Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry
Su-Tang Lo; Amit Kumar; Jer-Tsong Hsieh; Xiankai Sun(Profiled Authors: Jer-Tsong Hsieh; Xiankai Sun)
Molecular Pharmaceutics. 2013;10(3):793-812.Abstract
Dendrimers are a class of structurally defined macromolecules featured with a central core, a low-density interior formed by repetitive branching units, and a high-density exterior terminated with surface functional groups. In contrast to their polymeric counterparts, dendrimers are nanosized and symmetrically shaped, which can be reproducibly synthesized on a large scale with monodispersity. These unique features have made dendrimers of increasing interest for drug delivery and other biomedical applications as nanoscaffold systems. Intended to address the potential use of dendrimers for the development of theranostic agents, which combines therapeutics and diagnostics in a single entity for personalized medicine, this review focuses on the reported methodologies of using dendrimer nanoscaffolds for targeted imaging and therapy of prostate cancer. Of particular interest, relevant chemistry strategies are discussed due to their important roles in the design and synthesis of diagnostic and therapeutic dendrimer-based nanoconjugates and potential theranostic agents, targeted or nontargeted. Given the developing status of nanoscaffolded theranostics, major challenges and potential hurdles are discussed along with the examples representing current advances. © 2013 American Chemical Society.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Jongdoo Lim; Abdellatif Chouai; Su-Tang Lo; Wei Liu; Xiankai Sun; Eric E. SimanekBioconjugate Chemistry. 2009;20(11):2154-2161.
Kristen Evaul; Rui Li; Mahboubeh Papari-Zareei; Richard J. Auchus; Nima SharifiEndocrinology. 2010;151(8):3514-3520.
Su-Tang Lo; Stephan Stern; Jeffrey D. Clogston; Jiwen Zheng; Pavan P. Adiseshaiah; Marina Dobrovolskaia; Jongdoo Lim; Anil K. Patri; Xiankai Sun; Eric E. SimanekMolecular Pharmaceutics. 2010;7(4):993-1006.
Appears in this Document