2.

  1995

  D.C. Thompson; S.D. Wyrick; D.J. Holbrook; S.G. Chaney

  Effect of the chemoprotective agent WR-2721 on disposition and biotransformations of ormaplatin in the Fischer 344 rat bearing a fibrosarcoma

  Cancer Research. 1995;55(13):2837-2846.

• 3.

  1995

  D.C. Thompson; S.D. Wyrick; D.J. Holbrook; S.G. Chaney

  Effects of anesthetics on ormaplatin biotransformations in the Fischer 344 rat

  Cancer Investigation. 1995;13(5):555-557.

Journals

•  
  Publications
• Biochemical Pharmacology
  6
• Molecular Pharmacology
  4
• Environmental Health Perspectives
  3
• Experimental Cell Research
  3
• Fundamental and Applied Toxicology
  2

Institutional Network

• Internal
  Shared Pub.
• Biochemistry and Biophysics
  18
• Pharmacy
  10

• External
  Shared Pub.
• University of North Carolina School of Medicine
  12
• GlaxoSmithKline
  2
• Division of Medicinal Chemistry
  1
• Curriculum in Genetics
  1