Gerold Bepler

Grant Detail

The grant details show the name of the PI, active dates of the project, the funding institute and the abstract of the grant. This abstract is what is used to create the Fingerprint of the grant. The source of grants for this application is NIH ExPORTER, so only NIH grants are included. More information is available at http://projectreporter.nih.gov/ExPORTER/default.aspx.

CANCER CENTER SUPPORT GRANT

8 August 1997 - 30 November 2015
NATIONAL CANCER INSTITUTE
Total Funding: $ 5,758,873

357 Resulting Publications

• 1.

  2013

  Bavneet Benipal; Lawrence H Lash

  Modulation of mitochondrial glutathione status and cellular energetics in primary cultures of proximal tubular cells from remnant kidney of uninephrectomized rats.

  Biochemical pharmacology 2013;85(9):1379-88.

• 2.

  2013

  Margaret R Spitz; Christopher I Amos; Susan Land; Xifeng Wu; Qiong Dong; Angela S Wenzlaff; Ann G Schwartz

  Role of selected genetic variants in lung cancer risk in African Americans.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(4):391-7.

• 3.

  2013

  M K Herroon; E Rajagurubandara; D L Rudy; A Chalasani; A L Hardaway; I Podgorski

  Macrophage cathepsin K promotes prostate tumor progression in bone.

  Oncogene 2013;32(12):1580-93.

• 4.

  2013

  Hitchintan Kaur; Shihong Mao; Seema Shah; David H Gorski; Stephen A Krawetz; Bonnie F Sloane; Raymond R Mattingly

  Next-generation sequencing: a powerful tool for the discovery of molecular markers in breast ductal carcinoma in situ.

  Expert review of molecular diagnostics 2013;13(2):151-65.

• 5.

  2013

  Douglas W Strand; David J DeGraff; Ming Jiang; Mansoureh Sameni; Omar E Franco; Harold D Love; William J Hayward; Opal Lin-Tsai; Anne Y Wang; Justin M M Cates; et al.

  Deficiency in metabolic regulators PPARγ and PTEN cooperates to drive keratinizing squamous metaplasia in novel models of human tissue regeneration.

  The American journal of pathology 2013;182(2):449-59.

• 6.

  2013

  Manjeera Paladugu; Archana Thakur; Lawrence G Lum; Sandeep Mittal; Prahlad Parajuli

  Generation and immunologic functions of Th17 cells in malignant gliomas.

  Cancer immunology, immunotherapy : CII 2013;62(1):75-86.

• 7.

  2013

  Archana Thakur; Dana Schalk; Elyse Tomaszewski; Sri Vidya Kondadasula; Hiroshi Yano; Fazlul H Sarkar; Lawrence G Lum

  Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE2 dependent pathway.

  Journal of translational medicine 2013;11():35.

• 8.

  2013

  Ian M Zitron; Archana Thakur; Oxana Norkina; Geoffrey R Barger; Lawrence G Lum; Sandeep Mittal

  Targeting and killing of glioblastoma with activated T cells armed with bispecific antibodies.

  BMC cancer 2013;13():83.

• 9.

  2012

  Wei Chen; Debashis Ghosh; Trivellore E Raghunathan; Maxim Norkin; Daniel J Sargent; Gerold Bepler

  On Bayesian methods of exploring qualitative interactions for targeted treatment.

  Statistics in medicine 2012;31(28):3693-707.

• 10.

  2012

  Stefanie R Mullins; Mansoureth Sameni; Galia Blum; Matthew Bogyo; Bonnie F Sloane; Kamiar Moin

  Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins.

  Biological chemistry 2012;393(12):1405-16.

• 11.

  2012

  Michael S Simon; Rowan T Chlebowski; Jean Wactawski-Wende; Karen C Johnson; Andrew Muskovitz; Ikuko Kato; Alicia Young; F Allan Hubbell; Ross L Prentice

  Estrogen plus progestin and colorectal cancer incidence and mortality.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(32):3983-90.

• 12.

  2012

  Deepa Jagtap; Carol A Rosenberg; Lisa W Martin; Mary Pettinger; Janardan Khandekar; Dorothy Lane; Ira Ockene; Michael S Simon

  Prospective analysis of association between use of statins and melanoma risk in the Women's Health Initiative.

  Cancer 2012;118(20):5124-31.

• 13.

  2012

  Courtney R Giordano; Kelly L Mueller; Laura J Terlecky; Kendra A Krentz; Aliccia Bollig-Fischer; Stanley R Terlecky; Julie L Boerner

  A targeted enzyme approach to sensitization of tyrosine kinase inhibitor-resistant breast cancer cells.

  Experimental cell research 2012;318(16):2014-21.

• 14.

  2012

  Darren R Brenner; Paolo Boffetta; Eric J Duell; Heike Bickeböller; Albert Rosenberger; Valerie McCormack; Joshua E Muscat; Ping Yang; H-Erich Wichmann; Irene Brueske-Hohlfeld; et al.

  Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium.

  American journal of epidemiology 2012;176(7):573-85.

• 15.

  2012

  Michele L Coté; Mei Liu; Stefano Bonassi; Monica Neri; Ann G Schwartz; David C Christiani; Margaret R Spitz; Joshua E Muscat; Gad Rennert; Katja K Aben; et al.

  Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium.

  European journal of cancer (Oxford, England : 1990) 2012;48(13):1957-68.

• 16.

  2012

  Stephen G Henry; Susan Eggly

  How much time do low-income patients and primary care physicians actually spend discussing pain? A direct observation study.

  Journal of general internal medicine 2012;27(7):787-93.

• 17.

  2012

  Hyun J Bang; Peter J Littrup; Dylan J Goodrich; Brandt P Currier; Hussein D Aoun; Lance K Heilbrun; Ulka Vaishampayan; Barbara Adam; Allen C Goodman

  Percutaneous cryoablation of metastatic renal cell carcinoma for local tumor control: feasibility, outcomes, and estimated cost-effectiveness for palliation.

  Journal of vascular and interventional radiology : JVIR 2012;23(6):770-7.

• 18.

  2012

  Sagar Dandawate; Linford Williams; Nirmal Joshee; Agnes M Rimando; Sandeep Mittal; Archana Thakur; Lawrence G Lum; Prahlad Parajuli

  Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-β1 activity.

  Cancer immunology, immunotherapy : CII 2012;61(5):701-11.

• 19.

  2012

  Ann G Schwartz

  Genetic epidemiology of cigarette smoke-induced lung disease.

  Proceedings of the American Thoracic Society 2012;9(2):22-6.

• 20.

  2012

  Yun-Hee Lee; Anelia P Petkova; Emilio P Mottillo; James G Granneman

  In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding.

  Cell metabolism 2012;15(4):480-91.

• 21.

  2012

  Archana Thakur; Dana Schalk; Sanila H Sarkar; Zaid Al-Khadimi; Fazlul H Sarkar; Lawrence G Lum

  A Th1 cytokine-enriched microenvironment enhances tumor killing by activated T cells armed with bispecific antibodies and inhibits the development of myeloid-derived suppressor cells.

  Cancer immunology, immunotherapy : CII 2012;61(4):497-509.

• 22.

  2012

  Jianmei Wu; Patricia M Lorusso; Larry H Matherly; Jing Li

  Implications of plasma protein binding for pharmacokinetics and pharmacodynamics of the γ-secretase inhibitor RO4929097.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(7):2066-79.

• 23.

  2012

  Richard Wiegand; Jianmei Wu; Anthony F Shields; Patricia Lorusso; Jing Li

  Simultaneous determination of 1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl) uracil (FAU) and 1-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl) 5-methyluracil (FMAU) in human plasma by liquid chromatography/tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;891-892():64-70.

• 24.

  2012

  Zora Djuric; Richard K Severson; Ikuko Kato

  Association of dietary quercetin with reduced risk of proximal colon cancer.

  Nutrition and cancer 2012;64(3):351-60.

• 25.

  2012

  Albert Rosenberger; Heike Bickeböller; Valerie McCormack; Darren R Brenner; Eric J Duell; Anne Tjønneland; Soren Friis; Joshua E Muscat; Ping Yang; H-Erich Wichmann; et al.

  Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium.

  Carcinogenesis 2012;33(3):587-97.

• 26.

  2012

  Anthony F Shields

  PET imaging of tumor growth: not as easy as it looks.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(5):1189-91.

• 27.

  2012

  Zhanjun Hou; Sita Kugel Desmoulin; Erika Etnyre; Mary Olive; Benjamin Hsiung; Christina Cherian; Patrick A Wloszczynski; Kamiar Moin; Larry H Matherly

  Identification and functional impact of homo-oligomers of the human proton-coupled folate transporter.

  The Journal of biological chemistry 2012;287(7):4982-95.

• 28.

  2012

  J Wu; S Liu; G Liu; A Dombkowski; J Abrams; R Martin-Trevino; M S Wicha; S P Ethier; Z-Q Yang

  Identification and functional analysis of 9p24 amplified genes in human breast cancer.

  Oncogene 2012;31(3):333-41.

• 29.

  2012

  Jennifer M Rothberg; Mansoureh Sameni; Kamiar Moin; Bonnie F Sloane

  Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironment.

  Biochimica et biophysica acta 2012;1824(1):123-32.

• 30.

  2012

  Michael S Simon; Carol A Rosenberg; Rebecca J Rodabough; Phillip Greenland; Ira Ockene; Hemant K Roy; Dorothy S Lane; Jane A Cauley; Janardan Khandekar

  Prospective analysis of association between use of statins or other lipid-lowering agents and colorectal cancer risk.

  Annals of epidemiology 2012;22(1):17-27.

• 31.

  2012

  Rod D Braun; David Bissig; Robert North; Kerry S Vistisen; Bruce A Berkowitz

  Human tumor cell proliferation evaluated using manganese-enhanced MRI.

  PloS one 2012;7(2):e30572.

• 32.

  2012

  Mansoureh Sameni; Arulselvi Anbalagan; Mary B Olive; Kamiar Moin; Raymond R Mattingly; Bonnie F Sloane

  MAME models for 4D live-cell imaging of tumor: microenvironment interactions that impact malignant progression.

  Journal of visualized experiments : JoVE 2012;(60):.

• 33.

  2012

  George S Brush; Nicole A Najor; Alan A Dombkowski; Daniela Cukovic; Kara E Sawarynski

  Yeast IME2 functions early in meiosis upstream of cell cycle-regulated SBF and MBF targets.

  PloS one 2012;7(2):e31575.

• 34.

  2012

  Guohui Wang; Gang Liu; Xiaogang Wang; Seema Sethi; Rouba Ali-Fehmi; Judith Abrams; Ze Zheng; Kezhong Zhang; Stephen Ethier; Zeng-Quan Yang

  ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.

  BMC cancer 2012;12():225.

• 35.

  2012

  Young Suk Jung; Xu-Wen Liu; Rosemarie Chirco; Richard B Warner; Rafael Fridman; Hyeong-Reh Choi Kim

  TIMP-1 induces an EMT-like phenotypic conversion in MDCK cells independent of its MMP-inhibitory domain.

  PloS one 2012;7(6):e38773.

• 36.

  2012

  Archana Thakur; Lawrence G Lum; Dana Schalk; Asfar Azmi; Sanjeev Banerjee; Fazlul H Sarkar; Ramzi Mohommad

  Pan-Bcl-2 inhibitor AT-101 enhances tumor cell killing by EGFR targeted T cells.

  PloS one 2012;7(11):e47520.

• 37.

  2012

  Hitchintan Kaur; Shihong Mao; Quanwen Li; Mansoureh Sameni; Stephen A Krawetz; Bonnie F Sloane; Raymond R Mattingly

  RNA-Seq of human breast ductal carcinoma in situ models reveals aldehyde dehydrogenase isoform 5A1 as a novel potential target.

  PloS one 2012;7(12):e50249.

• 38.

  2011

  Archana Thakur; Oxana Norkina; Lawrence G Lum

  In vitro synthesis of primary specific anti-breast cancer antibodies by normal human peripheral blood mononuclear cells.

  Cancer immunology, immunotherapy : CII 2011;60(12):1707-20.

• 39.

  2011

  Lawrence G Lum; Archana Thakur

  Targeting T cells with bispecific antibodies for cancer therapy.

  BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2011;25(6):365-79.

• 40.

  2011

  Mary E Irwin; Natacha Bohin; Julie L Boerner

  Src family kinases mediate epidermal growth factor receptor signaling from lipid rafts in breast cancer cells.

  Cancer biology & therapy 2011;12(8):718-26.

• 41.

  2011

  Andrew P Neilson; Zora Djuric; Susan Land; Ikuko Kato

  Plasma levels of resistin-like molecule beta in humans.

  Cancer epidemiology 2011;35(5):485-9.

• 42.

  2011

  Shuping Yin; Liping Xu; Sudeshna Bandyopadhyay; Seema Sethi; Kaladhar B Reddy

  Cisplatin and TRAIL enhance breast cancer stem cell death.

  International journal of oncology 2011;39(4):891-8.

• 43.

  2011

  Sachin Gupta; Venkata Parsa; Lance K Heilbrun; Daryn W Smith; Brenda Dickow; Elisabeth Heath; Ulka Vaishampayan

  Safety and efficacy of molecularly targeted agents in patients with metastatic kidney cancer with renal dysfunction.

  Anti-cancer drugs 2011;22(8):794-800.

• 44.

  2011

  Anjali G Hinch; Arti Tandon; Nick Patterson; Yunli Song; Nadin Rohland; Cameron D Palmer; Gary K Chen; Kai Wang; Sarah G Buxbaum; Ermeg L Akylbekova; et al.

  The landscape of recombination in African Americans.

  Nature 2011;476(7359):170-5.

• 45.

  2011

  Amy F Roth; Irene Papanayotou; Nicholas G Davis

  The yeast kinase Yck2 has a tripartite palmitoylation signal.

  Molecular biology of the cell 2011;22(15):2702-15.

• 46.

  2011

  Haijun Zhang; Fanyan Meng; Sherwin Wu; Bas Kreike; Seema Sethi; Wei Chen; Fred R Miller; Guojun Wu

  Engagement of I-branching {beta}-1, 6-N-acetylglucosaminyltransferase 2 in breast cancer metastasis and TGF-{beta} signaling.

  Cancer research 2011;71(14):4846-56.

• 47.

  2011

  Michael S Simon; Cynthia A Thomson; Erin Pettijohn; Ikuko Kato; Rebecca J Rodabough; Dorothy Lane; F Allan Hubbell; Mary Jo O'Sullivan; Lucille Adams-Campbell; Charles P Mouton; et al.

  Racial differences in colorectal cancer incidence and mortality in the Women's Health Initiative.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(7):1368-78.

• 48.

  2011

  Subhendu Das; Philip E Pellett

  Spatial relationships between markers for secretory and endosomal machinery in human cytomegalovirus-infected cells versus those in uninfected cells.

  Journal of virology 2011;85(12):5864-79.

• 49.

  2011

  Jianmei Wu; Richard Wiegand; Patricia LoRusso; Jing Li

  Validation and implementation of a liquid chromatography/tandem mass spectrometry assay for quantitation of the total and unbound RO4929097, a γ-secretase inhibitor targeting Notch signaling, in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(19):1537-43.

• 50.

  2011

  Archana Thakur; Peter Littrup; Elyse N Paul; Barbara Adam; Lance K Heilbrun; Lawrence G Lum

  Induction of specific cellular and humoral responses against renal cell carcinoma after combination therapy with cryoablation and granulocyte-macrophage colony stimulating factor: a pilot study.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(5):457-67.

• 51.

  2011

  Nazik Hammad; Lance K Heilbrun; Sachin Gupta; Nishant Tageja; Philip A Philip; Anthony F Shields; Daryn Smith; Bassel F El-Rayes

  Squamous cell cancer of the anal canal in HIV-infected patients receiving highly active antiretroviral therapy: a single institution experience.

  American journal of clinical oncology 2011;34(2):135-9.

• 52.

  2011

  Jonathan W Wojtkowiak; Komal M Sane; Miriam Kleinman; Bonnie F Sloane; John J Reiners; Raymond R Mattingly

  Aborted autophagy and nonapoptotic death induced by farnesyl transferase inhibitor and lovastatin.

  The Journal of pharmacology and experimental therapeutics 2011;337(1):65-74.

• 53.

  2011

  Yong Yang; Deborah A Cochran; Mary D Gargano; Iryna King; Nayef K Samhat; Benjain P Burger; Katherine R Sabourin; Yuqing Hou; Junya Awata; David A D Parry; et al.

  Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50.

  Molecular biology of the cell 2011;22(7):976-87.

• 54.

  2011

  Song Chen; Hedeel Guy Evans; David R Evans

  FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells.

  The Journal of biological chemistry 2011;286(12):10201-9.

• 55.

  2011

  Ann G Schwartz; Angela S Wenzlaff; Cathryn H Bock; Julie J Ruterbusch; Wei Chen; Michele L Cote; Amanda S Artis; Alison L Van Dyke; Susan J Land; Curtis C Harris; et al.

  Admixture mapping of lung cancer in 1812 African-Americans.

  Carcinogenesis 2011;32(3):312-7.

• 56.

  2011

  Michele L Cote; Ramsi Haddad; David J Edwards; Govindaraja Atikukke; Shirish Gadgeel; Ayman O Soubani; Fulvio Lonardo; Gerold Bepler; Ann G Schwartz; Stephen P Ethier

  Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(3):627-30.

• 57.

  2011

  Haijun Zhang; Fanyan Meng; Gang Liu; Bin Zhang; Jun Zhu; Feng Wu; Stephen P Ethier; Fred Miller; Guojun Wu

  Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis.

  Cancer research 2011;71(4):1292-301.

• 58.

  2011

  M G Martínez-Hernández; L A Baiza-Gutman; A Castillo-Trápala; D Randall Armant

  Regulation of proteinases during mouse peri-implantation development: urokinase-type plasminogen activator expression and cross talk with matrix metalloproteinase 9.

  Reproduction (Cambridge, England) 2011;141(2):227-39.

• 59.

  2011

  Benchamart Moolmuang; Michael A Tainsky

  CREG1 enhances p16(INK4a) -induced cellular senescence.

  Cell cycle (Georgetown, Tex.) 2011;10(3):518-30.

• 60.

  2011

  Teena Chopra; Pranatharthi Chandrasekar; Hossein Salimnia; Lance K Heilbrun; Daryn Smith; George J Alangaden

  Recent epidemiology of Clostridium difficile infection during hematopoietic stem cell transplantation.

  Clinical transplantation 2011;25(1):E82-7.

• 61.

  2011

  Paolo Boffetta; Vijayvel Jayaprakash; Ping Yang; Kofi Asomaning; Joshua E Muscat; Ann G Schwartz; Zuo-Feng Zhang; Loic Le Marchand; Michele L Cote; Shawn M Stoddard; et al.

  Tobacco smoking as a risk factor of bronchioloalveolar carcinoma of the lung: pooled analysis of seven case-control studies in the International Lung Cancer Consortium (ILCCO).

  Cancer causes & control : CCC 2011;22(1):73-9.

• 62.

  2011

  Qunfang Li; Michael A Tainsky

  Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway.

  Cancer research 2011;71(1):255-65.

• 63.

  2011

  Bernadette C Victor; Arulselvi Anbalagan; Mona M Mohamed; Bonnie F Sloane; Dora Cavallo-Medved

  Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion.

  Breast cancer research : BCR 2011;13(6):R115.

• 64.

  2011

  Qunfang Li; Michael A Tainsky

  Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses.

  PloS one 2011;6(12):e28683.

• 65.

  2010

  Sachin Gupta; Venkata Parsa; Volkan Adsay; Lance K Heilbrun; Daryn Smith; Anthony F Shields; Donald Weaver; Philip A Philip; Bassel F El-Rayes

  Clinicopathological analysis of primary epithelial appendiceal neoplasms.

  Medical oncology (Northwood, London, England) 2010;27(4):1073-8.

• 66.

  2010

  Shirish M Gadgeel; Michele L Cote; Ann G Schwartz; Larry H Matherly; Antoinette Wozniak; Gerold Bepler

  Parameters for individualizing systemic therapy in non-small cell lung cancer.

  Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2010;13(6):196-204.

• 67.

  2010

  Carolyn V Ustach; Wei Huang; M Katie Conley-LaComb; Chen-Yong Lin; Mingxin Che; Judith Abrams; Hyeong-Reh Choi Kim

  A novel signaling axis of matriptase/PDGF-D/ß-PDGFR in human prostate cancer.

  Cancer research 2010;70(23):9631-40.

• 68.

  2010

  Janice M Kraniak; Daochun Sun; Raymond R Mattingly; John J Reiners; Michael A Tainsky

  The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors.

  Molecular and cellular biochemistry 2010;344(1-2):267-76.

• 69.

  2010

  Zeng-Quan Yang; Gang Liu; Aliccia Bollig-Fischer; Craig N Giroux; Stephen P Ethier

  Transforming properties of 8p11-12 amplified genes in human breast cancer.

  Cancer research 2010;70(21):8487-97.

• 70.

  2010

  Aliccia Bollig-Fischer; Michele Dziubinski; Alaina Boyer; Ramsi Haddad; Craig N Giroux; Stephen P Ethier

  HER-2 signaling, acquisition of growth factor independence, and regulation of biological networks associated with cell transformation.

  Cancer research 2010;70(20):7862-73.

• 71.

  2010

  B F El-Rayes; M Zalupski; T Bekai-Saab; L K Heilbrun; N Hammad; B Patel; S Urba; A F Shields; U Vaishampayan; S Dawson; et al.

  A phase II study of bevacizumab, oxaliplatin, and docetaxel in locally advanced and metastatic gastric and gastroesophageal junction cancers.

  Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(10):1999-2004.

• 72.

  2010

  Bassel F El-Rayes; Pallavi Jasti; Richard K Severson; Khaldoun Almhanna; Philip A Philip; Anthony Shields; Mark Zalupski; Lance K Heilbrun

  Impact of race, age, and socioeconomic status on participation in pancreatic cancer clinical trials.

  Pancreas 2010;39(7):967-71.

• 73.

  2010

  Timothy P McFarland; Michelle L Milstein; Steven E Cala

  Rough endoplasmic reticulum to junctional sarcoplasmic reticulum trafficking of calsequestrin in adult cardiomyocytes.

  Journal of molecular and cellular cardiology 2010;49(4):556-64.

• 74.

  2010

  Rebecca J W Cline; Heather Orom; Lisa Berry-Bobovski; Tanis Hernandez; C Brad Black; Ann G Schwartz; John C Ruckdeschel

  Community-level social support responses in a slow-motion technological disaster: the case of Libby, Montana.

  American journal of community psychology 2010;46(1-2):1-18.

• 75.

  2010

  Nancy L Saccone; Robert C Culverhouse; Tae-Hwi Schwantes-An; Dale S Cannon; Xiangning Chen; Sven Cichon; Ina Giegling; Shizhong Han; Younghun Han; Kaisu Keskitalo-Vuokko; et al.

  Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

  PLoS genetics 2010;6(8):.

• 76.

  2010

  Minsig Choi; Lance K Heilbrun; Raghu Venkatramanamoorthy; Jawana M Lawhorn-Crews; Mark M Zalupski; Anthony F Shields

  Using 18F-fluorodeoxyglucose positron emission tomography to monitor clinical outcomes in patients treated with neoadjuvant chemo-radiotherapy for locally advanced pancreatic cancer.

  American journal of clinical oncology 2010;33(3):257-61.

• 77.

  2010

  Archana Thakur; Lawrence G Lum

  Cancer therapy with bispecific antibodies: Clinical experience.

  Current opinion in molecular therapeutics 2010;12(3):340-9.

• 78.

  2010

  Nazik Hammad; Lance K Heilbrun; Philip A Philip; Anthony F Shields; Mark M Zalupski; Raghu Venkatramanamoorthy; Bassel F El-Rayes

  CA19-9 as a predictor of tumor response and survival in patients with advanced pancreatic cancer treated with gemcitabine based chemotherapy.

  Asia-Pacific journal of clinical oncology 2010;6(2):98-105.

• 79.

  2010

  Pengyuan Liu; Ping Yang; Xifeng Wu; Haris G Vikis; Yan Lu; Yian Wang; Ann G Schwartz; Susan M Pinney; Mariza de Andrade; Adi Gazdar; et al.

  A second genetic variant on chromosome 15q24-25.1 associates with lung cancer.

  Cancer research 2010;70(8):3128-35.

• 80.

  2010

  Komal M Sane; Michelle Mynderse; Daniel T Lalonde; Ivory S Dean; Jonathan W Wojtkowiak; Farid Fouad; Richard F Borch; John J Reiners; Richard A Gibbs; Raymond R Mattingly

  A novel geranylgeranyl transferase inhibitor in combination with lovastatin inhibits proliferation and induces autophagy in STS-26T MPNST cells.

  The Journal of pharmacology and experimental therapeutics 2010;333(1):23-33.

• 81.

  2010

  Quanwen Li; Albert B Chow; Raymond R Mattingly

  Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase kinase inhibitors.

  The Journal of pharmacology and experimental therapeutics 2010;332(3):821-8.

• 82.

  2010

  Pengyuan Liu; Haris G Vikis; Yan Lu; Yian Wang; Ann G Schwartz; Susan M Pinney; Ping Yang; Mariza de Andrade; Adi Gazdar; Colette Gaba; et al.

  Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(2):517-24.

• 83.

  2010

  Evan R Trivedi; Allison S Harney; Mary B Olive; Izabela Podgorski; Kamiar Moin; Bonnie F Sloane; Anthony G M Barrett; Thomas J Meade; Brian M Hoffman

  Chiral porphyrazine near-IR optical imaging agent exhibiting preferential tumor accumulation.

  Proceedings of the National Academy of Sciences of the United States of America 2010;107(4):1284-8.

• 84.

  2009

  Wei Chen; Debashis Ghosh; Trivellore E Raghunathan; Daniel J Sargent

  Bayesian variable selection with joint modeling of categorical and survival outcomes: an application to individualizing chemotherapy treatment in advanced colorectal cancer.

  Biometrics 2009;65(4):1030-40.

• 85.

  2009

  Sridhar Nimmagadda; Thomas J Mangner; Jawana M Lawhorn-Crews; Uwe Haberkorn; Anthony F Shields

  Herpes simplex virus thymidine kinase imaging in mice with (1-(2'-deoxy-2'-[18F]fluoro-1-β-D-arabinofuranosyl)-5-iodouracil) and metabolite (1-(2'-deoxy-2'-[18F]fluoro-1-β-D-arabinofuranosyl)-5-uracil).

  European journal of nuclear medicine and molecular imaging 2009;36(12):1987-93.

• 86.

  2009

  Christopher Jedeszko; Bernadette C Victor; Izabela Podgorski; Bonnie F Sloane

  Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ.

  Cancer research 2009;69(23):9148-55.

• 87.

  2009

  Ann G Schwartz; Michele L Cote; Angela S Wenzlaff; Susan Land; Christopher I Amos

  Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(10):1195-201.

• 88.

  2009

  Zora Djuric; Ann Edwards; Shashi Madan; Linda Darga; Jianwei Ren; Cassann Blake; Mathew Koletsky; Lance K Heilbrun

  Obesity is associated with atypia in breast ductal lavage of women with proliferative breast disease.

  Cancer epidemiology 2009;33(3-4):242-8.

• 89.

  2009

  Yan Liu; Pengyuan Liu; Weidong Wen; Michael A James; Yian Wang; Joan E Bailey-Wilson; Christopher I Amos; Susan M Pinney; Ping Yang; Mariza de Andrade; et al.

  Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1.

  Cancer research 2009;69(19):7844-50.

• 90.

  2009

  Peter J Littrup; Bassel Jallad; Priti Chandiwala-Mody; Monica D'Agostini; Barbara A Adam; David Bouwman

  Cryotherapy for breast cancer: a feasibility study without excision.

  Journal of vascular and interventional radiology : JVIR 2009;20(10):1329-41.

• 91.

  2009

  Izabela Podgorski; Bruce E Linebaugh; Jennifer E Koblinski; Deborah L Rudy; Mackenzie K Herroon; Mary B Olive; Bonnie F Sloane

  Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis.

  The American journal of pathology 2009;175(3):1255-69.

• 92.

  2009

  Venkata Parsa; Lance Heilbrun; Daryn Smith; Aastha Sethi; Ulka Vaishampayan

  Safety and efficacy of sorafenib therapy in patients with metastatic kidney cancer with impaired renal function.

  Clinical genitourinary cancer 2009;7(2):E10-5.

• 93.

  2009

  Ulka N Vaishampayan; Shanthi Marur; Lance K Heilbrun; Michael L Cher; Brenda Dickow; Daryn W Smith; Samir A Al Hasan; James Eliason

  Phase II trial of capecitabine and weekly docetaxel for metastatic castrate resistant prostate cancer.

  The Journal of urology 2009;182(1):317-23.

• 94.

  2009

  Alison L Van Dyke; Michele L Cote; Angie S Wenzlaff; Wei Chen; Judith Abrams; Susan Land; Craig N Giroux; Ann G Schwartz

  Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(6):1829-40.

• 95.

  2009

  Zora Djuric; Josephine Mirasolo; LaVern Kimbrough; Diane R Brown; Lance K Heilbrun; Lisa Canar; Raghu Venkatranamamoorthy; Michael S Simon

  A pilot trial of spirituality counseling for weight loss maintenance in African American breast cancer survivors.

  Journal of the National Medical Association 2009;101(6):552-64.

• 96.

  2009

  Dora Cavallo-Medved; Deborah Rudy; Galia Blum; Matthew Bogyo; Dejan Caglic; Bonnie F Sloane

  Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation.

  Experimental cell research 2009;315(7):1234-46.

• 97.

  2009

  Ming You; Daolong Wang; Pengyuan Liu; Haris Vikis; Michael James; Yan Lu; Yian Wang; Min Wang; Qiong Chen; Dongmei Jia; et al.

  Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(8):2666-74.

• 98.

  2009

  Michele L Cote; Wonsuk Yoo; Angela S Wenzlaff; Geoffrey M Prysak; Susan K Santer; Gina B Claeys; Alison L Van Dyke; Susan J Land; Ann G Schwartz

  Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women.

  Carcinogenesis 2009;30(4):626-35.

• 99.

  2009

  Ann G Schwartz; Michele L Cote; Angela S Wenzlaff; Alison Van Dyke; Wei Chen; John C Ruckdeschel; Shirish Gadgeel; Ayman O Soubani

  Chronic obstructive lung diseases and risk of non-small cell lung cancer in women.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(3):291-9.

• 100.

  2009

  Michelle L Milstein; Timothy D Houle; Steven E Cala

  Calsequestrin isoforms localize to different ER subcompartments: evidence for polymer and heteropolymer-dependent localization.

  Experimental cell research 2009;315(3):523-34.

• 101.

  2009

  Adi Laurentiu Tarca; Sorin Draghici; Purvesh Khatri; Sonia S Hassan; Pooja Mittal; Jung-Sun Kim; Chong Jai Kim; Juan Pedro Kusanovic; Roberto Romero

  A novel signaling pathway impact analysis.

  Bioinformatics (Oxford, England) 2009;25(1):75-82.

• 102.

  2009

  Mansoureh Sameni; Dora Cavallo-Medved; Julie Dosescu; Christopher Jedeszko; Kamiar Moin; Stefanie R Mullins; Mary B Olive; Deborah Rudy; Bonnie F Sloane

  Imaging and quantifying the dynamics of tumor-associated proteolysis.

  Clinical & experimental metastasis 2009;26(4):299-309.

• 103.

  2009

  Ayad M Al-Katib; Yuan Sun; Anton Scott Goustin; Asfar Sohail Azmi; Ben Chen; Amro Aboukameel; Ramzi M Mohammad

  SMI of Bcl-2 TW-37 is active across a spectrum of B-cell tumors irrespective of their proliferative and differentiation status.

  Journal of hematology & oncology 2009;2():8.

• 104.

  2009

  Elisabeth I Heath; Patricia M LoRusso; S Percy Ivy; Larry Rubinstein; Michaele C Christian; Lance K Heilbrun

  Theoretical and practical application of traditional and accelerated titration Phase I clinical trial designs: the Wayne State University experience.

  Journal of biopharmaceutical statistics 2009;19(3):414-23.

• 105.

  2009

  Ramzi M Mohammad; Jack Wu; Asfar S Azmi; Amro Aboukameel; Angela Sosin; Sherwin Wu; Dajun Yang; Shaomeng Wang; Ayad M Al-Katib

  An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals.

  Molecular cancer 2009;8():115.

• 106.

  2008

  Joshua T Dilworth; Jonathan W Wojtkowiak; Patricia Mathieu; Michael A Tainsky; John J Reiners; Raymond R Mattingly; Chad N Hancock

  Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033.

  Cancer biology & therapy 2008;7(12):1938-46.

• 107.

  2008

  Zora Djuric; Glee Vanloon; Katherine Radakovich; Nora M Dilaura; Lance K Heilbrun; Ananda Sen

  Design of a Mediterranean exchange list diet implemented by telephone counseling.

  Journal of the American Dietetic Association 2008;108(12):2059-65.

• 108.

  2008

  Quanwen Li; Raymond R Mattingly

  Restoration of E-cadherin cell-cell junctions requires both expression of E-cadherin and suppression of ERK MAP kinase activation in Ras-transformed breast epithelial cells.

  Neoplasia (New York, N.Y.) 2008;10(12):1444-58.

• 109.

  2008

  Bryan J Schneider; Gregory P Kalemkerian; Michael J Kraut; Antoinette J Wozniak; Francis P Worden; Daryn W Smith; Wei Chen; Shirish M Gadgeel

  Phase II study of celecoxib and docetaxel in non-small cell lung cancer (NSCLC) patients with progression after platinum-based therapy.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(12):1454-9.

• 110.

  2008

  Shirish M Gadgeel; Antoinette Wozniak; John C Ruckdeschel; Lance K Heilbrun; Raghu Venkatramanamoorthy; Ruth A Chaplen; Michael J Kraut; Gregory P Kalemkerian

  Phase II study of docetaxel and celecoxib, a cyclooxygenase-2 inhibitor, in elderly or poor performance status (PS2) patients with advanced non-small cell lung cancer.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(11):1293-300.

• 111.

  2008

  A L Fridman; M A Tainsky

  Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.

  Oncogene 2008;27(46):5975-87.

• 112.

  2008

  Pengyuan Liu; Haris G Vikis; Daolong Wang; Yan Lu; Yian Wang; Ann G Schwartz; Susan M Pinney; Ping Yang; Mariza de Andrade; Gloria M Petersen; et al.

  Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.

  Journal of the National Cancer Institute 2008;100(18):1326-30.

• 113.

  2008

  Alison L Van Dyke; Michele L Cote; Geoffrey M Prysak; Gina B Claeys; Angie S Wenzlaff; Valerie C Murphy; Fulvio Lonardo; Ann G Schwartz

  COX-2/EGFR expression and survival among women with adenocarcinoma of the lung.

  Carcinogenesis 2008;29(9):1781-7.

• 114.

  2008

  Minsig Choi; Peter Q Jiang; Lance K Heilbrun; Daryn W Smith; Shirish M Gadgeel

  Retrospective review of cancer patients > or =80 years old treated with chemotherapy at a comprehensive cancer center.

  Critical reviews in oncology/hematology 2008;67(3):268-72.

• 115.

  2008

  Yuan Sun; Jack Wu; Amro Aboukameel; Sanjeev Banerjee; Alan A Arnold; Jianyong Chen; Zaneta Nikolovska-Coleska; Yanqiong Lin; Xiaolan Ling; Dajun Yang; et al.

  Apogossypolone, a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins, effectively inhibits growth of diffuse large cell lymphoma cells in vitro and in vivo.

  Cancer biology & therapy 2008;7(9):1418-26.

• 116.

  2008

  Asfar Sohail Azmi; Zhiwei Wang; Ravshan Burikhanov; Vivek M Rangnekar; Guoping Wang; Jianyong Chen; Shaomeng Wang; Fazlul H Sarkar; Ramzi M Mohammad

  Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis.

  Molecular cancer therapeutics 2008;7(9):2884-93.

• 117.

  2008

  Mansoureh Sameni; Julie Dosescu; Kenneth M Yamada; Bonnie F Sloane; Dora Cavallo-Medved

  Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells.

  Molecular imaging 2008;7(5):199-213.

• 118.

  2008

  Zhiwei Wang; Wen Song; Amro Aboukameel; Mussop Mohammad; Guoping Wang; Sanjeev Banerjee; Dejuan Kong; Shaomeng Wang; Fazlul H Sarkar; Ramzi M Mohammad

  TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer.

  International journal of cancer. Journal international du cancer 2008;123(4):958-66.

• 119.

  2008

  Omid S Tehrani; Kirk A Douglas; Jawana M Lawhorn-Crews; Anthony F Shields

  Tracking cellular stress with labeled FMAU reflects changes in mitochondrial TK2.

  European journal of nuclear medicine and molecular imaging 2008;35(8):1480-8.

• 120.

  2008

  Anthony F Shields; Jawana M Lawhorn-Crews; David A Briston; Sajad Zalzala; Shirish Gadgeel; Kirk A Douglas; Thomas J Mangner; Lance K Heilbrun; Otto Muzik

  Analysis and reproducibility of 3'-Deoxy-3'-[18F]fluorothymidine positron emission tomography imaging in patients with non-small cell lung cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4463-8.

• 121.

  2008

  Jonathan W Wojtkowiak; Farid Fouad; Daniel T LaLonde; Miriam D Kleinman; Richard A Gibbs; John J Reiners; Richard F Borch; Raymond R Mattingly

  Induction of apoptosis in neurofibromatosis type 1 malignant peripheral nerve sheath tumor cell lines by a combination of novel farnesyl transferase inhibitors and lovastatin.

  The Journal of pharmacology and experimental therapeutics 2008;326(1):1-11.

• 122.

  2008

  Jin-Ah Cho; Pamela Osenkowski; Huiren Zhao; Seaho Kim; Marta Toth; Kristina Cole; Amro Aboukameel; Allen Saliganan; Lucia Schuger; R Daniel Bonfil; et al.

  The inactive 44-kDa processed form of membrane type 1 matrix metalloproteinase (MT1-MMP) enhances proteolytic activity via regulation of endocytosis of active MT1-MMP.

  The Journal of biological chemistry 2008;283(25):17391-405.

• 123.

  2008

  Robert Morris; Ronald D Alvarez; Stephen Andrews; John Malone; Christopher Bryant; Lance K Heilbrun; Daryn Smith; Veronica Schimp; Adnan Munkarah

  Topotecan weekly bolus chemotherapy for relapsed platinum-sensitive ovarian and peritoneal cancers.

  Gynecologic oncology 2008;109(3):346-52.

• 124.

  2008

  Christopher Jedeszko; Mansoureh Sameni; Mary B Olive; Kamiar Moin; Bonnie F Sloane

  Visualizing protease activity in living cells: from two dimensions to four dimensions.

  Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2008;Chapter 4():Unit 4.20.

• 125.

  2008

  Wei Chen; Debashis Ghosh; Trivellore E Raghunathan; Daniel J Sargent

  A false-discovery-rate-based loss framework for selection of interactions.

  Statistics in medicine 2008;27(11):2004-21.

• 126.

  2008

  Qunfang Li; Lin Tang; Paul Christopher Roberts; Janice M Kraniak; Aviva Levine Fridman; Olga I Kulaeva; Omid S Tehrani; Michael A Tainsky

  Interferon regulatory factors IRF5 and IRF7 inhibit growth and induce senescence in immortal Li-Fraumeni fibroblasts.

  Molecular cancer research : MCR 2008;6(5):770-84.

• 127.

  2008

  Quanwen Li; Stefanie Roshy Mullins; Bonnie F Sloane; Raymond R Mattingly

  p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer.

  Neoplasia (New York, N.Y.) 2008;10(4):314-29.

• 128.

  2008

  Sorin Draghici; Adi L Tarca; Longfei Yu; Stephen Ethier; Roberto Romero

  KUTE-BASE: storing, downloading and exporting MIAME-compliant microarray experiments in minutes rather than hours.

  Bioinformatics (Oxford, England) 2008;24(5):738-40.

• 129.

  2008

  Xiaoqing Zhao; Fayth K Yoshimura

  Expression of murine leukemia virus envelope protein is sufficient for the induction of apoptosis.

  Journal of virology 2008;82(5):2586-9.

• 130.

  2008

  Bassel F El-Rayes; Mark M Zalupski; Stephanie G Manza; Barbara Rusin; Ann Marie Ferris; Ulka Vaishampayan; Lance K Heilbrun; Raghu Venkatramanamoorthy; Anthony F Shields; Philip A Philip

  Phase-II study of dose attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer.

  Cancer chemotherapy and pharmacology 2008;61(2):283-9.

• 131.

  2008

  Heather Orom; Michele L Coté; Hector M González; Willie Underwood; Ann G Schwartz

  Family history of cancer: is it an accurate indicator of cancer risk in the immigrant population?

  Cancer 2008;112(2):399-406.

• 132.

  2008

  Alison L Van Dyke; Michele L Cote; Geoffrey Prysak; Gina B Claeys; Angie S Wenzlaff; Ann G Schwartz

  Regular adult aspirin use decreases the risk of non-small cell lung cancer among women.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(1):148-57.

• 133.

  2008

  Alan A Arnold; Amro Aboukameel; Jianyong Chen; Dajun Yang; Shaomeng Wang; Ayad Al-Katib; Ramzi M Mohammad

  Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model.

  Molecular cancer 2008;7():20.

• 134.

  2007

  Ann G Schwartz; Angela S Wenzlaff; Geoffrey M Prysak; Valerie Murphy; Michele L Cote; Sam C Brooks; Debra F Skafar; Fulvio Lonardo

  Reproductive factors, hormone use, estrogen receptor expression and risk of non small-cell lung cancer in women.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(36):5785-92.

• 135.

  2007

  Sarah A Krueger; Spencer J Collis; Michael C Joiner; George D Wilson; Brian Marples

  Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity.

  International journal of radiation oncology, biology, physics 2007;69(4):1262-71.

• 136.

  2007

  Ulka N Vaishampayan; Lance K Heilbrun; Cynthia Marsack; Daryn W Smith; Lawrence E Flaherty

  Phase II trial of pegylated interferon and thalidomide in malignant metastatic melanoma.

  Anti-cancer drugs 2007;18(10):1221-6.

• 137.

  2007

  Bernadette C Victor; Bonnie F Sloane

  Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function.

  Biological chemistry 2007;388(11):1131-40.

• 138.

  2007

  Sorin Draghici; Purvesh Khatri; Adi Laurentiu Tarca; Kashyap Amin; Arina Done; Calin Voichita; Constantin Georgescu; Roberto Romero

  A systems biology approach for pathway level analysis.

  Genome research 2007;17(10):1537-45.

• 139.

  2007

  Fatimah Nahhas; Sylvia C Dryden; Judith Abrams; Michael A Tainsky

  Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin.

  Molecular and cellular biochemistry 2007;303(1-2):221-30.

• 140.

  2007

  Sonia S Hassan; Roberto Romero; Adi L Tarca; Sorin Draghici; Beth Pineles; Andrej Bugrim; Nahla Khalek; Natalia Camacho; Pooja Mittal; Bo Hyun Yoon; et al.

  Signature pathways identified from gene expression profiles in the human uterine cervix before and after spontaneous term parturition.

  American journal of obstetrics and gynecology 2007;197(3):250.e1-7.

• 141.

  2007

  Purvesh Khatri; Calin Voichita; Khalid Kattan; Nadeem Ansari; Avani Khatri; Constantin Georgescu; Adi L Tarca; Sorin Draghici

  Onto-Tools: new additions and improvements in 2006.

  Nucleic acids research 2007;35(Web Server issue):W206-11.

• 142.

  2007

  Zora Djuric; Gang Chen; Jianwei Ren; Raghu Venkatramanamoorthy; Chandice Y Covington; Omer Kucuk; Lance K Heilbrun

  Effects of high fruit-vegetable and/or low-fat intervention on breast nipple aspirate fluid micronutrient levels.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(7):1393-9.

• 143.

  2007

  Aviva Levine Fridman; Rita Rosati; Qunfang Li; Michael A Tainsky

  Epigenetic and functional analysis of IGFBP3 and IGFBPrP1 in cellular immortalization.

  Biochemical and biophysical research communications 2007;357(3):785-91.

• 144.

  2007

  Adi L Tarca; Vincent J Carey; Xue-wen Chen; Roberto Romero; Sorin Drăghici

  Machine learning and its applications to biology.

  PLoS computational biology 2007;3(6):e116.

• 145.

  2007

  Donald R Schwartz; Kamiar Moin; Bin Yao; Lynn M Matrisian; Lisa M Coussens; Thomas H Bugge; Barbara Fingleton; Heath B Acuff; Mark Sinnamon; Hind Nassar; et al.

  Hu/Mu ProtIn oligonucleotide microarray: dual-species array for profiling protease and protease inhibitor gene expression in tumors and their microenvironment.

  Molecular cancer research : MCR 2007;5(5):443-54.

• 146.

  2007

  Ramzi M Mohammad; Anton Scott Goustin; Amro Aboukameel; Ben Chen; Sanjeev Banerjee; Guoping Wang; Zaneta Nikolovska-Coleska; Shaomeng Wang; Ayad Al-Katib

  Preclinical studies of TW-37, a new nonpeptidic small-molecule inhibitor of Bcl-2, in diffuse large cell lymphoma xenograft model reveal drug action on both Bcl-2 and Mcl-1.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2226-35.

• 147.

  2007

  Shirish M Gadgeel; John C Ruckdeschel; Elisabeth I Heath; Lance K Heilbrun; Raghu Venkatramanamoorthy; Antoinette Wozniak

  Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC).

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(4):299-305.

• 148.

  2007

  Basil F El-Rayes; Mark Zalupski; Anthony F Shields; Stephanie G Manza; Patricia LoRusso; Philip A Philip

  A phase I study of gemcitabine and uracil-ftorfar (UFT)/leucovorin.

  American journal of clinical oncology 2007;30(2):101-5.

• 149.

  2007

  K L Streicher; Z Q Yang; S Draghici; S P Ethier

  Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon.

  Oncogene 2007;26(14):2104-14.

• 150.

  2007

  Ozlem E Tulunay; Ileana I Enamorado; Omer Kucuk; Lance K Heilbrun; Jose E Otero; Hakan Korkmaz; Robert Blumberg; John R Jacobs

  Pilot study of intraoperative chemotherapy with cisplatin and 5-fluorouracil in patients with advanced squamous cell carcinoma of the head and neck.

  Head & neck 2007;29(3):267-71.

• 151.

  2007

  M L Cote; A S Wenzlaff; C H Bock; S J Land; S K Santer; D R Schwartz; A G Schwartz

  Combinations of cytochrome P-450 genotypes and risk of early-onset lung cancer in Caucasians and African Americans: a population-based study.

  Lung cancer (Amsterdam, Netherlands) 2007;55(3):255-62.

• 152.

  2007

  Ann G Schwartz; Geoffrey M Prysak; Cathryn H Bock; Michele L Cote

  The molecular epidemiology of lung cancer.

  Carcinogenesis 2007;28(3):507-18.

• 153.

  2007

  S Narreddy; S Mellon-Reppen; M H Abidi; J L Klein; E Peres; L K Heilbrun; D Smith; G Alangaden; P H Chandrasekar

  Non-bacterial infections in allogeneic non-myeloablative stem cell transplant recipients.

  Transplant infectious disease : an official journal of the Transplantation Society 2007;9(1):3-10.

• 154.

  2007

  Peter J Littrup; Abraham Ahmed; Hussein D Aoun; Daniel L Noujaim; Ted Harb; Sam Nakat; Khaled Abdallah; Barbara A Adam; Raghu Venkatramanamoorthy; Wael Sakr; et al.

  CT-guided percutaneous cryotherapy of renal masses.

  Journal of vascular and interventional radiology : JVIR 2007;18(3):383-92.

• 155.

  2007

  Ulka N Vaishampayan; Lance K Heilbrun; Anthony F Shields; Jawana Lawhorn-Crews; Karen Baranowski; Daryn Smith; Lawrence E Flaherty

  Phase II trial of interferon and thalidomide in metastatic renal cell carcinoma.

  Investigational new drugs 2007;25(1):69-75.

• 156.

  2007

  Jun Wang; Linda Mayernik; D Randall Armant

  Trophoblast adhesion of the peri-implantation mouse blastocyst is regulated by integrin signaling that targets phospholipase C.

  Developmental biology 2007;302(1):143-53.

• 157.

  2006

  Timothy D Houle; Michal L Ram; Walter J McMurray; Steven E Cala

  Different endoplasmic reticulum trafficking and processing pathways for calsequestrin (CSQ) and epitope-tagged CSQ.

  Experimental cell research 2006;312(20):4150-61.

• 158.

  2006

  Nasfat J Shehadeh; John F Ensley; Omer Kucuk; Carri Black; George H Yoo; John Jacobs; Ho-Sheng Lin; Lance K Heilbrun; Daryn Smith; Harold Kim

  Benefit of postoperative chemoradiotherapy for patients with unknown primary squamous cell carcinoma of the head and neck.

  Head & neck 2006;28(12):1090-8.

• 159.

  2006

  Basil F El-Rayes; Shirish Gadgeel; Anthony F Shields; Stephanie Manza; Patricia Lorusso; Philip A Philip

  Phase I study of bryostatin 1 and gemcitabine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(23):7059-62.

• 160.

  2006

  Joshua T Dilworth; Janice M Kraniak; Jonathan W Wojtkowiak; Richard A Gibbs; Richard F Borch; Michael A Tainsky; John J Reiners; Raymond R Mattingly

  Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1.

  Biochemical pharmacology 2006;72(11):1485-92.

• 161.

  2006

  Ki-Kyung Jung; Xu-Wen Liu; Rosemarie Chirco; Rafael Fridman; Hyeong-Reh Choi Kim

  Identification of CD63 as a tissue inhibitor of metalloproteinase-1 interacting cell surface protein.

  The EMBO journal 2006;25(17):3934-42.

• 162.

  2006

  Aviva Levine Fridman; Lin Tang; Olga I Kulaeva; Bin Ye; Qunfang Li; Fatimah Nahhas; Paul C Roberts; Susan J Land; Judith Abrams; Michael A Tainsky

  Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.

  The journals of gerontology. Series A, Biological sciences and medical sciences 2006;61(9):879-89.

• 163.

  2006

  Rekha T Tripathi; Lance K Heilbrun; Vikash Jain; Ulka N Vaishampayan

  Racial disparity in outcomes of a clinical trial population with metastatic renal cell carcinoma.

  Urology 2006;68(2):296-301.

• 164.

  2006

  Basil F El-Rayes; Shirish Gadgeel; Ralph Parchment; Patricia Lorusso; Philip A Philip

  A phase I study of flavopiridol and docetaxel.

  Investigational new drugs 2006;24(4):305-10.

• 165.

  2006

  Zora Djuric; Jianwei Ren; Olga Mekhovich; Raghu Venkatranamoorthy; Lance K Heilbrun

  Effects of high fruit-vegetable and/or low-fat intervention on plasma micronutrient levels.

  Journal of the American College of Nutrition 2006;25(3):178-87.

• 166.

  2006

  Huibin Yang; Raymond R Mattingly

  The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology.

  Molecular biology of the cell 2006;17(5):2177-89.

• 167.

  2006

  Zora Djuric; W Faye Cadwell; Lance K Heilbrun; Raghu Venkatramanamoorthy; Mary O Dereski; Randi Lan; Rita J Casey

  Relationships of psychosocial factors to dietary intakes of preadolescent girls from diverse backgrounds.

  Maternal & child nutrition 2006;2(2):79-90.

• 168.

  2006

  Janice M Kraniak; Judith Abrams; James E Nowak; Michael A Tainsky

  Antioxidant agents transiently inhibit aneuploidy progression in Li-Fraumeni cell strains.

  Molecular carcinogenesis 2006;45(3):141-56.

• 169.

  2006

  I Kato; J Ren; L K Heilbrun; Zora Djuric

  Intra- and inter-individual variability in measurements of biomarkers for oxidative damage in vivo: Nutrition and Breast Health Study.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2006;11(2):143-52.

• 170.

  2006

  Madhumita Chatterjee; Saroj Mohapatra; Alexei Ionan; Gagandeep Bawa; Rouba Ali-Fehmi; Xiaoju Wang; James Nowak; Bin Ye; Fatimah A Nahhas; Karen Lu; et al.

  Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays.

  Cancer research 2006;66(2):1181-90.

• 171.

  2006

  Ann G Schwartz; John C Ruckdeschel

  Familial lung cancer: genetic susceptibility and relationship to chronic obstructive pulmonary disease.

  American journal of respiratory and critical care medicine 2006;173(1):16-22.

• 172.

  2006

  Raymond R Mattingly; Janice M Kraniak; Joshua T Dilworth; Patricia Mathieu; Beverly Bealmear; James E Nowak; Joyce A Benjamins; Michael A Tainsky; John J Reiners

  The mitogen-activated protein kinase/extracellular signal-regulated kinase kinase inhibitor PD184352 (CI-1040) selectively induces apoptosis in malignant schwannoma cell lines.

  The Journal of pharmacology and experimental therapeutics 2006;316(1):456-65.

• 173.

  2006

  Bonnie F Sloane; Mansoureh Sameni; Izabela Podgorski; Dora Cavallo-Medved; Kamiar Moin

  Functional imaging of tumor proteolysis.

  Annual review of pharmacology and toxicology 2006;46():301-15.

• 174.

  2006

  Dieudonne Bangsi; Junying Zhou; Yezhou Sun; Nimesh P Patel; Linda L Darga; Lance K Heilbrun; Isaac J Powell; Richard K Severson; Richard B Everson

  Impact of a genetic variant in CYP3A4 on risk and clinical presentation of prostate cancer among white and African-American men.

  Urologic oncology 2006;24(1):21-7.

• 175.

  2006

  Lin Tang; Paul C Roberts; Janice M Kraniak; Qunfang Li; Michael A Tainsky

  Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2006;26(1):14-26.

• 176.

  2006

  Katherine Radakovich; Lance K Heilbrun; Raghu Venkatranamamoorthy; Samir Lababidi; David M Klurfeld; Zora Djuric

  Women participating in a dietary intervention trial maintain dietary changes without much effect on household members.

  Nutrition and cancer 2006;55(1):44-52.

• 177.

  2005

  Anthony F Shields; David A Briston; Samatha Chandupatla; Kirk A Douglas; Jawana Lawhorn-Crews; Jerry M Collins; Thomas J Mangner; Lance K Heilbrun; Otto Muzik

  A simplified analysis of [18F]3'-deoxy-3'-fluorothymidine metabolism and retention.

  European journal of nuclear medicine and molecular imaging 2005;32(11):1269-75.

• 178.

  2005

  Ann G Schwartz; Geoffrey M Prysak; Valerie Murphy; Fulvio Lonardo; Harvey Pass; Jan Schwartz; Sam Brooks

  Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7280-7.

• 179.

  2005

  Shirish M Gadgeel; Antoinette Wozniak; Ramesh R Boinpally; Richard Wiegand; Lance K Heilbrun; Vikas Jain; Ralph Parchment; Dimitrios Colevas; Marvin B Cohen; Patricia M LoRusso

  Phase I clinical trial of BMS-247550, a derivative of epothilone B, using accelerated titration 2B design.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6233-9.

• 180.

  2005

  Raymond E Menard; Andrew P Jovanovski; Raymond R Mattingly

  Active p21-activated kinase 1 rescues MCF10A breast epithelial cells from undergoing anoikis.

  Neoplasia (New York, N.Y.) 2005;7(7):638-45.

• 181.

  2005

  R B Ibrahim; E Peres; R Dansey; M H Abidi; E M Abella; M M Gumma; N Milan; D W Smith; L K Heilbrun; J Klein

  Safety of low-dose low-molecular-weight-heparins in thrombocytopenic stem cell transplantation patients: a case series and review of the literature.

  Bone marrow transplantation 2005;35(11):1071-7.

• 182.

  2005

  George H Yoo; Geetha Subramanian; Ramesh R Boinpally; Andrew Iskander; Nasfat Shehadeh; Jeffrey Oliver; Waleed Ezzat; Marie P Piechocki; John F Ensley; Ho-Sheng Lin; et al.

  An in vivo evaluation of docetaxel delivered intratumorally in head and neck squamous cell carcinoma.

  Archives of otolaryngology--head & neck surgery 2005;131(5):418-29.

• 183.

  2005

  Zhong Dong; R Daniel Bonfil; Sreenivasa Chinni; Xiyun Deng; J Carlos Trindade Filho; Margarida Bernardo; Ulka Vaishampayan; Mingxin Che; Bonnie F Sloane; Shijie Sheng; et al.

  Matrix metalloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue.

  The American journal of pathology 2005;166(4):1173-86.

• 184.

  2005

  Basil F El-Rayes; Anthony F Shields; Mark Zalupski; Lance K Heilbrun; Vikash Jain; Damita Terry; Ann Marie Ferris; Philip A Philip

  A phase II study of carboplatin and paclitaxel in adenocarcinoma of unknown primary.

  American journal of clinical oncology 2005;28(2):152-6.

• 185.

  2005

  Zora Djuric; Daniel W Visscher; Lance K Heilbrun; Gang Chen; Martin Atkins; Chandice Y Covington

  Influence of lactation history on breast nipple aspirate fluid yields and fluid composition.

  The breast journal 2005;11(2):92-9.

• 186.

  2005

  Ulka Vaishampayan; Lance K Heilbrun; Ralph E Parchment; Vikash Jain; James Zwiebel; Ramesh R Boinpally; Patricia LoRusso; Maha Hussain

  Phase II trial of fenretinide in advanced renal carcinoma.

  Investigational new drugs 2005;23(2):179-85.

• 187.

  2005

  Izabela Podgorski; Bruce E Linebaugh; Mansoureh Sameni; Christopher Jedeszko; Sunita Bhagat; Michael L Cher; Bonnie F Sloane

  Bone microenvironment modulates expression and activity of cathepsin B in prostate cancer.

  Neoplasia (New York, N.Y.) 2005;7(3):207-23.

• 188.

  2005

  Isaac J Powell; Susan J Land; Jyotirmoy Dey; Lance K Heilbrun; Mark R Hughes; Wael Sakr; Richard B Everson

  The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.

  Cancer 2005;103(3):528-37.

• 189.

  2005

  Xu-Wen Liu; Marcus E Taube; Ki-Kyung Jung; Zhong Dong; Yong J Lee; Stefanie Roshy; Bonnie F Sloane; Rafael Fridman; Hyeong-Reh Choi Kim

  Tissue inhibitor of metalloproteinase-1 protects human breast epithelial cells from extrinsic cell death: a potential oncogenic activity of tissue inhibitor of metalloproteinase-1.

  Cancer research 2005;65(3):898-906.

• 190.

  2005

  Ramzi M Mohammad; Shaomeng Wang; Amro Aboukameel; Ben Chen; Xihan Wu; Jianyong Chen; Ayad Al-Katib

  Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X(L) [(-)-gossypol] against diffuse large cell lymphoma.

  Molecular cancer therapeutics 2005;4(1):13-21.

• 191.

  2005

  Basil F El-Rayes; Camille S Norton; Wael Sakr; Zosia Maciorowski; Daryn Smith; Haline Pietraszkiewicz; Maria Del Mar Alonso; John F Ensley

  Cellular DNA content parameters as prognostic indicators in human astrocytomas.

  Journal of neuro-oncology 2005;71(2):85-9.

• 192.

  2005

  Michael S Simon; Beth A Mueller; Dennis Deapen; Glenn Copeland

  A comparison of record linkage yield for health research using different variable sets.

  Breast cancer research and treatment 2005;89(2):107-10.

• 193.

  2005

  Stuart Ratner; Wei-Zen Wei; Jeffrey Oliver; Jennifer Oliver

  Enhancement of T cell localization in mammary tumors through transient inhibition of T cell myosin function.

  Cellular immunology 2005;233(1):1-10.

• 194.

  2004

  Heinric Williams; Isaac J Powell; Susan J Land; Wael A Sakr; Mark R Hughes; Nimesh P Patel; Lance K Heilbrun; Richard B Everson

  Vitamin D receptor gene polymorphisms and disease free survival after radical prostatectomy.

  The Prostate 2004;61(3):267-75.

• 195.

  2004

  Isaac J Powell; Junying Zhou; Yezhou Sun; Wael A Sakr; N P Patel; Lance K Heilbrun; Richard B Everson

  CYP3A4 genetic variant and disease-free survival among white and black men after radical prostatectomy.

  The Journal of urology 2004;172(5 Pt 1):1848-52.

• 196.

  2004

  James G Granneman; Pipeng Li; Yuyan Lu; Jacqueline Tilak

  Seeing the trees in the forest: selective electroporation of adipocytes within adipose tissue.

  American journal of physiology. Endocrinology and metabolism 2004;287(3):E574-82.

• 197.

  2004

  Shadan Ali; Basil F El-Rayes; Lance K Heilbrun; Fazlul H Sarkar; John F Ensley; Omar Kucuk; Philip A Philip

  Cytochrome p450 and glutathione transferase expression in squamous cell cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4412-6.

• 198.

  2004

  Michael S Simon; Wei Du; Lawrence Flaherty; Philip A Philip; Patricia Lorusso; Cheryl Miree; Daryn Smith; Diane R Brown

  Factors associated with breast cancer clinical trials participation and enrollment at a large academic medical center.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(11):2046-52.

• 199.

  2004

  B F El-Rayes; A Shields; M Zalupski; L K Heilbrun; V Jain; D Terry; A Ferris; P A Philip

  A phase II study of carboplatin and paclitaxel in esophageal cancer.

  Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(6):960-5.

• 200.

  2004

  Ujjwal K Rout; Jun Wang; Bibhash C Paria; D Randall Armant

  Alpha5beta1, alphaVbeta3 and the platelet-associated integrin alphaIIbbeta3 coordinately regulate adhesion and migration of differentiating mouse trophoblast cells.

  Developmental biology 2004;268(1):135-51.

• 201.

  2004

  Chin Y Liu; Vikash Jain; Anthony F Shields; Lance K Heilbrun

  Efficacy and safety of reteplase for central venous catheter occlusion in patients with cancer.

  Journal of vascular and interventional radiology : JVIR 2004;15(1 Pt 1):39-44.

• 202.

  2004

  Zora Djuric; Samir Lababidi; Virginia E Uhley; Lance K Heilbrun

  Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from women participating in an intervention trial of low-fat and low-energy diets.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2004;9(1):93-101.

• 203.

  2004

  Gang Chen; Lance K Heilbrun; Raghu Venkatramanamoorthy; Vera Maranci; Jennifer N Redd; David M Klurfeld; Zora Djuric

  Effects of low-fat and/or high-fruit-and-vegetable diets on plasma levels of 8-isoprostane-F2alpha in the Nutrition and Breast Health study.

  Nutrition and cancer 2004;50(2):155-60.

• 204.

  2003

  Sana Al-Sukhun; Mark M Zalupski; Edgar Ben-Josef; Vainutis K Vaitkevicius; Philip A Philip; Renate Soulen; Donald Weaver; Volkan Adsay; Lance K Heilbrun; Kenneth Levin; et al.

  Chemoradiotherapy in the treatment of regional pancreatic carcinoma: a phase II study.

  American journal of clinical oncology 2003;26(6):543-9.

• 205.

  2003

  Li Zhong; Yingqun Wang; Perry Kannan; Michael A Tainsky

  Functional characterization of the interacting domains of the positive coactivator PC4 with the transcription factor AP-2alpha.

  Gene 2003;320():155-64.

• 206.

  2003

  B F El-Rayes; M M Zalupski; A F Shields; U Vaishampayan; L K Heilbrun; V Jain; V Adsay; J Day; P A Philip

  Phase II study of gemcitabine, cisplatin, and infusional fluorouracil in advanced pancreatic cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(15):2920-5.

• 207.

  2003

  Timothy R Schmidt; Jeffrey W Doan; Morris Goodman; Lawrence I Grossman

  Retention of a duplicate gene through changes in subcellular targeting: an electron transport protein homologue localizes to the golgi.

  Journal of molecular evolution 2003;57(2):222-8.

• 208.

  2003

  Sorin Draghici; Olga Kulaeva; Bruce Hoff; Anton Petrov; Soheil Shams; Michael A Tainsky

  Noise sampling method: an ANOVA approach allowing robust selection of differentially regulated genes measured by DNA microarrays.

  Bioinformatics (Oxford, England) 2003;19(11):1348-59.

• 209.

  2003

  Mansoureh Sameni; Julie Dosescu; Kamiar Moin; Bonnie F Sloane

  Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis.

  Molecular imaging 2003;2(3):159-75.

• 210.

  2003

  Olga I Kulaeva; Sorin Draghici; Lin Tang; Janice M Kraniak; Susan J Land; Michael A Tainsky

  Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

  Oncogene 2003;22(26):4118-27.

• 211.

  2003

  Stefanie Roshy; Bonnie F Sloane; Kamiar Moin

  Pericellular cathepsin B and malignant progression.

  Cancer metastasis reviews 2003;22(2-3):271-86.

• 212.

  2003

  Sylvia C Dryden; Fatimah A Nahhas; James E Nowak; Anton-Scott Goustin; Michael A Tainsky

  Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle.

  Molecular and cellular biology 2003;23(9):3173-85.

• 213.

  2003

  Basil F El-Rayes; Shadan Ali; Lance K Heilbrun; Samir Lababidi; David Bouwman; David Visscher; Philip A Philip

  Cytochrome p450 and glutathione transferase expression in human breast cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(5):1705-9.

• 214.

  2003

  Huibin Yang; Desma Cooley; Julie E Legakis; Qingyuan Ge; Rodrigo Andrade; Raymond R Mattingly

  Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex.

  The Journal of biological chemistry 2003;278(15):13278-85.

• 215.

  2003

  Maha Hussain; David C Smith; Basil F El-Rayes; Wei Du; Ulka Vaishampayan; Joseph Fontana; Wael Sakr; David Wood

  Neoadjuvant docetaxel and estramustine chemotherapy in high-risk/locallyadvanced prostate cancer.

  Urology 2003;61(4):774-80.

• 216.

  2003

  Zora Djuric; Virginia E Uhley; Lilian Naegeli; Samir Lababidi; Suhasini Macha; Lance K Heilbrun

  Plasma carotenoids, tocopherols, and antioxidant capacity in a 12-week intervention study to reduce fat and/or energy intakes.

  Nutrition (Burbank, Los Angeles County, Calif.) 2003;19(3):244-9.

• 217.

  2003

  Shirish M Gadgeel; Anthony F Shields; Lance K Heilbrun; Samir Labadidi; Mark Zalupski; Ruth Chaplen; Philip A Philip

  Phase II study of paclitaxel and carboplatin in patients with advanced gastric cancer.

  American journal of clinical oncology 2003;26(1):37-41.

• 218.

  2003

  S M Gadgeel; R R Boinpally; L K Heilbrun; A Wozniak; V Jain; B Redman; M Zalupski; R Wiegand; R Parchment; P M LoRusso

  A phase I clinical trial of spicamycin derivative KRN5500 (NSC 650426) using a phase I accelerated titration "2B" design.

  Investigational new drugs 2003;21(1):63-74.

• 219.

  2003

  K M Wahidur Rahman; Olivia Aranha; Fazlul H Sarkar

  Indole-3-carbinol (I3C) induces apoptosis in tumorigenic but not in nontumorigenic breast epithelial cells.

  Nutrition and cancer 2003;45(1):101-12.

• 220.

  2003

  Malathy P V Shekhar; Robert Pauley; Gloria Heppner

  Host microenvironment in breast cancer development: extracellular matrix-stromal cell contribution to neoplastic phenotype of epithelial cells in the breast.

  Breast cancer research : BCR 2003;5(3):130-5.

• 221.

  2003

  Maha Hussain; Mousumi Banerjee; Fazlul H Sarkar; Zora Djuric; Michael N Pollak; Daniel Doerge; Joseph Fontana; Sreenivasa Chinni; Joanne Davis; Jeffrey Forman; et al.

  Soy isoflavones in the treatment of prostate cancer.

  Nutrition and cancer 2003;47(2):111-7.

• 222.

  2002

  Edith J Mensah-Osman; Ayad M Al-Katib; Hai-Young Wu; Nadir I Osman; Ramzi M Mohammad

  2-[4-(7-chloro-2-quinoxalinyloxyphenoxy]-propionic acid (XK469), an inhibitor of topoisomerase (Topo) IIbeta, up-regulates Topo IIalpha and enhances Topo IIalpha-mediated cytotoxicity.

  Molecular cancer therapeutics 2002;1(14):1321-6.

• 223.

  2002

  Raymond R Mattingly; Richard A Gibbs; Raymond E Menard; John J Reiners

  Potent suppression of proliferation of a10 vascular smooth muscle cells by combined treatment with lovastatin and 3-allylfarnesol, an inhibitor of protein farnesyltransferase.

  The Journal of pharmacology and experimental therapeutics 2002;303(1):74-81.

• 224.

  2002

  Jianxin Mai; Mansoureh Sameni; Tom Mikkelsen; Bonnie F Sloane

  Degradation of extracellular matrix protein tenascin-C by cathepsin B: an interaction involved in the progression of gliomas.

  Biological chemistry 2002;383(9):1407-13.

• 225.

  2002

  Jennifer E Koblinski; Julie Dosescu; Mansoureh Sameni; Kamiar Moin; Katherine Clark; Bonnie F Sloane

  Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.

  The Journal of biological chemistry 2002;277(35):32220-7.

• 226.

  2002

  Ramzi M Mohammad; Amro Aboukameel; Sanaa Nabha; Dina Ibrahim; Ayad Al-Katib

  Rituximab, Cyclophosphamide, Dexamethasone (RCD) regimen induces cure in WSU-WM xenograft model and a partial remission in previously treated Waldenstrom's macroglobulinemia patient.

  Journal of drug targeting 2002;10(5):405-10.

• 227.

  2002

  Lulu Farhana; Marcia Dawson; Arun K Rishi; Yuxiang Zhang; Eric Van Buren; Charu Trivedi; Uwe Reichert; Guowei Fang; Marc W Kirschner; Joseph A Fontana

  Cyclin B and E2F-1 expression in prostate carcinoma cells treated with the novel retinoid CD437 are regulated by the ubiquitin-mediated pathway.

  Cancer research 2002;62(13):3842-9.

• 228.

  2002

  K M Poore; J B Depper; L K Heilbrun; S Lababidi; C Covington; Z Djuric

  Effect of participant motivation on rapid dietary changes in an intervention trial.

  Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 2002;15(3):211-4.

• 229.

  2002

  Jun Wang; Linda Mayernik; D Randall Armant

  Integrin signaling regulates blastocyst adhesion to fibronectin at implantation: intracellular calcium transients and vesicle trafficking in primary trophoblast cells.

  Developmental biology 2002;245(2):270-9.

• 230.

  2002

  Malathy P V Shekhar; Alex Lyakhovich; Daniel W Visscher; Henry Heng; Noelle Kondrat

  Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.

  Cancer research 2002;62(7):2115-24.

• 231.

  2002

  Ramzi Mohammad; Yousif Abubakr; Maria Dan; Amro Aboukameel; Christine Chow; Anwar Mohamed; Nayera Hamdy; Ayad Al-Katib

  Bcl-2 antisense oligonucleotides are effective against systemic but not central nervous system disease in severe combined immunodeficient mice bearing human t(14;18) follicular lymphoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(4):1277-83.

• 232.

  2002

  Safedin Beqaj; Sandhya Jakkaraju; Raymond R Mattingly; Desi Pan; Lucia Schuger

  High RhoA activity maintains the undifferentiated mesenchymal cell phenotype, whereas RhoA down-regulation by laminin-2 induces smooth muscle myogenesis.

  The Journal of cell biology 2002;156(5):893-903.

• 233.

  2002

  Zora Djuric; Samir Lababidi; Lance K Heilbrun; Janice B Depper; Kathleen M Poore; Virginia E Uhley

  Effect of low-fat and/or low-energy diets on anthropometric measures in participants of the women's diet study.

  Journal of the American College of Nutrition 2002;21(1):38-46.

• 234.

  2002

  Derek T Jane; Luis DaSilva; Jennifer Koblinski; Marshall Horwitz; Bonnie F Sloane; Michael J Dufresne

  Evidence for the involvement of cathepsin B in skeletal myoblast differentiation.

  Journal of cellular biochemistry 2002;84(3):520-31.

• 235.

  2002

  Michael S Simon; Dina Ibrahim; Lisa Newman; Miron Stano

  Efficacy and economics of hormonal therapies for advanced breast cancer.

  Drugs & aging 2002;19(6):453-63.

• 236.

  2002

  Zora Djuric; Kathleen M Poore; Janice B Depper; Virginia E Uhley; Samir Lababidi; Chandice Covington; David M Klurfeld; Michael S Simon; Omer Kucuk; Lance K Heilbrun

  Methods to increase fruit and vegetable intake with and without a decrease in fat intake: compliance and effects on body weight in the nutrition and breast health study.

  Nutrition and cancer 2002;43(2):141-51.

• 237.

  2001

  N R Wall; R M Mohammad; A M Al-Katib

  Mitogen-activated protein kinase is required for bryostatin 1-induced differentiation of the human acute lymphoblastic leukemia cell line Reh.

  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001;12(12):641-7.

• 238.

  2001

  Z Djuric; G Chen; D R Doerge; L K Heilbrun; O Kucuk

  Effect of soy isoflavone supplementation on markers of oxidative stress in men and women.

  Cancer letters 2001;172(1):1-6.

• 239.

  2001

  P A Philip; M M Zalupski; V K Vaitkevicius; P Arlauskas; R Chaplen; L K Heilbrun; V Adsay; D Weaver; A F Shields

  Phase II study of gemcitabine and cisplatin in the treatment of patients with advanced pancreatic carcinoma.

  Cancer 2001;92(3):569-77.

• 240.

  2001

  M Hussain; U Vaishampayan; W Du; B Redman; D C Smith

  Combination paclitaxel, carboplatin, and gemcitabine is an active treatment for advanced urothelial cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(9):2527-33.

• 241.

  2001

  A Premzl; V Puizdar; V Zavasnik-Bergant; N Kopitar-Jerala; T T Lah; N Katunuma; B F Sloane; V Turk; J Kos

  Invasion of ras-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases.

  Biological chemistry 2001;382(5):853-7.

• 242.

  2001

  M P Shekhar; J Werdell; S J Santner; R J Pauley; L Tait

  Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

  Cancer research 2001;61(4):1320-6.

• 243.

  2001

  Z Djuric; L K Heilbrun; S Lababidi; E Berzinkas; M S Simon; M A Kosir

  Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood of women scheduled for breast biopsy.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(2):147-9.

• 244.

  2001

  J A Zonder; A F Shields; M Zalupski; R Chaplen; L K Heilbrun; P Arlauskas; P A Philip

  A phase II trial of bryostatin 1 in the treatment of metastatic colorectal cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(1):38-42.

• 245.

  2001

  D W Visscher; P Nanjia-Makker; G Heppner; P V Shekhar

  Tamoxifen suppresses histologic progression to atypia and DCIS in MCFIOAT xenografts, a model of early human breast cancer.

  Breast cancer research and treatment 2001;65(1):41-7.

• 246.

  2001

  S M Nabha; R M Mohammad; N R Wall; J A Dutcher; B M Salkini; G R Pettit; A M Al-Katib

  Evaluation of combretastatin A-4 prodrug in a non-Hodgkin's lymphoma xenograft model: preclinical efficacy.

  Anti-cancer drugs 2001;12(1):57-63.

• 247.

  2001

  S Prakash; B J Foster; M Meyer; A Wozniak; L K Heilbrun; L Flaherty; M Zalupski; L Radulovic; M Valdivieso; P M LoRusso

  Chronic oral administration of CI-994: a phase 1 study.

  Investigational new drugs 2001;19(1):1-11.

• 248.

  2001

  N R Wall; F W Beck; A M Al-Katib; R M Mohammad

  Treatment-induced expression of anti-apoptotic proteins in WSU-CLL, a human chronic lymphocytic leukemia cell line.

  Journal of drug targeting 2001;9(5):329-39.

• 249.

  2001

  M S Simon; S Lababidi; Z Djuric; V Uhley; J Depper; C Kresge; D M Klurfeld; L K Heilbrun

  Comparison of dietary assessment methods in a low-fat dietary intervention program.

  Nutrition and cancer 2001;40(2):108-17.

• 250.

  2000

  R M Mohammad; N R Wall; J A Dutcher; A M Al-Katib

  The addition of bryostatin 1 to cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy improves response in a CHOP-resistant human diffuse large cell lymphoma xenograft model.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4950-6.

• 251.

  2000

  K M Rahman; O Aranha; A Glazyrin; S R Chinni; F H Sarkar

  Translocation of Bax to mitochondria induces apoptotic cell death in indole-3-carbinol (I3C) treated breast cancer cells.

  Oncogene 2000;19(50):5764-71.

• 252.

  2000

  C Trivedi; B Redman; L E Flaherty; O Kucuk; W Du; L K Heilbrun; M Hussain

  Weekly 1-hour infusion of paclitaxel. Clinical feasibility and efficacy in patients with hormone-refractory prostate carcinoma.

  Cancer 2000;89(2):431-6.

• 253.

  2000

  M S Simon; L K Heilbrun; D Stephens; S Lababidi; Z Djuric

  Recruitment for a pilot case control study of oxidative DNA damage and breast cancer risk.

  American journal of clinical oncology 2000;23(3):283-7.

• 254.

  2000

  S M Nabha; N R Wall; R M Mohammad; G R Pettit; A M Al-Katib

  Effects of combretastatin A-4 prodrug against a panel of malignant human B-lymphoid cell lines.

  Anti-cancer drugs 2000;11(5):385-92.

• 255.

  2000

  Y Zhang; A K Rishi; M I Dawson; R Tschang; L Farhana; M Boyanapalli; U Reichert; B Shroot; E C Van Buren; J A Fontana

  S-phase arrest and apoptosis induced in normal mammary epithelial cells by a novel retinoid.

  Cancer research 2000;60(7):2025-32.

• 256.

  2000

  I Ahmad; A M Al-Katib; F W Beck; R M Mohammad

  Sequential treatment of a resistant chronic lymphocytic leukemia patient with bryostatin 1 followed by 2-chlorodeoxyadenosine: case report.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1328-32.

• 257.

  2000

  M L Varterasian; R M Mohammad; M S Shurafa; K Hulburd; P A Pemberton; D H Rodriguez; V Spadoni; D S Eilender; A Murgo; N Wall; et al.

  Phase II trial of bryostatin 1 in patients with relapsed low-grade non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

  Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):825-8.

• 258.

  2000

  M P Shekhar; J Werdell; L Tait

  Interaction with endothelial cells is a prerequisite for branching ductal-alveolar morphogenesis and hyperplasia of preneoplastic human breast epithelial cells: regulation by estrogen.

  Cancer research 2000;60(2):439-49.

• 259.

  2000

  J Wang; L Mayernik; J F Schultz; D R Armant

  Acceleration of trophoblast differentiation by heparin-binding EGF-like growth factor is dependent on the stage-specific activation of calcium influx by ErbB receptors in developing mouse blastocysts.

  Development (Cambridge, England) 2000;127(1):33-44.

• 260.

  1999

  N R Wall; R M Mohammad; S M Nabha; G R Pettit; A M Al-Katib

  Modulation of cIAP-1 by novel antitubulin agents when combined with bryostatin 1 results in increased apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh.

  Biochemical and biophysical research communications 1999;266(1):76-80.

• 261.

  1999

  V Pethe; P V Shekhar

  Estrogen inducibility of c-Ha-ras transcription in breast cancer cells. Identification of functional estrogen-responsive transcriptional regulatory elements in exon 1/intron 1 of the c-Ha-ras gene.

  The Journal of biological chemistry 1999;274(43):30969-78.

• 262.

  1999

  N R Wall; R M Mohammad; A M Al-Katib

  Bax:Bcl-2 ratio modulation by bryostatin 1 and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-B acute lymphoblastic leukemia cell line, Reh.

  Leukemia research 1999;23(10):881-8.

• 263.

  1999

  R M Mohammad; C Limvarapuss; N R Wall; N Hamdy; F W Beck; G R Pettit; A Al-Katib

  A new tubulin polymerization inhibitor, auristatin PE, induces tumor regression in a human Waldenstrom's macroglobulinemia xenograft model.

  International journal of oncology 1999;15(2):367-72.

• 264.

  1999

  R M Mohammad; C Limvarapuss; N Hamdy; B S Dutcher; F W Beck; N R Wall; A M Al-Katib

  Treatment of a de novo fludarabine resistant-CLL xenograft model with bryostatin 1 followed by fludarabine.

  International journal of oncology 1999;14(5):945-50.

• 265.

  1999

  M S Simon; D R Brown; W Du; P LoRusso; C M Kellogg

  Accrual to breast cancer clinical trials at a university-affiliated hospital in metropolitan Detroit.

  American journal of clinical oncology 1999;22(1):42-6.

• 266.

  1999

  G P Kalemkerian; X Ou; M R Adil; R Rosati; M M Khoulani; S K Madan; G R Pettit

  Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification.

  Cancer chemotherapy and pharmacology 1999;43(6):507-15.

• 267.

  1999

  Z Djuric; V E Uhley; J B Depper; K M Brooks; S Lababidi; L K Heilbrun

  A clinical trial to selectively change dietary fat and/or energy intake in women: the Women's Diet Study.

  Nutrition and cancer 1999;34(1):27-35.

• 268.

  1998

  J Wang; U K Rout; I C Bagchi; D R Armant

  Expression of calcitonin receptors in mouse preimplantation embryos and their function in the regulation of blastocyst differentiation by calcitonin.

  Development (Cambridge, England) 1998;125(21):4293-302.

• 269.

  1998

  P V Shekhar; M L Chen; J Werdell; G H Heppner; F R Miller; J K Christman

  Transcriptional activation of functional endogenous estrogen receptor gene expression in MCF10AT cells: a model for early breast cancer.

  International journal of oncology 1998;13(5):907-15.

• 270.

  1998

  C C Calkins; M Sameni; J Koblinski; B F Sloane; K Moin

  Differential localization of cysteine protease inhibitors and a target cysteine protease, cathepsin B, by immuno-confocal microscopy.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(6):745-51.

• 271.

  1998

  H Wang; R M Mohammad; J Werdell; P V Shekhar

  p53 and protein kinase C independent induction of growth arrest and apoptosis by bryostatin 1 in a highly metastatic mammary epithelial cell line: In vitro versus in vivo activity.

  International journal of molecular medicine 1998;1(6):915-23.

• 272.

  1998

  M P Shekhar; P Nangia-Makker; S R Wolman; L Tait; G H Heppner; D W Visscher

  Direct action of estrogen on sequence of progression of human preneoplastic breast disease.

  The American journal of pathology 1998;152(5):1129-32.

• 273.

  1998

  Z Djuric; J B Depper; V Uhley; D Smith; S Lababidi; S Martino; L K Heilbrun

  Oxidative DNA damage levels in blood from women at high risk for breast cancer are associated with dietary intakes of meats, vegetables, and fruits.

  Journal of the American Dietetic Association 1998;98(5):524-8.

• 274.

  1998

  A M Al-Katib; M R Smith; W S Kamanda; G R Pettit; M Hamdan; A N Mohamed; B Chelladurai; R M Mohammad

  Bryostatin 1 down-regulates mdr1 and potentiates vincristine cytotoxicity in diffuse large cell lymphoma xenografts.

  Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(5):1305-14.

• 275.

  1998

  W Du; R Dansey; E M Abella; R Baynes; W P Peters; J Klein; A Akhtar; L Cherednikova; C Karanes

  Successful allogeneic bone marrow transplantation in selected patients over 50 years of age--a single institution's experience.

  Bone marrow transplantation 1998;21(10):1043-7.

• 276.

  1998

  M L Varterasian; R M Mohammad; D S Eilender; K Hulburd; D H Rodriguez; P A Pemberton; J M Pluda; M D Dan; G R Pettit; B D Chen; et al.

  Phase I study of bryostatin 1 in patients with relapsed non-Hodgkin's lymphoma and chronic lymphocytic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(1):56-62.

• 277.

  1998

  M M Zalupski; A F Shields; P A Philip; M Kraut; P LoRusso; L K Heilbrun; V Vaitkevicius

  Evaluation of pyrazoloacridine in patients with advanced pancreatic carcinoma.

  Investigational new drugs 1998;16(1):93-6.

• 278.

  1998

  Y Nishimura; M Sameni; B F Sloane

  Malignant transformation alters intracellular trafficking of lysosomal cathepsin D in human breast epithelial cells.

  Pathology oncology research : POR 1998;4(4):283-96.

• 279.

  1997

  P V Shekhar; J Werdell; V S Basrur

  Environmental estrogen stimulation of growth and estrogen receptor function in preneoplastic and cancerous human breast cell lines.

  Journal of the National Cancer Institute 1997;89(23):1774-82.

• 280.

  1997

  B Wang; H D Soule; F R Miller

  Transforming and oncogenic potential of activated c-Ha-ras in three immortalized human breast epithelial cell lines.

  Anticancer research 1997;17(6D):4387-94.

• 281.

  1997

  I J Powell; L Heilbrun; P L Littrup; A Franklin; J Parzuchowski; D Gelfand; W Sakr

  Outcome of African American men screened for prostate cancer: the Detroit Education and Early Detection Study.

  The Journal of urology 1997;158(1):146-9.

• 282.

  1997

  M S Simon; R K Severson

  Racial differences in breast cancer survival: the interaction of socioeconomic status and tumor biology.

  American journal of obstetrics and gynecology 1997;176(6):S233-9.

• 283.

  1997

  I J Powell; L K Heilbrun; W Sakr; D Grignon; J Montie; M Novallo; D Smith; J E Pontes

  The predictive value of race as a clinical prognostic factor among patients with clinically localized prostate cancer: a multivariate analysis of positive surgical margins.

  Urology 1997;49(5):726-31.

• 284.

  1997

  P J Chuba; M S Simon

  Trends in primary surgical and radiation therapy for localized breast cancer in the Detroit Metropolitan area 1973-1992.

  International journal of radiation oncology, biology, physics 1997;38(1):103-7.

• 285.

  1997

  K J Pienta; P S Esper; F Zwas; R Krzeminski; L E Flaherty

  Phase II chemoprevention trial of oral fenretinide in patients at risk for adenocarcinoma of the prostate.

  American journal of clinical oncology 1997;20(1):36-9.

• 286.

  1997

  Z Djuric; L K Heilbrun; S Lababidi; C K Everett-Bauer; M W Fariss

  Growth inhibition of MCF-7 and MCF-10A human breast cells by alpha-tocopheryl hemisuccinate, cholesteryl hemisuccinate and their ether analogs.

  Cancer letters 1997;111(1-2):133-9.

• 287.

  1997

  M S Simon; L K Heilbrun; A Boomer; C Kresge; J Depper; P N Kim; F Valeriote; S Martino

  A randomized trial of a low-fat dietary intervention in women at high risk for breast cancer.

  Nutrition and cancer 1997;27(2):136-42.

• 288.

  1997

  J F Schultz; L Mayernik; U K Rout; D R Armant

  Integrin trafficking regulates adhesion to fibronectin during differentiation of mouse peri-implantation blastocysts.

  Developmental genetics 1997;21(1):31-43.

• 289.

  1996

  A Nakeff; M A KuKuruga; J E Media; F Valeriote; M B Edelstein

  Quantitative measurements of the efficacy of new anti-cancer agents on fresh human AML cells by using multivariate flow analysis.

  Journal of experimental therapeutics & oncology 1996;1(6):361-7.

• 290.

  1996

  F R Miller; R J Pauley; B Wang

  Activated c-Ha-ras is not sufficient to produce the preneoplastic phenotype of human breast cell line MCF10AT.

  Anticancer research 1996;16(4A):1765-9.

• 291.

  1996

  M Hussain; M Kukuruga; S Biggar; W Sakr; G Cummings; J Ensley

  Prostate cancer: flow cytometric methods for detection of bone marrow micrometastases.

  Cytometry 1996;26(1):40-6.

• 292.

  1996

  T H Corbett; F A Valeriote; L Demchik; L Polin; C Panchapor; S Pugh; K White; J Knight; J Jones; L Jones; et al.

  Preclinical anticancer activity of cryptophycin-8.

  Journal of experimental therapeutics & oncology 1996;1(2):95-108.

• 293.

  1996

  Z Djuric; L K Heilbrun; M S Simon; D Smith; D A Luongo; P M LoRusso; S Martino

  Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood as a marker of breast cancer.

  Cancer 1996;77(4):691-6.

• 294.

  1996

  A N Mohamed; R Compean; M E Dan; M R Smith; A Al-Katib

  Clonal evolution of chronic lymphocytic leukemia to acute lymphoblastic leukemia.

  Cancer genetics and cytogenetics 1996;86(2):143-6.

• 295.

  1996

  M S Simon; R K Severson

  Racial differences in survival of female breast cancer in the Detroit metropolitan area.

  Cancer 1996;77(2):308-14.

• 296.

  1996

  P J Dawson; S R Wolman; L Tait; G H Heppner; F R Miller

  MCF10AT: a model for the evolution of cancer from proliferative breast disease.

  The American journal of pathology 1996;148(1):313-9.

• 297.

  1996

  R M Mohammad; A N Mohamed; M Y Hamdan; T Vo; B Chen; K Katato; Y A Abubakr; M C Dugan; A al-Katib

  Establishment of a human B-CLL xenograft model: utility as a preclinical therapeutic model.

  Leukemia 1996;10(1):130-7.

• 298.

  1996

  F R Miller

  Models of progression spanning preneoplasia and metastasis: the human MCF10AneoT.TGn series and a panel of mouse mammary tumor subpopulations.

  Cancer treatment and research 1996;83():243-63.

• 299.

  1996

  A N Mohamed; S Mahalak; S B Goldfarb; M Palutke

  Double minute chromosomes contain amplified c-myc oncogene sequences in acute myeloid leukemia.

  Hematopathology and molecular hematology 1996;10(4):193-9.

• 300.

  1995

  P LoRusso; B J Foster; E Poplin; J McCormick; M Kraut; L Flaherty; L K Heilbrun; M Valdivieso; L Baker

  Phase I clinical trial of pyrazoloacridine NSC366140 (PD115934).

  Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1487-93.

• 301.

  1995

  E Younes; G P Haas; B Dezso; E Ali; R L Maughan; M A Kukuruga; E Montecillo; J E Pontes; G G Hillman

  Local tumor irradiation augments the response to IL-2 therapy in a murine renal adenocarcinoma.

  Cellular immunology 1995;165(2):243-51.

• 302.

  1995

  R M Mohammad; H Diwakaran; A Maki; M A Emara; G R Pettit; B Redman; A al-Katib

  Bryostatin 1 induces apoptosis and augments inhibitory effects of vincristine in human diffuse large cell lymphoma.

  Leukemia research 1995;19(9):667-73.

• 303.

  1995

  X Gao; D J Grignon; T Chbihi; A Zacharek; Y Q Chen; W Sakr; A T Porter; J D Crissman; J E Pontes; I J Powell

  Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer.

  Urology 1995;46(2):227-37.

• 304.

  1995

  A N Mohamed; F Koppitch; M Varterasian; C Karanes; K L Yao; F H Sarkar

  BCR/ABL fusion located on chromosome 9 in chronic myeloid leukemia with a masked Ph chromosome.

  Genes, chromosomes & cancer 1995;13(2):133-7.

• 305.

  1995

  A N Mohamed; S A Ebrahim; F H Sarkar; J Uberti; S R Wolman

  Detection of M-bcr/abl fusion by fluorescence in situ hybridization (FISH) in a case of Ph negative CML.

  Cancer genetics and cytogenetics 1995;80(1):60-2.

• 306.

  1995

  G G Hillman; E Younes; D Visscher; E Ali; J S Lam; E Montecillo; J E Pontes; G P Haas; R K Puri

  Systemic treatment with interleukin-4 induces regression of pulmonary metastases in a murine renal cell carcinoma model.

  Cellular immunology 1995;160(2):257-63.

• 307.

  1995

  Z Djuric; T H Corbett; F A Valeriote; L K Heilbrun; L H Baker

  Detoxification ability and toxicity of quinones in mouse and human tumor cell lines used for anticancer drug screening.

  Cancer chemotherapy and pharmacology 1995;36(1):20-6.

• 308.

  1995

  R Krzeminski; F Zwas; P Esper; K Pienta

  Electroretinographic findings in subjects after administration of fenretinide.

  Documenta ophthalmologica. Advances in ophthalmology 1995;91(4):299-309.

• 309.

  1994

  R M Mohammad; A Maki; K Vistisen; A al-Katib

  Protein studies of human non-Hodgkin's B-lymphoma: appraisal by two-dimensional gel electrophoresis.

  Electrophoresis 1994;15(12):1566-72.

• 310.

  1994

  F R Miller; J Bukowski

  Mammary tumor stimulatory factors as well as mammastatin are produced by the normal human breast epithelial cell line MCF10A.

  International journal of cancer. Journal international du cancer 1994;59(2):296-7.

• 311.

  1994

  K J Pienta; B Redman; M Hussain; G Cummings; P S Esper; C Appel; L E Flaherty

  Phase II evaluation of oral estramustine and oral etoposide in hormone-refractory adenocarcinoma of the prostate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(10):2005-12.

• 312.

  1994

  F A Momin; M Zalupski; L K Heilbrun; L Flaherty; G Fyfe; L H Baker; B G Redman

  Phase II trial of recombinant human macrophage colony-stimulating factor in metastatic soft tissue sarcoma.

  Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;16(3):224-8.

• 313.

  1994

  R J Stachler; S L Hamlet; R H Mathog; L Jones; L K Heilbrun; L J Manov; J M O'Campo

  Swallowing of bolus types by postsurgical head and neck cancer patients.

  Head & neck 1994;16(5):413-9.

• 314.

  1994

  S L Hamlet; S Wilson; R J Stachler; W A Salwen; J Muz; L K Heilbrun

  Scintigraphic assessment of swallow efficiency postlaryngectomy.

  The Laryngoscope 1994;104(9):1159-62.

• 315.

  1994

  R M Mohammad; K Vistisen; A al-Katib

  Protein study of T and B acute lymphoblastic leukemia cell lines.

  Electrophoresis 1994;15(8-9):1218-24.

• 316.

  1994

  G G Hillman; M L Wolf; E Montecillo; E Younes; E Ali; J E Pontes; G P Haas

  Expansion of activated lymphocytes obtained from renal cell carcinoma in an automated hollow fiber bioreactor.

  Cell transplantation 1994;3(4):263-71.

• 317.

  1994

  G G Hillman; R K Puri; M A Kukuruga; J E Pontes; G P Haas

  Growth and major histocompatibility antigen expression regulation by IL-4, interferon-gamma (IFN-gamma) and tumour necrosis factor-alpha (TNF-alpha) on human renal cell carcinoma.

  Clinical and experimental immunology 1994;96(3):476-83.

• 318.

  1994

  B Chen; S Scheding; A Nakeff; Q Ruan

  Differential expression of mast cell growth factor receptor (c-kit) by peritoneal connective tissue-type mast cells and tissue culture-derived mast cells.

  Journal of leukocyte biology 1994;55(5):596-602.

• 319.

  1994

  S R Wolman; A N Mohamed; G H Heppner; H D Soule

  Chromosomal markers of immortalization in human breast epithelium.

  Genes, chromosomes & cancer 1994;10(1):59-65.

• 320.

  1994

  A Schöller; N J Hong; P Bischer; J J Reiners

  Short and long term effects of cytoskeleton-disrupting drugs on cytochrome P450 Cyp1a-1 induction in murine hepatoma 1c1c7 cells: suppression by the microtubule inhibitor nocodazole.

  Molecular pharmacology 1994;45(5):944-54.

• 321.

  1994

  Z Djuric; S Martino; L K Heilbrun; R W Hart

  Dietary modulation of oxidative DNA damage.

  Advances in experimental medicine and biology 1994;354():71-83.

• 322.

  1994

  R M Mohammad; A al-Katib; G R Pettit; L L Sensenbrenner

  Successful treatment of human Waldenström's macroglobulinemia with combination biological and chemotherapy agents.

  Cancer research 1994;54(1):165-8.

• 323.

  1993

  M H Hussain; I Powell; N Zaki; Z Maciorowski; W Sakr; M KuKuruga; D Visscher; G P Haas; J E Pontes; J F Ensley

  Flow cytometric DNA analysis of fresh prostatic resections. Correlation with conventional prognostic parameters in patients with prostate cancer.

  Cancer 1993;72(10):3012-9.

• 324.

  1993

  F R Miller; H D Soule; L Tait; R J Pauley; S R Wolman; P J Dawson; G H Heppner

  Xenograft model of progressive human proliferative breast disease.

  Journal of the National Cancer Institute 1993;85(21):1725-32.

• 325.

  1993

  R J Pauley; H D Soule; L Tait; F R Miller; S R Wolman; P J Dawson; G H Heppner

  The MCF10 family of spontaneously immortalized human breast epithelial cell lines: models of neoplastic progression.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 1993;2 Suppl 3():67-76.

• 326.

  1993

  J A Macoska; M A Micale; W A Sakr; P D Benson; S R Wolman

  Extensive genetic alterations in prostate cancer revealed by dual PCR and FISH analysis.

  Genes, chromosomes & cancer 1993;8(2):88-97.

• 327.

  1993

  M S Simon; M Hoff; M Hussein; S Martino; A Walt

  An evaluation of clinical follow-up in women with early stage breast cancer among physician members of the American Society of Clinical Oncology.

  Breast cancer research and treatment 1993;27(3):211-9.

• 328.

  1993

  M S Simon; D Lemanne; A G Schwartz; S Martino; G M Swanson

  Recent trends in the incidence of in situ and invasive breast cancer in the Detroit metropolitan area (1975-1988).

  Cancer 1993;71(3):769-74.

• 329.

  1993

  J F Ensley; Z Maciorowski; M Hassan; H Pietraszkiewicz; W Sakr; L K Heilbrun

  Variations in DNA aneuploid cell content during tumor dissociation in human colon and head and neck cancers analyzed by flow cytometry.

  Cytometry 1993;14(5):550-8.

• 330.

  1993

  R M Mohammad; A al-Katib; G R Pettit; L L Sensenbrenner

  Differential effects of bryostatin 1 on human non-Hodgkin's B-lymphoma cell lines.

  Leukemia research 1993;17(1):1-8.

• 331.

  1992

  E A Poplin; T Corbett; L Flaherty; P Tarasoff; B G Redman; M Valdivieso; L Baker

  Difluorodeoxycytidine (dFdC)--gemcitabine: a phase I study.

  Investigational new drugs 1992;10(3):165-70.

• 332.

  1992

  Z Djuric; M H Lu; S M Lewis; D A Luongo; X W Chen; L K Heilbrun; B A Reading; P H Duffy; R W Hart

  Oxidative DNA damage levels in rats fed low-fat, high-fat, or calorie-restricted diets.

  Toxicology and applied pharmacology 1992;115(2):156-60.

• 333.

  1992

  A J Walt; M Simon; G M Swanson

  The continuing dilemma of lobular carcinoma in situ.

  Archives of surgery (Chicago, Ill. : 1960) 1992;127(8):904-7; discussion 907-9.

• 334.

  1992

  B G Redman; L Flaherty; T H Chou; M Kraut; S Martino; M Simon; M Valdivieso; E Groves

  Phase I trial of recombinant macrophage colony-stimulating factor by rapid intravenous infusion in patients with cancer.

  Journal of immunotherapy : official journal of the Society for Biological Therapy 1992;12(1):50-4.

• 335.

  1992

  S Ragheb; R P Lisak

  Effect of clinical status and treatment on the frequency of CD5+ B cells in patients with myasthenia gravis.

  Neurology 1992;42(5):1076-80.

• 336.

  1992

  L G Lum; M Ueda

  Immunodeficiency and the role of suppressor cells after human bone marrow transplantation.

  Clinical immunology and immunopathology 1992;63(2):103-9.

• 337.

  1992

  R M Mohammad; A N Mohamed; M KuKuruga; M R Smith; A al-Katib

  A human B-cell lymphoma line with a de novo multidrug resistance phenotype.

  Cancer 1992;69(6):1468-74.

• 338.

  1992

  M S Simon; A G Schwartz; S Martino; G M Swanson

  Trends in the diagnosis of in situ breast cancer in the Detroit metropolitan area, 1973 to 1987.

  Cancer 1992;69(2):466-9.

• 339.

  1992

  M S Simon; E McKnight; A Schwartz; S Martino; G M Swanson

  Racial differences in cancer of the male breast--15 year experience in the Detroit metropolitan area.

  Breast cancer research and treatment 1992;21(1):55-62.

• 340.

  1991

  Z Djuric; L K Heilbrun; B A Reading; A Boomer; F A Valeriote; S Martino

  Effects of a low-fat diet on levels of oxidative damage to DNA to human peripheral nucleated blood cells.

  Journal of the National Cancer Institute 1991;83(11):766-9.

• 341.

  1991

  B G Redman; L Flaherty; T H Chou; A Nakeff; K Pillote; J Kaplan

  Sequential dacarbazine/cisplatin and interleukin-2 in metastatic melanoma: immunological effects of therapy.

  Journal of immunotherapy : official journal of the Society for Biological Therapy 1991;10(2):147-51.

• 342.

  1990

  J F Ensley; Z Maciorowski; H Pietraszkiewicz; F deBraud; W Sakr

  Methodology and clinical applications of cellular DNA content parameters determined by flow cytometry in squamous cell cancers of the head and neck.

  Cancer treatment and research 1990;52():225-42.

• 343.

  1990

  E Palomino; B R Meltsner; D Kessel; J P Horwitz

  Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.

  Journal of medicinal chemistry 1990;33(1):258-63.

• 344.

  1990

  J Brodfuehrer; F Valeriote; K Chan; L Heilbrun; T Corbett

  Flavone acetic acid and plasma protein binding.

  Cancer chemotherapy and pharmacology 1990;27(1):27-32.

• 345.

  1990

  Z Djuric; V K Malviya; G Deppe; J M Malone; D L McGunagle; L K Heilbrun; B A Reading; W D Lawrence

  Detoxifying enzymes in human ovarian tissues: comparison of normal and tumor tissues and effects of chemotherapy.

  Journal of cancer research and clinical oncology 1990;116(4):379-83.

• 346.

  1989

  W DeNeve; F Valeriote; M Edelstein; C Everett; M Bischoff

  In vivo DNA cross-linking by cyclophosphamide: comparison of human chronic lymphatic leukemia cells with mouse L1210 leukemia and normal bone marrow cells.

  Cancer research 1989;49(13):3452-6.

• 347.

  1989

  J F Ensley; Z Maciorowski; M Hassan; H Pietraszkiewicz; L Heilbrun; J A Kish; E Tapazoglou; J R Jacobs; M al-Sarraf

  Cellular DNA content parameters in untreated and recurrent squamous cell cancers of the head and neck.

  Cytometry 1989;10(3):334-8.

• 348.

  1989

  J F Ensley; J A Kish; A A Weaver; J R Jacobs; M Hassan; G Cummings; M Al-Sarraf

  The correlation of specific variables of tumor differentiation with response rate and survival in patients with advanced head and neck cancer treated with induction chemotherapy.

  Cancer 1989;63(8):1487-92.

• 349.

  1989

  G R Thrush; J L Placey; F A Valeriote; S P Lerman

  The CD4 cell dependency of SJL/J B-cell lymphomas as a target for cyclophosphamide therapy.

  Cancer communications 1989;1(5):301-10.

• 350.

  1988

  A N Mohamed; A Nakeff; R M Mohammad; M KuKuruga; A al-Katib

  Modulation of c-myc oncogene expression by phorbol ester and interferon-gamma: appraisal by flow cytometry.

  Oncogene 1988;3(4):429-35.

• 351.

  1988

  J L Evelhoch; M C Bissery; G G Chabot; N E Simpson; C L McCoy; L K Heilbrun; T H Corbett

  Flavone acetic acid (NSC 347512)-induced modulation of murine tumor physiology monitored by in vivo nuclear magnetic resonance spectroscopy.

  Cancer research 1988;48(17):4749-55.

• 352.

  1988

  J M Abdallah; M Kukuruga; A Nakeff; A S Prasad

  Cell cycle distribution defect in PHA-stimulated T lymphocytes of sickle cell disease patients.

  American journal of hematology 1988;28(4):279-81.

• 353.

  1988

  F R Miller; D McInerney; C Rogers; B E Miller

  Spontaneous fusion between metastatic mammary tumor subpopulations.

  Journal of cellular biochemistry 1988;36(2):129-36.

• 354.

  1986

  W Z Wei; K Malone; K Mahoney; G Heppner

  Characterization of lymphocytic infiltrates in normal, preneoplastic, and neoplastic mouse mammary tissues.

  Cancer research 1986;46(6):2680-5.

• 355.

  1985

  W Z Wei; R J Massey; G H Heppner

  A 3-dimensional tumor growth inhibition assay for testing monoclonal antibody cytotoxicity.

  Cancer immunology, immunotherapy : CII 1985;20(2):137-44.

• 356.

  1983

  B E Miller; L D Roi; L M Howard; F R Miller

  Quantitative selectivity of contact-mediated intercellular communication in a metastatic mouse mammary tumor line.

  Cancer research 1983;43(9):4102-7.

• 357.

  1981

  F R Miller; D Medina; G H Heppner

  Preferential growth of mammary tumors in intact mammary fatpads.

  Cancer research 1981;41(10):3863-7.

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