Translational and Clinical Sciences Institute (TraCS)

University of North Carolina at Chapel Hill, School of Medicine

Research Profile

• 

  Metabolomics

  
• 

  Nuclear magnetic resonance

  
• 

  Glycosylation

  
• 

  Tissue culture

  
• 

  Magnetic Resonance Spectroscopy

  
• 

  Metabolites

  
• 

  Van der Waals forces

  
• 

  Tissue engineering

  
• 

  Stabilizers (agents)

  
• 

  Bioreactors

  

Publications

• 1.

  2012

  Hong-Hee Won; Suk Ran Kim; Oh Young Bang; Sang-Chol Lee; Wooseong Huh; Jae-Wook Ko; Hyung-Gun Kim; Howard L. McLeod; Thomas M. O'Connell; Jong-Won Kim; et al.

  Differentially expressed genes in human peripheral blood as potential markers for statin response

  Journal of Molecular Medicine. 2012;90(2):201-211.

• 2.

  2012

  Hirak Der-Torossian; Scott A. Asher; Jason H. Winnike; Ashley Wysong; Xiaoying Yin; Monte S. Willis; Thomas M.  O'Connell; Marion E. Couch

  Cancer cachexia's metabolic signature in a murine model confirms a distinct entity

  Metabolomics. 2012:1-10.

• 3.

  2011

  Dallas R. Donohoe; Nikhil Garge; Xinxin Zhang; Wei Sun; Thomas M. O'Connell; Maureen K. Bunger; Scott J. Bultman

  The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon

  Cell Metabolism. 2011;13(5):517-526.

Grants

• 1.

  Victoria Bae-Jump; Thomas O'Connell

  Cross-species Investigation of the Impact of Obesity on Ovarian Cancer Pathogenesis

  3/1/2011 - 4/30/2013

  Sponsor: Gynecologic Cancer Foundation

  Funding: $ 50,000.00

• 2.

  Richard Tidwell; Thomas O'Connell; Mary Paine; Paul Watkins; James Hall

  Assessment of potential etiologies for the delayed hepatic and renal toxicity of

  11/19/2009 - 6/15/2012

  Sponsor: Bill and Melinda Gates Foundation

  Funding: $ 1,798,331.00

• 3.

  James Swenberg; Marilie Gammon; Kathleen Gray; Amy Herring; William Kaufmann; Robert Millikan; Thomas O'Connell; Andrew Olshan; Melissa Troester

  UNC-CH Center for Environmental Health and Susceptibility

  2/1/2000 - 3/31/2010

  Sponsor: NIH National Institute of Environmental Health Sciences (NIEHS)

  Funding: $ 1,471,858.00

Journals

•  
  Publications
• Journal of Biomolecular NMR
  2
• Metabolomics
  2
• Clinical Pharmacology and Therapeutics
  2
• Toxicological Sciences
  2
• Toxicology and Applied Pharmacology
  1

Institutional Network

• Internal
  Shared Pub.
• Medicine
  6
• Pharmacy
  5
• Biomedical Engineering
  4
• Biostatistics
  2
• Genetics
  2

• External
  Shared Pub.
• National Institute of Environmental Health Sciences
  5
• University of North Carolina School of Medicine
  5
• University of California, Santa Barbara
  4
• Harvard Medical School
  2
• The Hamner Institutes for Health Sciences
  2
• Dana-Farber Cancer Institute
  2