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Optically active allenes from an allylic substitution/isomerization sequence

Wenhan Zhang; Joseph M. Ready

(Profiled Author: Joseph M Ready)

ChemCatChem. 2013;5(12):3497-3498.


It takes two to trisubstitute: A two-step procedure involving enantioselective allylic alkylation followed by 1,3 hydrogen shift enables the catalytic asymmetric synthesis of trisubstituted allenes. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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