Scopus Publication Detail
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Journal of Clinical Investigation. 1983;71(5):1410-1417.Abstract
The raised transepithelial electric potential difference (PD) across respiratory epithelia in cystic fibrosis (PD) across epithelia in cystic fibrosis (CF) has suggested an abnormality in ion permeation. We characterized this abnormality further by measuring in the nasal epithelia of CF and normal subjects the concentration-PD relationship and normal subjects the concentration-PD relationship for amiloride, an inhibitor of cell Na+ permeability, and PD responses to superfusion with solutions of different composition. Amiloride was more efficacious in the CF subjects but the ED
PMID: 6853720 PMCID: PMC437005
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